CN1189196C - Compound sarcandra glabra injection - Google Patents

Abstract

The present invention discloses a compound sarcandra glabra injection which is prepared from sarcandra and dyer's woad root, and the sarcandra and the dyer's woad root are extracted, abstracted and blended for preparing. The present invention has the advantages of no toxic or side effect, easy use, wide range of adaptability, good curative effect, rapid effect, exertion of the advantages of the compound compatibility of Chinese herbal medicines, etc. The present invention can be used for treating various kinds of livestock with gastroenteritis, diarrhea, dysentery, respiratory tract infection, pneumonia erysipelas, infuenza, rheumatic arthromyodynia, painful swollen joints and quadriplegia, and for treating fowl cholera, pullorum, etc.

Description

Compound sarcandra glabra injection

The present invention relates to a kind of injection made from Chinese herbal medicine.

At present the veterinary drug of treatment domestic animal, poultry disease is a lot, but great majority all are chemical drugss, easily has residually after the use in poultry, fowl body, produces toxic and side effects, to people's the healthy potential safety hazard that exists.

The objective of the invention is to: provide a kind of from natural plants effective component extracting and make the veterinary drug injection through the science compatibility, it does not produce any toxic side effects, and easy to use, to overcome the deficiency of existing medicine.

The present invention is achieved in that it is formed through extracting configuration by Herba Pileae Scriptae, Radix Isatidis:

1. get 1 part of system of Herba Pileae Scriptae herb coarse powder, decoct with water twice, each 2 hours, merge decoction liquor and be concentrated into the extractum shape, add 3 times of amount ethanol, stirring and dissolving, reflux 1 hour, low-temperature precipitation filters, filtrate recycling ethanol, use ethyl acetate extraction, extract reclaims ethyl acetate, and concentrated solution adds water low-temperature precipitation impurity, filter, transfer PH to 7～8, add 0.1% active carbon and be heated with stirring to and boil, be filtered to clear and bright standby;

2. getting the dried decoction pieces of Radix Isatidis decocts with water 2 times for 0.5 part, merge and concentrate after decoction liquor is filtered, be chilled to and under agitation add ethanol behind the room temperature and make and contain the alcohol amount and reach more than 60%, staticly settle filtration, decompression recycling ethanol, filtration is left standstill in cold preservation, filtrate adds ammonia and transfers PH to 8, and filtration is left standstill in cold preservation, and filtrate adds evanescence of heat ammonia, filtration is left standstill in cold preservation, and it is standby to add tween 80;

3. with Herba Pileae Scriptae extracting solution and isatis root extract mixing, filtration is left standstill in cold preservation, adds the injection water to capacity, makes every milliliter to contain effective ingredient total flavones amount and be not less than 5mg, fine straining, fill sealing by fusing, sterilization.

The present invention compared with prior art has and has no side effect, and is easy to use, wide adaptability, good effect, instant effect, advantages such as performance Chinese herb compound compatibility advantage.It can be used for treating gastroenteritis, diarrhoea, dysentery, the respiratory system infection of various domestic animals, pneumonia pig erysipelas, influenza, rheumatic Bi syndrome, arthralgia, quadriplegia; Fowl cholera, Pullorum Disease etc.

Embodiments of the invention:

1. get Herba Pileae Scriptae herb system coarse powder 10kg, add the moistening back of water and decoct twice, each 2 hours, merge decoction liquor and be concentrated into the extractum shape, add 3 times of amount ethanol, stirring and dissolving, reflux 1 hour, low-temperature precipitation filters, decompression filtrate recycling ethanol, get extract, use an amount of ethyl acetate extraction, extract reclaims ethyl acetate, concentrated solution adds suitable quantity of water low-temperature precipitation impurity, filters, and transfers PH to 7～8, add 0.1% active carbon and be heated with stirring to and boil, be filtered to clear and bright standby;

2. getting the dried decoction pieces 5kg of Radix Isatidis decocts with water 2 times, merge and concentrate after decoction liquor is filtered, be chilled to and under agitation slowly add 95% ethanol behind the room temperature and make and contain the alcohol amount and reach more than 60%, staticly settle filtration, decompression recycling ethanol, filtration is left standstill in cold preservation, filtrate adds ammonia transfers about PH to 8, and filtration is left standstill in cold preservation, and filtrate adds evanescence of heat ammonia, filtration is left standstill in cold preservation, and it is standby to add tween 80 100g;

3. with Herba Pileae Scriptae extracting solution and isatis root extract mixing, filtration is left standstill in cold preservation, put into mixer and add the injection water to capacity, make and contain the every ml of effective composition total flavones amount and must not be lower than 5mg, again through fine straining, fill sealing by fusing, 100 ℃ of flowing steam sterilizations are 30 minutes under the dust-free sterile condition, product inspection, packing warehouse-in.

Claims (1)

1, a kind of compound sarcandra glabra injection, it is formed through extracting configuration by Herba Pileae Scriptae, Radix Isatidis, it is characterized in that:

1. get 1 part of system of Herba Pileae Scriptae herb coarse powder, decoct with water twice, each 2 hours, merge decoction liquor and be concentrated into the extractum shape, add 3 times of amount ethanol, stirring and dissolving, reflux 1 hour, low-temperature precipitation filters, filtrate recycling ethanol, use ethyl acetate extraction, extract reclaims ethyl acetate, and concentrated solution adds water low-temperature precipitation impurity, filter, transfer PH to 7～8, add 0.1% active carbon and be heated with stirring to and boil, be filtered to clear and bright standby;

2. getting the dried decoction pieces of Radix Isatidis decocts with water 2 times for 0.5 part, merge and concentrate after decoction liquor is filtered, be chilled to and under agitation add ethanol behind the room temperature and make and contain the alcohol amount and reach more than 60%, staticly settle filtration, decompression recycling ethanol, filtration is left standstill in cold preservation, filtrate adds ammonia and transfers PH to 8, and filtration is left standstill in cold preservation, and filtrate adds evanescence of heat ammonia, filtration is left standstill in cold preservation, and it is standby to add tween 80;

3. with Herba Pileae Scriptae extracting solution and isatis root extract mixing, filtration is left standstill in cold preservation, adds the injection water to capacity, makes every milliliter to contain effective ingredient total flavones amount and be not less than 5mg, fine straining, fill sealing by fusing, sterilization.