CN101062198A - Decoction for treating arthritis - Google Patents

Abstract

The invention discloses a medicinal decoction for treating rheumatism and chronic infectious arthritis, which is prepared from large-leaf gentian root 15g, notopterygium root 15g, pubescent angelica root 15g, ledebouriella root 15g, asarum herb 6g, prepared Sichuan aconite root 15g, prepared wild aconite root 15g, Tripterygium wilfordii 10g, orienavine 30g, Loranthus mulberry mistletoe 30g, processed semen strychni 3g, buthus martensi kirsch 6-10g, earthworm 10-15g and licorice root 5-10g.

Description

Decoction for treating arthritis

Technical field

The application belongs to Chinese medicine decoction, in particular for the Chinese medicine decoction of treatment rheumatism, rheumatoid arthritis.

Background technology

Rheumatism is a kind of common clinical, frequently-occurring disease, the tradition traditional Chinese medical science is referred to as " numbness disease ", be because exopathogen invasion and attack human body impatency meridians such as wind, cold, wet, heat, due to QI-blood circulation is smooth, with the muscle BJM ache, numb, bend the mainly existing disease of skin such as the unfavorable or arthroncus of body.At present the traditional Chinese medical science mainly based on dispel the wind, dehumidifying, cold expelling, QI invigorating, the treatment of enriching blood.

Summary of the invention

The application satisfies rheumatisant's demand, and a kind of decoction for the treatment of rheumatic arthritis is provided, and is referred to as decoction for treating arthritis.

One pair of decoction of the present invention mainly is made according to the Chinese medicine boiling method by the Chinese medicine ingredients of following weight:

Radix Gentianae Macrophyllae 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Daphne giraldii Nitsche 15g, Radix Saposhnikoviae 15g, Herba Asari 6g, Radix Aconiti Preparata 15g, Radix Aconiti Kusnezoffii Preparata 15g, Radix Tripterygii Wilfordii 10g, Caulis Sinomenii 30g, Herba Taxilli 30g, Semen Strychni (processed) 3g, Scorpio 6-10g, Pheretima 10-15g, Radix Glycyrrhizae 5-10g.

Below in conjunction with all medicine mechanism of action good effect of the present invention is described.

Radix Gentianae Macrophyllae: wind-damp dispelling, clearing away damp-heat are arranged, the merit of stopping numbness pain.Be used for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached.Physical and chemical composition mainly is the gentianin element, has better antipyretic, analgesia, antiinflammatory action.

Rhizoma Et Radix Notopterygii: expelling wind and removing dampness is arranged, the merit of numbness relieving and pain relieving.Be used for anemofrigid-damp arthralgia, lumbocrural pain, Rhizoma Et Radix Notopterygii volatile oil have antiinflammatory, analgesic, analgesic activity.

Radix Angelicae Pubescentis: expelling wind and removing dampness is arranged, the merit of numbness relieving and pain relieving.Be used for anemofrigid-damp arthralgia, the joint osteodynia.The physics and chemistry composition has sylvestrene, and 23 kinds of volatile oil such as australene is rare, octane have good analgesia, antiinflammatory action.

Refreshing teacher fiber crops: expelling wind and removing dampness is arranged, the merit of pain relieving dissipating blood stasis.Be used for rheumatic arthralgia, numb limbs and tense tendons, effectively physical and chemical composition is refreshing teacher fiber crops first element, has antiinflammatory, the painful effect in town.

Radix Saposhnikoviae: inducing diaphoresis to dispel wind is arranged, win and wet, the merit of relieving convulsion.Be used for rheumatic arthralgia, contain octanal in the Radix Saposhnikoviae volatile oil, β-heerabolene etc. have antiinflammatory, analgesia, anti-allergic effects.

Herba Asari: expelling wind and cold is arranged, understand things pain-stopping, the merit of warming the lung to resolve fluid-retention.Be used for rheumatic arthralgia, phlegm retention is breathed with cough.Volatile oil has antiinflammatory, analgesic, analgesic activity.

