CN104523944A - Traditional Chinese medicine for treating eczema and application thereof - Google Patents
Traditional Chinese medicine for treating eczema and application thereof Download PDFInfo
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Abstract
The invention relates to traditional Chinese medicine for treating eczema. The traditional Chinese medicine is mainly prepared from the following crude drugs of dandelions, bistort rhizome, scutellaria baicalensis, cortex phellodendri and purslane. Fructus kochiae, fructus cnidii and cortex dictamni can further be added to the traditional Chinese medicine. The invention further provides application of the traditional Chinese medicine. The traditional Chinese medicine is external medicine used for treating eczema, accords with the traditional Chinese medicine theory, and is convenient to use, and clinical tests show that the good curative effect is achieved, and erythema, skin damage, pruritus and other symptoms of patients with eczema can be remarkably relieved.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically, is a kind of Chinese medicine and application thereof for the treatment of eczema.
Background technology
Eczema be caused by multiple internal and external factor a kind ofly there is the scytitis obviously oozing out tendency, erythra multiformity, chronic phase, then limits to and invades profit and plump, and acute pruritus, easily recurs.
The pathogenic factor of eczema is very complicated, has the interaction of internal factor and extrinsic factor, is often many-sided.Extrinsic factor such as living environment climate change etc. all can affect the generation of eczema.The external world irritates as daylight, ultraviolet, cold, sweltering heat, drying, hyperhidrosis, scratches, rubs and various animal fur, plant, chemical substance etc., and some daily living article such as the cosmetics such as face cream, soap, staple fibre etc. all can bring out eczema.Some food also can make some people's eczema increase the weight of.Internal factor such as the spirit such as chronic digestive system disease, gastrointestinal dysfunction, psychentonia, insomnia, overtired, emotion changes change, and infection focus, dysbolism and endocrine function imbalance etc., all can produce or add the state of an illness of celsus' papules.From pathogeny, a kind of delayed allergy that eczema is mainly caused by the factor inside and outside complexity.Loyalty person may have certain quality, the latter arranges by inherited genetic factors, therefore occurs in specific people, but the impact of the condition such as health condition and environment of being subject to, sometimes can not to tolerate in live and work many harmless irritates, as some food can make eczema increase the weight of for such as patient.The sensitivity of patient is very strong, can to many material generation positive reactions during patch experiment; Remove some sensitizing factor, eczema pathological changes can not disappear very soon; But the patient also had makes the reactivity of body change by strengthening tempering change environment etc., then accepts the various stimulations bringing out eczema, no longer eczema can occur in the past.
At present, doctor trained in Western medicine innerlich anwenden Therapeutic Method, first-selected antihistaminic, multiselect two kinds of use in conjunction.Medicine for external use Therapeutic Method, acute eczema is red and swollen obviously, have and ooze out in a large number, or has the skin lesion of erosion, ulceration, should use cold wet compress, commonly use the boric acid solution of 3%.Red and swollen not serious, can external zinc oil when vesicle, sepage are few; Have during infection and can use ethacridine zinc oxid oil.Mild redness, pimple, vesicle and without sepage, petty rotten time can with forging Calamine Lotion.Subacute stage can select glucocorticoid Emulsion, paste; For preventing and controlling secondary infection, antibacterials can be added.Chronic phase, can select ointment, plaster, liniment; Intractable limitation skin lesion Useful corticosteroids does injection in skin lesion.The multiplex chemistry of this type of disease of western medical treatment or hormone medicine, have toxic and side effects and easily produce drug resistance.
