CN1127137A - External medicine for burn and producing method - Google Patents
External medicine for burn and producing method Download PDFInfo
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- CN1127137A CN1127137A CN 95116582 CN95116582A CN1127137A CN 1127137 A CN1127137 A CN 1127137A CN 95116582 CN95116582 CN 95116582 CN 95116582 A CN95116582 A CN 95116582A CN 1127137 A CN1127137 A CN 1127137A
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- burn
- borax
- realgar
- alumen
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Abstract
The invented medicine consists of realgar, dark plum, borax, borneol, sumac gallnut, tuber of hyacinth bletilla, sanguisorba root, trogoterus dung and alum. The tannic acid family substance, potassium aluminum sulfate family substance, dextrorotary borneol, multikind of vitamins and other acidic substance containing is said burn medicine have killing action to staphylococcus aureus, B. proteus, B. coli, pseudomonas aeruginosa and B. anthracis.
Description
The present invention relates to a kind of burn, wound medicine and production method thereof, especially refer to a kind of have antibiotic, antiinflammatory, convergence, anticorrosion and activate the medicine of body function, its tannins that contains, aluminium potassium sulfate class, dextro Borneolum Syntheticum, multivitamin and other acid have killing action to staphylococcus aureus, Bacillus proteus, colibacillus, bacillus pyocyaneus, anthrax bacillus etc.
Be that burn, outer wound all are to bring very big misery to human body, especially large-area burning, wound bring immeasurable infringement for especially people's life, and the medicine kind of present this respect seldom, and the effect of treatment, the performance of, antiinflammatory antibiotic as it, aspect such as anticorrosion is not very good, and these medicines do not have good facilitation effect to organic resurrection and healing.
Purpose of the present invention just is to overcome the deficiency that existing burning, wound exist with medicine, provide a kind of antiinflammatory, pain relieving, infection, convergence, anticorrosion, profit skin are arranged, promote epithelial cell and granulation growth and suppress blood and pull gathering for a short time, promote microcirculatory circulation and eliminate burning, traumatic and the production method thereof of the effect of edema.
Burning of the present invention, its composition of traumatic and proportioning (parts by weight) are:
Title: the best proportioning of proportioning:
Realgar: 20-28 part 22-25 part
Fructus Mume: 90-110 part 98-102 part
Borax: 50-70 part 57-63 part
Borneolum Syntheticum: 50-70 part 57-62 part
Galla Chinensis: 90-110 part 98-102 part
The Pseudobulbus Bletillae (Rhizoma Bletillae): 90-110 part 97-101 part
Radix Sanguisorbae: 90-110 part 99-103 part
Oletum Trogopterori: 50-70 part 58-62 part
Alumen: 90-110 part 97-101 part
Wherein, contained its pharmacology of each composition is respectively:
1. Realgar: the various skin fungus is had inhibitory action, to staphylococcus aureus, Bacillus proteus,
Bacillus pyocyaneus, escherichia coli have inhibition and killing action.
2. Fructus Mume: fruit contains citric acid 19%, malic acid 15%, succinic acid, carbohydrate, paddy steroid
Alcohol, ceroidlike material and olive class sample material contain hydrocyanic acid, external when maturation
During test, decocting liquid (1: 1) is to anthrax bacillus, bacillus pyocyaneus, escherichia coli, Fructus Vitis viniferae
Coccus, tubercule bacillus have inhibitory action (flat band method, paper disk method).3. Borax: the Main Ingredients and Appearance sodium tetraborate is a weak base, and the inhibition bacterial action is arranged, to escherichia coli,
Various bacteria such as bacillus pyocyaneus, anthrax bacillus has inhibitory action.4. Borneolum Syntheticum: contain dextro Borneolum Syntheticum, contain multiple terpenoid composition in the resin of Borneolum Syntheticum He in the volatile oil.
