CN105412358A - Chinese herbal preparation for preventing and controlling cattle and sheep skin mucosa blistering necrotic disease - Google Patents

Chinese herbal preparation for preventing and controlling cattle and sheep skin mucosa blistering necrotic disease Download PDF

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Publication number
CN105412358A
CN105412358A CN201510944726.5A CN201510944726A CN105412358A CN 105412358 A CN105412358 A CN 105412358A CN 201510944726 A CN201510944726 A CN 201510944726A CN 105412358 A CN105412358 A CN 105412358A
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China
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parts
sheep
chinese medicine
medicine preparation
cattle
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Chinese (zh)
Inventor
李云岗
张栋
杨林
张荣芳
张洪杰
徐淑华
刘波
刘娜
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SHANDONG ANIMAL EPIDEMIC DISEASE PREVENTION AND CONTROL CENTER
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SHANDONG ANIMAL EPIDEMIC DISEASE PREVENTION AND CONTROL CENTER
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Priority to CN201510944726.5A priority Critical patent/CN105412358A/en
Publication of CN105412358A publication Critical patent/CN105412358A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a Chinese herbal preparation for preventing and controlling cattle and sheep skin mucosa blistering necrotic disease. The Chinese herbal preparation is prepared from the following components in parts by weight: 80-120 parts of honeysuckle, 80-120 parts of fructus forsythiae, 80-120 parts of scutellaria baicalensis, 80-120 parts of coptis chinensis, 80-120 parts of cortex phellodendri, 80-120 parts of dried radix rehmanniae, 80-120 parts of radix scrophulariae, 40-60 parts of radix bupleuri, 40-60 parts of cape jasmine, 40-60 parts of cortex lycii radicis, 40-60 parts of potentilla discolor and 40-60 parts of liquorice. The Chinese herbal preparation is simple to prepare, easy for raw material acquisition, exact in effect, free of side effects and drug residues, can improve the resistance and immunity of cattle and sheep organism, and can ensure healthy breeding of cattle and sheep.