Chinese patent literature CN104138545A discloses a kind of medicine being used for the treatment of eczema, is prepared from by the Radix Rehmanniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba, stiff Cicadae, Radix Saposhnikoviae, Cortex Dictamni, Periostracum Cicadae, Yellow cypress, Rhizoma Alismatis, Semen Plantaginis, raw pearl barley, Poria, Talcum, Medulla Tetrapanacis, the Rhizoma Atractylodis Macrocephalae.Chinese patent literature CN104116816A discloses a kind of External apply medicinal wine for the treatment of eczema, and it is made up of the raw material of following weight portion: Fructus Cnidii 120 ~ 130 grams, Radix Sophorae Flavescentis 110 ~ 115 grams, Cortex Dictamni 55 ~ 65 grams, Radix Saposhnikoviae 70 ~ 75 grams, 55 ~ 65 grams, Alumen, the Fructus Kochiae 60 ~ 65 Ke, Herba Siegesbeckiae 115 ~ 125 grams, Fructus Xanthii 45 ~ 55 grams, Galla Chinensis 55 ~ 65 grams, 60 degree of Chinese liquor 2.5 ~ 2.9 kilograms.Chinese patent literature CN103100076A discloses a kind of medicament for the treatment of eczema, be made up of the material of following weight proportioning: Radix Scrophulariae 5-10 part, Rhizoma Zingiberis 10-20 part, Fructus Corni 20-30 part, Radix Platycodonis 10-20 part, Radix Angelicae Dahuricae 15-25 part, Flos Inulae 5-15 part, Herba Portulacae 10-30 part, Herba Aristolochiae 1-15 part, Radix Saposhnikoviae 10-20 part, Concha Arcae 15-30 part, Fructus Terminaliae Billericae 20-30 part, Radix Morindae Officinalis 1-20 part, Herba Scutellariae Barbatae 1-20 part, Rhizoma Imperatae 10-25 part, Fructus Xanthii 10-30 part, Fructus Phyllanthi 1-20 part, Indigo Naturalis 15-20 part, Fructus Amomi Rotundus 10-20 part, Herba Inulae 15-20 part, Herba Sarcandrae 15-30 part, Herba Clinopodii 10-20 part, Semen Melo 10-25 part, Spora Lygodii 5-15 part, Herba Ecliptae 1-20 part, Folium Rhododendri Daurici 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 10-20 part, Herba Glechomae 10-30 part, Concha Ostreae 1-15 part, Periostracum Serpentis 15-20 part and Semen Nelumbinis 5-15 part.But about of the present invention a kind of treat eczema Chinese medicine and application yet there are no report.
Summary of the invention
The object of the invention is for deficiency of the prior art, a kind of Chinese medicine for the treatment of eczema is provided.
Of the present invention again one object be that a kind of application for the treatment of the Chinese medicine of eczema is provided.
For achieving the above object, the technical scheme that the present invention takes is: a kind of Chinese medicine for the treatment of eczema, and described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part.
Described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part.
Described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts.
Described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part, Fructus Kochiae 5-15 part, Fructus Cnidii 5-15 part, Cortex Dictamni 5-15 part.
Described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part, Fructus Kochiae 8-12 part, Fructus Cnidii 8-12 part, Cortex Dictamni 8-12 part.
Described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts, the Fructus Kochiae 10 parts, Fructus Cnidii 10 parts, Cortex Dictamni 10 parts.
For realizing above-mentioned second object, the technical scheme that the present invention takes is: the application of described Chinese medicine in the medicine of preparation treatment eczema.
Described eczema is acute, subacute or chronic eczema.
Described pharmaceutical dosage form is tincture, spirit, powder, lotion, oil preparation, Emulsion, ointment, paste, plaster, liniment, gel, aerosol or Babu cream.
The invention has the advantages that:
Chinese medicine of the present invention is the medicine for external use being used for the treatment of eczema, meets Chinese medical theory, easy to use, and clinical trial shows, and possesses good curative effect, can significantly improve the symptoms such as eczema patients erythema, skin lesion and pruritus.
Detailed description of the invention
Below in conjunction with embodiment, detailed description of the invention provided by the invention is elaborated.
Treat a Chinese medicine for eczema, described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part.Preferably, Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part.
Treat a Chinese medicine for eczema, described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part, Fructus Kochiae 5-15 part, Fructus Cnidii 5-15 part, Cortex Dictamni 5-15 part.Preferably, Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part, Fructus Kochiae 8-12 part, Fructus Cnidii 8-12 part, Cortex Dictamni 8-12 part.
Embodiment 1 Chinese medicine one
Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts.
Embodiment 2 Chinese medicine one
Herba Taraxaci 12 parts, Rhizoma Bistortae 12 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 5 parts, Herba Portulacae 22 parts.
Embodiment 3 Chinese medicine one
Herba Taraxaci 8 parts, Rhizoma Bistortae 8 parts, Radix Scutellariae 12 parts, Cortex Phellodendri 7 parts, Herba Portulacae 18 parts.
Embodiment 4 Chinese medicine one
Herba Taraxaci 5 parts, Rhizoma Bistortae 15 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 8 parts, Herba Portulacae 25 parts.
Embodiment 5 Chinese medicine one
Herba Taraxaci 15 parts, Rhizoma Bistortae 5 parts, Radix Scutellariae 15 parts, Cortex Phellodendri 4 parts, Herba Portulacae 15 parts.