Borneolum Syntheticum is very light for sensorineural local excitation, but gentle anticorrosion and pain relieving is arranged
Effect has antibacterial in external (flat pulling manipulation, mixing method) with higher concentration (0.5%)
Effect can be used for neuralgia and antiinflammatory.5. Alumen: be alkaline potassium aluminum sulfate.Staphylococcus aureus, Bacillus proteus, bacillus pyocyaneus are reached
Various bacteria such as anthrax bacillus have inhibitory action, high concentration to tubercule bacillus have suppress and
Killing action (will Hayes, paper dish method, flat band method), Alumen have stronger hidroschesis and
The effect of sclerosis skin, Alumen directly is put in the bleeding part anastalsis immediately, bright
Vitriol precipitates immediately at the external serum that can make, and the effect of stronger coagulated protein is arranged.6. Oletum Trogopterori: contain the retinoid material, still contain various kinds of resin, carbamide, uric acid etc., Oletum Trogopterori
Various bacteria and fungus there is inhibitory action.7. Galla Chinensis: contain a large amount of tannic acids and resin, fat, starch, it has (1) astriction: because
Wherein contained tannic acid has precipitation to protein, wherein skin, mucosa, ulcer
Behind the contact tannic acid, tissue protein promptly is solidified, and forms one deck tunicle and is convergence and does
With, the also oppressed contraction of little blood vessel simultaneously, blood clotting and be anastalsis, gland
Cell protein is solidified and causes that secretion suppresses, and produces the mucosa drying, the teleneuron egg
The precipitation of white matter can be faint local anesthesia phenomenon; (2): antibacterial action: to gold
Staphylococcus aureus, bacillus pyocyaneus, anthrax bacillus etc. have the inhibition killing action, five times
Sub-decoct is to influenza first type PR
3Strain virus has inhibitory action.8. Radix Sanguisorbae: it is about 17% that root contains tannin, triterpenoid saponin 2.5～4%, and isolating Saponin has: ground
The elm glucoside produces sloping film alkyd after the hydrolysis, arabinose, glucose, ziyu glycoside,
Sanguisorbin etc.Wherein, (1) is to the therapeutical effect of experimental scald: use for rabbit or Canis familiaris L.
Hot water scalds the II-III degree, and the external Radix Sangusorbae powder has certain curative effect, and wound surface oozes out few, than
Drying and infection and dead less.Tannin of from Radix Sanguisorbae, extracting or commercially available tanning
Matter is all not as the Radix Sangusorbae powder good effect, and clinical curative effect to scald is not only contained tannin,
Also have other factor to participate in.(2) anastalsis: the oral charred Radix Sanguisorbae decoct of rabbit makes and coagulates
The blood time obviously shortens, and frog limb perfusion experiment visible vessels is shunk.(3) antibacterial action:
Radix Sanguisorbae all has inhibition to staphylococcus aureus, bacillus pyocyaneus, tubercule bacillus etc. and kills
The effect of going out.9. the Pseudobulbus Bletillae (Rhizoma Bletillae): water content 14.6%, starch 30.48%, glucose 1.5%, and volatile oil, sticking
Liquid matter, root contains bletilla mannan.Wherein, (1) anastalsis: Pseudobulbus Bletillae (Rhizoma Bletillae) pulverizing or white
Splendid achnatherum decoct gained Colloidal fluid mixes the starch oven dry and grinds, and carries out hemostasis trial, 7 in Canis famililiaris L.
There are 6 all in 6 minutes, to reach satisfied haemostatic effect among the experimenter, use pure starch
Or the starch sponge hemostasis, effect is all relatively poor; " gauze " or water extraction with water extraction
Liquid is covered in Canis famililiaris L., spleen and Hepar Leporis seu Oryctolagi or thigh flesh through cold drying or spraying drying powder-forming
Meat carries out hemostasis trial, hemorrhage can stopping immediately; Hepatectomy or muscle crosscut cause
Hemorrhage, it is more promptly to be that wound surface oozes out, and also medicine can not be washed away, and all animals is not all used
Antibiotics does not suppurate; Pseudobulbus Bletillae (Rhizoma Bletillae) powder is to Hepar Leporis seu Oryctolagi, Canis famililiaris L., and the going out of femoral artery
Blood also has tangible haemostatic effect, and the colloid that the anastalsis of the Pseudobulbus Bletillae (Rhizoma Bletillae) contains with it has
Close.
