CN1126563C - Exterior-applied medicine for treating acne - Google Patents
Exterior-applied medicine for treating acne Download PDFInfo
- Publication number
- CN1126563C CN1126563C CN 01133504 CN01133504A CN1126563C CN 1126563 C CN1126563 C CN 1126563C CN 01133504 CN01133504 CN 01133504 CN 01133504 A CN01133504 A CN 01133504A CN 1126563 C CN1126563 C CN 1126563C
- Authority
- CN
- China
- Prior art keywords
- acne
- present
- treatment
- medicine
- cured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to an externally applied medicine for treating acne, which belongs to a traditional Chinese medicament with traditional Chinese medicines as raw materials. The medicinal ingredients comprise dried alum, realgar, sulfur, litharge, typhonii and white vinegar. The present invention carries out treatment of acne through the synergistic effects of the ingredients based on the principles of dissipating blood stasis, killing germs, detoxicating and beautifying face of Chinese medicines. The externally applied medicine for treating acne has the advantages of simple use, stable curative effect and no recurrence. Mild acne can be cured in about 30 days, moderate acne can be cured in about 45 days, and severe acne can be cured in about 60 days. Through clinical observation of 100 cases of acne patients, the effective rate of the present invention reaches 100%, and the cure rate reaches 97%. The present invention solves the problems of long treatment time, not obvious curative effect, easy recurrence and side effect on human bodies of the existing medicines for treating acne. The present invention is suitable for the treatment of the acne of various types.
Description
The present invention relates to a kind of is the medicine for external use that preparation of raw material forms with Chinese medicine, is exclusively used in remedy of acne.
Acne (acne, vulgaris) claims " comedo ", " skin sore ", " whelk " again, is a kind of with the chronic pilosebaceous unit inflammation of obstructive multifactor, that the pleomorphism erythra is feature.Primary disease is the facial common a kind of dermatosis of adolescence.This disease starts from adolescence, so be more common in youth of both sexes, the women generally falls ill Zao than the male, and the male is generally heavy than the women state of an illness, good sending out in face, the more rich position of chest and back sebaceous gland.With acne, pimple, pustule, tuberosity, cyst and cicatrix is feature.Basic infringement is acne, and acne are in the disease progression process, and owing to the struvite little pimple of hair follicle takes place bacterial infection, the heavier person of inflammation can form sclerancne.The acne that have can develop into the softish acne cystica of character, and the most serious is acne conglobata, form cicatrix, the influence beauty treatment, and severe patient can be disfeatured.
Clinically to the treatment of seat skin ulcer.(1) general treatment: mainly be the attention of requirement patient aspect diet, the diet of promptly edible low fat, low sugar, homovitamin also adopts medicine to correct constipation, is aided with and uses the warm water, and neutral soap washes one's face.But this Therapeutic Method can only play the formation of prevention acne or light disease acne is played auxiliary treatment.Use above-mentioned Therapeutic Method curative effect very little clinically.(2) to the non-inflammation remedy of acne: mainly be to use retinoid compounds,, or adopt antiandrogen class medicine, as spironolactone etc. as Accutane etc.
The treatment of above-mentioned two class medicines can reach the purpose of eliminating acne and preventing or reduce new acne formation, but the treatment time of retinoid compounds is long, generally wanted for 16 weeks, and take the back, and curative effect not very stable with side effect such as cheilitis and xerosis cutiss.Though the antiandrogen class Drug therapy time is shorter, be generally 1 month oral medicine 20 days, three months is a course of treatment, but can not thoroughly cure a course of treatment, and drug withdrawal is easily recurred, and after this type of medicine took for a long time, to human body produce electrolysis matter disorder and the side effect of gonadal hormone sample, renal function bad person can not use.(3) to struvite remedy of acne: mainly adopt medicine and employing 17-hydroxy-11-dehydrocorticosterone such as antibiotic, erythromycin, spiramycin, tetracycline, metronidazole, promptly disease is decreased position injection Adcortyl-A suspension, this method only is suitable for capsule or acne conglobata.
But this kind treatment is except that the side effect that antibiotic itself is arranged, and acne is only prevented from the effect of new struvite infringement from can not directly act on a skin ulcer.And 17-hydroxy-11-dehydrocorticosterone also only is used for the local injection treatment of capsule or acne conglobata.(4) local treatment: mainly be the sulfur frost that adopts external, sulfur lotion, Xi Ersheng solution, U-21251 skin sore water etc.
