CN104688808B - A kind of Whelk-eliminating paste and preparation method thereof - Google Patents
A kind of Whelk-eliminating paste and preparation method thereof Download PDFInfo
- Publication number
- CN104688808B CN104688808B CN201510147697.XA CN201510147697A CN104688808B CN 104688808 B CN104688808 B CN 104688808B CN 201510147697 A CN201510147697 A CN 201510147697A CN 104688808 B CN104688808 B CN 104688808B
- Authority
- CN
- China
- Prior art keywords
- whelk
- powder
- eliminating paste
- rifampin
- clindamycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to skin disease practical technique fields more particularly to a kind of Whelk-eliminating paste and preparation method thereof, using raw material: terbinafine hydrochloride, rifampin, clindamycin, borneol, kudzu-vine root powder, Poria cocos powder and dandelion prepare Whelk-eliminating paste.Each taste medicine compatibility comprehensive function in Whelk-eliminating paste provided by the invention, pathogenic heat, poison, wet complete treatment are thought in pathomycete, bacterium, virus and the Chinese medicine thought in doctor trained in Western medicine to whelk, curative effect is thoroughly, significantly, make such dermatosis patient such as acne, acne, whelk obtain curing rehabilitation comprehensively in a short time with low cost, restores normal life；In addition, the preparation method of Whelk-eliminating paste provided by the invention makes the curative effect of Whelk-eliminating paste be protected, and it is simple and easy to operate, production cost is low, gained ointment carries and convenient to take.
Description
Technical field
The present invention relates to skin disease practical technique fields more particularly to a kind of Whelk-eliminating paste and preparation method thereof.
Background technique
Acne, acne, whelk etc. are the common skin disease often sent out, especially whelk, and teenager is to some extent
Generally perplexed by it.There are many this kind of dermopathic inducement of acne, acne, whelk, mainly due to the leather bag of skin epidermis and
Sebaceous glands inflammation is obstructed and is caused, and specifically can be divided into fungal infection again from western medicine angle, and bacterium infection and virus infection three are big
Class.Existing anti-acne method and medicament categories are also very much, such as: laser therapy, salicylic acid, clindamycin, metronidazole, dexamethasone
Equal western medicines, the treatment of the plants essential oils such as Rosa Damascana.In above-mentioned treatment method, laser therapy cannot eradicate whelk, and
There is destruction to skin histology；Single western medicine easily makes patient generate pharmacological dependence, and side effect is larger；Plants essential oil
Therapeutic effect is good, but treatment time is long, and expensive cannot be public receiving.In addition, there are also herbal treatments, such as patent of invention
201110421645.9 disclose a kind of Whelk-eliminating paste for being applied with and using, and relationship by weight ratio is calculated as: pearl powder: land plaster:
Borneolum: Asian puccoon: rheum officinale: wheat embryo: smilax: viola japonica: lemongrass: myotonin=30:15:10:10:5:15:15:15:15:
20；For another example patent of invention 200810053192.7 discloses a kind of Whelk-eliminating paste, is made of agents, according to parts by weight, white
0.9-3.8 parts of splendid achnatherum, 1.1~4.5 parts of the root of Dahurain angelica, 0.7~4.1 part of radix scutellariae, 1~2.4 part of the flower bud of lily magnolia；These above-mentioned Chinese medicines are from " monarch drug in a prescription minister
Making " angle sets out, and achieves preferable effect in terms for the treatment of whelk, acne and this kind of skin disease of acne, and still, Chinese medicine needs
Dialectical use is only applicable to subset of patients, and treatment cycle is long.
Summary of the invention
The object of the present invention is in view of the problems of the existing technology, a kind of Whelk-eliminating paste and preparation method thereof is provided, Cuo is made
Such dermatosis patient such as sore, acne, whelk eliminates symptom with low cost in a short time, restores normal life.