The preparation of embodiment 6 Chinese medicine one
The pharmaceutical dosage form that the arbitrary described Chinese medicine of embodiment 1-5 is prepared by conventional formulation means, such as washout decoction, tincture, spirit, powder, lotion, oil preparation, Emulsion, ointment, paste, plaster, liniment, gel, aerosol or Babu cream.
Embodiment 7 Chinese medicine two
Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts, the Fructus Kochiae 10 parts, Fructus Cnidii 10 parts, Cortex Dictamni 10 parts.
Embodiment 8 Chinese medicine two
Herba Taraxaci 8 parts, Rhizoma Bistortae 12 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 7 parts, Herba Portulacae 18 parts, the Fructus Kochiae 8 parts, Fructus Cnidii 12 parts, Cortex Dictamni 8 parts.
Embodiment 9 Chinese medicine two
Herba Taraxaci 12 parts, Rhizoma Bistortae 8 parts, Radix Scutellariae 12 parts, Cortex Phellodendri 5 parts, Herba Portulacae 22 parts, the Fructus Kochiae 12 parts, Fructus Cnidii 8 parts, Cortex Dictamni 12 parts.
Embodiment 10 Chinese medicine two
Herba Taraxaci 5 parts, Rhizoma Bistortae 15 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 8 parts, Herba Portulacae 15 parts, the Fructus Kochiae 15 parts, Fructus Cnidii 5 parts, Cortex Dictamni 15 parts.
Embodiment 11 Chinese medicine two
Herba Taraxaci 15 parts, Rhizoma Bistortae 5 parts, Radix Scutellariae 15 parts, Cortex Phellodendri 4 parts, Herba Portulacae 25 parts, the Fructus Kochiae 5 parts, Fructus Cnidii 15 parts, Cortex Dictamni 5 parts.
The preparation of embodiment 12 Chinese medicine two
The pharmaceutical dosage form that the arbitrary described Chinese medicine of embodiment 7-11 is prepared by conventional formulation means, such as washout decoction, tincture, spirit, powder, lotion, oil preparation, Emulsion, ointment, paste, plaster, liniment, gel, aerosol or Babu cream.
Embodiment 13 clinical trial
1. physical data
All cases are Changhai hospital outpatient patient in year August in August, 2012 to 2014, totally 150 examples, age 19-72 year, average 49.8 years old.Patient is divided at random matched group, treatment group one and treatment group two, each 50 examples of matched group, treatment group one and treatment group two.In matched group, acute eczema 5 example, subacute eczema 17 example, chronic eczema 28 example.In treatment group one, acute eczema 5 example, subacute eczema 18 example, chronic eczema 27 example.In treatment group two, acute eczema 5 example, subacute eczema 16 example, chronic eczema 29 example.All not statistically significants (P > 0.05) such as three groups of sexes, age differencess etc., have comparability.
2. Therapeutic Method
Matched group: give emulsion of hydrocortisone butyrate, every day puts on the skin outward for each 1 time sooner or later, 2 weeks courses for the treatment of.
Treatment group one: the washout decoction of the Chinese drug preparation of embodiment 1, every day is each 1 washout sooner or later, 2 weeks courses for the treatment of.
Treatment group two: the washout decoction of the Chinese drug preparation of embodiment 7, every day is each 1 washout sooner or later, 2 weeks courses for the treatment of.
3. curative effect determinate standard
Cure, skin lesion disappears completely, and gargalesthesia disappears, therapeutic index >=95%; Effectively obviously disappear for skin lesion, scratchiness obviously alleviates, therapeutic index 60% ~ 95%; Effectively, skin lesion disappears to some extent, and gargalesthesia alleviates to some extent, therapeutic index 20% ~ 60%; Invalid, skin lesion disappears less or unchanged, gargalesthesia with before treatment or aggravation, therapeutic index≤20%.Obvious effective rate is that healing adds effective meter.Wherein, total mark × 100% before therapeutic index=(before treatment the rear total mark of total mark-treatment)/treatment, standards of grading are as shown in table 1.
The standards of grading of table 1 dermatitis and eczema
1.4 statistical method
Adopt SPSS10.0 software, carry out X 2 test, P < 0.05 has statistical significance for difference.
1.5 therapeutic outcome
After treatment, the symptom of matched group, treatment group one and treatment group two makes moderate progress before all comparatively treating, P < 0.05; The curative effect for the treatment of group one, treatment group two is obviously better than matched group, P < 0.05.In therapeutic process, allly meet subject patient and have no obvious adverse reaction.Concrete therapeutic outcome is as shown in table 2, table 3.
Before and after the treatment of three groups, table 2, symptom integral compares
Table 3 three groups of comparitive study
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be considered as protection scope of the present invention.