The production process of external medicine for burn of the present invention is: by proportioning Alumen, Borax, Realgar are mixed, porphyrize is to 120 orders, stir and heat, collect fraction from 153 ℃～285 ℃, with crystalline fraction and other promptly get this product by the component mixed grinding that proportioning takes by weighing.
In addition, this product also can be made into paste or aerosol apparatus preparation.
External medicine for burn using method of the present invention is: (one) shallow II ° is burnt soup and hinders: after the conventional debridement, be sprinkling upon equably on the wound surface with powder, keep wound surface to ventilate drying.Look the wound surface situation changed dressings once on the 3rd.Do not have infection as wound surface, let alone " when a melon is ripe it falls off its stem ", primary healing.(2) deep burn: after conventional debridement, powder is sprinkling upon on the wound surface equably, powder is thicker than the minor burn drug of topical application; The 3rd day begins to change dressings, and looks wound surface and whole body situation, and the thickness that decision is changed dressings is until recovery from illness.(3) infective wound surface: after fully removing slough and secretions, apply equably on wound surface with powder, the gauze wrapping is changed dressings once, until recovery from illness every day.According to thousands of routine analysiss of cases, this medicament injures the common bacteria of various wound tuberculous ulcers to burn and scald, as the hemolytic staphylococcus aureus, escherichia coli, bacillus pyocyaneus, Bacillus proteus, anthrax bacillus, tubercule bacillus and some virus are all killed or inhibitory action.
Describe below by the curative effect of some cases burning of the present invention, traumatic.
Case one: the king * *, woman, 17 years old, the Zhumadian people, Jiaozhuo * * the chemical plant casual labour, on May 26th, 1, because of work is jumped in the concentrated sulphuric acid bucket accidentally the time, two lower limbs and the hypogastric region area of burning reaches 40% of whole body, the degree of depth of burning reach III °, anxious giving * * hospital's treatment, after three days, the pain increased for the patient, and many places infection suppurates then is with the external medicine for burn of migrating, cicatrix is not stayed in day recovery from illness surplus treating 20.
Case two: Lee * *, 25 years old, people from Gushi County, on February tenth, 1, on kitchen range, warm oneself, left hand knocks the boiling water pot accidentally over, scalds seriously to rot, through * * hospitalize requires the family numbers of patients signature to clip left hand, family numbers of patients is disagreed with, so seek medical advice, through this medicament control ten surplus day recovery from illness, do not stay cicatrix.
Case three: practise * *, the cadre of place, gardens, Jiaozhuo, on October 16th, 1, because of with tape measure amount high-voltage line apart from ground level, unfortunate by 3.5 ten thousand volts of high-voltage electric injuries, injure left hand tiger and left foot, anxious at that time sending * * hospital's treatment, through skin-grafting, ultraviolet radiation, poor effect, left hand and the unusual many places of the serious pain of left lower limb edema infection suppurates are through using external medicine for burn, day swollen disappearing surplus in the of ten, wound healing, and the work of now having gone to work of fully recovering.
Case four: open * *, woman 36 years old, Jiaozuo City three families of workers and staff of making pottery, on April 21st, 1 early in the morning, because of butt is accidentally gone in the boiled water pot, facial all scalds, edema is festered, through * * three days poor effect of hospitalize, so change dressings for three times with external medicine for burn, cicatrix is not stayed in Ninth Heaven recovery from illness.
