CN1404850A - Anti-inflammatory pain-releaving and swelling-diminishing external-use medicine - Google Patents

Abstract

The Chinese medicine for external application for relieving inflammation, subduing swelling and stopping pain, mainly for curing anasarca or local edema due to tumor and carcinomatosis with high effective rate of above 96% is made up by using 20 Chinese medicinal materials of puccoon. Sichuan fritillaria bulb, nux vomica, carthamus, cyathula root, corydalis tuber and others as raw material. Besides, it also can be used for curing the diseases of rheumatism, traumatic injury, scapulohumeral periarthritis, arthritis, lumbago, thoracico-abdominal pain and others and various pains. It is low in cost, and has no toxic side effect.

Description

Anti-inflammatory pain-releaving and swelling-diminishing external-use medicine

The present invention relates to a kind of medicine for external use, the Chinese medicine formula of the antiinflammatory of especially a kind of energy, pain relieving, detumescent.

Because of whole body or the local edema that tumor, diabetes and other disease cause, be a kind of comparatively common multiple disease, its not only overslaugh patient's daily life and work, study, but also cause very big misery to the patient.Mostly there is the cost height in existing this class detumescence medicine, uses inconveniently, and shortcomings such as weak curative effect do not satisfy the demand of most of patients.In addition in daily life, arthritis, bruise, traumatic injury, breast stomachache, gastroenteralgia, weakness pain, pancreatitis, scapulohumeral periarthritis etc., be in, common complaint among the elderly, its sickness rate is higher, the face that relates to is wider.These are common, the medicine of frequently-occurring disease and treat, and its curative effect is still not obvious, and more or less also have toxic and side effects, therefore, are necessary to provide a kind of medicine for external use that can treat above-mentioned disease.

The object of the present invention is to provide a kind of can antiinflammatory, detumescence, again can removing obstruction in the collateral to relieve pain, the compound Chinese herb external preparation of blood circulation promoting.

Pharmaceutical preparation of the present invention is made by the raw material of following weight portion:

Radix Arnebiae (Radix Lithospermi) 10-16 part Bulbus Fritillariae Cirrhosae 10-16 part Semen Strychni 1-2 part

Flos Carthami 10-11 part Radix Cyathulae 15-18 part Rhizoma Corydalis 10-12 part

Sanguis Draxonis 1-1.5 part Caulis Clematidis Armandii 20-25 share tea 3.5-6 part

Radix Aconiti 2-3 part Pseudobulbus Cremastrae Seu Pleiones 10-15 part Rhizoma Pinelliae 10-16 part

Radix Aconiti Kusnezoffii 2-3 part Taraxacum 20-25 part Radix Angelicae Sinensis 10-16 part

Lignum Sappan 12-18 part Rhizoma Arisaematis 10-15 part Caulis Mahoniae 16-20 part

Fructus Piperis Longi 4-7 part Caulis Spatholobi 16-25 part.

The present invention adopts preparation method of the prior art, and the said medicine component is made various dosage forms easy to use, smears or spray or stick on the affected part to get final product.

