CN101301394A - Medicament for treating rheumatoid disease - Google Patents
Medicament for treating rheumatoid disease Download PDFInfo
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- CN101301394A CN101301394A CNA2008100553112A CN200810055311A CN101301394A CN 101301394 A CN101301394 A CN 101301394A CN A2008100553112 A CNA2008100553112 A CN A2008100553112A CN 200810055311 A CN200810055311 A CN 200810055311A CN 101301394 A CN101301394 A CN 101301394A
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Abstract
The invention relates to the pure Chinese traditional medicine field, in particular to a medicine for treating rheumatic diseases. The invention resolves problems that the prior Western medicines and Chinese traditional medicines for treating rheumatic diseases both have defects to some extent. The medicine of the invention is prepared by the following components in weight portions: 95 to 105 portions of prepared rhizome of rehmannia, 95 to 105 portions of Shengqi, 45 to 50 portions of big head atractylodes rhizome, 45 to 55 portions of epimedium, 48 to 58 portions of angelica, 15 to 25 portions of cinnamon, 15 to 25 portions of white mustard seed, 15 to 25 portions of Chinese ephedra and 15 to 25 portions of ginseng; all components are used together and mutually promoted, and the prepared rhizome of rehmanni, the epimedium, the Shengqi, the cinnamon, the ginseng and the angelica have the functions of invigorating qi and nourishing the blood and mildly reinforcing the kidney-yang; the big head atractylodes rhizome and the white mustard seed have the functions of invigorating the spleen and eliminating dampness and resolving phlegm and helping the joint; the Chinese ephedra has the functions of dispersing external arthralgia and not keeping pathogen factors. The whole formula has the advantages of having the reasonable compatibility of medicines, nourishing qi and the blood, warming yang and regulating yin, invigorating the spleen and eliminating dampness, mildly reinforcing the kidney-yang, activating blood circulation to dissipate blood stasis and diminishing inflammation and alleviating pain, along with the fast medicine effect, the short treatment period and the uneasy recrudescence; moreover, the medicine emphasizes on the treatment focusing on relieving both the secondary and primary symptoms, the healthy energy supporting and evil elimination and the function restoration.
Description
Technical field
The present invention relates to the pure field of Chinese medicines, be specially a kind of medicine for the treatment of atrophic diseases.
Background technology
Atrophic diseases be a kind of with arthroncus, pain, be deformed into the chronic autoimmune disease of cardinal symptom, be clinical comparatively difficult and complicated illness of seeing more, its disease cycle is longer, clinical manifestation is various, the cause of disease, pathogenesis more complicated.The traditional Chinese medical science thinks that cold, humidity, fatigue, wound and direct stimulation, malnutrition etc. all can become the inducement of primary disease, malnutrition, insufficiency of vital energy and blood, taste loss cause driving evil unable, exopathogen such as wind and cold humidity are availed oneself of the opportunity to get in, numbness resistance venation, multiple abscess joint and falling ill, show as muscle muscles and bones joint aches, numbness, cramp, swelling, even red and swollen distortion, weight person can cause the destruction of joint sclerotin, serious consequence such as cause joint deformity, amyotrophy, joint stuffiness, paralyse, can't take care of oneself has caused very big influence orthobiosis for people.
At present, because the etiology unknown of primary disease, medicines such as that doctor trained in Western medicine mainly adopts is analgesic, antiinflammatory, analgesia, be used to alleviate patient's disease symptoms, the development of control disease or destructive joint repaired, and can not fundamentally treat, existing medicine commonly used " controlling numbness looses ", " indometacin " etc., easily recur after all having drug withdrawal to some extent, grow the course of treatment, can lead to complications, side effect is big.In pure Chinese medicine Drug therapy process, can either the antiinflammatory calmness, possess immunosuppressant and immunoregulation effect again, be easy to take for a long time, to be that the state of an illness is unreasonable, prolonged do not heal the problem that runs into, and coagulation of QI-blood is not all right, and the meridians obturation is obstructed, and curative effect is slower.