Case five: paddy * *, man, 65 years old, treat Wang Zhenren, I go here and there surplus the diabetes ten year, body constitution skeletonize weakness, stab left hand when August 20 was in cornhusking in 93 year accidentally, suddenly deliver to the wrapping of town hospital, left hand swelling pain after a few days, anxious to the city * * hospital surgery seeks medical advice, the most of infection suppurates of left hand on inspection, require the patient to do amputation, otherwise very easily cause septicemia, consequence is hardly imaginable.The patient is reluctant to operate, and adopts Drug therapy of the present invention, surplus the medication 20 day, has kept left hand, and has obtained complete.
Case six: open * *, the woman, 43 years old, Jiaozuo City chemical industry two workmans of factory because of menoxenia, injected Progesterone and infection suppurates 94 on March 19,, and are painful unusual, handicapped through multi-treatment invalid (repeatedly operative drainage forms fistula).Through using this pharmaceutical treatment, ten days and heal.
Case seven: Liu * *, the woman, 16 years old, the student of technical secondary school for employees of the Jiaozuo City federation of trade unions, examine in August, 95, and it is surplus half a year that a fistula is given birth at private prosecution temple place, invalid through multi-treatment, through healing with this pharmaceutical treatment Ninth Heaven.
Case eight: appoint * *, man, 51 years old, the driver of Jiaozuo City power supply administration, be in when building a house in June, 809, and left index finger is injured by a crashing object fracture by hammer, through certain clinic's wrapping, swelling pain afterwards, the burning that occurs together, anxious to the city * * hospitalize is diagnosed as osteomyelitis, must do amputation, the patient is reluctant to do amputation, adopts the medicine for treatment of this medicine three times, ten days and heal.
Case nine: Liu * *, woman, 28 years old, the people's police of public security section of jiefang Division Jiaozuo Public Security Bureau, JIUYUE was 25 in 95 years, accidentally right knee joint was damaged, and wound surface such as Semen Juglandis are big, and pain is unusual, handicapped, through * * hospital's wrapping postoperative infection suppuration, adopt this pharmaceutical treatment, three are complete.
External medicine for burn of the present invention has antiinflammatory, pain relieving, and infection is restrained anticorrosionly, and the profit skin promotes growth of epithelial cell and granulation and anticoagulant, promotes the circulation of microcirculation and eliminates the effect of edema.Wound surface oozes out less after using this medicament, and the Water-Electrolyte disorder does not take place, and does not infect, more the back preventing from scar.Use this medicament not to be subjected to any condition, area, site limitation, and short treating period, the effect of paying do not had.This medicine not only has special effect to burn and scald, and to various wounds, weapons injure various intractable surgical diseases, have one's own knack.According to clinical use for many years, do surplus routine patient through controlling number, total effective rate 100%, cure rate reaches (all non-first-hand extra heavy case of loser) more than 98%, no matter is that water, fire, strong acid or high-tension electricity are burnt wherein, the area size of no matter hindering, the depth is in denying, as timely this medicament of use, month surplus at most, day recovery from illness surplus in the of ten at least.
Embodiment 1
With Realgar 24 grams, Borax 60 grams, Alumen 100 gram mixings, porphyrize is to 120 orders, stir and heat, collect 153 ℃～285 ℃ crystallization fraction, and then add Fructus Mume 100 grams, Borneolum Syntheticum 60 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 100 grams, Radix Sanguisorbae 100 grams, Oletum Trogopterori 60 grams, and Galla Chinensis 100 grams, the mixing porphyrize promptly gets this medicine.
Embodiment 2
The specific embodiment is identical with embodiment 1, and different is to select Realgar 20 grams, Fructus Mume 90 grams, Borax 50 grams, Borneolum Syntheticum 50 grams, Galla Chinensis 90 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 90 grams, Radix Sanguisorbae 90 grams, Oletum Trogopterori 50 grams, Alumen 90 grams for use.
Embodiment 3
The specific embodiment is identical with embodiment 1, and different is to select Realgar 22 grams, Fructus Mume 98 grams, Borax 57 grams, Borneolum Syntheticum 57 grams, Galla Chinensis 98 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 97 grams, Radix Sanguisorbae 99 grams, Oletum Trogopterori 58 grams, Alumen 97 grams for use.
