CN100512867C - Traditional Chinese medicinal preparation for treating rheumatic arthritis, rheumatoid oarthritis, intervertebral disc and ischialgia neuralgia - Google Patents
Traditional Chinese medicinal preparation for treating rheumatic arthritis, rheumatoid oarthritis, intervertebral disc and ischialgia neuralgia Download PDFInfo
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Abstract
一种治疗风湿类风湿性关节炎椎间盘突出坐骨神经痛中药制剂,其主要特点是采用制马钱子、甘草、当归、血竭、桂枝、制川乌、防己、杜仲、透骨草、藿香等共十八种中药研细制备成块剂、散剂或丸剂。本药具有祛风除湿、活血通络、化瘀解毒、和胃健脾、益气止痛、发汗解表、利水消肿、补肝肾强筋骨等功能。适用于风湿、类风湿性关节炎、肩周炎、妇女产后风、跟骨刺、骨质增生或腰椎间盘突出、坐骨神经痛等四肢麻木、腰腿疼痛。本药具有治愈率高、治疗范围广、疗效迅速、除根治本等显著特点。A traditional Chinese medicine preparation for treating rheumatic rheumatoid arthritis, disc herniation and sciatica. A total of 18 kinds of traditional Chinese medicines are finely ground and prepared into blocks, powders or pills. This medicine has the functions of expelling wind and dehumidification, promoting blood circulation and dredging collaterals, removing blood stasis and detoxification, harmonizing stomach and invigorating spleen, replenishing qi and relieving pain, sweating and relieving exterior syndrome, promoting water and reducing swelling, nourishing liver and kidney and strengthening muscles and bones. It is suitable for rheumatism, rheumatoid arthritis, frozen shoulder, women's postpartum wind, heel spurs, hyperosteogeny or lumbar disc herniation, sciatica and other limb numbness, waist and leg pain. The medicine has the notable characteristics of high cure rate, wide range of treatment, rapid curative effect, eliminating the root cause and treating the root cause.
Description
技术领域 technical field
本发明属于中药技术领域,尤其是一种治疗风湿、类风湿性关节炎、腰椎间盘突出及坐骨神经痛的中药制剂。The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating rheumatism, rheumatoid arthritis, lumbar intervertebral disc herniation and sciatica.
背景技术 Background technique
风湿、类风湿性关节炎、骨质增生、腰椎间盘突出、肩周炎、产后风、坐骨神经痛等,中医认为均属于风寒湿痹症范畴。目前治疗上述病症的主要方法有手术切除、牵引、理疗、针灸、外用药物、内服中药或打封闭针或服用西药激素类药物等。手术治疗有危险性高、费用大、治愈效果差,且术后恢复期长等缺点。针灸治疗轻微病症有一定治疗效果,但容易复发,治疗效果一般。外用药物如普通贴剂,也只是能拔皮肤表面之毒,对深入内脏之风邪湿痹却无能为力。牵引和理疗不仅治疗周期长,而且只治表不治里,病情容易反复,不能根除。打封闭针或服用西药、激素类药物可暂时抑制疼痛,却并不能起到根治作用,而且长期服用会造成药物依赖性和内脏损伤,各种副作用明显增多而造成终身遗憾。现有内服中药大部分作用缓慢,存在反复复发等缺点,如活血舒筋汤等。Rheumatism, rheumatoid arthritis, hyperosteogeny, lumbar disc herniation, frozen shoulder, postpartum wind, sciatica, etc., all belong to the category of wind-cold-damp arthralgia in traditional Chinese medicine. At present, the main methods for treating the above-mentioned diseases include surgical excision, traction, physical therapy, acupuncture, medicine for external use, oral administration of traditional Chinese medicine or sealing injections or taking western medicine hormone drugs and the like. Surgical treatment has the disadvantages of high risk, high cost, poor curative effect, and long postoperative recovery period. Acupuncture and moxibustion has a certain therapeutic effect on mild symptoms, but it is easy to relapse and the therapeutic effect is average. Medicines for external use, such as common patches, can only pull out the poison on the surface of the skin, but they can do nothing to the wind-evil-damp arthralgia that penetrates into the internal organs. Traction and physiotherapy not only have a long treatment cycle, but also only treat the surface but not the interior, so the condition is prone to relapse and cannot be eradicated. Closing injections or taking western medicine and hormone drugs can temporarily suppress the pain, but it cannot cure the pain, and long-term use will cause drug dependence and visceral damage, and various side effects will obviously increase, resulting in lifelong regret. Most of the existing Chinese medicines for oral administration are slow in action and have shortcomings such as repeated recurrences, such as Huoxue Shujin Decoction and the like.
