CN104056257A

CN104056257A - Emulsifiable paste for treating acne

Info

Publication number: CN104056257A
Application number: CN201410286808.0A
Authority: CN
Inventors: 谢一泓; 黎丹戎
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-06-24
Filing date: 2014-06-24
Publication date: 2014-09-24
Anticipated expiration: 2034-06-24
Also published as: CN104056257B

Abstract

The invention relates to an emulsifiable paste for treating acne, which comprises the following raw materials by weight: 70-150 parts of ketoconazole, 70-150 parts of lincomycin, 1200-2400 parts of metronidazole, 300-1200 parts of moroxydine hydrochloride, 35-90 parts of viaminate, 5-20 parts of tretinoin, 200-350 parts of vitamin E, 80-200 parts of vitamin B6, 50-100 parts of lidocaine, 600-2000 parts of aloe extract product, 1000-2000 parts of coconut meat powder and 100-800 parts of collagen powder with molecular weight lower than 2KD. The emulsifiable paste has the advantages of antibacterial function, antifungal function and anti-virus function, can promote epidermal cell differentiation and shedding, epidermal cell proliferation and differentiation can be adjusted, cornification is avoided, sebum secretion is adjusted, the emulsifiable paste has the effects of relieving pain, relieving itching, mitigating pockmark and whitening skin, and can help luster recovery for skin.

Description

A kind of acne treatment emulsifiable paste

Technical field

The present invention relates to a kind of acne treatment emulsifiable paste, relate in particular to a kind of external used medicine for the treatment of facial acne and hands, foot fungus infection.

Background technology

Acne is a kind of chronic inflammatory disease dermatoses of pilosebaceous unit, is mainly apt to occur in teenager, very large to teen-age psychology and social influence.It is feature that pleomorphism skin lesion such as being apt to occur in facial acne, pimple, pustule, tuberosity is take in clinical manifestation; Mostly occur at face, breast and back, forehead is easily to send out position, and its pathogenic factor is a lot, and main cause is hypersteatosis, pilosebaceous duct obstruction, antibacterial infection and inflammatory reaction etc.The medicine of existing Acne treatment is because the ill reason of patient is different, complicated and it is individual heterogeneous to exist, and the cause of disease that medicine is treated is single, makes therapeutic effect not obvious.And some drugs is mercurous, with after can leave sequela, make skin blackout, there is side effect.

Summary of the invention

For overcoming the deficiencies in the prior art, the object of this invention is to provide the acne treatment emulsifiable paste that a kind of Acne treatment is effective, side effect is little.

For achieving the above object, the present invention is achieved through the following technical solutions:

An acne treatment emulsifiable paste, is mainly made by the raw material of following weight portion: 70～150 parts of ketoconazoles, 70～150 parts of lincomycins, 1200～2400 parts of metronidazoles, 300～1200 parts of moroxydine hydrochlorides, 35～90 parts of Viaminates, 5～20 parts of tretinoins, 00～350 part of vitamin E2,80～200 parts of vitamin Bies, 50～100 parts of lignocaine, 600～2000 parts of Aloe extracts, 1000～2000 parts, coconut meat powder, 100～800 parts of the collagen protein powders below molecular weight 2KD.

In its Raw, also comprise adjuvant, the percentage ratio that adjuvant accounts for gross weight is 68.5%～87.6%.

Described adjuvant is comprised of the raw material of following percentage by weight: white vaseline 5%～15%; Octadecanol 5%～15%; Glyceryl monostearate 3%～10%; Glycerol 5%～15%; Peregal-O1.5%～2.5%; Chlorhexidine acetate 0.05%～0.15%; Dimethyl sulfoxide 1.5%～5%; Light liquid petrolatum 3%～10%; All the other are purified water.