Radix Arnebiae (Radix Lithospermi) in the described component (Radix Arnebiae), its nature and flavor are sweet, salty, cold, and GUIXIN, Liver Channel have removing heat from blood, an effect of the rash of invigorating blood circulation, detoxify; Nature and flavor suffering, the temperature of Flos Carthami (Flos Carthami), GUIXIN, Liver Channel can be controlled blood and stimulate the menstrual flow eliminating stasis to stop pain; Sanguis Draxonis (Demonorops Dracd) property sweet-salty, flat is gone into the heart, Liver Channel, has the dissipating blood stasis analgesic therapy, the effect of hemostasia and promoting granulation; Radix Aconiti (RadixAconiti) nature and flavor suffering, hardship, heat, very toxic are gone into the heart, liver,kidney,spleen warp, the expectorant of dispeling the wind, antalgic; Radix Aconiti Kusnezoffii (Radix AconitiKusnezoffii) nature and flavor suffering, hardship, heat, very toxic are gone into the heart, liver,kidney,spleen warp, dispel the wind and remove temperature, the effect of antalgic; Bulbus Fritillariae Cirrhosae (Bulbus Fritillariae Cirrhosae) nature and flavor hardship, sweet, be slightly cold, return lung, heart channel, can clearing heat and moistening lung, preventing phlegm from forming and stopping coughing; Sweet, the little hardship of Radix Cyathulae (Radix Cyathulae) property, flat is gone into the Liver and kidney warp, has eliminating blood stasis and inducing menstruation, logical joint, the effect of inducing diuresis for treating stranguria syndrome; Caulis Clematidis Armandii (C aulisClematidis Armandii) property is light, bitter, cold, goes into the heart, lung, small intestinal, urinary bladder channel, the energy clearing away heat and promoting diuresis, and the stimulating milk secretion of stimulating the menstrual flow cures mainly edema, gonorrhea, urinary obstruction; Lignum Sappan (Lignum Sappan) nature and flavor are sweet, salty, flat, and GUIXIN, liver, spleen channel cure mainly the promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain; Fructus Piperis Longi (Fructus Piperis Longi) nature and flavor suffering, heat are gone into stomach, large intestine channel, the energy warming spleen and stomach for dispelling cold, and the pain relieving of going down is used for coldness and pain in the epigastrium, vomits, has loose bowels; Liver, spleen channel are gone in Pseudobulbus Cremastrae Seu Pleiones (Pseudobulbus Cremastrae Seu Pleiones) sweet, the little suffering of nature and flavor, cold, energy heat-clearing and toxic substances removing, dissipating phlegm and resolving masses; Taraxacum (Heriba Taraxaci) nature and flavor hardship, sweet cold is returned liver, stomach warp, cures mainly heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; The nature and flavor of Radix Angelicae Sinensis are sweet, hot, warm, go into liver, the heart, spleen channel, can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; The nature and flavor suffering of the Rhizoma Pinelliae, temperature, poisonous, return spleen, stomach, lung meridian, cure mainly drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Rhizoma Arisaematis (Rhizoma Arisaematis) nature and flavor hardship, suffering, temperature, poisonous, go into lung, liver, spleen channel, energy drying dampness to eliminate phlegm, wind-expelling pain-stopping, mass dissipating and swelling eliminating; Caulis Spatholobi (Caulis Spatholobi) property hardship, sweet, warm is returned liver, kidney channel, can enrich blood, invigorates blood circulation, collateral dredging; Caulis Mahoniae (Caulis Mahoniae) nature and flavor hardship, cold is returned liver, stomach, large intestine channel, cures mainly heat clearing and damp drying, eliminating fire and detoxication; Catechu (Catechu) nature and flavor hardship, puckery, be slightly cold, go into lung meridian, can removing dampness granulation promoting, hold back skin ulcer; Semen Strychni (Semen Stry chni) nature and flavor hardship, cold, very toxic is gone into liver, spleen channel, has removing obstruction in the collateral to relieve pain, effects such as mass dissipating and swelling eliminating; Nature and flavor suffering, hardship, the temperature of Rhizoma Corydalis (Rhixoma Corydalis) are gone into liver, spleen channel, can invigorate blood circulation, and promoting the circulation of QI, pain relieving is used for the treatment of the breast side of body, epigastric pain.

The present invention has following advantage and effect: medication has stronger blood circulation promoting and blood stasis dispelling outside the present invention because the mutual compatibility of above-mentioned each component makes, removing obstruction in the collateral to relieve pain, effects such as antiinflammatory detumescent, can improve high blood coagulation state, dredging the meridian, rapid reduction of patient slight illness, to the inner disease outer treat of human body,, more show unique curative effect of this medicine for external use especially to the patient with advanced cancer of the difficulty of taking medicine, it can eliminate patient's edema in a short time, its effective percentage reaches more than 96%, so it is that a kind of cost is low, and is easy to use, have no side effect antiinflammatory releaving and swelling-diminishing external-use medicine evident in efficacy.It also can be used for treating swelling and ache that tumor, rheumatism, traumatic injury, scapulohumeral periarthritis, arthritis, lumbago and backache, breast stomachache, bruise, chronic appendicitis, cyclomastopathy, gastrointestinal tract pain, weakness pain, gallbladder renal colic and a variety of causes cause.

