CN101129697A

CN101129697A - Orally taken traditional Chinese medicine composition for treating atrophic arthritis

Info

Publication number: CN101129697A
Application number: CNA2007100165517A
Authority: CN
Inventors: 于春杰
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-08-23
Filing date: 2007-08-23
Publication date: 2008-02-27

Abstract

The invention discloses an oral administration pharmaceutical composition for treating rheumatoid arthritis, wherein the active constituents include the following raw material herbs (by weight portion): Chinese angelica root 15, prepared rhizome of rehmannia 15, siberian cocklebur fruit 10, hornet nest 10, Garter snake 20, wood louse 10, buthus martensi kirsch 3, centipede 6, barren wort 20, spatholobus stem 25, coralbean bark 15 and coralbean bark 16. The medicament should be decocted in water for the oral dose.

Description

A kind of Chinese medicine composition of orally taken for curing rheumatoid arthritis

Technical field

The present invention relates to a kind of Chinese medicine composition, is a kind of Chinese medicine composition of orally taken for curing rheumatoid arthritis specifically, belongs to the field of Chinese medicines.

Background technology

Rheumatoid arthritis is a kind of extensive and obstinate chronic disease, and local ankylosis pain is only arranged when the patient's condition is slight, then can cause the joint swelling and pain and the damage of whole body when serious, even cause deformity.

This sick cause of disease is invaded articular cavity for infector (antibacterial, virus, mycoplasma etc.) is arranged earlier, can form antigen antibody complex, and antibody promptly changes allosome into, stimulates plasma cell will produce new antibody again, rheumatoid factor that Here it is.Rheumatoid factor and immunoglobulin are combined into immune complex, cause inflammation in synovium of joint and the articular cavity, thereby inspire neutrophilic granulocyte, macrophage and synovial cell's phagocytosis.The cell of these phagocytic immunity complex is called RA cell.In order to eliminate this immune complex, RA cell the oneself break, and discharges a large amount of enzymes, and these enzymes comprise multiple acid hydrolase, and they destroy the substrate of synovial membrane, joint capsule, cartilage and subchondral bone specially, causes the local failure in joint.Suffer from cold, humidity, fatigue, psychic trauma, malnutrition, wound etc., often be the risk factor of primary disease.

Rheumatoid arthritis main clinical performance be local joint smaller ache and stiff, the state of an illness is alternately alleviated and recurrence, increase the weight of gradually, often with fatigue and weakness, loss of appetite, heating, anemia, General Symptoms such as lose weight.Mainly show as following some: morning stiff phenomenon and ankylosis; Arthroncus or pain; The joint of getting involved; Arthritis shifts; Joint crepitus; Function of joint and limitation of activity.

The Therapeutic Method of rheumatoid arthritis roughly is divided into two kinds: (Salicylate, aspirin are for treating the choice drug of rheumatoid arthritis for physical therapy (local thermotherapy, hot bath, evaporation therapy etc.) and Drug therapy.Indometacin is arranged again, this acid of isobutyl phenylpropyl alcohol, 17-hydroxy-11-dehydrocorticosterone, medicines such as Radix Tripterygii Wilfordii all have certain curative effect.) but these Therapeutic Method can only relief of symptoms, can not fundamentally reach the purpose of treatment.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine composition of orally taken for curing rheumatoid arthritis, it has overcome the deficiency of above-mentioned Therapeutic Method, fundamentally treats rheumatoid arthritis.

Technical scheme of the present invention is: the Chinese medicine composition of this kind orally taken for curing rheumatoid arthritis is characterized in that the raw material of Chinese medicine of making the medicine active ingredient by its weight portion is: Radix Angelicae Sinensis 15, Radix Rehmanniae Preparata 15, Fructus Xanthii 10, Nidus Vespae 10, Zaocys 20, Eupolyphaga Seu Steleophaga 10, Scorpio 3, Scolopendra 6, Eumeces Chinensis 30, Herba Epimedii 20, Caulis Spatholobi 25, Cortex erythrinae 15 and Radix Aconiti Preparata 6.

Usage: be decocted in water for oral dose 1 dose of day clothes.

Pharmacological action: Radix Angelicae Sinensis: sweet Wen Zhirun, be the key medicine of enriching blood, enrich blood and invigorate blood circulation, holding concurrently again can dispersing cold for relieving pain.Radix Rehmanniae Preparata: the both kind YIN nourishing of enriching blood, again can vital essence replenishing and marrow benifiting, cure mainly the cloudy disease of losing oligospermia of all blood deficiency.Major function nourishing the blood and yin, vital essence replenishing and marrow benifiting are used for blood deficiency and yellow complexion, dizzy, cardiopalmus.Fructus Xanthii: Fructus Xanthii, its property of medicine are sweet in the mouth, and hardship is warm in nature, and the rheumatism of loosing is used for rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.Nidus Vespae: the flat sweet in the mouth of property, return the stomach warp, have dispel the wind, the effect of counteracting toxic substances, parasite killing, pain relieving, warming the kidney to activate YANG.Zaocys: dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.Eupolyphaga Seu Steleophaga: but removing blood stasis, removing mass, collateral dredging, reason are hindered effects such as treatment traumatic injury.Scorpio: cure mainly that rubella and apoplexy, hemiplegia, facial hemiparalysis, language are puckery, tetany etc.Scolopendra: have expel wind to dredge collateral analgesic effect preferably.Herba Epimedii: the waist hip is unable, rheumatic arthralgia.Caulis Spatholobi: blood circulation promoting and blood stasis dispelling, it is warm in nature, bitter in the mouth, sweet.Return liver, kidney channel.Have enrich blood, invigorate blood circulation, the effect of collateral dredging.Cortex erythrinae: removing damp-heat.Radix Aconiti Preparata: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

After the present invention made up said medicine, its drug effect had synergism, has obtained remarkable result in the therapeutic process of rheumatoid arthritis, and through 106 routine clinical verifications, radical rate reaches more than 90%, and model case is as follows:

Case 1: patient Lee, the woman, 58 years old, on March 20th, 06 examined.

