CN107233360B - A Chinese medicinal composition for treating scald and burn - Google Patents

A Chinese medicinal composition for treating scald and burn Download PDF

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CN107233360B
CN107233360B CN201710494004.3A CN201710494004A CN107233360B CN 107233360 B CN107233360 B CN 107233360B CN 201710494004 A CN201710494004 A CN 201710494004A CN 107233360 B CN107233360 B CN 107233360B
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CN107233360A (en
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刘国灿
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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Abstract

A traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 320 portions of royal jelly 280, 90 to 110 portions of honey, 220 portions of propolis 180 and 18 to 22 portions of bee hemolymph. The traditional Chinese medicine for treating scalds and burns prepared by the formula has the effects of quickly relieving pain, clearing away heat and toxic materials, moistening skin and promoting granulation, and has the advantages of simple formula, no toxic or side effect, quick cure and no scar after cure.

Description

A Chinese medicinal composition for treating scald and burn
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating scalds and burns.
Background
Scalding and burning are common accidental injuries in life, wherein the burning is the burning of human skin, limbs and internal organs caused by flames of various chemical substances, power sources and the like, for example, the burning of human body caused by the flames of alcohol, liquefied gas, natural gas, electric shock and the like, the scalding is the burning of liquid, solid, metal, chemical substances and the like on the surface layer and the deep layer of the human skin, for example, the burning of boiled water, oil, iron, lead, hydrochloric acid, sulfuric acid, strong alkali and the like on the human body, the burning and the burning of light people can cause the burning of the skin epidermis, the burning of dermis and subcutaneous adipose tissue, and the burning of muscle, bone and even internal organs for heavy people; the large-area burn can cause shock and other general symptoms and death of the human body. At present, a plurality of medicines for treating burns and scalds are available, and the patent application with the application number of CN 200610045266.3 and the name of 'a medicinal composition for treating burns and a preparation method thereof' discloses a medicinal composition for treating burns, which is prepared from the following raw materials in parts by weight: 3-15 parts of propolis, 80-100 parts of sesame oil, 2-10 parts of angelica, 1-5 parts of honey and 1-5 parts of royal jelly. The ointment prepared by the patent can supply nutrition and bioactive substances to wound tissue exogenously, activate regenerated tissue and promote wound repair, but for the wounded wound, the self-absorption nutrition is poor, so the wound repair is slow, and the treatment time is long.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine for treating scalds and burns to overcome the defects of the prior art.
The purpose of the invention is realized by the following technical scheme:
a traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 320 portions of royal jelly 280, 90 to 110 portions of honey, 220 portions of propolis 180 and 18 to 22 portions of bee hemolymph.
The traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 300 parts of royal jelly, 100 parts of honey, 200 parts of propolis and 20 parts of bee hemolymph.
The preparation method of the traditional Chinese medicine for treating scalds and burns comprises the following steps:
(1) weighing the propolis in parts by weight, completely melting the propolis at 60-70 ℃, and stopping heating;
(2) when the temperature is reduced to 40-50 ℃, adding the royal jelly and the honey in parts by weight while stirring, and continuously stirring to mix;
(3) when the temperature is reduced to room temperature, the honey hemolymph with the weight parts is added while stirring, and the mixture is uniformly mixed to obtain the honey hemolymph.
In the formula of the invention, the royal jelly contains 10-hydroxy-2-decenoic acid besides various amino acids, vitamins, hormones, enzymes and various bioactive substances, so that the royal jelly has a strong bactericidal effect; the honey is neutral in nature, bitter, pungent and slightly sweet in taste, has the effects of moistening skin, promoting granulation, diminishing inflammation and relieving pain, and can be used for treating gastric ulcer, dental ulcer, burn and scald, skin pain, radiation protection and other diseases; propolis contains rich and unique bioactive substances, has the effects of resisting bacteria, diminishing inflammation, relieving itching, resisting oxidation, enhancing immunity, reducing blood sugar, reducing blood fat, resisting tumors and the like, is used for tonifying weakness by oral administration, dissolving turbid fat, relieving thirst, and detoxifying and reducing swelling by external application; the bee hemolymph is one of main components in a bee body, accounts for 25-30 percent of the weight of the bee body, plays roles of transporting in-vivo substances, nutrition and humoral immunity, is blood sample liquid existing in an open circulatory system of the bee, is colorless and transparent, has the characteristics of blood and hemolymph, is mainly used for transporting substances such as nutrition, ions, hormone and the like, the content of the hemolymph comprises two parts of plasma and blood cells, inorganic ions such as sodium, potassium, calcium, magnesium and the like, free amino acid, organic acids such as malic acid, citrate, succinate and the like, lipids, enzymes, antimicrobial peptide, hormone and the like, the blood cells comprise protocyte, plasma cells, granular cells, crimson-like cells, globular blood cells and thrombocyte, and are important components of the immune defense function of an organism, wherein the antimicrobial peptide has broad-spectrum antimicrobial activity, the target can be quickly searched and killed. In the invention, the bee hemolymph is obtained by inserting a capillary between the 3 rd to 4 th section of the back plate of the abdomen of the bee.
In the raw materials, the royal jelly, the honey, the propolis and the bee hemolymph have the effects of sterilizing, diminishing inflammation, relieving pain, moistening skin and promoting tissue regeneration, particularly the propolis and the bee hemolymph have broad-spectrum antibacterial activity, can not only quickly relieve the pain of a patient, but also achieve the aim of resisting infection, in addition, the royal jelly, the honey, the propolis and the bee hemolymph all contain rich nutrient substances and bioactive substances, can provide various nutrients for a burn or scald part, activate and start regenerative cells, are beneficial to the regeneration and repair of skin tissues of the burn or scald part, and the bee hemolymph has the function of transporting the nutrients, ions, hormones and other substances, can accelerate the absorption of the wound surface of a wound to the nutrient substances and the bioactive substances, accelerate the regeneration and repair of the skin tissues and enable the wound part to heal as soon as possible.