Medicament selection ketoconazole of the present invention, lincomycin, metronidazole, moroxydine hydrochloride, Viaminate, tretinoin, vitamin E, vitamin B6, lignocaine, Aloe extract, coconut meat powder, collagen protein powder combine, these drug regimens make each efficacy of drugs produce synergism, thereby effectively Acne treatment, makes skin recover moist.Wherein:

Moroxydine hydrochloride: suppress viral DNA and RNA polymerase, thereby suppress virus breeding;

Metronidazole: anaerobe is had to killing action, disturb antibacterial growth, breeding, finally cause antibacterial dead;

Ketoconazole: dermophyte, yeast, dimorphic fungus and Mycophytes are had to antibacterial and bactericidal action;

Lincomycin: mainly gram positive bacteria is had to higher antibacterial activity, mechanism of action is synthetic for suppressing bacterium protein;

Viaminate: promote epithelial cell differentiation and come off, regulate and prevent keratinization, suppress sebum secretion, suppress the growth of propionibacterium acnes, antiinflammatory action;

Tretinoin: promote epidermis cell to upgrade, regulate epidermal cell proliferation and differentiation, make corneocyte loosen and easily come off, be conducive to remove acne, and suppress new acne formation;

Vitamin E: anti-oxidation protection skin, desalination pigmentation, whitening, anti-light aging, improve local blood supply;

Vitamin B6: regulate sebaceous gland, reaction reduces inflammation;

Lignocaine: antalgesic-antipruritic;

Aloe extract: sterilization, antiinflammatory, eases the pain and pruritus, makes skin contraction, improves the effect of pockmark, can whitening, defying age;

Coconut meat powder: antioxidation, defying age, whitening function;

Collagen protein powder (molecular weight 2KD is following): moisturizing, whitening, wrinkle resistant, be conducive to wound healing and scar repairing.

Compared with prior art, the invention has the beneficial effects as follows:

There is antibacterium, antifungal, antiviral, promote epidermis cell differentiation and come off, regulate epidermal cell proliferation and differentiation, prevent keratinization, regulate sebum secretion, and there is antalgesic-antipruritic, alleviate pockmark, the effect of whitening, help skin to recover gloss.Through clinical practice, remarkable to Acne treatment and tinea manus and pedis effect, generally application medicine of the present invention can obviously alleviate for 3 months, and therapeutic effect is obvious, is the ideal medicament of Acne treatment and tinea manus and pedis.

The specific embodiment

Below the present invention is described in detail, but should be noted that enforcement of the present invention is not limited to following embodiment.

The consumption of drug component of the present invention is also groped in a large number to sum up through inventor and is drawn, each amounts of components for all having good therapeutic effect within the scope of following weight parts:

Adjuvant heating in water bath is dissolved, then add all the other raw materials to mix, stir and can use, during use, be directly coated with affected part, 2～3 times/day.

Embodiment 1 (best proportioning)

Acne treatment emulsifiable paste proportioning is ketoconazole 0.1g; Lincomycin 0.1g; Metronidazole 1.3g; Moroxydine hydrochloride 0.6g; Viaminate 0.05g; Tretinoin 0.01g; Vitamin E 0.35g; Vitamin B6 0.12g; Lignocaine 0.08g; Aloe extract 1g; Coconut meat powder 1g; Collagen protein powder 0.2g.Coordinate adjuvant, wherein containing dimethyl sulfoxide 0.9g; Chlorhexidine acetate 0.03g; White vaseline 3g; Octadecanol 2.1g; Glyceryl monostearate 1.5g; Light liquid petrolatum 2.1g; Glycerol 1.5g; Peregal-O0.6g; All the other are purified water.Above-mentioned raw materials heating in water bath mix and blend forms the acne treatment emulsifiable paste of 30g.

Embodiment 2

Acne treatment emulsifiable paste proportioning is ketoconazole 0.07g; Lincomycin 0.07g; Metronidazole 1.2g; Moroxydine hydrochloride 0.3g; Viaminate 0.035g; Tretinoin 0.005g; Vitamin E 0.2g; Vitamin B6 0.08g; Lignocaine 0.05g; Aloe extract 0.6g; Coconut meat powder 1g; Collagen protein powder 0.1g.Adjuvant is containing dimethyl sulfoxide 0.5g; Chlorhexidine acetate 0.024g; White vaseline 1.8g; Octadecanol 1.8g; Glyceryl monostearate 1.2g; Light liquid petrolatum 2.4g; Glycerol 3g; Peregal-O0.54g; All the other are purified water.Above-mentioned raw materials heating in water bath mix and blend forms the acne treatment emulsifiable paste of 30g.