In clinical treatment, according to the not painful Therapeutic Principle of QI and blood regulating, blood circulation promoting and blood stasis dispelling, dredging the meridian, general rule, to carrying out following treatment because of gas, blood, disorderly various diseases and the complication that causes of body fluid operation:

1, because of the anasarca that tumor causes, be, thereby cause the human qi and blood running seriously disorderly because the paraplasm of cancerous cell has been occupied the human normal tissue organ.Its clinical symptoms mainly shows as:

A, pain; B, interstitial fluid ooze out the edema that causes; C, spirit depressing are depressed; D, feed are lacked.

In the patient of treatment, select tangible various tumor patient 165 examples of edema to carry out clinical observation, patient's 9 examples in 16-20 year wherein, patient's 11 examples in 20-30 year, patient's 18 examples in 30-40 year, patient's 26 examples in 40-50 year, patient's 24 examples in 50-60 year, patient's 73 examples in 60-70 year, patient's 4 examples more than 70 years old.The edema that is caused by pulmonary carcinoma among the patient has 86 examples, edema 63 examples that hepatocarcinoma causes, rectal cancer 8 examples, breast carcinoma 2 examples, cancer of pancreas 6 examples.

According to patient and relatives' thereof the oral account or the CT and the check pathological section result of hospital, in conjunction with the edema situation at swelling position, medicine was imposed on the affected part 24 hours, the next day, use once, eliminates up to edema.

Therapeutic effect is as follows: remove edema 1 exception that edema 2 examples that hepatocarcinoma causes and cancer of pancreas cause, all the other patients successively at 5-15 days internal diabetes except edema, spirit takes a turn for the better.Invalid 3 examples account for 1.8%, and total effective rate is 98.2%.

2, the edema that various traumatic injury cause is because muscle, tendon injury, makes its surrounding tissue ooze out blood or liquid and livid purple, the red and swollen phenomenon that takes place.Clinical manifestation is: pain, and swelling, scorching hot, functional activity obstacle etc.

From the patient of treatment, select frank 376 examples and observe, young patient 113 examples wherein, middle-older patient 163 examples, gerontal patient's 100 examples.According to the difference at new wound, old wound and position, new wound is 312 examples in 376 examples, and the old persistent ailment of hindering is 64 examples.

Using method is that medicine was imposed on the affected part 24 hours, and the next day uses once, eliminates up to edema.After the medication 24 hours, pain obviously alleviates, and the functional activity degree increases, and after 24 hours, the part still has ecchymosis again, but swelling obviously disappears, and pain disappears, and activity freely.

In the treatment only 5 people swelling after January just disappear, all the other patients all cured in 20 days, total effective rate 96%.

3, the unknown cause pain at positions such as waist, lower limb, breast abdomen, the breast side of body, normally not smooth because of the operation of gas, blood, the stasis of blood stagnates and blocks, and causes local nerve tip pressure to increase and causes.The clinical manifestation symptom is: local pain, feelings will are not relaxed, and be fidgety.

Select comparatively tangible 678 examples of symptom to carry out clinical observation from the patient of treatment, in the treatment medicine was imposed on sore place or each main acupuncture point, meridians place 24 hours, the next day, use once, eliminates up to pain.

After the medication in 24 hours alleviation person's 640 examples, not obvious person's 28 examples of pain relief, nonresponder's 10 examples, total effective rate 98%.

4, gastrointestinal tract pain, normally because unhygienic diet, eating cold and uncooked food excessively food has reason such as gastroenteropathy to cause.Its clinical manifestation is: Upper abdominal pain, and stool abnormity, or do not have just or have loose bowels.

Clinical treatment 394 examples in therapeutic process, are point of care with the umbilicus, promptly paste medicine at umbilicus, wherein cure 300 examples, obvious alleviator's 34 examples of symptom, and symptom is alleviator's 12 examples to some extent, nonresponder's 48 examples, total effective rate 87.8%.

