CN1615929A - Medicine for treating wind-dampness syndrome - Google Patents
Medicine for treating wind-dampness syndrome Download PDFInfo
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- CN1615929A CN1615929A CN 200310113423 CN200310113423A CN1615929A CN 1615929 A CN1615929 A CN 1615929A CN 200310113423 CN200310113423 CN 200310113423 CN 200310113423 A CN200310113423 A CN 200310113423A CN 1615929 A CN1615929 A CN 1615929A
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Abstract
The medicine for treating wind-wetness arthralgia is prepared with nine kinds of Chinese medicinal materials, including white mustard seed, prepared aconite, aucklandia root, cassia twig, atractylodes rhizome, etc. and through sorting material, stoving, curshing and mixing. It is applied externally and has high curative rte and no toxic side effect. I is used in treating rheumatism, rheumarthritis, rheumatoid arthritis, osteal arthritis, protrusion of lumbar intervertebral disc, etc.
Description
One, technical field
The present invention relates to a kind of medicine for the treatment of arthralgia due to wind-cold-dampness disease, be specifically related to external pulvis medicine with prepared from traditional Chinese medicines.
Two, background technology
Arthralgia due to wind-cold-dampness disease, cardinal symptom is: limbs, joint, myalgia, numbness, weighing, the joint joint stuffiness is met cold then pain, and then pain is slow to meet heat; Or limbs joint aches, and migration is indefinite, is regardless of up and down; Or the heavy swelling and pain of limbs joint, arthroncus is not weighing and is moving, the extremity inconvenient activity.Modern medicine classifies as above-mentioned symptom: rheumatism, rheumatic arthritis, rheumatoid arthritis, osteoarthritis, scapulohumeral periarthritis, cervical spondylosis, prolapse of lumbar intervertebral disc, sciatica, puerperal exposure to wind etc.
Above-mentioned disease adopts western medicines such as piroxicam, diclofenac, prednisone, is difficult to eradicate, and takes sx or disappearance behind the medicine, and after the drug withdrawal, symptom also can occur, and cure rate is low; On the other hand, it is big to take the Western medicine side effect, hinders intestinal, stomach, liver, kidney.At present, adopt the above-mentioned disease of treatment by Chinese herbs, though can overcome the big defective of Western medicine side effect, the decoction of Chinese medicine will be through fried, the medication trouble, oral process misery, the external application medicine that also useful Chinese medicine is made, though reduce fried, oral process, a plaster will paste more than ten day, very inconvenient, and curative effect is very little.
Three, summary of the invention
The objective of the invention is provides a kind of good effect, medication to treat the medicine of arthralgia due to wind-cold-dampness disease easily in order to overcome the deficiency of prior art.
The present invention is to cure 175 of holy Zhang Zhongjing treatise on Febrile Diseases " invasion of the body by blended pathogenic wind and dampness, acute pain in the joints; dragging pain must not bend and stretch; near then pain play, sweating, lose heart; dysuria; aversion to wind no desire to take off clothes; or slight swelling of the body person, the Radix Glycyrrhizae et Radix Aconiti Lateralis Preparata Decoction master it " be theoretical foundation, Radix Glycyrrhizae et Radix Aconiti Lateralis Preparata Decoction added simplify sanction, the Radix Aconiti Lateralis Preparata of Aconitum carmichjaelii Debx. daughter root is changed into the Radix Aconiti of Aconitum carmichjaelii Debx. parent root; the Rhizoma Atractylodis Macrocephalae changes Rhizoma Atractylodis into; add medicines such as the Radix Aucklandiae, Semen Sinapis, dosage form for oral administration is changed into the external application dosage form, with the principle of traditional Chinese medical science inner disease outer treat; the external application part, the treatment arthralgia due to wind-cold-dampness disease.
For achieving the above object, technical scheme of the present invention is: according to composition by weight, will: 10-15 part Semen Sinapis, 1.5-2 part Radix Aconiti Preparata, 1.5-2 part Radix Aconiti Kusnezoffii Preparata, 8--12 part Radix Aucklandiae, 6-9 part Ramulus Cinnamomi, 8--12 part Rhizoma Atractylodis, 0.8-1 part Styrax, 1--2 part Radix Glycyrrhizae, 3--5 part Olibanum, after selecting materials, dry, pulverizing, cross 40 mesh sieves, mixing, quantitative package.