The technical solution that the present invention solves the problems, such as is: a kind of Whelk-eliminating paste is provided, contains following raw material: terbinafine hydrochloride,
Rifampin, clindamycin, borneol, kudzu-vine root powder, Poria cocos powder and dandelion.
In Whelk-eliminating paste of the present invention, it is preferable that the weight of each raw material dosage is as follows: terbinafine hydrochloride 7
~40 parts, 0.03~0.3 part of rifampin, 0.1~1.2 part of clindamycin, 1~3 part of borneol, 0.1~5 part of kudzu-vine root powder, Poria cocos powder
0.1~5 part, 0.1~5 part of dandelion.
In Whelk-eliminating paste of the present invention, it is preferable that the weight of each raw material dosage is as follows: terbinafine hydrochloride 20
Part, 0.3 part of rifampin, 0.6 part of clindamycin, 2 parts of borneol, 1 part of kudzu-vine root powder, 1 part of Poria cocos powder, 1 part of dandelion.
In Whelk-eliminating paste of the present invention, it is preferable that the weight of each raw material dosage is as follows: terbinafine hydrochloride 30
Part, 0.1 part of rifampin, 1 part of clindamycin, 3 parts of borneol, 3 parts of kudzu-vine root powder, 3 parts of Poria cocos powder, 3 parts of dandelion.
In Whelk-eliminating paste of the present invention, it is preferable that the weight of each raw material dosage is as follows: terbinafine hydrochloride 7
Part, 0.03 part of rifampin, 0.1 part of clindamycin, 1 part of borneol, 0.1 part of kudzu-vine root powder, 0.1 part of Poria cocos powder, 0.1 part of dandelion.
The present invention provides the preferred preparation methods that each raw material is made to Whelk-eliminating paste of the present invention, include the following steps:
(1) terbinafine hydrochloride, rifampin, clindamycin, borneol, Pueraria lobota are weighed according to the raw material proportioning of above-mentioned Whelk-eliminating paste
Root powder, Poria cocos powder and dandelion；
(2) raw material borneol alleged by step (1) and dandelion are crushed respectively；
(3) kudzu-vine root powder alleged by step (1) and Poria cocos powder are mixed with borneol powder obtained by step (2) and dandelion part, is stirred
Uniformly；
(4) terbinafine hydrochloride alleged by step (1), rifampin and clindamycin are mixed, and stirred evenly；
(5) mixed raw material obtained by step (3) is mixed with step (4) resulting mixed raw material, is stirred evenly to get anti-acne
Cream.
Preferably, in the preparation method of Whelk-eliminating paste of the present invention, the raw material terbinafine hydrochloride is paste.
Preferably, in the preparation method of Whelk-eliminating paste of the present invention, the rifampin is built-in orange red or dark red powder
Capsule, in the step (4), when the rifampin is mixed with terbinafine hydrochloride and clindamycin, using in capsule
Powder rifampin.
Preferably, in the preparation method of Whelk-eliminating paste of the present invention, the clindamycin is solution.
Preferably, in the preparation method of Whelk-eliminating paste of the present invention, in the step (3), the kudzu-vine root powder, Poria cocos powder,
Borneol powder and dandelion powder cross 200 meshes.