Radix Aconiti Preparata: expelling wind and removing dampness is arranged, the merit of antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, main physics and chemistry active ingredient aconitine has analgesia, and antiinflammatory suppresses immunization.

Radix Aconiti Kusnezoffii Preparata: expelling wind and removing dampness is arranged, the merit of antalgic.Be used for wind and cold temperature numbness, the joint pain.Physics and chemistry composition and act on same Radix Aconiti.

Radix Tripterygii Wilfordii: heat-clearing and toxic substances removing, expelling wind and removing dampness, dredge the meridian passage, reducing swelling and alleviating pain.Be used for rheumatoid arthritis, mainly containing effective constituent is wilfordine, wilfordine etc., has antiinflammatory action, and stronger inhibition immunization is arranged.

Caulis Sinomenii: wind-damp dispelling, the meridian dredging.Be used for rheumatic arthralgia, arthroncus.The physics and chemistry composition mainly contains sinomenine, has antiinflammatory, anti-muscle contracture effect.

Herba Taxilli: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable.

Semen Strychni (processed): removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.Be used for the stupid town of rheumatism numbness, paralysis and numbness.

Scorpio: the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.

Pheretima: the heat clearing away arresting convulsion, collateral dredging is relievingd asthma, diuresis.

Above-mentioned all medicines share, and the side separates as follows:

Radix Tripterygii Wilfordii, Caulis Sinomenii, Daphne giraldii Nitsche have dredge the meridian passage, eliminating stagnation, reducing swelling and alleviating pain effect, are monarch drug; Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Herba Asari, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Semen Strychni (processed) have expelling wind and removing dampness, resolving mass and removing the obstruction of the collateral effect, are ministerial drug; Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Herba Taxilli, Scorpio, Pheretima are as the through focus of priming, and can effectively control joint deformity is adjuvant drug; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription in order to reduce the toxicity of Radix Tripterygii Wilfordii, Semen Strychni, is messenger drug.Above-mentioned all medicine compatibilities have reducing swelling and alleviating pain, activating collaterals and eliminating stagnation effect, rheumatism, rheumatoid arthritis had significant therapeutic effect,

For showing therapeutic effect of the present invention, carried out clinical trial, accept rheumatoid arthritis patient 38 examples altogether for medical treatment, comprise male 18 examples, women 20 examples, wherein 31-40 year has 22 examples, 41-50 year 10 examples are arranged, 51-65 year 6 examples are arranged, it is professional cadre that 18 people are wherein arranged, 20 people are the peasant, little joint migration pain such as in various degree finger, wrist, toe are all arranged, the symptom that ankylosis, limitation of activity are all arranged, subcutaneous nodule appears in about 20% case, and wherein an example is the rheumatoid myocarditis.Above-mentioned case with water decoction treatment of the present invention, is treated a month result and seen Table 1.

Water decoction of the present invention has significant inhibitory effect to adjuvant-induced arthritis due to rat Ovum Gallus domesticus album, the formaldehyde, and reduces rat adrenal gland cholesterol level, treats that 17-hydroxyl skin ash steroid content significantly raises in effective patient's urine.Give rats by intraperitoneal injection with the present invention 70% ethanol preserved material, experiment showed, significant analgesic activity, 0.19,0.095, the analgesia of 0.048g/Kg renders a service the analgesia that has surpassed morphine 12,6,3mg/Kg respectively and render a service through electricity irritation Mus tail method.

The specific embodiment

Further specify effect of the present invention below in conjunction with concrete case.

Case one, Zhang Chunmei, woman, 39 years old.First visit in July, 2004, the patient in February, 2003 since go out to drench with rain after, soon the morbidity.Felt at that time that brothers' acid was bloated, brothers refer to the toe joint joint stuffiness, and brothers refer to toe joint pain immediately, and to get up the back morning obviously, movable slightly back is adorned gradually light especially.At local hospital diagnosis is rheumatoid arthritis, and gives the rheumatism pain management, month surplus obvious curative effects that do not have of taking medicine.With further checking to the People's Hospital, city, still be diagnosed as rheumatoid arthritis, treat half a year, unsatisfactory curative effect.When examining, patient's face is indifferent, painful expression, self-induction brothers' pain unbearably, hands can not be clenched fist, walking disorder.Red tongue, greasy fur are yellow slightly, deep-rolling pulse.Tcm diagnosis is the wind and cold arthromyodynia.Should be with the resolving mass and removing the obstruction of the collateral pain relieving, the warming the meridian that dispels the wind dehumidifying is main.