The medicine optimum weight component of above-mentioned treatment arthralgia due to wind-cold-dampness disease is: 10 parts of Semen Sinapiss, 1.5 parts of Radix Aconiti Preparatas, 1.5 parts of Radix Aconiti Kusnezoffii Preparatas, 8 parts of Radix Aucklandiae, 6 parts of Ramulus Cinnamomi, 8 parts of Rhizoma Atractylodis, 0.5 part of Styrax, 1.5 portions of Radix Glycyrrhizaes, 3 parts of Olibanums, after selecting materials, dry, pulverizing, cross 40 mesh sieves, mixing, quantitative package.
The performance that relates to various medical herbs in the pharmaceutical formulation of the present invention:
Radix Aconiti Preparata suffering, hardship, heat, the Shennong's Herbal cloud: " wind and cold cough with dyspnea pathogen, Han Shi Wei lame, contracture pain, in the unable to walk step, broken disease heavily fortified point gathers arthralgia due to stagnation of blood, incised wound ".Compendium of Material Medica cloud: " controlling three cloudy typhoid fever, insidious colic of cold type, invasion by pathogenic cold apoplexy ... anemofrigid-damp arthralgia, generalized edema with distention of the chest and abdomen beriberi ".This product suffering can be dispeled the wind, bitter energy dampness, and dispelling cold by warming the meridian hot in nature, thus the energy expelling wind and removing dampness, dispersing cold for relieving pain.
Radix Aconiti Kusnezoffii Preparata suffering, hardship, heat, the Shennong's Herbal cloud: " the apoplexy aversion to wind washes out antiperspirant, eliminating cold-damp numbness, and cough with dyspnea ends gas, removing mass gathers cold and heat ".Compendium of Material Medica cloud: " main strong wind insensitive impediment ".This product expelling wind and removing dampness, antalgic is applicable to arthralgia due to wind-cold-dampness disease.
Ramulus Cinnamomi suffering, sweet, warm, Shennong's Herbal cloud: " sore throat is told suction, sharp joint for Your Majesty's gas cough with dyspnea, stagnation of QI "." pearl sac " cloud: " removing anemogenous headache, loosing the interspaces of skin and muscles, relieving the exterior syndrome by diaphoresis, peeling skin rheumatism "." herbal classic is dredged card " cloud: " the sharp joint of energy, warming the meridian and promoting blood circulation ".
Rhizoma Atractylodis suffering, hardship, temperature, Shennong's Herbal cloud: " main air cold-damp numbness, dead flesh convulsion subcutaneous ulcer "." property of medicine opinion " cloud: " the edema distension removes cold and heat, ends under the singultus and lets out cold-dysentery for main big migratory arthralgia, trusted subordinate's distending pain ".This product fragrant odour hot looses bitter dryly, is longer than damp eliminating, is suitable for the arthromyodynia victor that wets especially.
Radix Aucklandiae suffering, hardship, temperature, Compendium of Material Medica cloud: " Radix Aucklandiae is three warmers, the medicine of edema caused by disorder of QI, all gas of energy lifting ".This product fragrance, hot row, hardship are let out promoting the circulation of QI to relieve pain.
Semen Sinapis, Xin Wen, the Compendium of Material Medica cloud: " the promoting the circulation of QI eliminating phlegm removes in cold the warming up, and reducing swelling and alleviating pain is controlled and breathed heavily the regurgitation of coughing, numbness wood beriberi, the muscles and bones waist saves all pains ".This product fragrance is wandered away, the promoting the circulation of QI machine, and the meridian dredging is changed cold-phlegm, and by pathogenic fluid-retention, kind control " expectorant that the flesh side film is outer " again can dispersing swelling and dissipating binds, removing obstruction in the collateral to relieve pain.
Styrax, Xin Wen.Compendium of Material Medica cloud: " gas perfume (or spice) is scurried, and can lead to all key internal organs, so its function is warded off all not just gas ".The hot fragrance of this product is strong, and temperature leads to walk to scurry, and the refreshment of can having one's ideas straightened out is warded off dirty, can change turbid dissipating depression of QI again, the cold relieving pain relieving.
