CN1634115A - Acne removing cream - Google Patents
Acne removing cream Download PDFInfo
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- CN1634115A CN1634115A CN 200410094860 CN200410094860A CN1634115A CN 1634115 A CN1634115 A CN 1634115A CN 200410094860 CN200410094860 CN 200410094860 CN 200410094860 A CN200410094860 A CN 200410094860A CN 1634115 A CN1634115 A CN 1634115A
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- moroxydine
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Abstract
The invention discloses an acne removing cream which comprises (by weight proportions), metronidazole 10-20 parts, moroxydine 5-20 parts, compound ketoconazole ointment 3-5 parts, lincomycin hydrochloride and lidocaine hydrochloride 3-5 parts, bee honey as auxiliary materials 30-50 parts.
Description
Technical field the present invention relates to a kind of medicine of external, is a kind of pharmaceutical composition acne removing cream for the treatment of acne specifically.
The background technology acne is the dermatosis of teenager pilosity, and the male is higher than the women, mostly occurs at facial and breast, back, and forehead is easily to send out the position, shows as black head acne, pimple, abscess etc.Its pathogenic factor is a lot, and main cause is the endocrine disturbance, and sebum secretion increases, and makes hair follicle, sebaceous gland keratinization thromboembolism simultaneously, and sebum deposits and forms fat bolt, i.e. acne in hair follicle.The a large amount of breedings of anaerobe such as propionibacterium acnes cause inflammation, and the patient grabs, squeezes through hands commonly used simultaneously, causes infection suppurates, and what have seriously stays speckle.The makeup and the medicine of treatment acne are a lot of at present, as using antibiotics metronidazole and vitamin B
6Cooperation or oral medicine acne are clear, and certain effect is all arranged, but are easy to recurrence, bring heavy burden economically, mentally for a lot of patients, make some patients lose the confidence of thorough healing.
Summary of the invention the object of the present invention is to provide a kind of pharmaceutical composition acne removing cream for the treatment of acne, uses this pharmaceutical composition that acne is not recurred, and thoroughly cures.
Technical scheme of the present invention is as follows:
Medicine of the present invention is made up of following parts of medicines by weight:
30～50 parts of 10～20 parts of metronidazoles, 5～20 parts of moroxydines, 3～5 parts of compound ketoconazole ointments, 3～5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
The preferred version of above-mentioned composition is: 30～50 parts of 12～20 parts of metronidazoles, 3～5 parts of 11～20 parts of compound ketoconazole ointments of moroxydine, 3～5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
The further preferred version of above-mentioned composition is 50 parts of 20 parts of metronidazoles, 5 parts of 20 parts of compound ketoconazole ointments of moroxydine, 5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Collocation method is with Metronidazole Tablet and moroxydine sheet levigation, adds in the Mel to mix well, and adds compound ketoconazole ointment and lincomycin hydrochloride and lidocaine hydrochloride gel again and mixes well and get final product.
Use and directly be coated with the affected part, 2～3 times/day, 1～2g/ time.
This compositions can be made ointment, gel, the liniment of external with other adjuvants of interpolation.
Metronidazole Tablet has killing action to anaerobe, and the metabolite that it generates when human body reduces also has the anaerobe resistant effect, suppresses DNA (deoxyribonucleic acid) synthetic of antibacterial, thereby disturbs the growth, breeding of antibacterial, finally cause antibacterial death.
The moroxydine sheet, promptly the moroxydine hydrochloride sheet can suppress virus breeding.
Compound ketoconazole ointment, its key component are ketoconazole 1% and clobetasol propionate 0.05%.Ketoconazole belongs to the imidazoles antifungal agent, and clobetasol propionate belongs to the potent 17-hydroxy-11-dehydrocorticosterone of external, and effect has stronger blood capillary contraction and antiinflammatory action rapidly.
Lincomycin hydrochloride and lidocaine hydrochloride gel is a bacteriostatic antibiotic, and its key component is lincomycin hydrochloride, lidocaine hydrochloride.
The invention has the advantages that: 1, using this medicine treatment acne effective percentage is 100%, and the cure rate height does not recur, and therapeutic effect sees Table 1.2, the effective ingredient that contains antiviral, antifungal, antibacterium and 17-hydroxy-11-dehydrocorticosterone in this medicine, drug combination has the Comprehensive Treatment effect to acne and the infection that causes.3, this medicine instant effect makes skin recover moist, leaves no trace.4, with existing patent medicine formulated in combination, medicine is easy to get, and preparation is simple.
Specific embodiment embodiment 1: 50 parts of 20 parts of metronidazoles, 5 parts of 20 parts of compound ketoconazole ointments of moroxydine, 5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Embodiment 2: 40 parts of 12 parts of metronidazoles, 5 parts of 16 parts of compound ketoconazole ointments of moroxydine, 4 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Embodiment 3: 35 parts of 15 parts of metronidazoles, 3 parts of 11 parts of compound ketoconazole ointments of moroxydine, 5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Embodiment 4: 35 parts of 18 parts of metronidazoles, 3 parts of 8 parts of compound ketoconazole ointments of moroxydine, 4 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Above-mentioned medicine is commercially available, metronidazole Chifeng monumental work pharmaceutical factory forever produces, moroxydine Wanze Pharmaceutical Co., Ltd., Chifeng City produces, compound ketoconazole ointment Shanghai Fosun Zhaohui Pharmaceutical Co., Ltd. produces, health positive pharmaceutcal corporation, Ltd in lincomycin hydrochloride and lidocaine hydrochloride gel Hubei produces, and adjuvant Mel is commercially available.