Description

A kind of Chinese medicine preparation for preventing and treating cattle and sheep mucocutaneous bleb necrosis disease
Technical field
The present invention relates to a kind of Chinese medicine preparation for preventing and treating cattle and sheep mucocutaneous bleb necrosis disease, belonging to Chinese herbal and crude drugs preparations and application thereof.
Background technology
Cattle and sheep mucocutaneous bleb necrosis disease is the serious class disease of harm cattle, sheep comparision of production, it not only may cause the death of large quantities of cattle, sheep, cause economic loss, and the infectious disease of some infecting both domestic animals and human brings serious threat can also to the health of people, especially sheep PPR is seriously popular, case fatality rate is high, brings greater loss to sheep husbandry.In recent years, modern livestock breeding industry and scientific research need, and raising high concentration, the allocation and transportation of cattle, sheep are frequent, are more vulnerable to the invasion and attack of infectious disease.Therefore actively carry out the preventing and controlling of cattle and sheep mucocutaneous bleb necrosis disease, development cattle and sheep are produced and ensures that human health tool is of great significance.
At present, for cattle and sheep mucocutaneous bleb necrosis disease not certain effectively preventing method, the method for immunity inoculation or injection of antibiotics is usually adopted to prevent this type of disease.When the early symptom of mucocutaneous bleb necrosis disease appears in cattle and sheep, often take the measure isolated, sterilize to guarantee that healthy cattle and sheep are not infected, the mode simultaneously giving ill cattle and sheep injection of antibiotics reduces the occurrence probability of cattle and sheep secondary infection and complication.But this processing mode has serious destruction to cattle and sheep rumen microorganism flora, and antibiotics residues affects livestock product safety, also drug resistance can be increased simultaneously.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for preventing and treating cattle and sheep mucocutaneous bleb necrosis disease.The present invention is simple for the Chinese medicine preparation preparation preventing and treating cattle and sheep mucocutaneous bleb necrosis disease, raw material is easily got, definite effect, have no side effect, drug residue free, resistance and the immunity of cattle and sheep body can be improved, ensure the healthy aquaculture of cattle and sheep.
Chinese medicine preparation for preventing and treating cattle and sheep mucocutaneous bleb necrosis disease provided by the invention, be made up of the component of following parts by weight:
Flos Lonicerae 80 ~ 120 parts; Fructus Forsythiae 80 ~ 120 parts; Radix Scutellariae 80 ~ 120 parts; Rhizoma Coptidis 80 ~ 120 parts; Cortex Phellodendri 80 ~ 120 parts; 80 ~ 120 parts, the Radix Rehmanniae; Radix Scrophulariae 80 ~ 120 parts; Radix Bupleuri 40 ~ 60 parts; Fructus Gardeniae 40 ~ 60 parts; Cortex Lycii 40 ~ 60 parts; Herba Potentillae Discoloris 40 ~ 60 parts; 40 ~ 60 parts, Radix Glycyrrhizae.
In above-mentioned Chinese medicine preparation, described Chinese medicine preparation is made up of the component of following parts by weight:
Described Flos Lonicerae 100 parts; Described Fructus Forsythiae 100 parts; Described Radix Scutellariae 100 parts; Described Rhizoma Coptidis 100 parts; Described Cortex Phellodendri 100 parts; 100 parts, the described Radix Rehmanniae; Described Radix Scrophulariae 100 parts; Described Radix Bupleuri 50 parts; Described Fructus Gardeniae 50 parts; Described Cortex Lycii 50 parts; Described Herba Potentillae Discoloris 50 parts; 50 parts, described Radix Glycyrrhizae.
In above-mentioned Chinese medicine preparation, the dosage form of described Chinese medicine preparation is powder and/or oral liquid.
Present invention also offers the preparation method of above-mentioned Chinese medicine preparation, the method (1) that employing comprises the steps or (2) are made:
(1) powder of described component is mixed to get.
(2) described component is soaked in water, then decoct in described water, get decoction liquor, described decoction liquor is made described oral liquid, namely obtain described Chinese medicine preparation.
In the present invention, when the dosage form of described Chinese medicine preparation is powder, described Chinese medicine preparation is (1) preparation according to the method described above, specifically described component drying is then ground into powder and mixes;
When the dosage form of described Chinese medicine preparation is powder, its using method is as follows: cattle, 100g/ days; Sheep, 50g/ days; Every day feeds at twice, is used in conjunction 4 ~ 5 days.Healthy group's centralization-breeding factory often daily feeding for twice prevents cattle and sheep mucocutaneous bleb necrosis disease;
When the dosage form of described Chinese medicine preparation is oral liquid, described Chinese medicine preparation is (2) preparation according to the method described above;
When the dosage form of described Chinese medicine preparation is oral liquid, concrete preparation method is as follows: the weight portion taking each component, adds 500 ml waters and does not have, and soaks after 1 hour and starts to decoct, continue decoction 20 minutes, pour out medicinal liquid about 300 milliliters after boiling; And then add water 500 milliliters, continue to decoct, decoct 30 minutes after boiling, pour out medicinal liquid about 200 milliliters; The medicinal liquid taken twice mixes, and obtains the Chinese medicine oral liquid of preventing and treating cattle and sheep mucocutaneous bleb necrosis disease by every bottle of 500 milliliters of metering packings.
In the present invention, when the dosage form of described Chinese medicine preparation is oral liquid, its using method is as follows: cattle, 500ml/ days; Sheep, 250ml/ days, every natural gift are fed for two to three times, are used in conjunction 4 ~ 5 days.Healthy group's centralization-breeding factory often daily feeding for twice prevents cattle and sheep mucocutaneous bleb necrosis disease.
Present invention also offers the application of above-mentioned Chinese medicine preparation in the medicine of preparation treatment cattle and sheep mucocutaneous bleb necrosis disease.
In above-mentioned application, described cattle and sheep mucocutaneous inflammation bleb necrosis disease is sheep infective pustule, sore mouth virus, sheep infective keratitis and/or bovine viral diarrhoea-mucosal disease.
Invention further provides a kind of medicine, the active component of this medicine is described Chinese medicine preparation.
The present invention has the following advantages:
1, the present invention is a kind of medicine of environmental protection, has health care, prevents and cures diseases, growth promoting effects, drug residue free and the feature do not developed immunity to drugs.
2, Chinese medicine preparation of the present invention adopts the comprehensive synergism of 12 taste crude drug can improve immunity and the resistance of cattle and sheep body, to reach the object of prevention and therapy cattle and sheep mucocutaneous bleb necrosis disease.
3, there is preparation method easy, feature evident in efficacy; To the cattle and sheep through therapy rehabilitation, late growing stage impact is little, and without situation about recurring; Be specially adapted to the preventive and therapeutic action of cattle and sheep mucocutaneous bleb necrosis disease.
4, in formula of the present invention, each composition medicine medicine source is enriched, and low price, preparation cost is low.
Detailed description of the invention
The experimental technique used in following embodiment if no special instructions, is conventional method.
Material used in following embodiment, reagent etc., if no special instructions, all can obtain from commercial channels.
Embodiment 1, for preventing and treating the Chinese medicine preparation of cattle and sheep mucocutaneous bleb necrosis disease
According to the weight portion of following each prescription medicine take raw material (unit: g):
1, the preparation method of powder:
Take each raw material according to the weight portion of above-mentioned each component, be ground into Powdered after dry mixed, obtain by every bag of 500 grams of metering packings the Chinese medicine preparation powder preventing and treating cattle and sheep mucocutaneous bleb necrosis disease.
2, the preparation method of oral liquid:
Take each raw material according to the weight portion of above-mentioned each component, add 500 ml waters and do not have Chinese medicine, soak after 1 hour and start to decoct, continue decoction after boiling 20 minutes, pour out medicinal liquid about 300 milliliters.And then add water 500 milliliters, continue to decoct, decoct 30 minutes after boiling, pour out medicinal liquid about 200 milliliters.The medicinal liquid taken for twice mixes, and obtains by the metering packings of 500 milliliters every bottle the Chinese medicine preparation oral liquid preventing and treating cattle and sheep mucocutaneous bleb necrosis disease.
3, usage and consumption:
Powder: cattle: 100g/ days, sheep: 50g/ days, every day feeds at twice, is used in conjunction 4-5 days.Please follow the doctor's advice.Often daily twice prevention of healthy group's centralization-breeding factory.
Oral liquid: cattle: 500ml/ days, sheep: 250ml/ days, every natural gift are fed for two to three times, are used in conjunction 4-5 days.Please follow the doctor's advice.Often daily twice prevention of healthy group's centralization-breeding factory.
One, in order to verify the curative effect of the present invention to treatment cattle and sheep mucocutaneous bleb necrosis disease, the ill sheep of boil on the nape opposite the mouth of the present invention, ulcer of lip, incrustation only adopts the therapeutic scheme of distinct methods to carry out tracing observation experiment, experiment point treatment group and matched group totally four groups, often organize 10, totally 40 ill sheep are only tested, as shown in table 1 through sorting-out in statistics therapeutic outcome of the present invention data.
The experiment grouping of table 1 different treatment methods and cure rate
As shown in Table 1:
1, the powder of Chinese medicine preparation of the present invention or oral liquid treatment effect obviously will be better than Western medicine group (group 3) and matched group (organizing 4);
2, the experimental group 1 in his-and-hers watches 1, group 2 cures 10 sheep of rehabilitation, carries out finding its tracing observation, and the sheep after healing is only healthy normal, and the state of an illness, without repeatedly, illustrates the powder of Chinese medicine preparation of the present invention or the effective of oral liquid.
Two, in order to verify the curative effect of the present invention to treatment cattle and sheep mucocutaneous bleb necrosis disease, Chinese medicine preparation powder of the present invention is adopted to carry out the experiment of distinct methods treatment tracing observation with oral liquid to 50 ill sheep (not being separated with flock of sheep) respectively:
1, case definition: sick sheep body temperature raises, appetite reduces, and ulcer appears in the positions such as mouth, lip, gingival mucosa, and with symptom of diarrhea.
2, efficacy assessment standard:
Cure: medication 1-2 days, ulcer, symptom of diarrhea disappear, and body temperature, appetite are normal.
Effective: medication 2-3 days, the healing of ulcer place is very fast, and occur diarrhoea once in a while, body temperature, appetite are normal.
Effective: medication 3-5 days, ulcer place starts to take a turn for the better, and suffer from diarrhoea once in a while, body temperature declines gradually, and appetite starts to increase.
Invalid: before and after treatment, symptom, sign are without significant change.
3, to 50 ill sheep only and the sheep of the flock of sheep be not separated with 50 ill sheep, all feed according to above-mentioned usage and consumption, as shown in table 2 through its therapeutic outcome data of sorting-out in statistics.
The total effective rate of table 2 Chinese medicine preparation powder of the present invention and oral liquid treatment
As shown in Table 2, Chinese medicine preparation of the present invention cures 97 sheep of rehabilitation, carries out finding its tracing observation, and the sheep after healing is only healthy normal, and the state of an illness is without repeatedly, and prove that the therapeutic effect of the powder of Chinese medicine preparation of the present invention or oral liquid is good, the situation is more stablized.
In addition, the sheep in the flock of sheep be not separated with 50 ill sheep is susceptible flock of sheep, not ill through medication, proves that the powder of Chinese medicine preparation of the present invention or oral liquid have preventive effect.
Three, by clinical concrete model case test, further checking is done to treatment curative effect of the present invention:
Clinical model case 1 is tested:
Poultry is main: Liu so-and-so
Sheep about body weight 35Kg, on August 21st, 2015, ill sheep body temperature raises, 41.5 DEG C, and spirit is depressed, and appetite is given up absolutely, ruminate number of times reduces, and with symptom of diarrhea.According to usage and dosage of the present invention, take above-mentioned Chinese medicine preparation oral liquid 4 days.Further consultation after medication, sheep temperature decline to normal level, without diarrhoea phenomenon.Spirit takes a turn for the better, appetite and ruminate number of times and increase gradually, and the state of an illness is cured.
Clinical model case 2 is tested:
Poultry is main: Yang
The main raising boer goat of this poultry 52, about body weight 45Kg.On JIUYUE 8th, 2015, a sheep mouth, lip, gums cash out the phenomenon of redness, ulcer, and serious sheep only occurs sialorrhea, form a scab in ulcer place.Sick sheep down in spirits, appetite and feed intake decline.According to usage and dosage of the present invention, jumpbogroup Chinese medicine preparation powder of the present invention carries out spice control, is used in conjunction 4 days; The sheep be in a bad way only carries out Chinese medicine preparation oral liquid of the present invention and gavages, and is used in conjunction 4 days.Pay a return visit after four days, a jumpbogroup sheep state of an illness takes a turn for the better, and without mouth, lip, gumboil phenomenon, serious sheep lip only goes out incrustation to start to come off.Flock of sheep spirit takes a turn for the better, and feed intake increases gradually.
Clinical model case 3 is tested:
Poultry is main: king so-and-so
Beef cattle about 500Kg, on JIUYUE 28th, 2015, this cattle occurs that body temperature raises, 41.2 DEG C, and spirit is poor, eye episcleral redness, cutis laxa, and with symptom of diarrhea.According to usage and dosage of the present invention, in forage, admix Chinese medicine preparation powder of the present invention, be used in conjunction 3 days, and gavage Chinese medicine preparation oral liquid of the present invention and be used in conjunction 3 days.Pay a return visit after three days, this Niu Tiwen has been down to normal body temperature (38.6 DEG C), and spirit takes a turn for the better, and appetite strengthens, and symptom of diarrhea disappears.
By above-mentioned 3 clinical concrete model case tests, prove that the present invention is for preventing and treating the treatment good effect of the Chinese medicine preparation of cattle and sheep mucocutaneous bleb necrosis disease, has no side effect, and without recurrence.

Claims (7)

1. for preventing and treating a Chinese medicine preparation for cattle and sheep mucocutaneous bleb necrosis disease, it is characterized in that: this Chinese medicine preparation is made up of the component of following parts by weight:
Flos Lonicerae 80 ~ 120 parts; Fructus Forsythiae 80 ~ 120 parts; Radix Scutellariae 80 ~ 120 parts; Rhizoma Coptidis 80 ~ 120 parts; Cortex Phellodendri 80 ~ 120 parts; 80 ~ 120 parts, the Radix Rehmanniae; Radix Scrophulariae 80 ~ 120 parts; Radix Bupleuri 40 ~ 60 parts; Fructus Gardeniae 40 ~ 60 parts; Cortex Lycii 40 ~ 60 parts; Herba Potentillae Discoloris 40 ~ 60 parts; 40 ~ 60 parts, Radix Glycyrrhizae.
2. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the component of following parts by weight:
Described Flos Lonicerae 100 parts; Described Fructus Forsythiae 100 parts; Described Radix Scutellariae 100 parts; Described Rhizoma Coptidis 100 parts; Described Cortex Phellodendri 100 parts; 100 parts, the described Radix Rehmanniae; Described Radix Scrophulariae 100 parts; Described Radix Bupleuri 50 parts; Described Fructus Gardeniae 50 parts; Described Cortex Lycii 50 parts; Described Herba Potentillae Discoloris 50 parts; 50 parts, described Radix Glycyrrhizae.
3. Chinese medicine preparation according to claim 1 and 2, is characterized in that: the dosage form of described Chinese medicine preparation is powder and/or oral liquid.
4. the preparation method of the Chinese medicine preparation according to any one of claim 1-3, the method (1) that employing comprises the steps or (2) are made:
(1) powder of described component is mixed to get.
(2) described component is soaked in water, then decoct in described water, get decoction liquor, described decoction liquor is made described oral liquid, namely obtain described Chinese medicine preparation.
5. the application of the Chinese medicine preparation according to any one of claim 1-3 in the medicine of preparation treatment cattle and sheep mucocutaneous bleb necrosis disease.
6. application according to claim 5, is characterized in that: described cattle and sheep mucocutaneous inflammation bleb necrosis disease is sheep infective pustule, sore mouth virus, sheep infective keratitis and/or bovine viral diarrhoea-mucosal disease.
7. a medicine, is characterized in that: the Chinese medicine preparation of active component according to any one of claim 1-3 of this medicine.
CN201510944726.5A 2015-12-16 2015-12-16 Chinese herbal preparation for preventing and controlling cattle and sheep skin mucosa blistering necrotic disease Pending CN105412358A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106359952A (en) * 2016-11-30 2017-02-01 刘吴阳 Feed additive for goat pox disease
CN108403825A (en) * 2018-06-06 2018-08-17 河南三木绿源畜牧养殖有限公司 A kind of middle drug and preparation method thereof for treating sore mouth virus

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CN1907372A (en) * 2006-08-09 2007-02-07 张玉柱 Medicine for treating epidemic diseases of domestic birds and animals
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