CN105267800A - Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry - Google Patents
Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry Download PDFInfo
- Publication number
- CN105267800A CN105267800A CN201510797476.7A CN201510797476A CN105267800A CN 105267800 A CN105267800 A CN 105267800A CN 201510797476 A CN201510797476 A CN 201510797476A CN 105267800 A CN105267800 A CN 105267800A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- medicine
- chinese medicine
- poultry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry. By the aid of the traditional Chinese medicine ointment, problems that fungal skin diseases cannot be thoroughly radically treated, medicine-resistant strains can be generated and toxic and side effects can be realized in the prior art can be effectively solved. The technical scheme includes that the traditional Chinese medicine ointment comprises, by weight, 15-30 g of traditional Chinese medicine extract, 8-15 g of stearic acid, 2-5 g of glyceryl monostearate, 2-5 g of liquid paraffin, 2-4 g of Vaseline, 2-5 g of lanolin, 0.5-1 g of triethanolamine, 0.2 g of ethylparaben, 10-20 g of urea and 30-60 mL of distilled water; the traditional Chinese medicine extract comprises, by weight, 50-100 parts of fructus cnidii, 50-100 parts of radix sophorae flavescentis, 10-50 parts of Szechwan chinaberry fruits, 10-50 parts of cortex dictamni, 10-50 parts of ligusticum wallichii, 10-50 parts of rhizoma smilacis glabrae, 10-50 parts of angelica dahurica, 5-15 parts of borneol and 2-10 parts of cantharides. The traditional Chinese medicine ointment has the advantages that effects of killing parasites to relieve itching, clearing away heat and drying dampness can be realized by the traditional Chinese medicine ointment, the traditional Chinese medicine ointment is free of toxic and side effects and is innovation in the aspect of medicines for the fungal skin diseases of the livestock and poultry, medicine resistance can be prevented, and the troublesome problems of medicine resistance and toxic and side effects when western medicines are used for treating fungal infection can be effectively solved.
Description
Technical field
The present invention relates to Chinese medicine preparation, particularly a kind of traditional Chinese herb medicine of prevention and therapy poultry dermatomycosis.
Background technology
In veterinary clinic practice, dog dermatomycosis is a kind of very common and multiple disease.Invest poultry skin after pathomycete is excessive, invade skin and hair or toenail, breed in a large number, cause the generation of skin organic disease.The course of disease of poultry dermatomycosis is grown, cures difficulty, is easily recurred, and animal and animal, can propagate mutually between person to person, man and animal, causes serious public health problem.Its average attack rate is about 10% ~ 40%.Sickness rate is high, relapse rate is also high, and oneself receives the concern of veterinary clinic worker day by day.
Modern medicine is thought, the main pathogen of poultry dermatomycosis is Microsporum gypseum, Sabouraudites lanosus, alpha fungus and candidiasis etc., and it occurs to lack of proper care with the excessive adhesion of pathogenic fungi, body self microecological balance, immunity degradation etc. is closely related.
At present, people to dermatomycosis based on topical therapeutic, can system application antifungal agent for obstinate recurrent case.Modal is that antifungal Western medicine such as miconazole (daktarin), clotrimazole, ketoconazole or the econazole of outer painting 1% ~ 2% is treated, for the case of stubbornness general Perhaps immunization functional defect, system antifungal agent such as Te Bicaifen, itraconazole can be selected to treat.Along with widely using of antifungal drug, cause the appearance of many clinical new pathogenic bacterium and endurance strain.Meanwhile, fungus and mammalian cell are all eukaryotic cell, there is a lot of something in common in configuration aspects, often have larger toxicity to host after long-term prescription.The nephrotoxicity of such as amphotericin B, the liver toxicity of imidazoles ketoconazole, the hepatic injury etc. that Te Bicaifen, itraconazole cause.Higher and the drug resistance problems for existing antifungal Western medicine ubiquity toxicity, finds efficient, low toxicity, wide spectrum antifungal new drug extremely urgent.Therefore research and develop the Chinese medicine of the treatment dermatomycosis of high-efficiency low-toxicity, to alleviate western medicine fungal infection time drug resistance and toxicity problem imperative.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide a kind of prevention and therapy poultry dermatomycosis traditional Chinese herb medicine, and effectively can solve prior art can not thoroughly effect a radical cure, and can produce the problem of endurance strain and toxic and side effects.