Olibanum suffering, hardship, temperature, the Compendium of Material Medica cloud: " both all poison of eliminating carbuncle cellulitis, the heart is protected in the Tuoli, and muscle is stretched in the analgesic therapy of invigorating blood circulation, and controls married woman's difficult labour, folding is hindered ".This product fragrance, the hot temperature of loosing is logical, can the blood-activating and qi-promoting pain relieving, again can blood stasis dispelling stretch muscle and exempt from numbness, the dispelling the wind and dampness pathogens arthralgia pain.
Radix Glycyrrhizae, sweet flat, " book on Chinese herbal medicine is just " cloud: " property that must neutralize has the merit of transferring benefits, thus poison get separate its poison, firm medicine gets its property of sum, what medicine administered to bring out the cold got helps outside it, put in poison delay its speed.It is strong and alleviate toxic and side effects that this product can relax its medicine.
Radix Aconiti, Radix Aconiti Kusnezoffii and usefulness in the side, expelling wind and removing dampness, dispelling cold by warming the meridian is treated arthromyodynia originally, so monarch drug in the side of being; The auxiliary monarch drug of Ramulus Cinnamomi, Rhizoma Atractylodis, Semen Sinapis strengthens expelling wind and removing dampness, the dispelling cold by warming the meridian function, so and be ministerial drug; The Radix Aucklandiae, Olibanum, the circulation of qi promoting of Styrax fragrance are transported to help blood, promptly so-called " gas very then blood is lived, and the stagnation of QI is blood stasis then, the Olibanum blood circulation promoting and blood stasis dispelling, and QI and blood is logical transfers, and arthralgia pain ends certainly, i.e. so-called " stagnation of QI and blood may bring about pain, general rule are not bitterly ", " control wind and control blood earlier, the blood sector-style is from going out ".Three medicines share promoting flow of QI and blood, and auxiliary the monarch and his subjects' product are to reach the merit of exempting from the numbness pain relieving, so be adjuvant drug altogether; Radix Glycyrrhizae is sweet slow, and it is strong and alleviate toxic and side effects to relax its medicine, coordinating the actions of various ingredients in a prescription effect and be messenger drug.
Take a broad view of we, occupy the minister assistant and make compatibility orderly, prescription is sent medicine two big characteristics.One, giving consideration to both the incidental and fundamental, the monarch and his subjects' five medicine expelling wind and removing dampness in the side, dispelling cold by warming the meridian, with the basis of the arthromyodynia wind-cold damp pathogen cause of disease of dispelling, three kinds of adjuvant drug promoting flow of QI and blood, to end the mark of arthromyodynia pain, specimen is also controlled, and brings out the best in each other; Its two, the warm fragrance of medication hot looses bitter dryly, used nine medicines all belong to the warm gas eight flavor medicines of producing and are hot diffusing flavor, five kinds of property that medical instrument is bitter dry, the product of five kinds of Chinese medicine system fragrance cover warm cold expelling, and wind fortunately can loose, bitter domination of dryness is wet, the fragrance row, and promoting blood circulation and stopping pain is exempted from anemofrigid-damp arthralgia altogether.
Using method: medicine of the present invention is a kind of medicine for external use, with 15-40 ℃ warm water with this drug powder (medicated powder) furnishing pasty state, be poured on the plastic foil, spread the back out and keep 4-8 millimeter thickness, stick, cover or encase with cotton soft object in the affected part, the thickness and the temperature that keep mass, remove about 50 minutes, the drug of topical application for the second time is 8 day time at interval, and the drug of topical application once is a course of treatment.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the present invention's natural plant is a raw material, and human body is had no side effect, and need not decoct, take orally.
Though 2, the present invention local application, the efficacy of a drug is walked whole body, and the cure rate height.
3, drug of topical application time weak point of the present invention, a drug of topical application only needs about 50 minutes, and twice medication interval is long, and the time is 8 days, has reduced the trouble that frequent medication brings.
In order to prove that medicine of the present invention has the effect of treatment arthralgia due to wind-cold-dampness disease brilliance, the present invention has done a large amount of clinical observations, now clinical experiment is disclosed as follows:
Select case
1, alternative is rheumatism, rheumatic arthritis, rheumatoid arthritis, osteoarthritis, scapulohumeral periarthritis, cervical spondylosis, prolapse of lumbar intervertebral disc, sciatica, puerperal exposure to wind patient.
2, age 28-68 year, male or female, contraindication in pregnancy.