Summary of the invention
The present invention is in order to solve in various degree problems that has above-mentioned shortcoming separately of existing Western medicine that is used for the treatment of atrophic diseases and Chinese medicine, and a kind of medicine of new treatment atrophic diseases is provided.
The present invention adopts following technical scheme to realize: a kind of medicine for the treatment of atrophic diseases, raw material by following weight ratio is made: Radix Rehmanniae Preparata 95-105 part, Radix Astragali 95-105 part, Rhizoma Atractylodis Macrocephalae 45-50 part, Herba Epimedii 45-55 part, Radix Angelicae Sinensis 48-58 part, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 15-25 part.
The optimum formula of medicine of the present invention is: 100 parts in Radix Rehmanniae Preparata, and 100 parts of Radix Astragali, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Herba Epimedii, 50 parts of Radix Angelicae Sinensis, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 20 parts.
The preparation method of medicine of the present invention is as follows: every flavor medicine is all according to after standards of pharmacopoeia and the processing of Chinese medicine processing standard, entry was soaked 15-20 minute, boil with big fire then, the little fire of reuse fried 30-40 minute, filter medicinal liquid, promptly can be made into various dosage forms, as capsule, tablet, powder, pill.
In the said medicine, Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature, function nourishing YIN and supplementing blood, vital essence replenishing and marrow benifiting.Control deficiency of YIN insufficiency of blood, the hollow institute of brains waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency extremely quenched one's thirst frequency of micturition, deafness, blurred vision, palpitation and insomnia, forgetful, night sweat etc.; Radix Astragali: nature and flavor with return through sweet temperature.Cure mainly invigorating QI to consolidate the body surface resistance, the diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, it is weak to be used for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration; Herba Epimedii: hot, sweet, temperature.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Be used for impotence and seminal emission, the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Radix Angelicae Sinensis: sweet, hot, temperature.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; Cortex Cinnamomi: extremely hot in nature, acrid in the mouth, sweet, it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, warming the meridian and promoting blood circulation; Semen Sinapis Albae: acrid in the mouth, temperature, nontoxic.Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison.Control cold syndrome of the stomach and tell food, trusted subordinate's pain, lung cold cough, arthralgia aggravated by cold, traumatic injury; Herba Ephedrae: hot, little hardship, temperature.The diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Be used for anemofrigid cold, uncomfortable in chest breathing with cough, edema due to wind pathogen edema; Radix Ginseng: sweet, little hardship, flat.Strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, and calms the nerves.Be used for weak body and prostration, the cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, heart failure, cardiogenic shock.
All medicines are used in combination, mutually promote, wherein, Radix Rehmanniae Preparata, Herba Epimedii, Radix Astragali, Cortex Cinnamomi, Radix Ginseng, Radix Angelicae Sinensis, benefiting QI and nourishing blood, warming and recuperating the kidney-YANG; The Rhizoma Atractylodis Macrocephalae, Semen Sinapis Albae, the spleen strengthening and damp drying, the sharp joint of reducing phlegm; Herba Ephedrae, the outer numbness of using pungent drugs for dispersion and bitter drugs for purgation, heresy is not stayed in tonification; Whole formula compatibility is reasonable, has benefiting vital QI and blood, the warming YANG nourishing YIN, the spleen strengthening and damp drying, warming and recuperating the kidney-YANG, eliminating evil reducing phlegm, blood circulation promoting and blood stasis dispelling, effects such as anti-inflammatory analgetic, the efficacy of a drug is rapid-action, treatment cycle is short, is difficult for recurrence, make disease easily move back, just easily answer, emphatically treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors and function reparation has significant curative effect to rheumatism, rheumatoid chronic disease, enhance immunity arranged, improve the curative effect of blood circulation.