Whelk-eliminating paste of the present invention and preparation method thereof is that inventor has done over one hundred experiment and formula adjustment and according to Chinese and Western medicine
Theory is developed and is obtained.The raw materials used in the present invention can be bought from market, below to the above-mentioned raw materials selected in the present invention
Be described below: raw materials used terbinafine hydrochloride, rifampin and clindamycin are Western medicine, wherein the terbinafine hydrochloride
Fungal efficacy is killed or inhibited to tool, especially effective in cure to skin problem caused by fungal infection, described when specifically selecting raw material
The preferred terbinafine hydrochloride emulsifiable paste of terbinafine hydrochloride；The rifampin is to aerobic gram positive bacteria and aerobic gram-negative bacteria
Equal multiple pathogenic microorganisms have height antibacterial activity, specific when selecting raw material, preferably rifampicin capsules；The clindamycin pair
Furuncle caused by various infection caused by gram-positive bacteria and anaerobic bacteria, carbuncle, abscess and other inflammation have therapeutic efficiency, specifically
When selecting raw material, preferably obtained by clindamycin phosphate injection；The raw materials used pungent bitter of borneol, it is slightly cold, return heart,
Spleen, lung channel have inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain effect；Raw materials used kudzu-vine root powder is smashed pueraria lobata, pueraria lobata nature and flavor are pungent, it is sweet,
It is cool, returns spleen, stomach meridian, tool relieve muscle fever and thirst, rising Yang stopping leak and promoting eruption effect；Raw materials used Poria cocos powder is smashed
Poria cocos, Poria cocos nature and flavor are sweet, light, flat, return heart, spleen, kidney channel, tool clearing damp and promoting diuresis, invigorating the spleen and tranquilizing the mind effect；Raw materials used dandelion property
It is bitter, sweet, cold, return liver, stomach meridian, the effect that has that clearing heat and detoxicating, dampness removing is treating stranguria.
Each taste medicine compatibility comprehensive function in Whelk-eliminating paste provided by the invention thinks pathogenic true to whelk in doctor trained in Western medicine
Think pathogenic heat, poison, wet complete treatment in bacterium, bacterium, virus and Chinese medicine, curative effect thoroughly, it is significant, make acne, acne, blueness
Such dermatosis patient such as spring acne obtains curing rehabilitation comprehensively in a short time with low cost, restores normal life；In addition, this hair
The preparation method of the Whelk-eliminating paste of bright offer makes the curative effect of Whelk-eliminating paste be protected, and it is simple and easy to operate, production cost is low, gained medicine
Cream carry and it is convenient to take.
Specific embodiment
Whelk-eliminating paste provided by the invention is obtained based on the research of many years Chinese and western medical and clinical experience research, screens effective medicine
Object, the over one hundred example of clinical observation have the characteristics that quick, curative effect is reliable and stable, nontoxic, without side-effects.Below by embodiment
It is specifically described.
The purpose of embodiment be illustrate Whelk-eliminating paste of the invention can made of regular dosage form, not for limiting its protection
Range or influence its disclose it is abundant.
Raw materials used and its source is as follows in following embodiments: raw material terbinafine hydrochloride passes through the hydrochloric acid of market purchasing
Terbinafine emulsifiable paste obtains, and producer is Jiangsu Fubang .Pharm Co., Ltd., and authentication code is national drug standard H20093836, and every
20g dress, every gram of 0.01g of terbinafine hydrochloride containing main component；Raw material rifampin is obtained by the rifampicin capsules of market purchasing
, producer is Shenyang Hongqi Pharmaceutical Co., Ltd., and authentication code is national drug standard H21021905, and every capsule 's content is orange
Red or dark red powder, every capsule 0.15g containing rifampin；Raw material clindamycin passes through the clindamycin phosphoric acid of market purchasing
Ester injection obtain, producer be Anhui friendship ties medicine company limited liability company, authentication code be national drug standard H20057741, every
2ml, every 0.3g containing clindamycin；Raw material borneol, kudzu-vine root powder, Poria cocos powder and dandelion are purchased by Market of Chinese Materia Medica.It needs
It is bright, in following embodiments, terbinafine hydrochloride emulsifiable paste is directly applied, carries out terbinafine hydrochloride extraction without additional；
To rifampicin capsules, using the orange red or dark red powder in its capsule；Clindamycin phosphate injection is directly applied, nothing
Need additional extractions clindamycin.
Embodiment 1
A kind of Whelk-eliminating paste of the invention, raw material (g) proportion are as follows: terbinafine hydrochloride 20g, rifampin 0.3g, clindamycin
0.6g, borneol 2g, kudzu-vine root powder 1g, Poria cocos powder 1g, dandelion 1g.