Once be caught in the rain, the burst hyperpyrexia, all blood pain, after certain hospitalize, heating is alleviated.But bilateral upper limb pain day by day increases the weight of, and the arthroncus joint stuffiness is invalid and examine through multi-treatment.Existing disease sees that two upper limb joints are swollen painful, and the pain increased when wind and cold or Changes in weather whenever, enlargement distortion, joint stuffiness.Elbow joint atrophy, tetanic can not be praised, be bent and stretched.The companion sees giddy, cold, the inappetence of fear, and is uncomfortable in chest weak, and tongue is greasy in vain, the deep pulse stringy and rolling pulse.Give Drug therapy of the present invention, take medicine 55 doses, all disease knowing are removed, and disease is fully recovered.Follow up a case by regular visits to after 1 year, both hands are movable as usual strong, and can be competent at heavy physical work, and body is strong refreshing prosperous.

Case 2: patient Wang, the woman, 39 years old, on August 6th, 06 examined.

Main cause: extremities joint pain, enlargement is stiff, heating, limitation of activity 1 year is surplus, increases the weight of 3 months, moves in " rheumatoid arthritis " in Nikkei outpatient service in Augusts 6 in 2006.The patient right hand articulations digitorum manus pain occurs in no inducement in 2005, and swelling is gradually capable property and increases the weight of.Once treated (concrete therapeutic scheme is not quite clear) in the locality, pain relief, but function of joint is limited, can't take care of oneself.Take before the medicine of the present invention symptom and be extremities joint pain, swelling, stiff, heating, limitation of activity, red tongue, yellow and greasy fur, slippery and rapid pulse, received since the idiopathy can, the peace of sleeping, two just accent.Through Comprehensive Treatment 50 days, state of an illness control, all arthroncuss are eliminated, and skin temperature is normal, and all fingers (toe) joint stiff elimination in morning lived and can be taken care of oneself.After advising it to leave hospital, continue to take this Chinese medicine, and strengthen limb function rehabilitation and take exercise, consolidate curative effect.Follow up a case by regular visits to after 2 years, do not have recurrence.

Case 3: patient Liu, the man, 52 years old, on July 1st, 06 examined.

Rheumatoid arthritis is suffered from readme, and the phenomenon of joint deadlock in morning, distending pain was just arranged before 5 years, and lower limb can not be squatted down, and it is painstaking to sit down, and if the back no one that sits down assist basic station in not.Finger swells and ache and can not hold thing, and meal also is unable to finish, and has been provincial hospital once and has gone to a doctor, and money has been spent more than 30,000, though take a turn for the better to some extent, still pain stiff after the drug withdrawal, medicine recurs once stopping.The state of an illness slowly is more and more serious, especially to the cloudy day rain, time day cyclostrophic cold, just severely than usual painful, special be afraid of cool.Introduce through others, begin to take this medicine in May, 2004, and it is very unobvious just to have begun effect, even situation about increasing the weight of once occurring.After 10 days, pain begins to alleviate, and after 30 days, pain has just disappeared, and morning, deadlock also was clearly better.Took continuously again 40 days afterwards, all symptoms have all disappeared, and drug withdrawal was recurred so far later on never again.Legs and feet are flexible now, do not have any difference with the normal person.

The specific embodiment

Embodiment one: a kind of Chinese medicine composition of orally taken for curing rheumatoid arthritis, and the raw material of Chinese medicine of making the medicine active ingredient is (unit by its weight; Gram): Radix Angelicae Sinensis 15, Radix Rehmanniae Preparata 15, Fructus Xanthii 10, Nidus Vespae 10, Zaocys 20, Eupolyphaga Seu Steleophaga 10, Scorpio 3, Scolopendra 6, Eumeces Chinensis 30, Herba Epimedii 20, Caulis Spatholobi 25, Cortex erythrinae 15 and Radix Aconiti Preparata 6.

Usage: be decocted in water for oral dose 1 dose of day clothes.

Claims

1. the Chinese medicine composition of an orally taken for curing rheumatoid arthritis is characterized in that, the raw material of Chinese medicine of making the medicine active ingredient by its weight portion is: Radix Angelicae Sinensis 15, Radix Rehmanniae Preparata 15, Fructus Xanthii 10, Nidus Vespae 10, Zaocys 20, Eupolyphaga Seu Steleophaga 10, Scorpio 3, Scolopendra 6, Eumeces Chinensis 30, Herba Epimedii 20, Caulis Spatholobi 25, Cortex erythrinae 15 and Radix Aconiti Preparata 6.