In order further to show therapeutic effect of the present invention, carried out following clinical trial especially, random choose goes out 80 routine patients, cures 18 examples, produce effects 26 examples, effective 30 examples, invalid 6 examples, effective percentage reaches 92%, and the course of treatment is the shortest two months, and is the longest 6 months.
Model case
1, Zhao, man, 38 years old, Qian Chuan township, Hequ county, the extremities joint interruption swelled and ache 4 years, increased the weight of February, county hospital is diagnosed as rheumatoid arthritis, no subcutaneous nodule, two type joint swellings, tenderness, both hands symmetry 6 refers to that it is surplus to take the medicine moon of the present invention, doing well,improving, after took this medicine again 1 month, consolidate curative effect, followed up a case by regular visits to 1 year, the state of an illness does not recur;
2, Feng, woman, 40 years old, area just outside a city gate, Wuzhai County teacher suffers from surplus the rheumatoid 20 year, joint deformity, the slight atrophy of muscle, and the miserable pain of whole-body muscle, functional activity is limited, take medicine of the present invention after 2 months, the stiff time in morning shortens, and pain is extenuated, after consolidated again 1 month, symptom disappears substantially, follows up a case by regular visits to half a year, does not have recurrence.
3, Liu, woman, 39 years old, the tower people of Hequ county Liu family, extremities joint swelled and ache 5 years, increased the weight of 3 months, be diagnosed as rheumatoid arthritis through doctor trained in Western medicine, successively with antirheumatic and hospitalization, light when weighing during each arthralgia, outbreak was taken medicine of the present invention 3 months repeatedly, and each arthralgia obviously alleviates, can do slight work, continue to take this medicine 1 month, recovery from illness, follow up a case by regular visits to a year and a half, do not have recurrence.
4, Wang, the woman, 30 years old, suffered from surplus the rheumatic arthritis 10 year in style of writing town, area just outside a city gate, Hequ county, and the joint is distortion not, but amyotrophy, fall ill every year repeatedly, takes medicine of the present invention after three months, and curative effect is fine.
5, Zhai, woman, 31 years old, area just outside a city gate Town Government, whole body arthralgia, can not take care of oneself, wrist, refer to, knee joint, the enlargement of ankle joint symmetry, successively in the treatment of large hospitals such as province, county, but often outbreak repeatedly, take three first quarter moons of medicine of the present invention, symptom is clearly better, after consolidated again two months, be almost recovered.
The specific embodiment
Embodiment 1: every part is 1 gram
A kind of medicine for the treatment of atrophic diseases is made by the raw material of following weight ratio: Radix Rehmanniae Preparata 95 grams, Radix Astragali 95 grams, the Rhizoma Atractylodis Macrocephalae 45 grams, Herba Epimedii 45 grams, Radix Angelicae Sinensis 48 grams, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 15 grams, every flavor medicine all according to after standards of pharmacopoeia and the processing of Chinese medicine processing standard, soaked 15 minutes, boils with big fire then by entry, fried 30 minutes of the little fire of reuse, filter medicinal liquid, make capsule according to conventional concocting method then, take.
Embodiment 2: every part is 1 kilogram
A kind of medicine for the treatment of atrophic diseases is made by the raw material of following weight ratio: 105 kilograms in Radix Rehmanniae Preparata, 105 kilograms of Radix Astragali, 50 kilograms of the Rhizoma Atractylodis Macrocephalaes, 55 kilograms of Herba Epimedii, 58 kilograms of Radix Angelicae Sinensis, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 25 kilograms, every flavor medicine all according to after standards of pharmacopoeia and the processing of Chinese medicine processing standard, soaked 20 minutes, boils with big fire then by entry, fried 40 minutes of the little fire of reuse, filter medicinal liquid, make tablet according to conventional concocting method then, take.
