CN1649568B - 用于治疗哮喘的药物组合物 - Google Patents

用于治疗哮喘的药物组合物 Download PDF

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Publication number
CN1649568B
CN1649568B CN02816685XA CN02816685A CN1649568B CN 1649568 B CN1649568 B CN 1649568B CN 02816685X A CN02816685X A CN 02816685XA CN 02816685 A CN02816685 A CN 02816685A CN 1649568 B CN1649568 B CN 1649568B
Authority
CN
China
Prior art keywords
formoterol fumarate
mometasone furoate
mometasone
metered dose
actuation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN02816685XA
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English (en)
Chinese (zh)
Other versions
CN1649568A (zh
Inventor
J·A·塞奎拉
S·A·夏普
J·L·哈特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23224164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1649568(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of CN1649568A publication Critical patent/CN1649568A/zh
Application granted granted Critical
Publication of CN1649568B publication Critical patent/CN1649568B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN02816685XA 2001-08-28 2002-08-27 用于治疗哮喘的药物组合物 Expired - Fee Related CN1649568B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31538601P 2001-08-28 2001-08-28
US60/315,386 2001-08-28
PCT/US2002/027336 WO2003020253A2 (en) 2001-08-28 2002-08-27 Pharmaceutical compositions for the treatment of asthma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201010156400A Division CN101856362A (zh) 2001-08-28 2002-08-27 用于治疗哮喘的药物组合物

Publications (2)

Publication Number Publication Date
CN1649568A CN1649568A (zh) 2005-08-03
CN1649568B true CN1649568B (zh) 2010-10-27

Family

ID=23224164

Family Applications (2)

Application Number Title Priority Date Filing Date
CN02816685XA Expired - Fee Related CN1649568B (zh) 2001-08-28 2002-08-27 用于治疗哮喘的药物组合物
CN201010156400A Pending CN101856362A (zh) 2001-08-28 2002-08-27 用于治疗哮喘的药物组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201010156400A Pending CN101856362A (zh) 2001-08-28 2002-08-27 用于治疗哮喘的药物组合物

Country Status (26)