Embodiment 1

Take by weighing raw material (kilogram) by following proportioning, and adopt existing processing technique to make just ointment to use:

1 part of 10 parts of Semen Strychni of 10 parts of Bulbus Fritillariae Cirrhosaes of Radix Arnebiae (Radix Lithospermi)

10 parts of 15 parts of Rhizoma Corydalis of 10 portions of Radix Cyathulaes of Flos Carthami

3.5 parts of 1 portion of Caulis Clematidis Armandii of Sanguis Draxonis, 20 share tea

10 parts of 10 parts of Rhizoma Pinelliaes of 2 parts of Pseudobulbus Cremastrae Seu Pleioness of Radix Aconiti

10 parts of 20 parts of Radix Angelicae Sinensis of 2 parts of Taraxacums of Radix Aconiti Kusnezoffii

16 parts of 10 parts of Caulis Mahoniaes of 12 parts of Rhizoma Arisaematiss of Lignum Sappan

16 parts of 4 portions of Caulis Spatholobis of Fructus Piperis Longi.

Embodiment 2

Take by weighing raw material (kilogram) by following proportioning, have prior art to make masking liquid:

2 parts of 16 parts of Semen Strychni of 16 parts of Bulbus Fritillariae Cirrhosaes of Radix Arnebiae (Radix Lithospermi)

12 parts of 18 parts of Rhizoma Corydalis of 11 portions of Radix Cyathulaes of Flos Carthami

6 parts of 1.5 portions of Caulis Clematidis Armandiis of Sanguis Draxonis, 25 share tea

16 parts of 15 parts of Rhizoma Pinelliaes of 3 parts of Pseudobulbus Cremastrae Seu Pleioness of Radix Aconiti

16 parts of 25 parts of Radix Angelicae Sinensis of 3 parts of Taraxacums of Radix Aconiti Kusnezoffii

20 parts of 15 parts of Caulis Mahoniaes of 18 parts of Rhizoma Arisaematiss of Lignum Sappan

25 parts of 7 portions of Caulis Spatholobis of Fructus Piperis Longi.

Embodiment 3

Take by weighing raw material (kilogram) by following proportioning, make medicine for external use with existing technology:

2 parts of 14 parts of Semen Strychni of 13 parts of Bulbus Fritillariae Cirrhosaes of Radix Arnebiae (Radix Lithospermi)

11 parts of 16 parts of Rhizoma Corydalis of 10 portions of Radix Cyathulaes of Flos Carthami

4 parts of 1.2 portions of Caulis Clematidis Armandiis of Sanguis Draxonis, 23 share tea

13 parts of 12 parts of Rhizoma Pinelliaes of 2.5 parts of Pseudobulbus Cremastrae Seu Pleioness of Radix Aconiti

12 parts of 23 parts of Radix Angelicae Sinensis of 2.5 parts of Taraxacums of Radix Aconiti Kusnezoffii

18 parts of 12 parts of Caulis Mahoniaes of 15 parts of Rhizoma Arisaematiss of Lignum Sappan

20 parts of 5 portions of Caulis Spatholobis of Fructus Piperis Longi.

Claims (2)

1, a kind of antiinflammatory detumescent pain-stopping external use medicine is characterized in that it is the medicament of being made by the raw material of following weight portion:

Radix Arnebiae (Radix Lithospermi) 10-16 part Bulbus Fritillariae Cirrhosae 10-16 part Semen Strychni 1-2 part

Flos Carthami 10-11 part Radix Cyathulae 15-18 part Rhizoma Corydalis 10-12 part

Sanguis Draxonis 1-1.5 part Caulis Clematidis Armandii 20-25 share tea 3.5-6 part

Radix Aconiti 2-3 part Pseudobulbus Cremastrae Seu Pleiones 10-15 part Rhizoma Pinelliae 10-16 part

Radix Aconiti Kusnezoffii 2-3 part Taraxacum 20-25 part Radix Angelicae Sinensis 10-16 part

Lignum Sappan 12-18 part Rhizoma Arisaematis 10-15 part Caulis Mahoniae 16-20 part

Fructus Piperis Longi 4-7 part Caulis Spatholobi 16-25 part.

2,, it is characterized in that described medicament is the above a external-use drug form of any pharmaceutics according to the medicine for external use of stating of claim 1.