发明内容 Contents of the invention
发明人根据上述疾病的临床症状,结合古代医学精华对风寒湿痹的论述,认为风湿、类风湿性关节炎、腰椎间盘突出、坐骨神经痛等各种病症因长期或偶感风、寒、湿进入经络滞留于内,所以病变出现。发明人以祛风除湿、活血通络为纲,同时以化瘀解毒、和胃健脾、益气止痛、补肝肾、强筋骨为本,使之综合调理、整体得到治疗。According to the clinical symptoms of the above-mentioned diseases, the inventor, in combination with the discussion of wind-cold-damp arthralgia by the essence of ancient medicine, believes that various diseases such as rheumatism, rheumatoid arthritis, lumbar disc herniation, sciatica, etc. are caused by long-term or occasional wind, cold, and dampness entering the meridians. Stuck in the inside, so the disease appears. The inventor takes dispelling wind and removing dampness, promoting blood circulation and dredging collaterals as the key points, and at the same time takes the principles of dispelling blood stasis and detoxification, harmonizing the stomach and invigorating the spleen, replenishing qi and relieving pain, nourishing the liver and kidney, and strengthening bones and muscles, so as to comprehensively regulate and treat the whole body.
本发明的目的是提供一种治疗风湿、类风湿性关节炎、腰椎间盘突出、坐骨神经痛的中药制剂,其治愈率高、治疗范围广、疗效迅速,可除根治本,较好地克服了现有治疗该病药剂所存在的缺陷。The object of the present invention is to provide a kind of Chinese medicine preparation for treating rheumatism, rheumatoid arthritis, lumbar intervertebral disc herniation and sciatica, which has a high cure rate, a wide range of treatment, rapid curative effect, can cure the root cause, and overcomes the existing problems preferably. There are defects in the medicament for the treatment of the disease.
本发明所采取的技术方案是采用以下重量份药物组成:制马钱子 80—100、甘草 20—30、当归 30—50、血竭 30—50、桂枝 30—50、制川乌 30—50、制草乌 30—50、防己 30—50、杜仲 30—50、透骨草 40—60、伸筋草 40—60、藿香 40—60、苍术 40—60、川芎 40—60、三棱 40—60、五灵脂 40—60、三七 40—60、续断 40—60。The technical solution adopted by the present invention is to use the following drug composition in parts by weight: 80-100 parts by weight of Strychnis chinensis, 20-30 parts of Radix Glycyrrhizae, 30-50 parts of Angelica sinensis, 30-50 parts of Dracaena japonicus, 30-50 parts of Guizhi, 30-50 parts of Aconitum japonica 50. Zhicaowu 30-50, Fangji 30-50, Eucommia 30-50, Speranthema 40-60, Shenjincao 40-60, Huoxiang 40-60, Atractylodes 40-60, Chuanxiong 40-60, three Rib 40-60, Wulingzhi 40-60, Panax notoginseng 40-60, Dipsacus 40-60.
制备本发明药物制剂的配方优选重量份配比范围是:制马钱子 85—95、甘草 20—28、当归 35—45、血竭 35—45、桂枝 35—45、制川乌35—45、制草乌 35—45、防己 35—45、杜仲 35—45、透骨草 45—58、伸筋草 45—58、藿香 45—58、苍术 45—58、川芎 45—58、三棱 45—58、五灵脂 45—58、三七 45—58、续断 45—58。构成本发明一种治疗风湿、类风湿性关节炎、腰椎间盘突出、坐骨神经痛的中药制剂。The preferred weight ratio range of the formula for preparing the pharmaceutical preparation of the present invention is: 85-95 parts by weight, 20-28 licorice, 35-45 angelica, 35-45 blood, 35-45 cassia twig, 35-45 45. Zhicaowu 35-45, Fangji 35-45, Eucommia 35-45, Speranthema 45-58, Shenjincao 45-58, Huoxiang 45-58, Atractylodes 45-58, Chuanxiong 45-58, three Rib 45-58, Wulingzhi 45-58, Panax notoginseng 45-58, Dipsacus 45-58. Constitute a Chinese medicine preparation for treating rheumatism, rheumatoid arthritis, lumbar intervertebral disc herniation and sciatica of the present invention.