The technical scheme that the present invention solves is, this traditional Chinese herb medicine is by following weighing scale: Chinese medical concrete 15-30g, stearic acid 8-15g, glyceryl monostearate 2-5g, liquid paraffin 2-5g, vaseline 2-4g, lanoline 2-5g, triethanolamine 0.5-1g, ethyl hydroxybenzoate 0.2g, carbamide 10-20g and distilled water 30-60mL make.
Described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 50-100 part, Radix Sophorae Flavescentis 50-100 part, Fructus Toosendan 10-50 part, Cortex Dictamni 10-50 part, Rhizoma Chuanxiong 10-50 part, Rhizoma Smilacis Glabrae 10-50 part, Radix Angelicae Dahuricae 10-50 part, Borneolum Syntheticum 5-15 part and Mylabris 2-10 part.
The preparation method of traditional Chinese herb medicine, comprises the following steps:
1) Fructus Cnidii in material medicine, Radix Sophorae Flavescentis, Fructus Toosendan, Cortex Dictamni, Rhizoma Chuanxiong, Rhizoma Smilacis Glabrae, the Radix Angelicae Dahuricae and powder of cantharide are broken into coarse powder, load in round-bottomed flask;
2) in round-bottomed flask, the volumetric concentration adding step 1) Raw medicine 6 times of weight is 70% ethanol, soaks 4h;
3) first boiled with high heat, then use slow fire reflux 4h, filter, obtain medicinal liquid;
4) medicinal residues decoct once again, and the volumetric concentration adding step 1) Raw medicine 6 times of weight is 70% ethanol, reflux 2h, and filter, obtain medicinal liquid, merge 2 medicinal liquids, be placed on Rotary Evaporators, 85 DEG C are concentrated into semifluid paste;
5) medicinal liquid of semifluid paste being placed in 80 DEG C of water-baths heating, to be concentrated into relative density be 1.20-1.30, adds Borneolum Syntheticum and be prepared into Chinese medical concrete, for subsequent use;
6) be placed in container by stearic acid, glyceryl monostearate, liquid paraffin, vaseline, lanoline, heating in water bath, to fusing, is incubated, as oil phase on 80 DEG C of water-baths;
7) triethanolamine, ethyl hydroxybenzoate, carbamide distilled water are heated to dissolve, as aqueous phase;
8) slowly poured in oil phase by aqueous phase, add Chinese medical concrete after stirring, limit edged stirs, complete to emulsifying, lets cool and get final product.
The present invention also can routinely preparation method make tincture, lotion or other can be suitable for the dosage form of clinical practice.
Chinese medicine of the present invention is pure natural substance, there is Mutiple Targets, polyphenic feature, there is killing parasites for relieving itching, the effect of heat clearing and damp drying, and have no side effect, almost noresidue, not easily produce drug resistance, easy to use, efficiently solving drug resistance when perplexing western medicine fungal infection and toxic and side effects problem, is the innovation on poultry Fungal Skin medicine.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
In the specific implementation, Chinese medical concrete is made up of the material medicine of following weight parts in the present invention: Fructus Cnidii 51 parts, Radix Sophorae Flavescentis 99 parts, Fructus Toosendan 11 parts, Cortex Dictamni 49 parts, Rhizoma Chuanxiong 11 parts, Rhizoma Smilacis Glabrae 49 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 6 parts and Mylabris 3 parts.
Embodiment 2
In the specific implementation, Chinese medical concrete also can be made up of the material medicine of following weight parts in the present invention: Fructus Cnidii 75 parts, Radix Sophorae Flavescentis 75 parts, Fructus Toosendan 30 parts, Cortex Dictamni 30 parts, Rhizoma Chuanxiong 30 parts, Rhizoma Smilacis Glabrae 30 parts, the Radix Angelicae Dahuricae 30 parts, Borneolum Syntheticum 10 parts and Mylabris 6 parts.
Embodiment 3
In the specific implementation, Chinese medical concrete also can be made up of the material medicine of following weight parts in the present invention: described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 99 parts, Radix Sophorae Flavescentis 51 parts, Fructus Toosendan 49 parts, Cortex Dictamni 11 parts, Rhizoma Chuanxiong 49 parts, Rhizoma Smilacis Glabrae 11 parts, the Radix Angelicae Dahuricae 49 parts, Borneolum Syntheticum 14 parts and Mylabris 9 parts.