Embodiment 3

Acne treatment emulsifiable paste proportioning is ketoconazole 0.15g; Lincomycin 0.15g; Metronidazole 2.4g; Moroxydine hydrochloride 1.2g; Viaminate 0.09g; Tretinoin 0.02g; Vitamin E 0.35g; Vitamin B6 0.2g; Lignocaine 0.1g; Aloe extract 2g; Coconut meat powder 2g; Collagen protein powder 0.8g.Coordinate adjuvant, wherein containing dimethyl sulfoxide 1.32g; Chlorhexidine acetate 0.036g; White vaseline 3.6g; Octadecanol 3g; Glyceryl monostearate 2.4g; Light liquid petrolatum 1g; Glycerol 2g; Peregal-O0.66g; All the other are purified water.Above-mentioned raw materials heating in water bath mix and blend forms the acne treatment emulsifiable paste of 30g.

The clinical observation of Drug therapy acne of the present invention:

So-and-so, female, 25 years old, patients with acne, grain of rice size acne spreads all over face and forehead (facial skin lesion reaches 80%), uses acne treatment emulsifiable paste 6 months, reaches completely and cure (obviously to alleviate 3 months time, in the time of 6 months, cure completely), and do not stay pigmentation, skin recovery effects is good, white and fine and smooth, used respectively vitamin E class, the external used medicine effects such as tretinoin are all not obvious before.

Certain so-and-so, man, 21 years old, patients with acne, buccal portion acne merges in flakes, and color is red, and face goes out Chuck Steak.Use acne treatment emulsifiable paste 7 months, reach completely and cure.

So-and-so, female, 32 years old, patients with acne, buccal and acne frontalis, the tenderness of touching, pruritus, color is red.Use acne treatment emulsifiable paste 5 months, reach completely and cure.Non-pigment is calm, the white and smooth exquisiteness of skin.

Opponent of the present invention, tinea pedis also have certain curative effect:

Certain so-and-so, female, 41 years old, hands, tinea pedis patient, both hands and biped all infect, and blister is transparent as brilliant, and pruritus is unbearably.Use acne treatment emulsifiable paste 3 months, the state of an illness obviously alleviates, 5 months basic healings.

So-and-so, man, 65 years old, tinea pedis patient, between toe, repeatedly there is the large exanthema vesiculosum of syringe needle in the sufficient sole of the foot and lateral margin thereof, assembles or be dispersed in, pruritus, has desquamation.Use acne treatment emulsifiable paste 3 months, the state of an illness obviously alleviates, 6 months basic healings.

The present invention has the effects such as antibacterium, antifungal, antiviral, has the differentiation of the epidermis cell of promotion and comes off, and regulates epidermal cell proliferation and differentiation, prevent keratinization, regulate sebum secretion, and there is antalgesic-antipruritic, alleviate pockmark, the effect of whitening, help skin to recover gloss.Through clinical practice, remarkable to Acne treatment and tinea manus and pedis effect, generally application medicine of the present invention can obviously alleviate for 3 months, and therapeutic effect is obvious, is the ideal medicament of Acne treatment and tinea manus and pedis.

Claims

1. an acne treatment emulsifiable paste, it is characterized in that, mainly by the raw material of following weight portion, made: 70～150 parts of ketoconazoles, 70～150 parts of lincomycins, 1200～2400 parts of metronidazoles, 300～1200 parts of moroxydine hydrochlorides, 35～90 parts of Viaminates, 5～20 parts of tretinoins, 00～350 part of vitamin E2,80～200 parts of vitamin Bies, 50～100 parts of lignocaine, 600～2000 parts of Aloe extracts, 1000～2000 parts, coconut meat powder, 100～800 parts of the collagen protein powders below molecular weight 2KD.

2. a kind of acne treatment emulsifiable paste according to claim 1, is characterized in that, also comprises that the percentage ratio that adjuvant, adjuvant account for gross weight is 68.5%～87.6% in its Raw.

3. a kind of acne treatment emulsifiable paste according to claim 2, is characterized in that, described adjuvant is comprised of the raw material of following percentage by weight: white vaseline 5%～15%; Octadecanol 5%～15%; Glyceryl monostearate 3%～10%; Glycerol 5%～15%; Peregal-O1.5%～2.5%; Chlorhexidine acetate 0.05%～0.15%; Dimethyl sulfoxide 1.5%～5%; Light liquid petrolatum 3%～10%; All the other are purified water.