One pair of decoction consists of: Radix Gentianae Macrophyllae 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, refreshing teacher fiber crops 15g, Radix Saposhnikoviae 15g, Herba Asari 6g, Radix Aconiti Preparata 15g, Radix Aconiti Kusnezoffii Preparata 15g, Radix Tripterygii Wilfordii 10g, Caulis Sinomenii 30g, Herba Taxilli 30g, Semen Strychni (processed) 3g, Scorpio 10g, Pheretima 10g, Radix Glycyrrhizae 10g, other adds Semen Coicis 30g.Be decocted in water for oral dose.

Obeyed altogether 3 months, every day potion, transference cure.Follow up a case by regular visits to not recurrence again in 2 years

Case two, Xin Aiyun, woman, 48 years old.First visit in August, 2006, the patient had a rest on the concrete floor in oneself institute in July, 2006, and is sleeping accidentally, just it is miserable to feel whole body after waking up, and promptly and the trick ache refers to that toe joint is very painful, is diagnosed as rheumatoid arthritis in the People's Hospital, city, and with medication treatment, the moon of taking medicine is surplus not good, the symptom aggravation.Patient suffering's expression when examining, finger-joint swelling, the toes joint can not land, difficulty in walking.Red tongue, smooth tongue, the fine and smooth tcm diagnosis of stringy pulse: wind and cold arthromyodynia (liver-kidney yin deficiency) gives decoction plus-minus of the present invention treatment.

One pair of decoction consists of: Radix Gentianae Macrophyllae 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, refreshing teacher fiber crops 15g, Radix Saposhnikoviae 15g, Herba Asari 6g, Radix Aconiti Preparata 15g, Radix Aconiti Kusnezoffii Preparata 15g, Radix Tripterygii Wilfordii 10g, Caulis Sinomenii 30g, Herba Taxilli 30g, Semen Strychni (processed) 3g, Scorpio 10g, Pheretima 15g, Radix Glycyrrhizae 10g, other adds Rhizoma Polygonati Odorati 30g, Fructus Lycii 15g, Radix Paeoniae Alba 30g.Be decocted in water for oral dose.

Obey 3 first quarter moons altogether, every day potion, symptom all disappears, check is normal, follows up a case by regular visits to and does not have recurrence so far.

Table 1 treatment by Chinese herbs group of the present invention (totally 38 examples)

Treatment time the sky	Produce effects		Take a turn for the better		Invalid		Effective percentage
								Case load	Obvious effective rate	Case load	Improvement rate	Case load	Inefficiency
	10	10	26.3	20	52.6	8								21.1	78.9
20							15	39.5	18	47.4	5	13.1	86.9
	30	25	65.8	12	31.6	1								2.6	97.4

Claims (1)

1, a kind of decoction for treating arthritis is characterized in that, its one pair of decoction mainly is made according to the Chinese medicine boiling method by the Chinese medicine ingredients of following weight:

Radix Gentianae Macrophyllae 15g;

Rhizoma Et Radix Notopterygii 15g;

Radix Angelicae Pubescentis 15g;

Daphne giraldii Nitsche 15g;

Radix Saposhnikoviae 15g;

Herba Asari 6g;

Radix Aconiti Preparata 15g;

Radix Aconiti Kusnezoffii Preparata 15g;

Radix Tripterygii Wilfordii 10g;

Caulis Sinomenii 30g;

Herba Taxilli 30g;

Semen Strychni (processed) 3g;

Scorpio 6-10g;

Pheretima 10-15g;

Radix Glycyrrhizae 5-10g.