Country Link
US (3) US20030114428A1 (enExample)
EP (3) EP2092935B1 (enExample)
JP (3) JP2005502675A (enExample)
KR (1) KR100970531B1 (enExample)
CN (2) CN1649568B (enExample)
AR (1) AR036358A1 (enExample)
AT (2) ATE430555T1 (enExample)
AU (1) AU2002313828B2 (enExample)
BR (1) BR0212089A (enExample)
CA (1) CA2457926A1 (enExample)
CO (1) CO5560551A2 (enExample)
CY (2) CY1109212T1 (enExample)
DE (2) DE60239648D1 (enExample)
DK (2) DK2092935T3 (enExample)
ES (3) ES2389480T3 (enExample)
HU (1) HUP0401514A3 (enExample)
MX (1) MXPA04001875A (enExample)
NO (1) NO20041277L (enExample)
NZ (1) NZ530987A (enExample)
PE (1) PE20030390A1 (enExample)
PL (1) PL209640B1 (enExample)
PT (2) PT1420759E (enExample)
SI (2) SI1420759T1 (enExample)
TW (1) TWI324934B (enExample)
WO (1) WO2003020253A2 (enExample)
ZA (1) ZA200401419B (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9904919D0 (en) * 1999-03-03 1999-04-28 Novartis Ag Organic compounds
CN100496608C (zh) * 2001-03-30 2009-06-10 洁垢技术有限公司 药用气溶胶制剂
GB0207906D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
ES2388537T3 (es) * 2002-08-23 2012-10-16 Merck Sharp & Dohme Corp. Inhalador dosificador que contiene una formulación en suspensión de aerosol
EP1785156B1 (en) * 2002-08-23 2012-06-27 Schering Corporation Metered dose inhaler containing an aerosol suspension formulation
SI1542904T1 (sl) * 2002-08-27 2008-06-30 Schering Corp Postopek za izdelavo inhalacijskih formulacij z merjenim odmerkom
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
JP2007509147A (ja) * 2003-10-20 2007-04-12 シェーリング コーポレイション 薬学的エアロゾル組成物
EP1925293A3 (en) * 2003-10-20 2010-01-13 Schering Corporation Pharmaceutical aerosol compositions
ES2340777T3 (es) * 2004-01-21 2010-06-09 Schering Corporation Metodo de tratamiento de la rinosinusitis aguda.
US20110053999A1 (en) * 2004-03-03 2011-03-03 Daley Thomas E 4-methylpyrazole formulations for inhibiting ethanol intolerance
WO2006040598A2 (en) * 2004-10-12 2006-04-20 Generics (Uk) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
EP2484382A1 (en) 2005-03-30 2012-08-08 Schering Corporation Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form
CA2641616A1 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
KR20100004993A (ko) * 2007-02-09 2010-01-13 쉐링 코포레이션 안정한 약제학적 약물 에어로졸
US20080253970A1 (en) * 2007-02-09 2008-10-16 Schering Corporation Stable Pharmaceutical Drug Products
GB0714239D0 (en) * 2007-07-20 2007-08-29 Glaxo Group Ltd Method
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
WO2009089422A2 (en) * 2008-01-10 2009-07-16 Schering Corporation Inhalation drug products, systems and uses
GB0801876D0 (en) 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
PT2435025T (pt) * 2009-05-29 2016-11-11 Pearl Therapeutics Inc Administração, por via respiratória, de agentes activos
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
WO2011027247A1 (en) 2009-09-03 2011-03-10 Sulur Subramaniam Vanangamudi An antifungal cream comprising terbinafine hydrochloride
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
PT2467136E (pt) * 2009-12-07 2014-08-26 Raptor Therapeutics Inc Formulações de 4-metilpirazol
WO2011101830A1 (en) 2010-02-22 2011-08-25 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer and clobetasone, and a process to make it
PH12012501666A1 (en) 2010-02-22 2012-11-05 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, a corticosteroid - betamethasone dipropionate, and a process to make it
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
WO2012017368A1 (en) 2010-08-02 2012-02-09 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, beclomethasone dipropionate and a process to make it
WO2012049543A1 (en) 2010-10-15 2012-04-19 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer and a corticosteroid, and a process to make it
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
KR102017915B1 (ko) * 2011-10-11 2019-09-03 키에시 파르마슈티시 엣스. 피. 에이. 지방산으로 코팅된 베타-작용제의 결정미세입자
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス,インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
US9360400B2 (en) 2014-06-30 2016-06-07 Proveris Scientific Corporation Sampling apparatus for determining the amount and uniformity of a delivered dose of drug and related methods
GB2545025A (en) * 2015-12-04 2017-06-07 Mexichem Fluor Sa De Cv Pharmaceutical composition
CN112472689B (zh) 2015-12-04 2023-01-17 墨西哥氟石股份公司 药物组合物
CA3016890A1 (en) 2016-03-09 2017-09-14 Proveris Scientific Corporation Methods for measuring dose content uniformity performance of inhaler and nasal devices
CN106619658B (zh) * 2016-12-28 2022-02-08 四川普锐特药业有限公司 一种医用气溶胶制剂及定量吸入气雾剂
WO2021219495A1 (en) 2020-04-28 2021-11-04 Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch Methods for treating or preventing a viral infection or inhibiting viral replication
EP4228725A4 (en) 2020-10-15 2024-11-06 Proveris Scientific Corporation SYSTEMS AND METHODS FOR INHALATOR TESTING