Detailed Description
Example 1
A traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 320 portions of royal jelly 280, 90 to 110 portions of honey, 220 portions of propolis 180 and 18 to 22 portions of bee hemolymph.
The preparation method of the traditional Chinese medicine for treating scalds and burns comprises the following steps:
(1) weighing the propolis in parts by weight, completely melting the propolis at 60-70 ℃, and stopping heating;
(2) when the temperature is reduced to 40-50 ℃, adding the royal jelly and the honey in parts by weight while stirring, and continuously stirring to mix;
(3) when the temperature is reduced to room temperature, the honey hemolymph with the weight parts is added while stirring, and the mixture is uniformly mixed to obtain the honey hemolymph.
When in use, the plaster can be directly coated on the injured part with the thickness of about 1mm, generally, the dressing change is carried out once after 6-8 hours, the medicine is applied to the injured part after exposure, and the plaster can also be wrapped by gauze.
Example 2
A traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 300 parts of royal jelly, 100 parts of honey, 200 parts of propolis and 20 parts of bee hemolymph.
The preparation method of the traditional Chinese medicine for treating scalds and burns comprises the following steps:
(1) weighing the propolis in parts by weight, completely melting the propolis at 65 ℃, and stopping heating;
(2) when the temperature is reduced to 45 ℃, adding the royal jelly and the honey in parts by weight while stirring, and continuously stirring to mix the royal jelly and the honey;
(3) when the temperature is reduced to room temperature, the honey hemolymph with the weight parts is added while stirring, and the mixture is uniformly mixed to obtain the honey hemolymph.
The traditional Chinese medicine for treating scalds and burns prepared by adopting the proportion and the method has the effects of quickly relieving pain, clearing away heat and toxic materials, moistening skin and promoting granulation, and has the advantages of simple formula, no toxic or side effect, quick cure and no scar after cure.
Example 3
A traditional Chinese medicine for treating scalds and burns is prepared from the following raw materials in parts by weight: 290 parts of royal jelly, 105 parts of honey, 203 parts of propolis and 18 parts of bee hemolymph. The specific preparation method and the using method are the same as those of the example 2.
The traditional Chinese medicine for treating scalds and burns prepared by adopting the proportion and the method has the effects of quickly relieving pain, clearing away heat and toxic materials, moistening skin and promoting granulation, and has the advantages of simple formula, no toxic or side effect, quick cure and no scar after cure.
The formula of the traditional Chinese medicine for treating hemorrhoids provided by the embodiments 4 to 20 of the invention is shown in the table 1 to 2.
TABLE 1
Figure 495693DEST_PATH_IMAGE001
TABLE 2
Figure 412834DEST_PATH_IMAGE002
Clinical report
Clinically, 100 patients with burn were selected, including patients with second degree burn (dermal burn) and third degree burn (full thickness dermal burn), with a maximum burn area of 50%, and were immediately divided into two groups: fifty cases of each group, one group of the treatment groups applied with the Chinese traditional medicine of the invention in the embodiment 2, is an experimental group, and the other group of the treatment groups applied with the medicinal composition in the patent of a medicinal composition for treating burn and the preparation method thereof (application No. 200610045266.3), is a control group. Wherein, the two groups of patients have no obvious difference in age, burn area and depth, and the wound healing time of the two groups of patients is observed, and the results are shown in table 3.
TABLE 3
Figure 130254DEST_PATH_IMAGE003
Note: p is less than 0.05 when comparing the experimental group with the control group.
From the comparison of the results, it can be seen that the healing time of the injured part of the traditional Chinese medicine (experimental group) in the embodiment 2 of the invention is obviously shortened when the traditional Chinese medicine is used for treating burns and scalds, and the healing time is better than that of the control group.
The following are some typical cases:
when the patient is aged 26 years old and burned by fire on two hands, the burned area is 7 percent, the patient is shallow II degree, and the patient can be cured after being coated with the traditional Chinese medicine prepared in the embodiment 2 of the invention for 4 days without scars.
If a male, 3 years old, fell down and sit in a hot water basin when walking, the hip, the thigh and the waist are scalded, the scald area is 48%, and the wound part is completely healed after 14 days of coating by using the traditional Chinese medicine prepared in the embodiment 2 of the invention.
Wangzhi, female, 51 years old, burned arms with hot oil when cooking, burned area 6%, deep II degree, and injured parts were all healed after 15 days of coating with the traditional Chinese medicine prepared in the embodiment 2 of the invention.
In the case of a senior male, 38 years old, when the legs were scalded by sulfuric acid in a chemical experiment, the scalded area was 8%, and the superficial III degree, and the injured parts were all healed 22 days after being coated with the traditional Chinese medicine prepared in example 2 of the present invention.
The back, the hip, the lower limbs and the feet of a woman in age of 45 and a worker in a chemical plant are burnt by concentrated sulfuric acid due to an accident, the scald area is 16 percent, the superficial III degree is reached, and the injured part is completely healed after the traditional Chinese medicine prepared in the embodiment 2 of the invention is used for coating for 24 days.
After the left-aged man is aged for 35 years, and workers in construction sites are shocked to the five fingers of the right hand and the depth II degrees because of careless electricity, the injured parts are all healed after being coated with the traditional Chinese medicine prepared in the embodiment 2 of the invention for 16 days.
Wangzhi, female, 31 years old, burned hands and forearms with liquefied gas, burned area 10%, deep II degree, and the injured parts were all healed after 14 days of coating with the Chinese medicine prepared in the invention example 2.