本发明所述的治疗风湿、类风湿性关节炎、腰椎间盘突出及坐骨神经痛的中药制剂是块剂或散剂或丸剂。The traditional Chinese medicine preparation for treating rheumatism, rheumatoid arthritis, lumbar intervertebral disc herniation and sciatica described in the present invention is block, powder or pill.
将上述各组分制成本发明制剂的生产方法是:取各原料分别进行精选、去杂,按配比重量称取各组分进行粉碎,过80目标准筛,混匀,用制丸机浓缩成水丸,分装成成品即可。The production method of making the above-mentioned components into the preparation of the present invention is as follows: take each raw material and select and remove impurities respectively, weigh each component according to the proportioning weight and pulverize, pass through an 80-mesh standard sieve, mix evenly, and use a pellet machine Concentrate into water pills and pack into finished products.
本发明制剂原料中:以马钱子、川乌、草乌、透骨草、伸筋草为君,具有祛风除湿、散结消肿、通络止痛等功能。痛则不通,通则不痛,透达关节,化凝为散,使神经不受压迫,消除骨刺及髓核自行萎缩,恢复正常功能;以当归、血竭、川芎、三棱、五灵脂、三七为臣,具有活血止痛、化瘀解毒等作用;以续断、杜仲为佐,具有补肝肾、强筋骨等作用;以桂枝、甘草、防己、霍香、苍术为使,具有健脾益气、祛风止痛、和胃化湿、发汗解表、利水消肿等功能。本药配方合理,有祛风除湿、活血通络、化瘀解毒、和胃健脾、益气止痛、发汗解表、利水消肿、补肝肾强筋骨等疗效,具有标本兼治,根除而不复发,治愈率高等显著特点。Among the raw materials of the preparation of the present invention: Nuxychia, Aconitum Aconitum, Aconitum Aconitum, Tugucao, and Shenjincao are the main ones, which have the functions of expelling wind and dampness, dispelling stagnation and swelling, dredging collaterals and relieving pain. Pain leads to blockage, generality means no pain, penetrates the joints, dissolves condensate into powder, prevents nerves from being compressed, eliminates bone spurs and spontaneous atrophy of the nucleus pulposus, and restores normal functions; Radix Notoginseng is a minister, which has the effects of promoting blood circulation and relieving pain, removing blood stasis and detoxification; taking Dipsacus and Eucommia as assistants, it has the effects of nourishing the liver and kidney, strengthening bones and muscles, etc. It has the functions of replenishing qi, dispelling wind and relieving pain, harmonizing stomach and reducing dampness, sweating and relieving the surface, diuresis and swelling. The formula of this medicine is reasonable. It has curative effects such as expelling wind and dehumidification, promoting blood circulation and dredging collaterals, removing blood stasis and detoxification, harmonizing stomach and strengthening spleen, nourishing qi and relieving pain, sweating and relieving exterior syndrome, diuresis and swelling, nourishing liver and kidney and strengthening bones and muscles. Notable features such as recurrence and high cure rate.
具体实施方式: Detailed ways:
取各原料分别进行精选、去杂,按配比重量称取各组分进行粉碎、过80目标准筛,混匀,用制丸机浓缩成水丸,分装成成品。取名“活血追风丸”,每瓶100克,口服每日3次,每次3克,用温开水送下。按疗程服用,每七天为一个疗程。The raw materials are selected and removed respectively, and the components are weighed according to the proportioning weight, crushed, passed through an 80-mesh standard sieve, mixed evenly, concentrated into water pills with a pellet machine, and packaged into finished products. Named "Huoxue Zhuifeng Pill", 100 grams per bottle, orally 3 times a day, 3 grams each time, delivered with warm boiled water. Take according to the course of treatment, every seven days is a course of treatment.