Chinese veterinarian's theory is thought, although dermatomycosis occurs in the body surface of animal, has substantial connection with inherent internal organs, QI and blood.Visceral dysfunction, meridians are unfavorable, and QI and blood Kui is stagnant, and wet, heat, worm three heresy seize the opportunity to worm one's way into, and cause local patholoic change.Due to damp viscous, the state of an illness is touching, repeatedly difficult.With the passing of time then impairment of body fluid hematozemia.Stasis blocking venation, the not flourish skin of hyperamization.This disease of Chinese traditional treatment, mainly selects killing parasites for relieving itching, and heat clearing and damp drying agent, based on external treatment, is aided with treatment by oral administration of medicines.In prescription of the present invention, Fructus Cnidii, Fructus Toosendan have killing parasites for relieving itching, heat clearing and damp drying, analgesic effect; Radix Sophorae Flavescentis can antiviral microorganism and toxin thereof; Cortex Dictamni has heat clearing and damp drying, dispelling wind for relieving itching, detoxicating functions, rubella, eczema, scabies etc. caused by the hot noxious dampness of main air; Rhizoma Smilacis Glabrae is removing dampness and detoxicating medicine, can play itching-relieving action, has synergism with the coupling of Radix Sophorae Flavescentis, Cortex Dictamni; Rhizoma Chuanxiong has blood-activating and qi-promoting, mycostasis; The Radix Angelicae Dahuricae has antipyretic, analgesia, antiinflammatory, improves local blood circulation, promotes effect of skin cell metabolism; Mylabris has removing blood stasis Xiao wei, and merit poison phagedenoma, draws red foaming effect.In addition, carbamide can change zoodermic permeability, increases the concentration of medicine at agents area.Reasonable recipe compatibility of the present invention, interacts, both met theory of Chinese medical science, and be applicable to again making external preparation, and be effective to treatment poultry dermatomycosis, and all achieve satisfied effect through repetition test, correlation test data is as follows:
traditional Chinese herb medicine quality analysis of the present invention
1, traditional Chinese herb medicine visual examination: the traditional Chinese herb medicine outward appearance prepared by the present invention is fine and smooth, dark brown, denseness is suitable for, and is easily coated with.
2, traditional Chinese herb medicine pH checks: the Chinese medicine mastic taken a morsel prepared by the present invention, adds dissolve with methanol, uses pH detection paper, and its value is 6.5.
3, traditional Chinese herb medicine tolerance to cold checks: the Chinese medicine mastic prepared by the present invention is placed in-20 DEG C and 4 DEG C of refrigerators, after 24h, without oil-water separation phenomenon.
4, traditional Chinese herb medicine zest checks: get rabbit 2, in its back cropping, expose skin, and back, left side dermal application is containing Chinese medicine mastic, and bare substrate is smeared on right side, observes 24h.Result shows, bare substrate and coating position there are not significant difference, all waits abnormal phenomena without red and swollen.
traditional Chinese herb medicine clinical pharrnacokinetics test of the present invention
One, material
1. test drug: 1) traditional Chinese herb medicine of the present invention.2) miconazole emulsifiable paste (daktarin), Xian-Janssen Pharmaceutical Ltd.;
2. laboratory animal: the sick dog 30 of dermatomycosis, derives from the harmonious pets hospital of Xinyang shellfish shellfish pets hospital and Xinyang.
Two, therapeutic scheme
Sick dog 30, is divided into 2 groups at random, often organizes each 15.One group is miconazole Ointment in Treatment group, by miconazole ointment partial smearing, ointment is covered lesion and peripheral region thereof, 1 time/d, within 1 week, is a course for the treatment of, treats 3 ~ 4 courses for the treatment of, observes and record its curative effect; Two groups is Chinese drug-treated group of the present invention, and traditional Chinese herb medicine is covered lesion and peripheral region thereof by treatment by Chinese herbs, 1 time/d, within 1 week, is a course for the treatment of, treats 3 ~ 4 courses for the treatment of, observes and record its curative effect.
Three, criterion
3.1 skin clinical symptoms
Recovery from illness: epidermis, dorsal body setae, spirit, appetite etc. recover normal, and gargalesthesia disappears, and drug withdrawal was not recurred after 1 week.
Effective: after medication, ill epidermosis change alleviates or temporary extinction to some extent, but drug withdrawal was recurred again after one week.