Embodiment 4
The specific embodiment is identical with embodiment 1, and different is to select Realgar 25 grams, Fructus Mume 102 grams, Borax 63 grams, Borneolum Syntheticum 62 grams, Galla Chinensis 102 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 101 grams, Radix Sanguisorbae 103 grams, Oletum Trogopterori 62 grams, Alumen 101 grams for use.
Embodiment 5
The specific embodiment is identical with embodiment 1, and different is to select Realgar 28 grams, Fructus Mume 110 grams, Borax 70 grams, Borneolum Syntheticum 70 grams, Galla Chinensis 110 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 110 grams, Radix Sanguisorbae 110 grams, Oletum Trogopterori 70 grams, Alumen 110 grams for use.
Claims (4)
1. external medicine for burn comprises Realgar, Fructus Mume, Borax, Borneolum Syntheticum, Galla Chinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Sanguisorbae, Oletum Trogopterori, Alumen.
2. external medicine for burn according to claim 1, its proportioning of wherein said component is (parts by weight are represented):
Realgar: 20-28 part,
Fructus Mume: 90-110 part,
Borax: 50-70 part,
Borneolum Syntheticum: 50-70 part,
Galla Chinensis: 90-110 part,
The Pseudobulbus Bletillae (Rhizoma Bletillae): 90-110 part,
Radix Sanguisorbae: 90-110 part,
Oletum Trogopterori: 50-70 part,
Alumen: 90-110 part,
3. external medicine for burn according to claim 2, the proportioning of wherein said component is (parts by weight are represented):
Realgar: 22-25 part,
Fructus Mume: 98-102 part,
Borax: 57-63 part,
Borneolum Syntheticum: 57-62 part,
Galla Chinensis: 98-102 part,
The Pseudobulbus Bletillae (Rhizoma Bletillae): 97-101 part,
Radix Sanguisorbae: 99-103 part,
Oletum Trogopterori: 58-62 part,
Alumen: 97-101 part,
4. according to the production method of any described external medicine for burn in the claim 1～3, wherein will mix by Alumen, Borax, the Realgar that proportioning is selected for use, porphyrize is to 120 orders, heat after stirring, collection is from 153 ℃～285 ℃ fraction, with this fraction and other component mixed grinding of selecting for use by proportioning.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95116582 CN1127137A (en) | 1995-10-19 | 1995-10-19 | External medicine for burn and producing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95116582 CN1127137A (en) | 1995-10-19 | 1995-10-19 | External medicine for burn and producing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1127137A true CN1127137A (en) | 1996-07-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95116582 Pending CN1127137A (en) | 1995-10-19 | 1995-10-19 | External medicine for burn and producing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1127137A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716336A (en) * | 2012-06-01 | 2012-10-10 | 蒋金洲 | External use ointment for treating herpes zoster |
| CN104027483A (en) * | 2014-05-13 | 2014-09-10 | 于婷 | Traditional Chinese medicine ointment for treating burn and scald and preparation method thereof |
| CN106668929A (en) * | 2017-01-20 | 2017-05-17 | 中国标准化研究院 | Tannin adhesive bandage and preparation method thereof |
-
1995
- 1995-10-19 CN CN 95116582 patent/CN1127137A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716336A (en) * | 2012-06-01 | 2012-10-10 | 蒋金洲 | External use ointment for treating herpes zoster |
| CN102716336B (en) * | 2012-06-01 | 2014-04-16 | 蒋金洲 | External use ointment for treating herpes zoster |
| CN104027483A (en) * | 2014-05-13 | 2014-09-10 | 于婷 | Traditional Chinese medicine ointment for treating burn and scald and preparation method thereof |
| CN106668929A (en) * | 2017-01-20 | 2017-05-17 | 中国标准化研究院 | Tannin adhesive bandage and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |