CN1631205A - Probiotic feed additive - Google Patents
Probiotic feed additive Download PDFInfo
- Publication number
- CN1631205A CN1631205A CNA2004100777064A CN200410077706A CN1631205A CN 1631205 A CN1631205 A CN 1631205A CN A2004100777064 A CNA2004100777064 A CN A2004100777064A CN 200410077706 A CN200410077706 A CN 200410077706A CN 1631205 A CN1631205 A CN 1631205A
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- powder
- thalline
- dry powder
- feed additive
- inserts
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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- Fodder In General (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The invention provides a Probiotic feed additive, which comprises Probiotic and filling agent, wherein the Probiolic can be single strain preparation, composite bacterial strain or the mixture of more than one single bacterial strain preparation, for example, the combination can be prepared by mixing bacillus subtilis powder, brewer's yeast dried powder and bacillus licheniformis dried powder. The filling agent comprises sea-tangle powder, bran flour and zeolite powder.
Description
Technical field
The present invention relates to a kind of feed addictive, relate in particular to a kind of prebiotics feed additive.
Background technology
Probiotic is the biologically active agents of being made by living microorganism, can be by the competitive exclusion effect of animal alimentary canal biology, suppress the growth of harmful mushroom, form dominant microflora or come prevent disease, thereby promote growth of animal and improve food conversion ratio by strengthening non-specific immune function.Prebiotics feed additive is nontoxic to livestock products, and the mankind are had no side effect, and is a kind of novel green feed addictive that grows up the nearly more than ten years.
The formulation of prebiotics feed additive has aqua and pulvis two big classes at present.The aqua formulation is generally single probio, and thalline utilizes the nutriment continued growth fermentation in the aqua easily, so the thalline of this formulation plays pendulum, storage life is short.The pulvis formulation is by means such as hot-air seasoning, freeze dryings thalline or gemma to be dewatered at a slow speed, makes thalline or gemma enter stable dry resting state, utilizes absorption thalline or gemma such as feed grade filler such as wheat bran, corn flour again.Because the holding time of pulvis is longer than aqua, thus on the market formulation of prebiotics feed additive based on pulvis, and mainly with wheat bran, rice bran, corn flour as inserts.
In addition in use, require prebiotics feed additive to possess certain performance of sticking, mix when stirring prebiotics feed additive being added in the animal-breeding feed, can be adsorbed on the animal-breeding feed, so that animal is got food.
Summary of the invention
The object of the present invention is to provide a kind of new prebiotics feed additive, it is stable that this feed addictive not only has thalline, the characteristics that the thalline time-to-live is long, and have certain performance of sticking.
The present invention evenly mixes probiotic with a certain proportion of sea-tangle powder, wheat bran and zeolite powder, obtain a kind of new prebiotics feed additive, the thalline of this additive is stable, and the thalline time-to-live is long, and obtained the good performance of sticking, thereby realized purpose of the present invention by the sea-tangle powder.
A kind of prebiotics feed additive of the present invention is characterized in that by mass ratio being that 1: 4～12 probiotic and inserts are formed, and described inserts is sea-tangle powder, wheat bran and the zeolite powder of mass ratio 10: 1～3: 1～2.
Described probiotic can be the mixture of single bacterial strain preparation, compound strain preparation or two or more single bacterial strain preparations, as single bacterial strain dry powder or its mixture of bacillus subtilis (Bacillus subtilis), brewer's yeast (Saccharomyces cerevisiae), bacillus licheniformis (Bacillus licheniormis), Rhodopseudomonas palustris (Rhodopseudomonas palustris) etc.
When described probiotic is the mixture of single bacterial strain preparation, according to employed bacterial strain and purposes, the thalline number of each bacterial strain can be selected certain ratio, for example described probiotic is the mixture of bacillus subtilis dry powder, brewer's yeast dry powder and bacillus licheniformis dry powder, can select bacillus subtilis: brewer's yeast: it is 10: 2～8: 1～5 that the thalline of bacillus licheniformis is counted ratio.
The weight proportion of described thalline dry powder and inserts is by the thalline content decision of thalline dry powder and final products.
The preparation method of prebiotics feed additive of the present invention is conventional method, in above-mentioned ratio probiotic and the sea-tangle powder, wheat bran and the zeolite powder that are pre-mixed evenly is mixed and made into prebiotics feed additive.
Described probiotic can use all probiotic formulations as feed addictive of selling on the market, also can adopt existing method preparation, for example the dry powder of probiotic can be cultivated by liquid fermentation equipment, with high speed centrifugation the thalline in the zymotic fluid is separated then, with hot blast or vacuum freeze drying mode bacterium mud drying is obtained, the viable bacteria concentration of the thalline dry powder of acquisition surpasses every gram 10,000,000,000.
In use, prebiotics feed additive and feed are fully mixed, add suitable water then, evenly stir, make probiotic evenly be bonded in the feed surface, improve the utilization rate of probiotic; Also can be used for preparing the pharmaceutical feed of non-antibiotic class such as vitamins nutrient drug etc., can increase the adhesive effect between medicine and feed, improve utilization ratio of drug.
Advantage of the present invention is:
(1) significantly improves the survival rate of thalline in airtight package;
(2) the brown alga colloidal substance by being rich in the sea-tangle powder forms one deck marine alga glued membrane on the feed surface, has increased the adhesive effect between additive and feed, and has improved the utilization rate of additive;
(3) nutritional labeling and multiple bioactivators such as the iodine by being rich in the sea-tangle powder, algal polysaccharides, sweet mellow wine improve the animal immune ability and obviously improve meat;
(4) utilize more than 20 kind of constant such as the calcium that contains in this aluminium silicate mineral of zeolite powder, phosphorus, potassium, sodium, magnesium, zinc, copper, manganese and trace element, improve the nutritive value of probio, promote the metabolism of animal, improve the resistance against diseases of body, promote growth of animal, finally improved economic benefit;
(5) utilize the good adsorption and the ion exchangeable of zeolite powder, inhale ammonia fixed nitrogen, delay nutriment by the gastral time, and absorption harmful intestinal tract material, digestive function improved.
The specific embodiment
Following experiment and operational instances are further to explanation of the present invention, should not be used as limitation of the present invention.
Embodiment 1:
Use the corresponding culture medium of optimizing, cultivate bacillus subtilis, brewer's yeast, bacillus licheniformis and Rhodopseudomonas palustris respectively separately by liquid fermentation equipment, with supercentrifuge the thalline in the zymotic fluid is separated then, with hot blast or vacuum freeze drying mode with centrifugal bacterium mud drying of coming out, obtaining viable bacteria content is the bacillus subtilis dry powder of 20,000,000,000/gram, viable bacteria content is the brewer's yeast dry powder of 20,000,000,000/gram, and viable bacteria content is that the bacillus licheniformis dry powder and the viable bacteria content of 15,000,000,000/gram is the Rhodopseudomonas palustris of 15,000,000,000/gram.
Embodiment 2:
Take by weighing bacillus subtilis dry powder 50.0g, brewer's yeast dry powder 25.0g and bacillus licheniformis dry powder 13.3g that embodiment 1 obtains, be mixed into thalline dry powder 88.3g.Take by weighing sea-tangle powder 759.7g in addition, wheat bran 76.0g, zeolite powder 76.0g are mixed into inserts 911.7g.Thalline dry powder and inserts are put into agitator together fully mix, pack, promptly get product 1 of the present invention.The bacillus subtilis viable bacteria content is that 1,000,000,000/gram, brewer's yeast viable bacteria content are that 500,000,000/gram and bacillus licheniformis viable bacteria content are 200,000,000/gram in this product, it is 10: 5: 2 that thalline is counted ratio, the mass ratio of sea-tangle powder, wheat bran, three kinds of inserts of zeolite powder is 10: 1: 1, and thalline dry powder and inserts mass ratio are 1: 10.3.
Embodiment 2:
Take by weighing bacillus subtilis dry powder 100.0g, brewer's yeast dry powder 20.0g and bacillus licheniformis dry powder 40.0g that embodiment 1 obtains, be mixed into thalline dry powder 160.0g.Take by weighing sea-tangle powder 646.2g in addition, wheat bran 129.2g, zeolite powder 64.6g are mixed into inserts 840.0g.Thalline dry powder and inserts are put into agitator together fully mix, pack, promptly get product 2 of the present invention.The bacillus subtilis viable bacteria content is that 2,000,000,000/gram, brewer's yeast viable bacteria content are that 400,000,000/gram and bacillus licheniformis viable bacteria content are 600,000,000/gram in this product, it is 10: 2: 3 that thalline is counted ratio, the mass ratio of sea-tangle powder, wheat bran, three kinds of inserts of zeolite powder is 10: 2: 1, and thalline dry powder and inserts mass ratio are 1: 5.3
Embodiment 3:
With product 1, product 2 and control group are stored down at 25 ℃, regularly take a sample then, check the survival rate of various thalline, the results are shown in Table 1.Control group all is the wheat bran except that inserts, and other condition is identical with embodiment 1.
Table 1 contains the prebiotics feed additive of sea-tangle powder and zeolite powder and does not contain the thalline survival rate contrast of the prebiotics feed additive of sea-tangle powder and zeolite powder
| Project | Sample time | ||||||||
| 3 months | 6 months | 12 months | |||||||
| Product 1 | Product 2 | Contrast | Product 1 | Product 2 | Contrast | Product 1 | Product 2 | Contrast | |
| Bacillus subtilis survival rate (%) | ????98 | ????96 | ????93 | ????96 | ????94 | ????85 | ????90 | ????89 | ????71 |
| Saccharomyces cerevisiae survival rate (%) | ????99 | ????97 | ????95 | ????98 | ????97 | ????83 | ????93 | ????91 | ????70 |
| Bacillus licheniformis survival rate (%) | ????98 | ????96 | ????90 | ????95 | ????94 | ????84 | ????89 | ????86 | ????67 |
The result shows, stores after 12 months down for 25 ℃, and the survival rate of three kinds of bacterium is higher than control group more than 18% in product 1, the product 2.This shows, add an amount of sea-tangle powder, zeolite powder after, can significantly improve bacillus subtilis, brewer's yeast and the bacillus licheniformis survival rate in airtight package.
Embodiment 4:
Take by weighing the Rhodopseudomonas palustris dry powder 77g that embodiment 1 obtains, take by weighing in addition and take by weighing sea-tangle powder 769g in addition, wheat bran 77g, zeolite powder 77g are mixed into inserts 923g.Thalline dry powder and inserts are put into agitator together fully mix, pack, promptly get product 3 of the present invention, thalline dry powder and inserts mass ratio are 1: 12 in this product.Control group inserts 923g is wheat bran entirely, and all the other conditions are identical.Through 12 months thalline survival rate products 3 was 86%, and contrast is 69%.
Embodiment 5:
Take by weighing the Rhodopseudomonas palustris dry powder 200g that embodiment 1 obtains, take by weighing in addition and take by weighing sea-tangle powder 535g in addition, wheat bran 159g, zeolite powder 106g are mixed into inserts 800g.Thalline dry powder and inserts are put into agitator together fully mix, pack, promptly get product 4 of the present invention, thalline dry powder and inserts mass ratio are 1: 4 in this product, and the mass ratio of sea-tangle powder, wheat bran, three kinds of inserts of zeolite powder is 10: 3: 2.Control group inserts 800g is wheat bran entirely, and all the other conditions are identical.Through 12 months thalline survival rate products 4 was 81%, and contrast is 69%.
Claims (3)
1. a prebiotics feed additive is characterized in that being made up of the probiotic and the inserts that by mass ratio are 1: 4～12, and described inserts is sea-tangle powder, wheat bran and the zeolite powder of mass ratio 10: 1～3: 1～2.
2. according to a kind of prebiotics feed additive of claim 1, it is characterized in that described probiotic is made up of bacillus subtilis (Bacillus subtilis) dry powder, brewer's yeast (Saccharomyces cerevisiae) dry powder and bacillus licheniformis (Bacillus licheniormis) dry powder.
3. according to a kind of prebiotics feed additive of claim 2, it is 10: 2～8: 1～5 that the thalline that it is characterized in that described bacillus subtilis, brewer's yeast and bacillus licheniformis is counted ratio.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100777064A CN1245095C (en) | 2004-12-30 | 2004-12-30 | Probiotic feed additive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100777064A CN1245095C (en) | 2004-12-30 | 2004-12-30 | Probiotic feed additive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1631205A true CN1631205A (en) | 2005-06-29 |
| CN1245095C CN1245095C (en) | 2006-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100777064A Expired - Fee Related CN1245095C (en) | 2004-12-30 | 2004-12-30 | Probiotic feed additive |
Country Status (1)
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| CN (1) | CN1245095C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731452A (en) * | 2010-03-23 | 2010-06-16 | 上海交通大学 | Manufacturing method of composite probiotic fermented feed |
| CN101779731A (en) * | 2010-03-12 | 2010-07-21 | 韶关市颐林泉生物科技有限公司 | Feed additive |
| CN1908155B (en) * | 2006-08-15 | 2011-05-04 | 浙江省农业科学院 | Microbial viable bacteria combination and preparation method thereof |
| CN102138639A (en) * | 2011-01-26 | 2011-08-03 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102334610A (en) * | 2011-09-05 | 2012-02-01 | 李文有 | Antibiotic-free environment-friendly biological feed and production method thereof |
| CN102894219A (en) * | 2012-09-26 | 2013-01-30 | 国家海洋局第三海洋研究所 | Reconstitutable microecological gel for sea cucumber and abalone culture and preparation method thereof |
| CN106490322A (en) * | 2016-10-25 | 2017-03-15 | 内蒙古凯程农牧业科技有限公司 | A kind of adhesive, pellet and preparation method thereof and system |
| CN107307224A (en) * | 2017-07-06 | 2017-11-03 | 合肥皖高特种家禽养殖科技有限公司 | A kind of probiotic formulations strengthen goose metabolism and immune feed |
-
2004
- 2004-12-30 CN CNB2004100777064A patent/CN1245095C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1908155B (en) * | 2006-08-15 | 2011-05-04 | 浙江省农业科学院 | Microbial viable bacteria combination and preparation method thereof |
| CN101779731A (en) * | 2010-03-12 | 2010-07-21 | 韶关市颐林泉生物科技有限公司 | Feed additive |
| CN101731452A (en) * | 2010-03-23 | 2010-06-16 | 上海交通大学 | Manufacturing method of composite probiotic fermented feed |
| CN101731452B (en) * | 2010-03-23 | 2012-09-05 | 上海交通大学 | Manufacturing method of composite probiotic fermented feed |
| CN102138639A (en) * | 2011-01-26 | 2011-08-03 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102138639B (en) * | 2011-01-26 | 2014-11-12 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102334610A (en) * | 2011-09-05 | 2012-02-01 | 李文有 | Antibiotic-free environment-friendly biological feed and production method thereof |
| CN102894219A (en) * | 2012-09-26 | 2013-01-30 | 国家海洋局第三海洋研究所 | Reconstitutable microecological gel for sea cucumber and abalone culture and preparation method thereof |
| CN106490322A (en) * | 2016-10-25 | 2017-03-15 | 内蒙古凯程农牧业科技有限公司 | A kind of adhesive, pellet and preparation method thereof and system |
| CN107307224A (en) * | 2017-07-06 | 2017-11-03 | 合肥皖高特种家禽养殖科技有限公司 | A kind of probiotic formulations strengthen goose metabolism and immune feed |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1245095C (en) | 2006-03-15 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Guangmufeng Biotechnology Co., Ltd., Guangzhou Assignor: Guangdong Entomological Institute Contract fulfillment period: 2008.10.8 to 2016.10.7 contract change Contract record no.: 2009440000771 Denomination of invention: Probiotic feed additive Granted publication date: 20060315 License type: Exclusive license Record date: 2009.7.22 |
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Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.10.8 TO 2016.10.7; CHANGE OF CONTRACT Name of requester: GUANGZHOU GUANGMUFENG BIOTECHNOLOGY CO., LTD. Effective date: 20090722 |
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| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060315 Termination date: 20101230 |