Invalid: after medication, the clinical symptoms such as diseased epidermis, depilation and spiritual appetite etc. are all unchanged, even increase the weight of.
3.2 Wu Shi lamps are observed
Treat the end of term course for the treatment of, bring dog into darkroom, (Wu Shi lamp minute surface distance affected part 15cm calculates the percent that affected part epiphyte product number (fluoresce skin area) accounts for whole irradiated area to adopt Wu Shi lamp to carry out the irradiation at coating position, contrast each group, and observe dog skin, by the reduction situation of hair.The clinical symptoms of dermatomycosis comprises pimple clinically, water lump, erythema, squama, keratinization, dipping, tumor itch, and use scoring method evaluation respectively, namely (0) is nothing, and (1) is light, and in (2), (3) are heavy.Mark respectively with the end of term course for the treatment of before the treatment, 3 ~ 4 courses for the treatment of of Continuous Observation.
Fungus index=irradiation portion epiphyte product number (fluoresce skin area)/irradiated area × 100%.
Four, statistical procedures
4.1 clinical efficacy statistical results are in table 1.
Table 1 Clinical efficacy comparison
| Grouping | Size of animal | Cure rate (%) | Effective percentage (%) | Inefficiency (%) |
| Western medicine group | 15 | 80 | 93.3 | 6.7 |
| Chinese drug-treated group of the present invention | 15 | 66.7 | 80 | 20 |
Chinese drug-treated group of the present invention and Western medicine group all have good therapeutic effect to treating Dog fungus skin disease, wherein the cure rate of Chinese drug-treated group is 80%, the cure rate of Western medicine group is 66.7%, and total effective rate is respectively 93.3% and 80%, and comparatively gram Western medicine group is effective for this prescription cure rate clinically as seen.And through repeated tests, all achieve identical or akin result, show that steady quality is reliable, drug safety, good effect.
Traditional Chinese herb medicine of the present invention, through making other dosage forms, all achieves identical or close result in an experiment, will not enumerate; prevent tired stating; arbitrary dosage form that all employing the application Chinese prescriptions are made, and be used for the treatment of the medicine of poultry dermatomycosis, all belong to the scope of the application's protection.
Traditional Chinese herb medicine of the present invention has the effects such as killing parasites for relieving itching, heat clearing and damp drying, analgesia, to reach killing fungus, regulation of skin wet-heat durability, to improve the effect such as immunity, antiinflammatory, to poultry dermatomycosis, there is treatment and preventive effect preferably, having good actual application value, is the innovation on treatment poultry Fungal Skin medicine.
The present invention, compared with existing technology, has the following advantages:
1. pure Chinese medicinal preparation, has anti-multiple pathogenic fungus, and have no drug resistance generation, is the medication of a kind of novel, effective solution poultry dermatomycosis;
2. have Mutiple Targets, polyphenic feature, can efficiently solve drug resistance when perplexing western medicine fungal infection and toxic and side effects problem, be the innovation on poultry Fungal Skin medicine;
3. after medicine being prepared into ointment, easy to use, curative effect is fast, and drug effect is obvious, and this medicine is gentle to the zest of mucosa, has no adverse reaction;
4. prevention and cure rate high, clinical trial effective percentage, effect is better than antibiotic;
5. preparation technology is simple, and quality standard is controlled, and be applicable to large-scale production needs, economic and social benefit is huge.
Claims (5)
1. the traditional Chinese herb medicine of a prevention and therapy poultry dermatomycosis, it is characterized in that, this traditional Chinese herb medicine is by following weighing scale: Chinese medical concrete 15-30g, stearic acid 8-15g, glyceryl monostearate 2-5g, liquid paraffin 2-5g, vaseline 2-4g, lanoline 2-5g, triethanolamine 0.5-1g, ethyl hydroxybenzoate 0.2g, carbamide 10-20g and distilled water 30-60mL make;
Described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 50-100 part, Radix Sophorae Flavescentis 50-100 part, Fructus Toosendan 10-50 part, Cortex Dictamni 10-50 part, Rhizoma Chuanxiong 10-50 part, Rhizoma Smilacis Glabrae 10-50 part, Radix Angelicae Dahuricae 10-50 part, Borneolum Syntheticum 5-15 part and Mylabris 2-10 part.