Embodiment 3: every part is 1 liang
A kind of medicine for the treatment of atrophic diseases, make by the raw material of following weight ratio: 100 liang in Radix Rehmanniae Preparata, 100 liang of Radix Astragali, 50 liang of the Rhizoma Atractylodis Macrocephalaes, 50 liang of Herba Epimedii, 50 liang of Radix Angelicae Sinensis, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 20 liang.Every flavor medicine all according to after the processing of standards of pharmacopoeia and Chinese medicine processing standard, soaked 16 minutes by entry, boil with big fire then, fried 35 minutes of the little fire of reuse, filter medicinal liquid, make powder according to conventional concocting method then, take.
Embodiment 4: every part is 1 jin
A kind of medicine for the treatment of atrophic diseases is made by the raw material of following weight ratio: 98 jin in Radix Rehmanniae Preparata, 105 jin of Radix Astragali, 48 jin of the Rhizoma Atractylodis Macrocephalaes, 45 jin of Herba Epimedii, 55 jin of Radix Angelicae Sinensis, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 15 jin, every flavor medicine all according to after standards of pharmacopoeia and the processing of Chinese medicine processing standard, soaked 18 minutes, boils with big fire then by entry, fried 37 minutes of the little fire of reuse, filter medicinal liquid, make pill according to conventional concocting method then, take.
Claims (2)
1, a kind of medicine for the treatment of atrophic diseases is characterized in that being made by the raw material of following weight ratio:
Radix Rehmanniae Preparata 95-105 part, Radix Astragali 95-105 part, Rhizoma Atractylodis Macrocephalae 45-50 part, Herba Epimedii 45-55 part, Radix Angelicae Sinensis 48-58 part, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 15-25 part.
2, according to right
Ask 1 described a kind of medicine for the treatment of atrophic diseases, it is characterized in that making by the raw material of following weight ratio:
100 parts in Radix Rehmanniae Preparata, 100 parts of Radix Astragali, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Herba Epimedii, 50 parts of Radix Angelicae Sinensis, Cortex Cinnamomi, Semen Sinapis Albae, Herba Ephedrae, Radix Ginseng are respectively 20 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100553112A CN101301394B (en) | 2008-06-27 | 2008-06-27 | Medicament for treating rheumatoid disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100553112A CN101301394B (en) | 2008-06-27 | 2008-06-27 | Medicament for treating rheumatoid disease |
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| Publication Number | Publication Date |
|---|---|
| CN101301394A true CN101301394A (en) | 2008-11-12 |
| CN101301394B CN101301394B (en) | 2011-01-26 |
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| CN2008100553112A Expired - Fee Related CN101301394B (en) | 2008-06-27 | 2008-06-27 | Medicament for treating rheumatoid disease |
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| CN (1) | CN101301394B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189865A (en) * | 2014-09-26 | 2014-12-10 | 陈维香 | Traditional Chinese medicine preparation for gonitis and preparation method of traditional Chinese medicine preparation |
| CN108403906A (en) * | 2018-06-05 | 2018-08-17 | 广东安诺药业股份有限公司 | A kind of pharmaceutical composition and preparation method thereof of prevention rheumatoid arthritis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1032622C (en) * | 1993-01-19 | 1996-08-28 | 王来运 | Medicinal liquid for relaxing muscles and tendons and activating collaterals |
| CN1193775C (en) * | 2000-12-30 | 2005-03-23 | 李毅 | Rheumatoid disease treating capsule |
-
2008
- 2008-06-27 CN CN2008100553112A patent/CN101301394B/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189865A (en) * | 2014-09-26 | 2014-12-10 | 陈维香 | Traditional Chinese medicine preparation for gonitis and preparation method of traditional Chinese medicine preparation |
| CN108403906A (en) * | 2018-06-05 | 2018-08-17 | 广东安诺药业股份有限公司 | A kind of pharmaceutical composition and preparation method thereof of prevention rheumatoid arthritis |
| CN108403906B (en) * | 2018-06-05 | 2021-02-23 | 广东安诺药业股份有限公司 | Pharmaceutical composition for preventing and treating rheumatoid arthritis and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN101301394B (en) | 2011-01-26 |
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