CN101716287B - Medicament for mainly treating arthromyodynia negative of rheumatoid factor and preparation method thereof - Google Patents

Medicament for mainly treating arthromyodynia negative of rheumatoid factor and preparation method thereof Download PDF

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Publication number
CN101716287B
CN101716287B CN2009102278843A CN200910227884A CN101716287B CN 101716287 B CN101716287 B CN 101716287B CN 2009102278843 A CN2009102278843 A CN 2009102278843A CN 200910227884 A CN200910227884 A CN 200910227884A CN 101716287 B CN101716287 B CN 101716287B
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rheumatoid factor
parts
medicament
medicine
radix
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CN101716287A (en
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马继龙
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Abstract

The invention relates to the field of traditional Chinese medicines, in particular to a medicament for treating rheumatism mainly with negative rheumatoid factor and a preparation method thereof. The invention solves the problem that the existing medicament and method for treating the rheumatism mainly with negative rheumatoid factor have various defects. The medicament for treating the rheumatism mainly with the negative rheumatoid factor comprises the following raw materials by weight parts: 25 to 35 parts of Astragalus root, 15 to 25 parts of thunder god vine, 3 to 6 parts of rhizoma gastrodiae, 3 to 6 parts of shizandra berry, 0.37 to 0.56 part of aspirin, 20 to 30 parts of radix gentianae macrophyllae and 8 to 10 parts of Pheretima. The medicaments are combined for use, and are mutually promoted, and the medicament has the efficacy of fast easing and eliminating symptoms and dispelling rheumatoid factor, treats both principal and secondary aspect of diseases, has special effects and does not has any toxic side effects.