2. the traditional Chinese herb medicine of prevention and therapy poultry dermatomycosis according to claim 1, it is characterized in that, described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 51 parts, Radix Sophorae Flavescentis 99 parts, Fructus Toosendan 11 parts, Cortex Dictamni 49 parts, Rhizoma Chuanxiong 11 parts, Rhizoma Smilacis Glabrae 49 parts, the Radix Angelicae Dahuricae 11 parts, Borneolum Syntheticum 6 parts and Mylabris 3 parts.
3. the traditional Chinese herb medicine of prevention and therapy poultry dermatomycosis according to claim 1, it is characterized in that, described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 75 parts, Radix Sophorae Flavescentis 75 parts, Fructus Toosendan 30 parts, Cortex Dictamni 30 parts, Rhizoma Chuanxiong 30 parts, Rhizoma Smilacis Glabrae 30 parts, the Radix Angelicae Dahuricae 30 parts, Borneolum Syntheticum 10 parts and Mylabris 6 parts.
4. the traditional Chinese herb medicine of prevention and therapy poultry dermatomycosis according to claim 1, it is characterized in that, described Chinese medical concrete is made up of the material medicine of following weight parts: described Chinese medical concrete is made up of the material medicine of following weight parts: Fructus Cnidii 99 parts, Radix Sophorae Flavescentis 51 parts, Fructus Toosendan 49 parts, Cortex Dictamni 11 parts, Rhizoma Chuanxiong 49 parts, Rhizoma Smilacis Glabrae 11 parts, the Radix Angelicae Dahuricae 49 parts, Borneolum Syntheticum 14 parts and Mylabris 9 parts.
5. the preparation method of the traditional Chinese herb medicine of the prevention and therapy poultry dermatomycosis described in any one of claim 1,2,3 or 4, is characterized in that, comprise the following steps:
1) Fructus Cnidii in material medicine, Radix Sophorae Flavescentis, Fructus Toosendan, Cortex Dictamni, Rhizoma Chuanxiong, Rhizoma Smilacis Glabrae, the Radix Angelicae Dahuricae and powder of cantharide are broken into coarse powder, load in round-bottomed flask;
2) in round-bottomed flask, the volumetric concentration adding step 1) Raw medicine 6 times of weight is 70% ethanol, soaks 4h;
3) first boiled with high heat, then use slow fire reflux 4h, filter, obtain medicinal liquid;
4) medicinal residues decoct once again, and the volumetric concentration adding step 1) Raw medicine 6 times of weight is 70% ethanol, reflux 2h, and filter, obtain medicinal liquid, merge 2 medicinal liquids, be placed on Rotary Evaporators, 85 DEG C are concentrated into semifluid paste;
5) medicinal liquid of semifluid paste being placed in 80 DEG C of water-baths heating, to be concentrated into relative density be 1.20-1.30, adds Borneolum Syntheticum and be prepared into Chinese medical concrete, for subsequent use;
6) be placed in container by stearic acid, glyceryl monostearate, liquid paraffin, vaseline, lanoline, heating in water bath, to fusing, is incubated, as oil phase on 80 DEG C of water-baths;
7) triethanolamine, ethyl hydroxybenzoate, carbamide distilled water are heated to dissolve, as aqueous phase;
8) slowly poured in oil phase by aqueous phase, add Chinese medical concrete after stirring, limit edged stirs, complete to emulsifying, lets cool and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510797476.7A CN105267800A (en) | 2015-11-18 | 2015-11-18 | Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510797476.7A CN105267800A (en) | 2015-11-18 | 2015-11-18 | Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105267800A true CN105267800A (en) | 2016-01-27 |
Family
ID=55138189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510797476.7A Pending CN105267800A (en) | 2015-11-18 | 2015-11-18 | Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105267800A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468957A (en) * | 2017-10-20 | 2017-12-15 | 贵州省潘念种养殖有限公司 | Ox skin disease Chinese medicine preparation |
| CN107648526A (en) * | 2017-10-20 | 2018-02-02 | 贵州松羽禽业有限公司 | A kind of Chinese medicine preparation |
| CN110693965A (en) * | 2019-10-29 | 2020-01-17 | 西藏自治区农牧科学院畜牧兽医研究所 | Compound traditional Chinese medicine ointment for treating plateau cattle and sheep skin diseases |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1164998A (en) * | 1997-01-27 | 1997-11-19 | 徐钟镇 | Skin washing liquid and its preparation method |
