CN105030813B - A kind of compound preparation for being used to treat sheep mouth inflammation - Google Patents
A kind of compound preparation for being used to treat sheep mouth inflammation Download PDFInfo
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- CN105030813B CN105030813B CN201510392966.9A CN201510392966A CN105030813B CN 105030813 B CN105030813 B CN 105030813B CN 201510392966 A CN201510392966 A CN 201510392966A CN 105030813 B CN105030813 B CN 105030813B
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- compound preparation
- mouth inflammation
- sheep mouth
- inflammation
- sheep
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims abstract description 32
- 241001494479 Pecora Species 0.000 title claims abstract description 26
- 206010061218 Inflammation Diseases 0.000 title claims abstract description 22
- 230000004054 inflammatory process Effects 0.000 title claims abstract description 22
- 239000003814 drug Substances 0.000 claims abstract description 15
- 235000006533 astragalus Nutrition 0.000 claims abstract description 9
- 241001061264 Astragalus Species 0.000 claims abstract description 8
- 210000004233 talus Anatomy 0.000 claims abstract description 8
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 7
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 7
- BVGLIYRKPOITBQ-ANPZCEIESA-N benzylpenicillin benzathine Chemical compound C=1C=CC=CC=1C[NH2+]CC[NH2+]CC1=CC=CC=C1.N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1.N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)CC1=CC=CC=C1 BVGLIYRKPOITBQ-ANPZCEIESA-N 0.000 claims abstract description 7
- 229940116229 borneol Drugs 0.000 claims abstract description 7
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 7
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 7
- 229940099259 vaseline Drugs 0.000 claims abstract description 7
- 208000003265 stomatitis Diseases 0.000 abstract description 12
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 6
- 230000000840 anti-viral effect Effects 0.000 abstract description 4
- 230000000202 analgesic effect Effects 0.000 abstract description 3
- 230000029663 wound healing Effects 0.000 abstract description 3
- 210000000214 mouth Anatomy 0.000 description 15
- 206010052428 Wound Diseases 0.000 description 8
- 208000027418 Wounds and injury Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 208000005925 vesicular stomatitis Diseases 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 241000045403 Astragalus propinquus Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000588653 Neisseria Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010031009 Oral pain Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 239000010075 Qingdai compound Substances 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002052 anaphylactic effect Effects 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 201000005332 contagious pustular dermatitis Diseases 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000004459 forage Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000001114 myogenic effect Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A kind of compound preparation for being used to treat sheep mouth inflammation, often contains following medicine in the compound preparation of 1000.0g：Vaseline 900.0-920.0g；70% astragalus polyose 40.0-60.0g；Tardocillin 30.0-40.0g；Borneol 4.0-6.0g.Compound preparation provided by the invention has the advantages that efficient, antiviral, antibacterial, analgesic, stimulates small, easy to use, nonpollution environment.The compound preparation can speed up sheep mouth inflammation wound healing, shorten stomatitis treatment time.In addition, this compound preparation have the characteristics that materials easily, prepare it is easy, of low cost, using easy to operate, be a kind of compound preparation of preferably treatment sheep mouth inflammation.
Description
Technical field
The present invention relates to the compound preparation for the treatment of sheep mouth inflammation, specifically a kind of compound system for being used to treat sheep mouth inflammation
Agent.
Background technology
Sheep mouth inflammation is more due to wound or infectious disease（Such as sore mouth virus, aftosa, sheep pox, mycotic stomatitis）Cause；Easily lead
Sheep feeding is caused to reduce or give up absolutely, it is very harmful to sheep husbandry.Treatment sheep mouth inflammation was generally using 0.1% potassium permanganate, 2% iodine in the past
Tincture, 10% saline solution, 3% boric acid aqueous solution etc. rinse the surface of a wound repeatedly, then smear jodine glycerin etc..This kind of medicine is to mucocutaneous
Irritation is larger, and operation is cumbersome, and particularly clinically sheep jumpbogroup is fallen ill in use, time consuming.At present, sheep mouth inflammation is treated
Use Chinese patent drug qingdai powder for animals or Bingpeng San, method in clinical application is to rinse inflammation surface of a wound after-blow to spread affected part, 2-3 on the one more
It is secondary, continuous 3-5 days.Due to being powder, it is be easy to cause when to sheep oral cavity medicine and spills loss, and disposable dosage is larger,
Medical expense is higher.