Claims (9)
1. treat a Chinese medicine for eczema, it is characterized in that, described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part.
2. Chinese medicine according to claim 1, is characterized in that, described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part.
3. Chinese medicine according to claim 1, is characterized in that, described Chinese medicine is made up of the crude drug comprising following weight portion: Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts.
4. Chinese medicine according to claim 1, it is characterized in that, described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 5-15 part, Rhizoma Bistortae 5-15 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 4-8 part, Herba Portulacae 15-25 part, Fructus Kochiae 5-15 part, Fructus Cnidii 5-15 part, Cortex Dictamni 5-15 part.
5. Chinese medicine according to claim 1, it is characterized in that, described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 8-12 part, Rhizoma Bistortae 8-12 part, Radix Scutellariae 8-12 part, Cortex Phellodendri 5-7 part, Herba Portulacae 18-22 part, Fructus Kochiae 8-12 part, Fructus Cnidii 8-12 part, Cortex Dictamni 8-12 part.
6. Chinese medicine according to claim 1, it is characterized in that, described Chinese medicine is made up of the crude drug of following weight portion: Herba Taraxaci 10 parts, Rhizoma Bistortae 10 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 6 parts, Herba Portulacae 20 parts, the Fructus Kochiae 10 parts, Fructus Cnidii 10 parts, Cortex Dictamni 10 parts.
7. according to the application of the arbitrary described Chinese medicine of claim 1-6 in the medicine of preparation treatment eczema.
8. application according to claim 7, is characterized in that, described eczema is acute, subacute or chronic eczema.
9. application according to claim 7, is characterized in that, described pharmaceutical dosage form is tincture, spirit, powder, lotion, oil preparation, Emulsion, ointment, paste, plaster, liniment, gel, aerosol or Babu cream.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105031172A (en) * | 2015-08-28 | 2015-11-11 | 青岛海之源智能技术有限公司 | Paste used for treating stasis dermatitis and preparation method thereof |
| CN105727035A (en) * | 2016-03-31 | 2016-07-06 | 广州暨南生物医药研究开发基地有限公司 | Traditional Chinese medicine composition containing folium artemisiae argyi for treating erythema nodosum and preparation method of traditional Chinese medicine composition |
| CN105748757A (en) * | 2015-10-12 | 2016-07-13 | 烟台市蓝洋之草医药生物科技有限公司 | Method for preparing traditional Chinese medicine liniment for treating itch of skin |
| CN105796807A (en) * | 2016-04-29 | 2016-07-27 | 欧卉 | Externally-applied medicine capable of treating acute eczema |
| CN106109697A (en) * | 2016-06-24 | 2016-11-16 | 赵晶晶 | A kind of herbal mixture unguentum treating childhood eczema and preparation method |
| CN106421087A (en) * | 2016-04-24 | 2017-02-22 | 青岛辰达生物科技有限公司 | Pharmaceutical preparation for treating acute eczema, and use of pharmaceutical preparation |
| CN107617010A (en) * | 2017-05-04 | 2018-01-23 | 常州桐树生物科技有限公司 | A kind of Chinese medicine composition of external curing fash and its preparation method and application |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031172A (en) * | 2015-08-28 | 2015-11-11 | 青岛海之源智能技术有限公司 | Paste used for treating stasis dermatitis and preparation method thereof |
| CN105748757A (en) * | 2015-10-12 | 2016-07-13 | 烟台市蓝洋之草医药生物科技有限公司 | Method for preparing traditional Chinese medicine liniment for treating itch of skin |
| CN105727035A (en) * | 2016-03-31 | 2016-07-06 | 广州暨南生物医药研究开发基地有限公司 | Traditional Chinese medicine composition containing folium artemisiae argyi for treating erythema nodosum and preparation method of traditional Chinese medicine composition |
| CN106421087A (en) * | 2016-04-24 | 2017-02-22 | 青岛辰达生物科技有限公司 | Pharmaceutical preparation for treating acute eczema, and use of pharmaceutical preparation |
| CN105796807A (en) * | 2016-04-29 | 2016-07-27 | 欧卉 | Externally-applied medicine capable of treating acute eczema |
| CN106109697A (en) * | 2016-06-24 | 2016-11-16 | 赵晶晶 | A kind of herbal mixture unguentum treating childhood eczema and preparation method |
| CN107617010A (en) * | 2017-05-04 | 2018-01-23 | 常州桐树生物科技有限公司 | A kind of Chinese medicine composition of external curing fash and its preparation method and application |
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