Description

Treatment migratory arthralgia disease is main medicine and method for preparing with the rheumatoid factor negative
Technical field
The present invention relates to the field of Chinese medicines, be specially a kind of medicine and method for preparing that migratory arthralgia disease is the master with the rheumatoid factor negative of treating.
Background technology
Arthrodynia of extremities that migratory arthralgia refers to cause because of intrusion of pathogenic wind-cold-dampness on the Chinese medicine or numb disease; In town and country is one of commonly encountered diseases, and general many by due to the acute and chronic damage, migratory arthralgia disease is that master's disease incidence is in rising trend with the rheumatoid factor negative; Generally adopt methods such as having Western medicine, beat anesthesia needle, the local lysis of small needle knife to treat now; Western medicine hormones commonly used eases pain, and can only play the therapeutic effect of short time, and the untoward reaction of hormone medicine is more; Have only effect in short-term and make anesthesia needle, the drug level height can increase the weight of the adhesion and the inflammatory reaction of affected part; The local lysis of small needle knife is a kind of invasive surgical after all, and the patient is difficult for accepting, and misery is bigger, also has certain risk, if careless manipulation can injure nerve and blood vessel, brings body & mind painful to the patient, increases the weight of financial burden.
Summary of the invention
The present invention is the problem that there are many defectives in main medicine and method with the rheumatoid factor negative in order to solve existing treatment migratory arthralgia disease, provides a kind of and can alleviate rapidly, symptomatolytic treatment migratory arthralgia disease with the rheumatoid factor negative is main medicine and method for preparing.
The present invention adopts following technical scheme to realize: treatment migratory arthralgia disease is main medicine with the rheumatoid factor negative; Raw material by following parts by weight is processed: Radix Astragali 25-35 part, Radix Tripterygii Wilfordii 15-25 part, Rhizoma Gastrodiae 3-6 part; Fructus Schisandrae Chinensis 3-6 part; Aspirin 0.37-0.56 part, Radix Gentianae Macrophyllae 20-30 part, Pheretima 8-10 part.This medicine is is main limbs joint and muscular soreness, numbness to be specially rheumatoid factor negative that wind, wet, qi depression to blood stasis etc. cause because of migratory arthralgia disease, weighing, joint stuffiness; Even the scorching hot grade in joint is one type of disease of primary symptom; Have promoting flow of QI and blood, heat clearing away relieving convulsion, suppressing the hyperactive liver to relieve the wind syndrome, tendons relaxing and meridians dredging, reducing swelling and alleviating pain performance, play prevention and therapeutical effect preferably.
In the said medicine, the Radix Astragali: sweet in the mouth, slightly warm in nature, ability invigorating the spleen and replenishing QI, tonifying the lung consolidating superficial resistance, inducing diuresis to remove edema; Be used for deficiency of spleen-QI and stomach-QI, deficiency of spleen-QI, sinking of QI of middle-JIAO, visceroptosis (proctoptosis, uterine prolapse, gastroptosis etc.), insufficiency of lung-QI; Cough with asthma is losed heart, and spontaneous sweating due to deficiency of QI is easy to flu, deficiency of vital energy edema, dysuria; Insufficiency of vital energy and blood, anemia is sallow, or numb limbs and tense tendons, or skin infection, creation are difficult for healing, quench one's thirst (diabetes); Radix Tripterygii Wilfordii: hardship, suffering, big poison, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain, parasite killing detoxifcation; Be used for main classes rheumatic arthritis, rheumatic arthritis, glomerulonephritis, nephrotic syndrome, lupus erythematosus, mouthful xerophthalmia scheorma syndrome; Behcet disease, eczema, psoriasis, leprosy, scabies, stubborn dermatitis; Rhizoma Gastrodiae: property is flat, sweet in the mouth, and the suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion, it is dizzy to be used for the treatment headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, diseases such as tetanus; Fructus Schisandrae Chinensis: sweet in the mouth, acid, warm in nature, the ability supplementing QI for promoting the production of body fluid, the kidney invigorating is nourished heart; Restrain astringent or styptic treatment for spontaneous sweatingly, be used for deficiency of vital energy Tianjin and hinder, the tired hyperhidrosis of body, the cardiopalmus of losing heart, breathing with cough due to insufficiency of lung-QI or the deficiency of both the lung and kidney; Or breath with cough with the passing of time, the lung qi consumption is hindered insufficiency of heart-YIN, severe palpitation, insomnia forgetfulness; Instability of kidney QI, seminal emission, frequent micturition, or asthenia of both the spleen and kidney, incessant chronic diarrhea; Aspirin: analgesic, analgesia is used for antiinflammatory, rheumatism, arthritis, antithrombotic, mucocutaneous lymph node syndrome; Radix Gentianae Macrophyllae: suffering, hardship, flat, return through, return stomach, liver, gallbladder meridian is used for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, infantile malnutrition heating; Pheretima: cold in nature, salty in the mouth, the heat clearing away arresting convulsion, collateral dredging is relievingd asthma, and diuresis is used for the unconsciousness due to high fever infantile convulsion and twitches, joint paralysis, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension.
The method for preparing of medicine according to the invention is following: dry after choosing the medical material decontamination (1); (2) Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively and endure, be dried into medicated powder at 50 ℃-70 ℃ respectively then to paste; (3) will go up in the step each medicated powder and add aspirin and fully mix and stir, can process the various dosage forms of medicine of the present invention according to conventional method, like capsule, tablet, powder or pill.
All medicine combinations are used, and mutually promote, and have rapid alleviation, eliminate symptom, dispel the effect of rheumatoid factor, and treating both the principal and secondary aspects of a disease, special effect, without any side effects.Through 232 patients are treated, statistical result is: medicine according to the invention can reach more than 97% the effective percentage of treatment rheumatoid disease, and cure rate can reach more than 92%.
Model case
1, Mrs Ren, 68 years old, suffering from migratory arthralgia disease was main in 2002 with rheumatoid factor negative, took medicine of the present invention and checked after 70 days, all transference cures recover normal, follow up a case by regular visits to so far and do not see recurrence.
2, Mr. Niu, 68 years old, in calendar year 2001 conscious extremities joint the. fugitive pain, redness, numbness, distortion joint stuffiness, qi depression to blood stasis disease such as stiff; After be diagnosed as migratory arthralgia disease, take one week of medicine of the present invention back pain, the red and swollen improvement, the joint joint stuffiness is not seen obvious change; Take the transference cure of pain after half a year, swelling subsequently continuously; The joint of distortion alleviates to some extent, and activity is checked after three months and do not seen recurrence freely.
3, Mrs Duan 58 years old, the symptom of extremities joint pain, redness, limitation of activity occurred in 2003; Being diagnosed as migratory arthralgia disease is main with qi depression to blood stasis; Take two week of medicine of the present invention back pain, rednesses obviously alleviate, and are movable unrestricted, continue to take all transference cures after half a year.
4, Mrs Wang 65 years old, because of unfavorable 5 years of double knee joint, stiff activity in two ankle swelling pain companion morning, once sought medical advice to how tame hospital; Be diagnosed as migratory arthralgia disease, patient main suit gives heavy dose of hormone medicine treatment respectively, and symptom is alleviated fast; But drug effect symptom is later shown effect repeatedly, and increases the weight of gradually, takes medicine of the present invention after fortnight; Arthralgia, morning, deadlock alleviated, and continued to take transference cure after half a year, and activity freely.
5, Mrs Du, 42 years old, right carpal joint obviously swelled and ache and has a surplus half a year, and patient left side carpal joint also swells and ache, but symptom is lighter, and other joints are fair, and whenever to cold season or when overcast and rainy, pain increases the weight of, and takes medicine of the present invention and checks after four months and do not see recurrence.
The specific embodiment
Embodiment 1: every part is 1 gram
Treatment migratory arthralgia disease is main medicine with the rheumatoid factor negative, is processed by the raw material of following parts by weight: the Radix Astragali 25 grams, Radix Tripterygii Wilfordii 15 grams, Rhizoma Gastrodiae 3 grams, Fructus Schisandrae Chinensis 3 grams, aspirin 0.37 gram, Radix Gentianae Macrophyllae 20 grams, Pheretima 8 grams.Method for preparing may further comprise the steps: dry after choosing the medical material decontamination; The Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively endure, be dried into medicated powder at 50 ℃ respectively then to paste; To go up in the step each medicated powder and add aspirin and fully mix and stir, promptly can be made into capsule.
Embodiment 2: every part is 1 liang
Treatment migratory arthralgia disease is main medicine with the rheumatoid factor negative, is processed by the raw material of following parts by weight: 35 liang of the Radixs Astragali, 25 liang of Radix Tripterygii Wilfordiis, 6 liang in Rhizoma Gastrodiae, 6 liang of Fructus Schisandrae Chinensis, 0.56 liang of aspirin, 30 liang of Radix Gentianae Macrophyllae, 10 liang of Pheretimas.Method for preparing may further comprise the steps: dry after choosing the medical material decontamination; The Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively endure, be dried into medicated powder at 70 ℃ respectively then to paste; To go up in the step each medicated powder and add aspirin and fully mix and stir, promptly can be made into tablet.
Embodiment 3: every part is 1 jin
Treatment migratory arthralgia disease is main medicine with the rheumatoid factor negative, is processed by the raw material of following parts by weight: 30 jin of the Radixs Astragali, 20 jin of Radix Tripterygii Wilfordiis, 5 jin in Rhizoma Gastrodiae, 4 jin of Fructus Schisandrae Chinensis, 0.48 jin of aspirin, 25 jin of Radix Gentianae Macrophyllae, 9 jin of Pheretimas.Method for preparing may further comprise the steps: dry after choosing the medical material decontamination; The Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively endure, be dried into medicated powder at 60 ℃ respectively then to paste; To go up in the step each medicated powder and add aspirin and fully mix and stir, promptly can be made into pill.
Embodiment 4: every part is 1 kilogram
Treatment migratory arthralgia disease is main medicine with the rheumatoid factor negative, is processed by the raw material of following parts by weight: 26 kilograms of the Radixs Astragali, 24 kilograms of Radix Tripterygii Wilfordiis, 4 kilograms in Rhizoma Gastrodiae, 5 kilograms of Fructus Schisandrae Chinensis, 0.54 kilogram of aspirin, 22 kilograms of Radix Gentianae Macrophyllae, 8 kilograms of Pheretimas.Method for preparing may further comprise the steps: dry after choosing the medical material decontamination; The Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively endure, be dried into medicated powder at 53 ℃ respectively then to paste; To go up in the step each medicated powder and add aspirin and fully mix and stir, promptly can be made into tablet.