Claims (3)

1. The traditional Chinese medicine for treating scalds and burns is characterized by being prepared from the following raw materials in parts by weight: 320 portions of royal jelly 280, 90 to 110 portions of honey, 220 portions of propolis 180 and 18 to 22 portions of bee hemolymph.
2. The traditional Chinese medicine for treating scalds and burns as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 300 parts of royal jelly, 100 parts of honey, 200 parts of propolis and 20 parts of bee hemolymph.
3. The preparation method of the traditional Chinese medicine for treating scalds and burns according to any one of claims 1 to 2, which comprises the following steps:
(1) weighing the propolis in parts by weight, completely melting the propolis at 60-70 ℃, and stopping heating;
(2) when the temperature is reduced to 40-50 ℃, adding the royal jelly and the honey in parts by weight while stirring, and continuously stirring to mix;
(3) when the temperature is reduced to room temperature, the honey hemolymph with the weight parts is added while stirring, and the mixture is uniformly mixed to obtain the honey hemolymph.
CN201710494004.3A 2017-06-26 2017-06-26 A Chinese medicinal composition for treating scald and burn Expired - Fee Related CN107233360B (en)

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CN118286286A (en) * 2024-03-28 2024-07-05 孙春敏 Repairing paste

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1293042A (en) * 1999-10-19 2001-05-02 梁霭 Propolis honey and its preparation method
CN1899332A (en) * 2006-06-30 2007-01-24 王成传 Medicinal composition for treating burn and its preparing method

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JP2003520572A (en) * 1999-07-02 2003-07-08 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド Keratinocyte growth factor-2
CN101617785A (en) * 2009-08-17 2010-01-06 刘富海 Compound royal jelly food and preparing process thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1293042A (en) * 1999-10-19 2001-05-02 梁霭 Propolis honey and its preparation method
CN1899332A (en) * 2006-06-30 2007-01-24 王成传 Medicinal composition for treating burn and its preparing method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
蜂蜜汁治疗烧伤;《甘肃畜牧兽医》;19940115(第01期);23-24 *

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