The content of the invention
It is an object of the invention to provide a kind of compound preparation for being used to treat sheep mouth inflammation, which is directly applied to
On the surface of a wound of sheep mouth inflammation, the healing of ulcer wound surface can be accelerated, to shorten stomatitis treatment time.
To achieve the above object, the present invention uses following scheme：A kind of compound preparation for being used to treat sheep mouth inflammation, often
Contain following material medicine in the compound preparation of 1000.0g：Vaseline 910.0-920.0g；70% astragalus polyose 40.0-
60.0g；Tardocillin 30.0-40.0g；Borneol 4.0-6.0g.
In compound preparation provided by the invention, the effect of each material medicine, is as follows：
Vaseline, is faint yellow or yellow homogeneous soft paste, odorless, without any additive, is had with skin contact
Satiny sensation, has certain stringiness, is widely used in field of medicaments.Do not absorbed for skin outside vaseline,
It can lubricate and softening skin, mucous membrane, mitigation external irritant, a mechanicalness protective effect.
Astragalus polyose, is legume astragalus mongolicus or Astragalus membranaceus extract, and astragalus polyose is that radix astragali plays a role
Main component.Radix astragali has the effect of invigorating qi for consolidating superficies, torr sore myogenic, inducing diuresis for removing edema, plays the role of antibacterial, antiviral, clinically leads
It is used to treat the diseases such as ulcer is difficult to burst, burst for a long time and does not holds back.
Tardocillin, tardocillin absorption is extremely slow, and blood concentration is low, is grown using interval；In the bacterial reproduction phase
Play bactericidal effect, to gram-positive cocci (streptococcus, pneumococcus, sensitivity staphylococcus) and Gram-negative coccus
The antibacterial action of (meningococcus, gonococcus) is stronger.
Borneol, is mainly used for closing disease coma, red eye, swell pain, larynx numbness aphtha, sore swell and ache curative, the disease such as does not hold back after bursting.Borneol stops
Pain positive effect, can accelerate inflammation to eliminate, and promote lesion oral mucosa to strip off, rotten to the corn and ulcer healing.
Compound preparation provided by the invention has efficient, antiviral, antibacterial, analgesic, stimulation is small, easy to use, pollution-free
The advantages that environment.The compound preparation can speed up sheep mouth inflammation wound healing, shorten stomatitis treatment time, in addition, this compound preparation
Have the characteristics that materials easily, prepare it is easy, of low cost, using easy to operate.
Embodiment
The present invention is further illustrated below in conjunction with an embodiment.
Embodiment
Contain following medicine in compound preparation provided in this embodiment per 1000.0g：Vaseline 910.0g；70% is yellow
Astragalus polysaccharides 50.0g；Tardocillin 35.0g；Borneol 5.0g.Above material medicine is uniformly mixed in appropriate container, to obtain the final product
This compound preparation.
The suggested use and dosage of compound preparation provided by the invention is：1st, the sick sheep of catarrhal stomatitis and vesicular stomatitis can use
Absorbent-cotton rod dips this compound preparation Direct Uniform and is applied on the surface of a wound, one time a day, continuous 3 times.2nd, stomacace, can first use
After physiological saline rinses the surface of a wound repeatedly, then dip this compound preparation Direct Uniform with absorbent-cotton rod and be applied on the surface of a wound, one time a day,
It is 3-5 times continuous.
It should be noted that following item before medication：
1st, it is fed for softness and is rich in the digestible forage of nutrition.
2nd, having to this compound preparation anaphylactoid should stop using.
3rd, when sick sheep suffers from stomatitis and occur together severe bacterial infections when, can be used in combination antibiotic carry out whole body therapeutic.