The preparation method is as follows:
(1) terbinafine hydrochloride, rifampin, clindamycin, borneol, Pueraria lobota are weighed according to the raw material proportioning of above-mentioned Whelk-eliminating paste
Root powder, Poria cocos powder and dandelion；
(2) raw material borneol alleged by step (1) and dandelion are crushed respectively；
(3) kudzu-vine root powder alleged by step (1) and Poria cocos powder are mixed with borneol powder obtained by step (2) and dandelion part, is stirred
Uniformly；
(4) terbinafine hydrochloride alleged by step (1), rifampin and clindamycin are mixed, and stirred evenly；
(5) mixed raw material obtained by step (3) is mixed with step (4) resulting mixed raw material, is stirred evenly to get anti-acne
Cream.
In the above-described embodiments, be the curative effect for ensureing last gained Whelk-eliminating paste, the kudzu-vine root powder, Poria cocos powder, borneol powder and
Dandelion powder crosses 200 meshes.
The usage of gained Whelk-eliminating paste are as follows: smeared according to patient's range, be massaged into absorption, when being at night preferred medication
Between, once a day, until symptom disappears.
Embodiment 2
A kind of Whelk-eliminating paste of the invention, raw material (g) proportion are as follows: terbinafine hydrochloride 30g, rifampin 0.1g, clindamycin
1g, borneol 3g, kudzu-vine root powder 3g, Poria cocos powder 3g, dandelion 3g.
The preparation method is the same as that of Example 1.
The usage of gained Whelk-eliminating paste is the same as embodiment 1.
Embodiment 3
A kind of Whelk-eliminating paste of the invention, raw material (g) proportion are as follows: terbinafine hydrochloride 7g, rifampin 0.03g, clindamycin
0.1g, borneol 1g, kudzu-vine root powder 0.1g, Poria cocos powder 0.1g, dandelion 0.1g.
The preparation method is the same as that of Example 1.
The usage of gained Whelk-eliminating paste is the same as embodiment 1.
Embodiment 4
A kind of Whelk-eliminating paste of the invention, raw material (g) proportion are as follows: terbinafine hydrochloride 40g, rifampin 0.3g, clindamycin
1.2g, borneol 3g, kudzu-vine root powder 5g, Poria cocos powder 5g, dandelion 5g.
The preparation method is the same as that of Example 1.
The usage of gained Whelk-eliminating paste is the same as embodiment 1.
Application experiment example
Sufficiently to show that Whelk-eliminating paste of the invention to acne, acne, this kind for the treatment of for skin disease effect of whelk, is carrying out
Before clinical application, Whelk-eliminating paste obtained by the various embodiments described above zoopery is subjected to, below to use the resulting anti-acne of embodiment 1
The zoopery that cream carries out is illustrated, but of the invention using without being limited thereto.
1, animal for research, animal origin and animal symptom are as follows:
(1) 4 common mole cricket, number is A, B, C, D respectively, and the age is respectively dog A10 months, dog B8 months, dog C12
The moon, dog D6 months, wherein have breakage in two ear of dog A, show as skin pustular eruption, pimple was showed close to human face's youth
Acne causes through chemically examining for fungi and staphy lococcus infection；Two ear inner skin of dog B shows as furuncle, has depilation at hair close to having
Phenomenon is chemically examined close to human face's acne as fungi and enterococcus, and co-infection causes；Without breakage in two ear of dog C and dog D
And infection, it is healthy normal ear；
(2) 4 common native cats, number is a, b, c, d respectively, and the age is respectively cat a10 months, cat b8 months, cat c12
The moon, cat d16 months, wherein have breakage in two ear of cat a, show as purulence born of the same parents, close to the infection phase performance of human face's whelk, chemical examination
For streptococcus and anaerobic infection；Breakage shows as redness in two ear of cat b, a small amount of dotted erythema, but does not protrude skin, through changing
Test no bacterium infection；Cat c and two ear of cat d are interior without damaged and infection, are healthy normal ear.