The case diagnosis standard
The traditional Chinese medical science is debated knowledge and is formulated by national unified editing traditional Chinese medical science universities and colleges teaching material;
Doctor trained in Western medicine is formulated by national unified editing doctor trained in Western medicine universities and colleges teaching material.
Therapeutic scheme
1, case grouping: select case 1760 examples, 880 examples are organized in treatment, matched group 880 examples.Wherein:
Rheumatism 460 examples that state of an illness sign is roughly the same, 230 examples are organized in treatment, matched group 230 examples;
Rheumatic arthritis 360 examples that state of an illness sign is roughly the same, 180 examples are organized in treatment, matched group 180 examples;
Rheumatoid arthritis 220 examples that state of an illness sign is roughly the same, 110 examples are organized in treatment, matched group 110 examples;
Osteoarthritis 40 examples that state of an illness sign is roughly the same, 20 examples are organized in treatment, matched group 20 examples;
Scapulohumeral periarthritis 220 examples that state of an illness sign is roughly the same, 110 examples are organized in treatment, matched group 110 examples;
Cervical spondylosis 80 examples that state of an illness sign is roughly the same, 40 examples are organized in treatment, matched group 40 examples;
Prolapse of lumbar intervertebral disc 120 examples that state of an illness sign is roughly the same, 60 examples are organized in treatment, matched group 60 examples;
Sciatica 220 examples that state of an illness sign is roughly the same, 110 examples are organized in treatment, matched group 110 examples;
The puerperal exposure to wind that state of an illness sign is roughly the same, treatment are organized 20 examples, matched group 20 examples;
Medicine is formed:
10 parts of Semen Sinapiss, 1.5 parts of Radix Aconiti Preparatas, 1.5 parts of Radix Aconiti Kusnezoffii Preparatas, 8 parts of Radix Aucklandiae, 6 parts of Ramulus Cinnamomi, 8 parts of Rhizoma Atractylodis, 0.5 part of Styrax, 1.5 portions of Radix Glycyrrhizaes, 3 parts of Olibanums after selecting materials, dry, pulverizing, are crossed 40 mesh sieves, mixing, quantitative package.
Using method:
The treatment group: with 40 ℃ warm water with this drug powder (medicated powder) furnishing pasty state, be poured on the plastic foil, spread the back out and keep 4-8 millimeter thickness, stick in the affected part, cover or encase with the soft object of cotton, keep the thickness and the temperature of mass, remove about 50 minutes, the drug of topical application for the second time is 8 day time at interval, and the drug of topical application once is a course of treatment.
Matched group: conventional western medicine.
Efficacy evaluation
Efficacy assessment standard
1, recovery from illness: after finishing the course of treatment, symptom, sign disappear, and the laboratory leading indicator is recovered or be approaching normal.
2, produce effects: after finishing the course of treatment, symptom, sign disappear substantially, and the laboratory leading indicator also has clear improvement.
3, effective: after finishing the course of treatment, symptom, sign alleviate, and the laboratory leading indicator also has improvement.
4, invalid: after finishing the course of treatment, symptom, sign and other index do not have obvious improvement.
The efficacy evaluation result
There were significant differences for the two groups of total effectses in treatment back, treatment group total effective rate 95%, and cure-remarkable-effectiveness rate 82%, treatment group clinical effectiveness is apparently higher than matched group.
| Treatment group and matched group are always treated statistical table (course of treatment) | |||||||
| The example number | Recovery from illness | Produce effects | Effectively | Invalid | Cure-remarkable-effectiveness rate % | Total effective rate % | |
| The treatment group | 880 | ?633 | ?90 | ?113 | ?44 | ????82 | ????95 |
| Matched group | 880 | ?370 | ?210 | ?120 | ?110 | ????66 | ????87 |
Four, the specific embodiment
According to composition by weight, will: 12 parts of Semen Sinapiss, 1.5 parts of Radix Aconiti Preparatas, 1.5 parts of Radix Aconiti Kusnezoffii Preparatas, 10 parts of Radix Aucklandiae, 6 parts of Ramulus Cinnamomi, 9 parts of Rhizoma Atractylodis, 1 part of Styrax, 11 portions of Radix Glycyrrhizaes, 3 parts of Olibanums, after selecting materials, dry, pulverizing, cross 40 mesh sieves, mixing, quantitative package.