典型病例1:张××,男,现年68岁,内蒙古巴彦淖尔市临河区古城镇前进3组农民,1985年春季就诊,主诉患坐骨神经痛已有13年,两腿及腰部特别疼痛,几乎不能直立行走。Typical case 1: Zhang ××, male, aged 68, a farmer in Group 3, Qianjin, Gucheng Town, Linhe District, Bayannaoer City, Inner Mongolia, went to the doctor in the spring of 1985. He complained of suffering from sciatica for 13 years, with special pain in his legs and waist. Unable to walk upright.
症状:行走困难,腰椎间盘突出压迫坐骨神经引起两腿特别疼痛。Symptoms: Difficulty walking, herniated lumbar disc compresses the sciatic nerve and causes special pain in the legs.
治疗:服本发明药物1疗程,已治愈,上述症状再未出现,现二十多年未复发。Treatment: take medicine of the present invention for 1 course for the treatment of, cured, and above-mentioned symptom does not appear again, and existing more than 20 years do not recur.
典型病例2:李××,女,现年46岁,内蒙古包头市东河区南海子村人。单位:包铁第三建筑工程公司。1997年11月25日就诊。主诉患风湿性关节炎已有数年,久治不愈。Typical case 2: Li ××, female, 46 years old, from Nanhaizi Village, Donghe District, Baotou City, Inner Mongolia. Unit: Baotie Third Construction Engineering Company. On November 25, 1997, he went to see a doctor. The main complaint has been suffering from rheumatoid arthritis for several years, and it has not been cured for a long time.
症状:双腿及双手关节俱痛,行走困难,屈伸不利,尤其天阴下雨、春秋两季则剧痛,并出虚汗,寒湿怕冷,常年穿棉衣。Symptoms: Pain in the joints of both legs and hands, difficulty in walking, difficulty in flexion and extension, especially in cloudy and rainy days, severe pain in spring and autumn, and sweating.
治疗:服本发明药物3个疗程便治愈再未复发。Treatment: take medicine of the present invention for 3 courses for the treatment of and just cure without recurrence.
典型病例3:杨×,男,现年64岁,包头市郊区新城信用社退休职工。主诉患骨质增生压迫坐骨神经痛多年,久治不愈,1999年1月份慕名来我处求治。Typical case 3: Yang ×, male, aged 64, a retired employee of Xincheng Credit Cooperative in the suburbs of Baotou City. Suffering from bone hyperplasia and oppressed sciatica for many years, the chief complained that it could not be cured for a long time. In January 1999, he came to our place for treatment.
症状:腰痛,右腿痛并麻,面色萎黄,精神不振,腰腿发凉。Symptoms: low back pain, right leg pain and numbness, sallow complexion, lack of energy, cold waist and legs.
治疗:服本发明药物3个疗程痊愈,至今已有7年未见复发。Treatment: take medicine of the present invention and recover from illness after 3 courses of treatment, and no recurrence has been seen in 7 years so far.
典型病例4:王××,男,现年33岁,内蒙古巴彦淖尔市临河区八一乡长丰三组人。主诉在部队服役三年,患类风湿性关节炎。曾在北京空军总医院就诊,但只缓解。1995年7月17日来我处就诊,时年22岁。Typical case 4: Wang ××, male, 33 years old, from the third group of Changfeng, Bayi Township, Linhe District, Bayannaoer City, Inner Mongolia. The main complaint was that he had served in the army for three years and suffered from rheumatoid arthritis. Once in the Beijing Air Force General Hospital, but only relief. On July 17, 1995, he came to our office for medical treatment. He was 22 years old at the time.
症状:全身浮肿,各关节疼痛严重,右腿拐,胃口不好,精神萎靡,面色赤红。Symptoms: edema all over the body, severe pain in each joint, crutches in the right leg, poor appetite, listlessness, red complexion.
治疗:服本发明药物42天后全身浮肿已消,关节无痛感,行走正常,胃口好,身体有精神,已痊愈。Treatment: after taking the medicine of the present invention for 42 days, the edema of the whole body has disappeared, and the joints have no pain, and the walking is normal, the appetite is good, and the body is full of energy, and has recovered.