2, therapeutic process and method are as follows:
It will first be cleaned in each dog auricular concha of each cat with physiological saline, 1 gained Whelk-eliminating paste of the embodiment of the present invention be uniformly applied to
On each each dog auricular concha inner skin of cat, and massage promotion its absorption, wherein be comparative illustration Whelk-eliminating paste of the present invention curative effect, dog A and
Rifampin emulsifiable paste is touched in ear painting on the left of dog B, and cat a and the left side cat b ear smear clindamycin injection；The coating time is at night, to allow
It after drug acts on 12 hours on the skin, washes off, continuous use 20 days, is observed at medication daily during coating morning next day
Change of skin.
3, experimental result is as follows:
(1) Whelk-eliminating paste of the present invention to dog C, dog D, cat c and cat d ear inner skin are non-stimulated, show without phenomena such as allergy；
(2) it the right side ear of dog A and dog B Whelk-eliminating paste and is compared with the left side ear of rifampin, is existed with the right side ear of Whelk-eliminating paste
Substantially thorough rehabilitation when medication was to the 10th day, it is red and swollen there are also part when with the left side ear medication of rifampin to the 20th day and decortication is existing
As；
(3) the right side ear of cat a Whelk-eliminating paste thorough rehabilitation when medication was to the 12nd day, and existed with the left side ear of clindamycin
There are also part purulence born of the same parents and red and swollen exist when medication is to the 20th；The right side ear of cat b Whelk-eliminating paste thorough health when medication was to the 5th day
It is multiple, and with the ability rehabilitation when medication was to the 15th day of the left side ear of clindamycin.
4, conclusion: animal experiments show that, Whelk-eliminating paste of the present invention is to various fungies, the bacterium for causing skin infection by above-mentioned
It is all effective, especially there is significant curative effect to acne, acne, this kind of skin disease of whelk.
Clinical application example
Sufficiently to show Whelk-eliminating paste of the invention to acne, acne, this kind for the treatment of for skin disease effect of whelk, selection
Embodiment 1, embodiment 2, embodiment 3 and embodiment 4 is respectively adopted to patient in medical history, the state of an illness, age, the comparable patient of gender
Carry out therapeutic test, usage are as follows: once a day, Whelk-eliminating paste often is smeared inferior to affected part at night after cleaning, and be massaged into absorption,
It is cleaned then at the next morning, with 20 days as one therapeutic course；Through more than 300 example clinical observations, the surface symptoms of patient in a course for the treatment of
It completely disappears, pain and sense of discomfort also obviously disappear, and restore normal life, significant in efficacy.
It is illustrated below by way of painting with the typical case example of 1 gained Whelk-eliminating paste of embodiment, but of the invention using unlimited
In this.
Application examples 1
Selection acne, acne and whelk patient totally 100, the age 13~37 years old, wherein；Patients with acne 28, contain female
Property 20, male 8；Whelk patient 36, contain women 28, male 8；Acne patient 18, contain women 15, male
3；Acne print patient 18, contain women 15, male 3.Following therapeutic scheme is taken to this 100 patients: being made once a day
With Whelk-eliminating paste of the present invention, 1 gained Whelk-eliminating paste of the embodiment of the present invention often is smeared inferior to affected part at night after cleaning, and is massaged into suction
It receives, is cleaned then at the next morning, with 20 days as one therapeutic course, continuous use 20 days, further consultation in one week was primary.
The standard of curative effect evaluation includes: that (1) cures: clinical symptoms completely disappear, and pain and sense of discomfort completely disappear, and restore just
Often life；(2) effectively: entirely or essentially symptom is obviously eliminated, and pain and sense of discomfort obviously disappear, but there is also slight disease
Shape, only normal life is restored in part；(3) invalid: symptom is without significant change.