When treatment is used, with 40 ℃ warm water with this drug powder (medicated powder) furnishing pasty state, be poured on the plastic foil, spread the back out and keep 4-8 millimeter thickness, stick, cover or encase with cotton soft object in the affected part, the thickness and the temperature that keep mass, remove about 50 minutes, the drug of topical application for the second time is 8 day time at interval, and the drug of topical application once is a course of treatment.
Claims (2)
1, a kind of medicine for the treatment of arthralgia due to wind-cold-dampness disease, it is characterized in that according to composition by weight, will: 10--15 part Semen Sinapis, 1.5--2 part Radix Aconiti Preparata, 1.5--2 part Radix Aconiti Kusnezoffii Preparata, 8--12 part Radix Aucklandiae, 6--9 part Ramulus Cinnamomi, 8--12 part Rhizoma Atractylodis, 0.8--1 part Styrax, 1--2 part Radix Glycyrrhizae, 3--5 part Olibanum, after selecting materials, dry, pulverizing, cross 40 mesh sieves, mixing, quantitative package.
2, the medicine of treatment arthralgia due to wind-cold-dampness disease as claimed in claim 1, it is characterized in that according to heavy component, with 10 parts of Semen Sinapiss, 1.5 parts of Radix Aconiti Preparatas, 1.5 parts of Radix Aconiti Kusnezoffii Preparatas, 8 parts of Radix Aucklandiae, 6 parts of Ramulus Cinnamomi, 8 parts of Rhizoma Atractylodis, 0.5 part of Styrax, 1.5 portions of Radix Glycyrrhizaes, 3 parts of Olibanums, after selecting materials, dry, pulverizing, cross 40 mesh sieves, mixing, quantitative package.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310113423 CN1278706C (en) | 2003-11-10 | 2003-11-10 | Medicine for treating wind-dampness syndrome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310113423 CN1278706C (en) | 2003-11-10 | 2003-11-10 | Medicine for treating wind-dampness syndrome |
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| Publication Number | Publication Date |
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| CN1615929A true CN1615929A (en) | 2005-05-18 |
| CN1278706C CN1278706C (en) | 2006-10-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200310113423 Expired - Lifetime CN1278706C (en) | 2003-11-10 | 2003-11-10 | Medicine for treating wind-dampness syndrome |
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| Country | Link |
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| CN (1) | CN1278706C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526238A (en) * | 2012-02-09 | 2012-07-04 | 中国中医科学院中药研究所 | Chinese medicinal composition for preventing and treating rheumatoid arthritis |
| CN104524482A (en) * | 2015-02-02 | 2015-04-22 | 范晓华 | Traditional Chinese medicine composition for treating scapulohumeral periarthritis and preparation method of traditional Chinese medicine composition |
| CN107595951A (en) * | 2017-11-02 | 2018-01-19 | 王静芳 | The cold moxibustion of dispellieg cold and dampness pain dissipates |
| CN110051816A (en) * | 2019-04-25 | 2019-07-26 | 孙安民 | A kind of Chinese medicine composition of warming and activating meridian |
-
2003
- 2003-11-10 CN CN 200310113423 patent/CN1278706C/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526238A (en) * | 2012-02-09 | 2012-07-04 | 中国中医科学院中药研究所 | Chinese medicinal composition for preventing and treating rheumatoid arthritis |
| CN104524482A (en) * | 2015-02-02 | 2015-04-22 | 范晓华 | Traditional Chinese medicine composition for treating scapulohumeral periarthritis and preparation method of traditional Chinese medicine composition |
| CN107595951A (en) * | 2017-11-02 | 2018-01-19 | 王静芳 | The cold moxibustion of dispellieg cold and dampness pain dissipates |
| CN110051816A (en) * | 2019-04-25 | 2019-07-26 | 孙安民 | A kind of Chinese medicine composition of warming and activating meridian |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1278706C (en) | 2006-10-11 |
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Effective date of registration: 20120904 Address after: 830000 Baoshan rheumatology Hospital of traditional Chinese medicine, Baoshan Road, Urumqi, the Xinjiang Uygur Autonomous Region 4, China Patentee after: XINJIANG JINSHIKANG PHARMACEUTICAL Co.,Ltd. Address before: 830000, the Xinjiang Uygur Autonomous Region Manasi County Housing Project No. three, building on the third floor of the left Patentee before: Wang Jinyang |
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