Though but the medicine for external use of local treatment has certain curative effect in use, unstable, in case drug withdrawal, very easily recurrence.
The application of comprehensive above-mentioned various Therapeutic Method and various medicines requires the differentiation of user to the state of an illness, correct judgment, and medication is adjusted in conversion in good time, notes also side effects of pharmaceutical drugs, and this is difficult to accomplish to general patient, and treatment back effect instability.
The objective of the invention is, providing a kind of mainly is at the various acnes of facial area, can be antibacterial, the medicine for external use of the treatment acne of convergence, dissipating blood stasis, parasite killing, detoxifcation, skin care, and treatment is simplified, thoroughly cure, be difficult for recurrence.
The present invention proposes according to the principle of the dissipating blood stasis of the traditional Chinese medical science, parasite killing, detoxifcation, skin care.Be based on pathogenetic research and the Therapeutic Principle of motherland's medical science,, press the tcm theory prescription with reference to the scientific achievement of modern pharmacological research to the treatment by Chinese herbs acne to acne, skim the cream off milk by prescription handed down from one's ancestors, the break traditions taboo of medication is screened from common Chinese, meticulously preparation.Medicine among the present invention: dried Alumen has the effect of dampness, hemostasis, detoxifcation, parasite killing; Sulfur has the effect of parasite killing, dissolving cutin; Realgar has the effect of dampness, parasite killing, detoxifcation; The Lithargyrum has detumescence, parasite killing, the anticorrosion effect of convergence; Rhizoma Typhonii have dispel the wind, by the effect trembling with fear, brighten; White vinegar has the effect of dissipating blood stasis, hemostasis, detoxifcation parasite killing, clean skin.Behind prescription, make it produce good synergism, through clinical observation, it has the comprehensive function of antibacterial, antiinflammatory, convergence, dissipating blood stasis, parasite killing, detoxifcation, skin care, makes the curable purpose of acne and reach.
Medicine of the present invention is the medicament of being made by the following weight proportion raw material:
Dried Alumen 4.61%-6.06%
Realgar 4.61%-6.06%
Sulfur 4.61%-6.06%
Lithargyrum 3.94%-4.85%
Rhizoma Typhonii 3.28%-4.24%
White vinegar 72.73%-78.95%
The optimum weight proportioning of medicine of the present invention is:
Dried Alumen 5.36%
Realgar 5.36%
Sulfur 5.36%
The Lithargyrum 4.42%
Rhizoma Typhonii 3.79%
White vinegar 75.71%
Above-mentioned each component by conventional preparation method, that is: according to the above ratio, with dried Alumen, Realgar, sulfur, Lithargyrum, Rhizoma Typhonii, is ground into fine powder, crosses 120 mesh sieves, again white vinegar is poured in the blended medicated powder, stir into yellow suspension, get product.
Clinical drug of the present invention uses the result to show that have following advantage: medication is single, and is easy to use, instant effect, and good effect does not recur.
In order to show the present invention to treatment remedy of acne effect, the present invention passes through the system's clinical observation to 100 routine acne patients, and according to " modern skin cypridology " Cunliffc of Wu Zhihua chief editor acne is divided into three grades, and 1. slight acne is based on acne; 2. moderate acne, with the inflammatory pimple, pustule is main; 3. severe acne is based on tuberosity and struvite cyst.Select medical history, the state of an illness, age, sick time, to the observed result of its curative effect as described in following table one, the table two.
Table one: treatment side and to the comparative result (being the result who carries out clinical control with 60 routine moderate acnes in 100 examples in the table) of analogy treatment acne
| Use medicine | Effective time (my god) | Healing time (my god) | The case number | Cure rate |
| Medicine for external use of the present invention | 7 | 45-50 | 60 | 98％ |
| External 5% sulfur frost adds the oral tetracycline sheet | 12 | 55-60 | 60 | 93％ |
Table two: use the therapeutic effect of medicine for external use of the present invention to 100 routine acne patients
| Classification | Sick time | State of an illness weight | Age | |||||
| The case number | 60 people in 2 years | 40 people more than 2 years | Light 20 people | In 60 people | Weigh 20 people | 13 years old-25 years old 45 people | 25 years old-30 years old 35 people | 20 people more than 30 years old |
| Cure number | 60 | 38 | 20 | 59 | 19 | 44 | 34 | 19 |
| Cure rate | 100％ | 95％ | 100％ | 98％ | 95％ | 98％ | 97％ | 95％ |
The using method of medicament of the present invention:
Clean before the medication facially, then this medicinal liquid shaken up, dip in this medicinal liquid with cotton swab and embrocate the acne position, clean about 12 hours facial, the preceding use of can once-a-day sleeping at night, or a twice-daily early, use evening.30 days is a course of treatment, and slight acne is cured a course of treatment; The moderate acne is cured 1 half course of treatment; Severe acne is cured two courses of treatment.
Model case:
Case one: Lee * *, man, 14 years old, the student grows the granular pale red erythra of foxtail millet in July, 1996 because of two cheek, goes to a doctor the year before, face does not have pain, and idol has gargalesthesia, and other position does not have similar erythra, going to a doctor preceding is " comedo " at city's dermatosis hospital diagnosis, with " sulfur frost " external, and poor effect, use fashion, the time spent does not recur again, after use " erythromycin ointment ", " topsyne ointment ", " PIYANPING " etc. again voluntarily, poor effect.Also be diagnosed as " slight acne " in here,, use once before sleeping every night with medicine external of the present invention, the back further consultations of 2 weeks, cheek portion erythra obviously reduces, no any discomfort, erythra disappearance position skin has shown normal color.4 week back patient further consultations once more, erythra disappears fully, and face has recovered normal color.Follow up a case by regular visits to and do not have recurrence so far.
Case two: Liu * *, the woman, 19 years old, the public relation girl, in May, 1991 because of the long red pimple of two cheek and forehead and pimple 2 years, come to go to a doctor.There are pain and gargalesthesia in face, and other position does not have similar pimple and pustule, heavily with regard to symptom before the rash and does not note, likes again squeezing with hands, develops into buccal and forehead afterwards, and more and more, oneself also once uses externals such as " PIYANPING ", " topsyne " invalid.The back is controlled to Shenzhen's dermatosis hospital rash, be diagnosed as " acne ", oral with " tetracycline tablet ", each 0.25g, 4 times on the one, external 5% sulfur frost, medication curative effect to some extent after 20 days, but malaise symptoms such as abdominal distention occurs, feel sick considers it is the side effect of tetracycline, patient stop using " tetracycline " and medicine for external use, thereafter state of an illness outbreak repeatedly again, and more and more serious, begin to have pain and gargalesthesia, and long pimple, go to a doctor in the here of coming out of admiration for a famous person, be diagnosed as " moderate acne " in here with medicine external of the present invention, a twice-daily, early, use evening.3 week back further consultations, not bitterly, do not itched, pustule has not had yet, and " small pox " also disappeared much.Advise patient's preceding use of only need once-a-day sleeping specifically, 3 week back patients call " small pox " do not had entirely, the present very self-confident public relations cause of doing her is followed up a case by regular visits to and is not had recurrence so far.
Below producing of medicine for external use of the present invention lifted a specific embodiment
To produce 1000 kilograms medicament is example
Take by weighing raw material (kilogram) by following proportioning
Dried Alumen 5.36%
Realgar 5.36%
Sulfur 5.36%
The Lithargyrum 4.42%
Rhizoma Typhonii 3.79%
White vinegar 75.71%
Get 53.6 kilograms of dried Alumens, 53.6 kilograms of Realgars, 53.6 kilograms in sulfur, 44.2 kilograms of Lithargyrums, 37.9 kilograms of Rhizoma Typhoniis, 757.1 kilograms of white vinegars.
With 53.6 kilograms of dried Alumens, 53.6 kilograms of Realgars, 53.6 kilograms in sulfur, 44.2 kilograms of Lithargyrums, 37.9 kilograms of Rhizoma Typhoniis, pulverize is crossed 120 mesh sieves, mixes for 757.1 kilograms with white vinegar then earlier, stir about 2 minutes, after making solution be yellow, be finished product, bottled standby.