Clinical application experimental result is as follows:
| It cures | Effectively | In vain | It is efficient | |
| 28 people of acne | 20 | 8 | 0 | 100% |
| 36 people of whelk | 28 | 8 | 0 | 100% |
| 18 people of acne | 15 | 3 | 0 | 100% |
| 18 people of acne print | 11 | 7 | 0 | 100% |
By upper table application experiment result it is found that Whelk-eliminating paste of the present invention has acne, acne and this kind of skin disease of whelk
Significant curative effect.
In addition, also carried out a large amount of clinical comparison for the curative effect for further illustrating Whelk-eliminating paste of the present invention and tested, below with
It is illustrated for existing common rifampin cream and clindamycin and metronidazole liniment, but comparative illustration is without being limited thereto.
Control experiment example 1
Selection acne, acne and whelk patient totally 100, the age 16~33 years old, wherein；Patients with acne 35, contain female
Property 28, male 7；Whelk patient 28, contain women 20, male 8；Acne patient 25, contain women 8, male
17；Acne print patient 12, contain women 6, male 6.Following therapeutic scheme is taken to this 100 patients: being made once a day
It with rifampin cream, is often smeared inferior to affected part at night after cleaning, and is massaged into absorption, cleaned then at the next morning, with 20 days
As a treatment course, continuous use 20 days, further consultation in one week was primary.
The standard of curative effect evaluation includes: that (1) cures: clinical symptoms completely disappear, and pain and sense of discomfort completely disappear, and restore just
Often life；(2) effectively: entirely or essentially symptom is obviously eliminated, and pain and sense of discomfort obviously disappear, but there is also slight disease
Shape, only normal life is restored in part；(3) invalid: symptom is without significant change.
Experimental result is as follows:
| It cures | Effectively | In vain | It is efficient | |
| 35 people of acne | 10 | 20 | 5 | 85.7% |
| 28 people of whelk | 10 | 14 | 4 | 85.7% |
| 25 people of acne | 15 | 3 | 7 | 72% |
| 12 people of acne print | 1 | 3 | 8 | 33.3% |
The experimental result of above-mentioned rifampin cream and the clinical application experimental result of Whelk-eliminating paste of the present invention are compared it is found that the present invention
Provided Whelk-eliminating paste curative effect is more thoroughly, significantly.
Control experiment example 2
Selection acne, acne and whelk patient totally 100, the age 18~34 years old, wherein；Patients with acne 30, contain female
Property 23, male 7；Whelk patient 35, contain women 28, male 7；Acne patient 20, contain women 7, male
13；Acne print patient 15, contain women 11, male 4.Following therapeutic scheme is taken to this 100 patients: being made once a day
It with clindamycin and metronidazole liniment, is often smeared inferior to affected part at night after cleaning, and is massaged into absorption, washed then at the next morning
Only, with 20 days as one therapeutic course, continuous use 20 days, further consultation in one week was primary.
The standard of curative effect evaluation includes: that (1) cures: clinical symptoms completely disappear, and pain and sense of discomfort completely disappear, and restore just
Often life；(2) effectively: entirely or essentially symptom is obviously eliminated, and pain and sense of discomfort obviously disappear, but there is also slight disease
Shape, only normal life is restored in part；(3) invalid: symptom is without significant change.
Experimental result is as follows:
| It cures | Effectively | In vain | It is efficient | |
| 30 people of acne | 10 | 12 | 8 | 73% |
| 35 people of whelk | 12 | 13 | 0 | 71% |
| 20 people of acne | 2 | 15 | 3 | 85% |
| 15 people of acne print | 2 | 8 | 5 | 66.7% |
Compare the experimental result of above-mentioned clindamycin and metronidazole liniment and the clinical application experimental result of Whelk-eliminating paste of the present invention
It is found that Whelk-eliminating paste curative effect provided by the present invention is more thoroughly, significantly.
Generally, by above-mentioned application experiment result and contrast and experiment it is found that Whelk-eliminating paste of the present invention to acne, acne and
This kind of skin disease of whelk has significant curative effect.