典型病例5:王××,男,现年55岁,内蒙古巴彦淖尔市磴口县公地乡同兴一组。主诉患骨质增生,腰椎间盘突出,坐骨神经痛,起床要半小时,曾到处求治未愈,2005年5月6日来我处就诊。Typical case 5: Wang ××, male, 55 years old, Tongxing Group, Gongdi Township, Dengkou County, Bayannaoer City, Inner Mongolia. Suffering from hyperosteogeny, lumbar intervertebral disc herniation, sciatica, it takes half an hour to get up, and once sought medical treatment everywhere, she came to our place for medical treatment on May 6, 2005.
症状:骨质增生,腰椎间盘突出压迫坐骨神经,两腿疼痛,腰部疼痛严重并弯曲,精神状态差,不能干活。Symptoms: bone hyperplasia, lumbar disc herniation compressing sciatic nerve, pain in both legs, severe waist pain and bending, poor mental state, unable to work.
治疗:服本发明药物5个疗程,可以直立行走,基本不再疼痛,精神状态好,并可以干活,基本痊愈。Treatment: take 5 courses of treatment of medicine of the present invention, can walk upright, no longer pain substantially, mental state is good, and can work, recover from illness substantially.
典型病例6:常××,男,现年59岁,甘肃省定西市岷县茶埠镇茶埠村3组人。主诉患骨质增生,坐骨神经痛,并有II型糖尿病,常年疼痛难忍。2005年9月17日来我处就诊。Typical case 6: Chang ××, male, aged 59, from Group 3, Chabu Village, Chabu Town, Minxian County, Dingxi City, Gansu Province. The main complaint is suffering from hyperosteogeny, sciatica, and type II diabetes, and the pain is unbearable all the year round. On September 17, 2005, he came to our place for medical treatment.
症状:腰部骨质增生压迫坐骨神经痛,左腿疼痛并麻,行走不便。Symptoms: Lumbar bone hyperplasia oppresses sciatica, left leg pain and numbness, difficulty walking.
治疗:服本发明药物2个疗程便行走自如,不再疼痛,精神状态好,已痊愈。Treatment: take medicine of the present invention for 2 courses of treatment and just walk freely, pain no longer, mental state is good, fully recovered.
典型病例7:张××,男,现年74岁,内蒙古巴彦淖尔市临河区双河镇奋斗二组人。主诉患腰椎间盘突出,坐骨神经痛已有十余年。2005年8月11日来我处就诊。Typical case 7: Zhang ××, male, 74 years old, a member of Group 2, Fendou, Shuanghe Town, Linhe District, Bayannur City, Inner Mongolia. Suffering from lumbar intervertebral disc herniation and sciatica for more than ten years. On August 11, 2005, he came to our place for medical treatment.
症状:常年腰痛,右腿痛,行走不便。Symptoms: perennial low back pain, right leg pain, difficulty walking.
治疗:服本发明药物1个疗程,上述症状全部消失,已痊愈。Treatment: take 1 course of treatment of medicine of the present invention, above-mentioned symptom all disappears, fully recovered.
典型病例8:王×,女,25岁,内蒙古巴彦淖尔市临河区东环办人。2006年3月份来我处就诊。主诉患类风湿性关节炎一年多。Typical case 8: Wang ×, female, 25 years old, from the Donghuan Office of Linhe District, Bayannaoer City, Inner Mongolia. In March 2006, he came to our office for medical treatment. Complaints of suffering from rheumatoid arthritis for more than a year.
症状:全身关节疼痛,手腕尤剧并肿,每到阴天下雨春秋两季更甚,2006年2月在我市医院化验,类风湿因子68.3。Symptoms: Joint pains all over the body, especially severe and swollen wrists, especially in spring and autumn when it is cloudy and rainy. In February 2006, it was tested in the hospital of our city, and the rheumatoid factor was 68.3.
治疗:服本发明药物6个疗程,全身关节及手腕基本不再疼痛并不肿,2006年6月份去市医院化验类风湿因子为11,基本恢复正常。Treatment: take the medicine of the present invention for 6 courses of treatment, and the joints and wrists of the whole body are no longer painful and swollen. In June 2006, the rheumatoid factor was 11 in the city hospital, and it was basically back to normal.
本药共治疗患者5557例,总有效率96.7%,治愈率93.5%,显效3.2%。The drug has treated 5557 patients, with a total effective rate of 96.7%, a cure rate of 93.5%, and a marked effect of 3.2%.
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