The therapeutic effect of compound preparation provided by the invention is further illustrated below in conjunction with curative effect evidence.
Clinical Treatment Test：The model case of selection infection sheep mouth inflammation is treated, and method is by upper by this compound preparation
Method is stated, point catarrhal stomatitis or vesicular stomatitis and stomacace evaluate therapeutic effect after using according to regulations.
Sheep mouth inflammation case therapeutic test result
| Animal | Before medication（Head） | After medication effectively（Head） | Invalid or weak effect after medication（Head） | Cure rate（%） |
| Catarrhal stomatitis or vesicular stomatitis | 114 | 107 | 7 | 93.86 |
| Stomacace | 38 | 32 | 6 | 84.21 |
As it can be seen that compound preparation provided by the invention has efficient, antiviral, antibacterial, analgesic, stimulates small, easy to use, nothing
The advantages that polluting environment.The compound preparation can speed up sheep mouth inflammation wound healing, shorten stomatitis treatment time.In addition, this compound
Preparation have the characteristics that materials easily, prepare it is easy, of low cost, using easy to operate, be a kind of preferably treatment sheep mouth inflammation
Compound preparation.
Claims (2)
1. a kind of compound preparation for being used to treat sheep mouth inflammation, it is characterised in that by following original in the compound preparation per 1000.0g
Expect medicine composition：Vaseline 900.0-920.0g；70% astragalus polyose 40.0-60.0g；Tardocillin 30.0-40.0g；
Borneol 4.0-6.0g.
2. the compound preparation according to claim 1 for being used to treat sheep mouth inflammation, it is characterised in that this per 1000.0g is multiple
It is made of in square preparation following material medicine：Vaseline 910.0g；70% astragalus polyose 50.0g；Tardocillin 35.0g；Borneol
5.0g。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510392966.9A CN105030813B (en) | 2015-07-07 | 2015-07-07 | A kind of compound preparation for being used to treat sheep mouth inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510392966.9A CN105030813B (en) | 2015-07-07 | 2015-07-07 | A kind of compound preparation for being used to treat sheep mouth inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105030813A CN105030813A (en) | 2015-11-11 |
| CN105030813B true CN105030813B (en) | 2018-05-01 |
Family
ID=54438178
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510392966.9A Active CN105030813B (en) | 2015-07-07 | 2015-07-07 | A kind of compound preparation for being used to treat sheep mouth inflammation |
Country Status (1)
| Country | Link |
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| CN (1) | CN105030813B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111407791A (en) * | 2020-03-16 | 2020-07-14 | 鄂州职业大学 | External traditional Chinese medicine care solution for promoting wound healing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083322A (en) * | 2014-07-27 | 2014-10-08 | 李仲昆 | Astragalus polysaccharide gel |
| CN104306757A (en) * | 2014-09-28 | 2015-01-28 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition for preventing and treating sheep stomatitis and preparation method thereof |
-
2015
- 2015-07-07 CN CN201510392966.9A patent/CN105030813B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083322A (en) * | 2014-07-27 | 2014-10-08 | 李仲昆 | Astragalus polysaccharide gel |
| CN104306757A (en) * | 2014-09-28 | 2015-01-28 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition for preventing and treating sheep stomatitis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 一起羊传染性脓口疮诊治的报告;庞君清;《养殖技术顾问》;20131231;第152页 * |
| 复方黄芪多糖防制病毒性口炎的初步效果;吕文江;《养殖技术顾问》;20070831;第98页 * |
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| Publication number | Publication date |
|---|---|
| CN105030813A (en) | 2015-11-11 |
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Effective date of registration: 20240229 Address after: 233100 Intersection of Renai Road and Shejitan Road, Fucheng Town, Fengyang County, Chuzhou City, Anhui Province Patentee after: Fengyang County Economic Development Investment Co.,Ltd. Country or region after: China Address before: 233100 Donghua Road, Fengyang County, Chuzhou City, Anhui Province Patentee before: ANHUI SCIENCE AND TECHNOLOGY University Country or region before: China |
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