Claims (9)
1. a kind of Whelk-eliminating paste, which is characterized in that the component of the Whelk-eliminating paste and weight are as follows: terbinafine hydrochloride 7~
40 parts, 0.03~0.3 part of rifampin, 0.1~1.2 part of clindamycin, 1~3 part of borneol, 0.1~5 part of kudzu-vine root powder, Poria cocos powder 0.1
~5 parts, 0.1~5 part of dandelion.
2. Whelk-eliminating paste according to claim 1, which is characterized in that the weight of each raw material dosage is as follows: salt
20 parts of sour Terbinafine, 0.3 part of rifampin, 0.6 part of clindamycin, 2 parts of borneol, 1 part of kudzu-vine root powder, 1 part of Poria cocos powder, dandelion 1
Part.
3. Whelk-eliminating paste according to claim 1, which is characterized in that the weight of each raw material dosage is as follows: salt
30 parts of sour Terbinafine, 0.1 part of rifampin, 1 part of clindamycin, 3 parts of borneol, 3 parts of kudzu-vine root powder, 3 parts of Poria cocos powder, 3 parts of dandelion.
4. Whelk-eliminating paste according to claim 1, which is characterized in that the weight of each raw material dosage is as follows: salt
7 parts of sour Terbinafine, 0.03 part of rifampin, 0.1 part of clindamycin, 1 part of borneol, 0.1 part of kudzu-vine root powder, 0.1 part of Poria cocos powder, Pu Gong
0.1 part of English.
5. a kind of preparation method of the described in any item Whelk-eliminating pastes of Claims 1-4, which comprises the steps of:
(1) according to the raw material proportioning of Whelk-eliminating paste described in any one of Claims 1-4 weigh terbinafine hydrochloride, rifampin,
Clindamycin, borneol, kudzu-vine root powder, Poria cocos powder and dandelion；
(2) raw material borneol alleged by step (1) and dandelion are crushed respectively；
(3) kudzu-vine root powder alleged by step (1) and Poria cocos powder are mixed with borneol powder obtained by step (2) and dandelion part, is stirred evenly；
(4) terbinafine hydrochloride alleged by step (1), rifampin and clindamycin are mixed, and stirred evenly；
(5) mixed raw material obtained by step (3) is mixed with step (4) resulting mixed raw material, is stirred evenly to get Whelk-eliminating paste.
6. the preparation method of Whelk-eliminating paste according to claim 5, which is characterized in that the raw material terbinafine hydrochloride is cream
Agent.
7. the preparation method of Whelk-eliminating paste according to claim 5, which is characterized in that the rifampin is built-in orange red or dark
The capsule of red powder when the rifampin is mixed with terbinafine hydrochloride and clindamycin, makes in the step (4)
With the powder rifampin in capsule.
8. the preparation method of Whelk-eliminating paste according to claim 5, which is characterized in that the clindamycin is solution.