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
PT656206E (pt) * 1991-06-10 2001-11-30 Schering Corp Formulacoes de aerossois sem clorofluorocarbonetos
US6250300B1 (en) * 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
JP4155594B2 (ja) * 1994-12-22 2008-09-24 アストラゼネカ・アクチエボラーグ エアゾール製剤
GB9612297D0 (en) * 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
CO4900027A1 (es) * 1996-08-29 2000-03-27 Schering Corp Formulaciones en aerosol de furoato de mometasona sin cloro- fluorocarburos .
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US6503537B2 (en) * 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
EP1133301A1 (en) * 1998-11-26 2001-09-19 Britannia Pharmaceuticals Limited Anti-asthmatic combinations comprising surface active phospholipids
AR022695A1 (es) * 1999-01-28 2002-09-04 Schering Corp PORTADOR SoLIDO PARTICULADO Y MÉTODO PARA PROVEER CONTROL DE LA PARTICULADA PARA LA DISTRIBUCIoN DE TAMANO DE PARTíCULAS Y DE CONTENIDO AMORFO CONVERTIBLE DURANTE SU PREPARACION
GB9904919D0 (en) * 1999-03-03 1999-04-28 Novartis Ag Organic compounds
SE9900833D0 (sv) * 1999-03-09 1999-03-09 Astra Ab Novel combination
US6156294A (en) * 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
BR0107764A (pt) * 2000-01-20 2002-11-12 Basilea Pharmaceutica Ag Composições de peptìdeo cìclico nasalmente administráveis
GB0009612D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic formulations
AU2001278115A1 (en) * 2000-08-04 2002-02-18 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
TW200301698A (en) * 2001-12-21 2003-07-16 Bristol Myers Squibb Co Acridone inhibitors of IMPDH enzyme

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
奚念朱编.药剂学 第3版.人民卫生出版社,1996,66,415,419,422,426页.
奚念朱编.药剂学 第3版.人民卫生出版社,1996,66,415,419,422,426页. *

Also Published As

Publication number Publication date
JP2010138184A (ja) 2010-06-24
CO5560551A2 (es) 2005-09-30
CN1649568A (zh) 2005-08-03
ES2361805T3 (es) 2011-06-22
BR0212089A (pt) 2004-08-03
HUP0401514A2 (hu) 2004-12-28
DE60239648D1 (de) 2011-05-12
PL368897A1 (en) 2005-04-04
JP2009185075A (ja) 2009-08-20
HK1128428A1 (en) 2009-10-30
NZ530987A (en) 2006-08-31
PE20030390A1 (es) 2003-04-24
EP1420759A2 (en) 2004-05-26
HK1151987A1 (en) 2012-02-17
ES2325316T3 (es) 2009-09-01
EP1420759B1 (en) 2009-05-06
US20050147565A1 (en) 2005-07-07
DE60232251D1 (de) 2009-06-18
CY1109212T1 (el) 2014-07-02
HK1060972A1 (en) 2004-09-03
KR100970531B1 (ko) 2010-07-16
SI1420759T1 (sl) 2009-10-31
ZA200401419B (en) 2005-01-26
US20030114428A1 (en) 2003-06-19
EP2092935B1 (en) 2011-03-30
MXPA04001875A (es) 2004-06-15
CA2457926A1 (en) 2003-03-13
AR036358A1 (es) 2004-09-01
AU2002313828B2 (en) 2005-09-08
CY1111726T1 (el) 2015-10-07
ES2389480T3 (es) 2012-10-26
DK2092935T3 (da) 2011-07-18
SI2092935T1 (sl) 2011-07-29
EP2092935A1 (en) 2009-08-26
WO2003020253A3 (en) 2003-05-22
EP2319494A1 (en) 2011-05-11
WO2003020253A2 (en) 2003-03-13
US20100143269A1 (en) 2010-06-10
ATE503461T1 (de) 2011-04-15
PT1420759E (pt) 2009-06-30
EP2319494B1 (en) 2012-06-13
JP2005502675A (ja) 2005-01-27
ATE430555T1 (de) 2009-05-15
PL209640B1 (pl) 2011-09-30
CN101856362A (zh) 2010-10-13
HUP0401514A3 (en) 2012-08-28
KR20040031002A (ko) 2004-04-09
JP5170789B2 (ja) 2013-03-27
NO20041277L (no) 2004-03-26
DK1420759T3 (da) 2009-08-03
TWI324934B (en) 2010-05-21
PT2092935E (pt) 2011-05-31

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