Claims (2)
1. medicine for external use for the treatment of acne is characterized in that it is made up of following components in weight percentage:
Dried Alumen 4.61%-6.06%
Realgar 4.61%-6.06%
Sulfur 4.61%-6.06%
Lithargyrum 3.94%-4.85%
Rhizoma Typhonii 3.28%-4.24%
White vinegar 72.73%-78.95%
2. a kind of medicine for external use for the treatment of acne according to claim 1 is characterized in that it is made up of following components in weight percentage:
Dried Alumen 5.36%
Realgar 5.36%
Sulfur 5.36%
The Lithargyrum 4.42%
Rhizoma Typhonii 3.79%
White vinegar 75.71%
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133504 CN1126563C (en) | 2001-09-26 | 2001-09-26 | Exterior-applied medicine for treating acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133504 CN1126563C (en) | 2001-09-26 | 2001-09-26 | Exterior-applied medicine for treating acne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1346665A CN1346665A (en) | 2002-05-01 |
| CN1126563C true CN1126563C (en) | 2003-11-05 |
Family
ID=4671868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01133504 Expired - Fee Related CN1126563C (en) | 2001-09-26 | 2001-09-26 | Exterior-applied medicine for treating acne |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1126563C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199703B (en) * | 2007-12-12 | 2010-12-15 | 叶志军 | Tincture medicament for treating acne |
| US8349372B1 (en) * | 2010-03-12 | 2013-01-08 | Seth Lowell | Composition for the prevention and treatments of acne and oily skin |
| CN102670926B (en) * | 2012-03-19 | 2014-04-02 | 苏甲臣 | Medicine for treating acne |
-
2001
- 2001-09-26 CN CN 01133504 patent/CN1126563C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1346665A (en) | 2002-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108992451A (en) | A kind of emulsifiable paste and preparation method thereof with anti-inflammatory anti-itch antibiotic effect | |
| CN101313940B (en) | Traditional Chinese medicine nourishing skin-protection cream | |
| CN1126563C (en) | Exterior-applied medicine for treating acne | |
| CN103599455B (en) | Traditional Chinese medicine capsule for removing freckle | |
| CN103768357B (en) | A kind of Traditional Chinese medicine compound composition with treatment recurrent aphtha | |
| CN1116038C (en) | Exterior-applied liquid medicine for treating acne | |
| CN1381259A (en) | Medicine for treating diseases of rectum and anus | |
| CN1331983A (en) | Hyperosteogeny treating medicine | |
| JPH10114665A (en) | Improver for aqueous body fluid and composition for oral administration comprising the same | |
| CN1309402C (en) | Chinese drug for treating cholecystitis | |
| CN102266408B (en) | Use of gardenia extract and borneol effective ingredients in Chinese medicine preparation for intervening in cutaneous prutitus | |
| CN105168360A (en) | Compound plant extract liniment for treating acne and preparation method of compound plant extract liniment | |
| CN1140289C (en) | Gynopathy treating Chinese medicine with functions of diminishing inflammation and eliminating spot and its prepn | |
| CN101185695B (en) | Externally-applied traditional Chinese medicine for treating toothache | |
| Teoh et al. | Comprehension and experience of acne treated with traditional chinese medicine facial mask of bai zhi (Radix Angelicae Formosanae) and bai fu zi (Rhizoma Typhonii Gigantei) as the basis formula by external application | |
| CN1247227C (en) | External-use liposome prepn for treating mite-borne dermatosis | |
| CN1169567C (en) | Medicine for external application for curing infantile pneumonia and preparing method thereof | |
| CN1562117A (en) | Chinese medicinal preparation for quick bone fracture setting | |
| CN106309926A (en) | Composition prepared from bee products and medical and edible dual-purpose food and used for treating gastritis and gastric ulcer | |
| Javed | Ayurvedic Management of Prurigo nodularis at scalp: A case report | |
| CN105434988A (en) | Traditional Chinese medicine composition for treating neurodermatitis | |
| CN106539817A (en) | For treating ointment, the preparation method and its usage of acne | |
| CN1256100C (en) | Artificial bear gall | |
| Lihua et al. | The Therapeutic Effect of Quyu Jiedu Xiaozheng Tang Combined with Diqu Progesterone Tablets on Endometriosis and Its Effect on Serum MIF and TGF-Β Impact Of 1 | |
| CN102283982B (en) | Medicinal composition for treating skin diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Ren Yingbin Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice |
Addressee: Ren Yingbin Document name: Notification of Termination of Patent Right |
|
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20031105 Termination date: 20091026 |