9. the preparation method of Whelk-eliminating paste according to claim 5, which is characterized in that in the step (3), the pueraria lobata
Powder, Poria cocos powder, borneol powder and dandelion powder cross 200 meshes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510147697.XA CN104688808B (en) | 2015-03-31 | 2015-03-31 | A kind of Whelk-eliminating paste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510147697.XA CN104688808B (en) | 2015-03-31 | 2015-03-31 | A kind of Whelk-eliminating paste and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104688808A CN104688808A (en) | 2015-06-10 |
| CN104688808B true CN104688808B (en) | 2019-01-04 |
Family
ID=53336632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510147697.XA Active CN104688808B (en) | 2015-03-31 | 2015-03-31 | A kind of Whelk-eliminating paste and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104688808B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10709702B2 (en) | 2015-10-08 | 2020-07-14 | Amd Therapeutics Llc | Treatment of skin disorders by topical administration of VEGF inhibitors |
| CN105616884A (en) * | 2016-03-23 | 2016-06-01 | 古东晖 | Ointment for treating acne and preparation method of ointment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1762376A (en) * | 2004-10-19 | 2006-04-26 | 白长义 | Whitening acne-removing cream |
| CN102727795A (en) * | 2011-03-31 | 2012-10-17 | 吕维学 | Traditional Chinese medicine for treating skin diseases |
-
2015
- 2015-03-31 CN CN201510147697.XA patent/CN104688808B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1762376A (en) * | 2004-10-19 | 2006-04-26 | 白长义 | Whitening acne-removing cream |
| CN102727795A (en) * | 2011-03-31 | 2012-10-17 | 吕维学 | Traditional Chinese medicine for treating skin diseases |
Non-Patent Citations (2)
| Title |
|---|
| 中国痤疮治疗指南（2014 修订版）;中国痤疮治疗指南专家组;《临床皮肤科杂志》;20150131;第44卷(第1期);52-57页 |
| 中西医结合治疗痤疮的经验体会;可金平;《中国医疗美容》;20150228(第一期);117页 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104688808A (en) | 2015-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104784270A (en) | External preparation capable of relieving swelling and pain and preparation method thereof | |
| CN104523944A (en) | Traditional Chinese medicine for treating eczema and application thereof | |
| CN102872241A (en) | Traditional Chinese medicinal composition for treating inflammatory dermatosis and preparation thereof | |
| CN104688808B (en) | A kind of Whelk-eliminating paste and preparation method thereof | |
| CN101983652A (en) | Traditional Chinese medicine for treating scapulohumeral periarthritis | |
| CN101249184A (en) | A externally used traditional Chinese medicine preparation for treating osteoproliferation as well as its preparation method | |
| CN1281228C (en) | Medicine for hyperplasia of mammary glands and its preparation | |
| CN109847015B (en) | Traditional Chinese medicine lotion and preparation method and application thereof | |
| CN107260844A (en) | A kind of bacteriostasis spray | |
| CN115531446A (en) | Application of composition in preparing medicine for diminishing inflammation, relieving pain and healing wound | |
| CN103463570B (en) | Pharmaceutical composition and preparation method, preparation and application thereof | |
| CN102028758A (en) | Chinese medicinal herb quick-response skin moisturizer with effects of diminishing inflammation and removing acne | |
| CN101804179B (en) | Traditional Chinese medicine composition for treating hyperosteogeny of cervical vertebra and lumbar vertebra and preparation method thereof | |
| CN103239646B (en) | Chinese medicine effective part composition for treating leucoderma and preparation method thereof | |
| CN104666420A (en) | A medicine for treating rhinitis | |
| CN100389810C (en) | Medicine for eliminating acne | |
| CN104257777B (en) | Traditional Chinese medicine composition for treating rhinitis, nasosinusitis and frontal sinusitis and preparation method of traditional Chinese medicine composition | |
| CN102512650A (en) | Externally-used medicine for treating facial paralysis | |
| Shealy | The Healing Remedies Sourcebook: Over 1000 Natural Remedies to Prevent and Cure Common Ailments | |
| CN105920175A (en) | Medicinal composition for treating skin eczema and itching and preparation method thereof | |
| CN1175844C (en) | Externally-applied medicine for treaitng red swelling | |
| Chen | Herbology in Three Traditional Medicines for Acne | |
| CN105125683B (en) | A kind of pharmaceutical treatment of psoriasis and preparation method thereof | |
| CN1052156C (en) | Medicine for curing acne-"Fenciling" | |
| CN112741863A (en) | Medicine for treating skin wound and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190812 Address after: 030000 PA101-PA104 on the first floor of the South Building of Xinhe Science and Technology Park, No. 9 Xinhe Road, Taiyuan Civil Private District, Shanxi Province Patentee after: Taiyuan Fuxing Biotechnology Co., Ltd. Address before: 030013 Huilong Garden, Haojiagou Street, Yingze, Taiyuan City, Shanxi Province Patentee before: Cui Xiaolong |
|
| TR01 | Transfer of patent right |