Claims (2)

1. treat the medicine that migratory arthralgia disease is the master with the rheumatoid factor negative for one kind, it is characterized in that: the raw material by following parts by weight is processed: Radix Astragali 25-35 part, Radix Tripterygii Wilfordii 15-25 part; Rhizoma Gastrodiae 3-6 part, Fructus Schisandrae Chinensis 3-6 part, aspirin 0.37-0.56 part; Radix Gentianae Macrophyllae 20-30 part, Pheretima 8-10 part.
2. preparing treatment migratory arthralgia disease as claimed in claim 1 is the method for master's medicine with the rheumatoid factor negative, it is characterized in that: may further comprise the steps:
(1) dries after choosing the medical material decontamination;
(2) Radix Astragali, Radix Tripterygii Wilfordii, Rhizoma Gastrodiae, Fructus Schisandrae Chinensis, Radix Gentianae Macrophyllae, Pheretima are added decocting respectively and endure, be dried into medicated powder at 50 ℃-70 ℃ respectively then to paste;
(3) will go up in the step each medicated powder and add aspirin and fully mix and stir, promptly can be made into medicine of the present invention.
CN2009102278843A 2009-12-20 2009-12-20 Medicament for mainly treating arthromyodynia negative of rheumatoid factor and preparation method thereof Expired - Fee Related CN101716287B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1283302C (en) * 2004-05-14 2006-11-08 姚秀芸 Medicament for treating rheumatoid arthritis and artjritis pauperum
CN101062198A (en) * 2007-05-26 2007-10-31 李丰军 Decoction for treating arthritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1283302C (en) * 2004-05-14 2006-11-08 姚秀芸 Medicament for treating rheumatoid arthritis and artjritis pauperum
CN101062198A (en) * 2007-05-26 2007-10-31 李丰军 Decoction for treating arthritis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
任志宏等.浅谈庞学丰分阶段辨治类风湿关节炎的临床经验.《内蒙古中医药》.2008,(第8期),22-23. *
张天静等.阿司匹林的用法与剂量.《类风湿病的诊断与治疗》.黑龙江科学技术出版社,1987,55. *
肖诚等.类风湿关节炎类风湿因子阴性和阳性寒热证候患者外周血CD_4_T细胞基因差异表达研.《中国中西医结合杂志》.2006,第26卷(第8期),689-692. *

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