Table 1 pharmaceutical composition curative effect comparision of the present invention table
| Test group | The test number | Symptom | The course of treatment | Effective percentage | Cure rate |
| With this medicine I | 100 | In just sending out 1 year | 7～30 days | 100％ | 98％ |
| With this medicine II | 112 | Morbidity 1 is to the several years | 10～40 days | 100％ | 95％ |
| Contrast | 36 | In just sending out 1 year | 7～30 days | 42％ | 20％ |
What participate in above-mentioned test group is 18～25 years old per capita, matched group metronidazole vitaminize B
6Oral, symptom is all selected morbidity people just.Oral metronidazole 0.6-1.2g/ day, divide vitamin B three times
6Oral, three times/day, each 1～2,7～10 days is a course of treatment, uses three courses of treatment.
I with medicine of the present invention organizes 100 people, the morbidity within 1 year, symptom is lighter, take effect through treating a week, three the week to around be almost recovered, have only two examples that slight recurrence is arranged.Symptom with the test II of medicine of the present invention group is heavier, generally falls ill more than 1 year, does not prolongedly heal, most of people used multiple makeup and medicine, but the just recurrence of stopping using, or just inoperative with a period of time, use medicine of the present invention, 10 days take effect, the great majority recovery from illness.
Can see that by table 1 effective percentage with medicine of the present invention, cure rate are apparently higher than contrast.
Example: Song xx, the man, 20 years old, the facial acne of giving birth to of beginning in 18 years old, forehead dough-making powder folder is more, the time heavy when light, use the ointment of much treating, all effect is bad.Morbidity is very heavy during prescription on individual diagnosis, behind nose clip ditch, the ear, breast, back have, particularly as eating maror, red and swollen heat pain.With the back further consultation of this medicine one week, acne obviously reduces, the atrophy that flattens of existing pimple, recovery from illness in 35 days, recurrence more than a year.
Claims (3)
1, a kind of pharmaceutical composition acne removing cream for the treatment of acne, it is characterized in that: it is made up of following parts of medicines by weight: 30～50 parts of 10～20 parts of metronidazoles, 3～5 parts of 5～20 parts of compound ketoconazole ointments of moroxydine, 3～5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
2, the pharmaceutical composition acne removing cream of treatment acne according to claim 1 is characterized in that: it is made up of for 30～50 parts 12～20 parts of metronidazoles, 3～5 parts of 11～20 parts of compound ketoconazole ointments of moroxydine, 3～5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
3, the pharmaceutical composition acne removing cream of treatment acne according to claim 1 is characterized in that: it is made up of for 50 parts 20 parts of metronidazoles, 20 parts of moroxydines, 5 parts of compound ketoconazole ointments, 5 parts of lincomycin hydrochloride and lidocaine hydrochloride gels and adjuvant Mel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410094860 CN1253157C (en) | 2004-11-17 | 2004-11-17 | Acne removing cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410094860 CN1253157C (en) | 2004-11-17 | 2004-11-17 | Acne removing cream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1634115A true CN1634115A (en) | 2005-07-06 |
| CN1253157C CN1253157C (en) | 2006-04-26 |
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ID=34847820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410094860 Expired - Fee Related CN1253157C (en) | 2004-11-17 | 2004-11-17 | Acne removing cream |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1253157C (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103479661A (en) * | 2013-10-21 | 2014-01-01 | 刘彩群 | Whitening, acne removal and freckle removal cosmetology medicine |
| CN104056257A (en) * | 2014-06-24 | 2014-09-24 | 谢一泓 | Emulsifiable paste for treating acne |
| CN104189061A (en) * | 2014-09-19 | 2014-12-10 | 张嗣喜 | Externally-used compound ointment for treating skin diseases and preparation method thereof |
| CN106214713A (en) * | 2016-08-15 | 2016-12-14 | 王开丽 | A kind of itching-relieving cream and preparation method thereof |
| CN113384594A (en) * | 2021-06-19 | 2021-09-14 | 李奇 | Acne-removing medicine formula and medicine preparation device thereof |
| CN115054614A (en) * | 2022-06-07 | 2022-09-16 | 付聪颖 | Facial cleansing cream for radically treating facial acne and preparation method thereof |
-
2004
- 2004-11-17 CN CN 200410094860 patent/CN1253157C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103479661A (en) * | 2013-10-21 | 2014-01-01 | 刘彩群 | Whitening, acne removal and freckle removal cosmetology medicine |
| CN104056257A (en) * | 2014-06-24 | 2014-09-24 | 谢一泓 | Emulsifiable paste for treating acne |
| CN104056257B (en) * | 2014-06-24 | 2016-01-20 | 谢一泓 | A kind of acne treatment emulsifiable paste |
| CN104189061A (en) * | 2014-09-19 | 2014-12-10 | 张嗣喜 | Externally-used compound ointment for treating skin diseases and preparation method thereof |
| CN106214713A (en) * | 2016-08-15 | 2016-12-14 | 王开丽 | A kind of itching-relieving cream and preparation method thereof |
| CN113384594A (en) * | 2021-06-19 | 2021-09-14 | 李奇 | Acne-removing medicine formula and medicine preparation device thereof |
| CN115054614A (en) * | 2022-06-07 | 2022-09-16 | 付聪颖 | Facial cleansing cream for radically treating facial acne and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1253157C (en) | 2006-04-26 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060426 Termination date: 20111117 |