| US5843467A (en) * | 1996-07-15 | 1998-12-01 | Ambroziewigz; Wieslaw | Topical ointment consisting of animal fat, plantain lancetowata, and calendula and methods of producing the same |
| CN104274389A (en) * | 2013-07-04 | 2015-01-14 | 青岛康地恩药业股份有限公司 | Ointment containing 2-mercaptobenzothiazole, and preparation method thereof |
-
2015
- 2015-11-18 CN CN201510797476.7A patent/CN105267800A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843467A (en) * | 1996-07-15 | 1998-12-01 | Ambroziewigz; Wieslaw | Topical ointment consisting of animal fat, plantain lancetowata, and calendula and methods of producing the same |
| CN1164998A (en) * | 1997-01-27 | 1997-11-19 | 徐钟镇 | Skin washing liquid and its preparation method |
| CN104274389A (en) * | 2013-07-04 | 2015-01-14 | 青岛康地恩药业股份有限公司 | Ointment containing 2-mercaptobenzothiazole, and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 何静荣: "外洗药治疗猫皮肤真菌病", 《中兽医学杂志》 * |
| 张华山: "《中医学秘里求真》", 30 November 2011, 中医古籍出版社 * |
| 欧阳恒等: "《实用皮肤病诊疗手册》", 31 August 2013, 人民军医出版社 * |
| 陈洪轩等: "《药剂辅料实用技术》", 31 January 2014, 河南大学出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468957A (en) * | 2017-10-20 | 2017-12-15 | 贵州省潘念种养殖有限公司 | Ox skin disease Chinese medicine preparation |
| CN107648526A (en) * | 2017-10-20 | 2018-02-02 | 贵州松羽禽业有限公司 | A kind of Chinese medicine preparation |
| CN110693965A (en) * | 2019-10-29 | 2020-01-17 | 西藏自治区农牧科学院畜牧兽医研究所 | Compound traditional Chinese medicine ointment for treating plateau cattle and sheep skin diseases |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6027728A (en) | Herbal skin regeneration composition and method | |
| CN103341104B (en) | External traditional Chinese medicine for treating skin diseases | |
| CN102614440A (en) | Multi-herb antibacterial liquid | |
| CN103961636B (en) | Orthopedic disease treatment external application traditional Chinese medicine composition, preparation method and application thereof | |
| CN104474076A (en) | Traditional Chinese medicine composition for treating eczema | |
| CN103041173A (en) | Traditional Chinese medicine external preparation for curing dermatitis and eczema and preparing method thereof | |
| CN106474350A (en) | A kind of plant antibiotic compound spray and preparation method thereof | |
| CN105267800A (en) | Traditional Chinese medicine ointment for preventing and treating fungal skin diseases of livestock and poultry | |
| CN102552761A (en) | Chinese medicinal pills for treating psoriasis | |
| CN102755573A (en) | External use traditional Chinese medicine for treating onychomycosis | |
| CN107260855A (en) | One kind treats dermopathic medicine | |
| CN104095970B (en) | A kind of External apply medicinal wine for the treatment of verruca vulgaris | |
| CN104056218B (en) | Treat dermopathic medicine and preparation method thereof | |
| CN104324317B (en) | A kind of Chinese medicine composition and medical usage for treating fibroid | |
| CN103239661B (en) | Chinese medicine combination for treating tinea pedis and preparation method of Chinese medicine combination | |
| CN105287742A (en) | Ointment capable of controlling mosquito bite and preparation method thereof | |
| CN102784224B (en) | Traditional Chinese medicine compound lotion for treating scaly hyperkeratotic tinea manual and tinea pedis and preparation method thereof | |
| CN101797315B (en) | Traditional Chinese medicine composition capable of treating various skin diseases | |
| CN103989767B (en) | A kind of treat verruca plana pharmaceutical composition and preparation technology and application | |
| CN103341044A (en) | Itching-relieving compound preparation and preparation method thereof | |
| CN108524734A (en) | A kind of ointment for scald and preparation method thereof | |
| CN115040600B (en) | Traditional Chinese medicine composition for treating scalp psoriasis | |
| CN102178732B (en) | Chinese medicine nanoemulsion spraying agent for treating chronic eczema | |
| CN103599253B (en) | Traditional Chinese medicine composition for treating winter pruritus of old people | |
| CN105616947A (en) | Heat and dampness removing traditional Chinese medicine for treating acute gouty arthritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160127 |
|
| RJ01 | Rejection of invention patent application after publication |