CN101708324B - Plaster used for treating femoral head necrosis and preparation method thereof - Google Patents
Plaster used for treating femoral head necrosis and preparation method thereof Download PDFInfo
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Abstract
The invention provides plaster used for treating femoral head necrosis and a preparation method thereof. The plaster is prepared from the following raw materials in parts by weight: 5 to 10 parts of safflower, 15 to 30 parts of Chinese angelica, 15 to 30 parts of wine himalayan teasel root, 10 to 20 parts of medicinal cyathula root, 10 to 20 parts of williams elder twig, 15 to 30 parts of danshen root, 15 to 30 parts of malaytea scurfpea fruit, 20 to 40 parts of clematis root, 10 to 30 parts of dried ginger, 5 to 30 parts of dragon's blood, 20 to 40 parts of sanchi, 20 to 40 parts of fortune'sdrynaria rhizome, 10 to 20 parts of ground beetle(Eupolyphaga sinensis Walker), 15 to 30 parts of leech, 5 to 10 parts of prepared nux vomica, and 30 to 60 parts of dog's bone. The medicaments are used together, and have the effects of activating blood and dissipating stasis, nourishing bones and relaxing tendons, dispelling wind and dissipating cold, and tonifying kidney and strengthening bones. The prepared plaster applied to the wounded parts and acted on the parts such as skin, acupuncture points and the like can accelerate blood circulation, increase local skin temperature, obviously improve the transdermal capability of the medicament, enable the medicinal effect of the formulation to directly reach the focus, and play a role in freeing channels and network vessels, enhancing sinews and strengthening bones.
Description
Technical field:
The present invention relates to a kind of plaster for the treatment of the ischemic necrosis of femoral head disease, relate to a kind of plaster that is used for the treatment of femur head necrosis and preparation method thereof specifically.
Background technology:
Femur head necrosis, claim ischemic necrosis of femoral head again, be a kind of, thereby the orthopaedics difficult diseases of the hip arthralgia or knee joint peripheral pain, functional disorder even collapse of the femoral head occurs owing to capital blood supplies of factors disrupt such as alcoholism, hormone, wounds.
Epidemiological study proves that femur head necrosis is the pathological process due to osteocyte, medullary cell and the death of adipose cell isoreactivity composition.In recent years, because wound, drink, hormone abuse is in rising trend, and the sickness rate of femur head necrosis is risen year by year.The epidemic diseases that domestic scholars is carried out China's femur head necrosis shows that for investigation its sickness rate is: Plain peasant 11.76/ ten thousand people, urbanite 9.57/ ten thousand people, workman 7.92/ ten thousand people, hill farmer 6.29/ ten thousand people, coastal fisherman 5.53/ ten thousand people.
Doctor trained in Western medicine generally all adopts the operation method treatment to the treatment of femur head necrosis, and the artificial femoral head replacement has limitation, relatively is fit to the old people, also can only keep about 10 years after changing.But its shortcoming is the surgery cost height, wound is big, limitation is big, and is difficult for being accepted by the patient.Moreover part patient has surgical contraindication and can not adopt operative treatment, and certainly, the course of treatment is not long for doctor trained in Western medicine expectant treatment effect.
The traditional Chinese medical science thinks that femur head necrosis belongs to " rheumatism involving the bone ", " osteomyelitis " category.Human five internal organs's six internal organs, extremity, bones of the body collectively all have meridians to link to each other, by meridians conducts information, conveying QI and blood.The growth of osseous tissue, growth, reparation and normal physiological function thereof are relevant with kidney qi, on the other hand, also relevant with the state of channels in the bone on the one hand.Under the normal condition, bone appoplexy involving the collateral beniol is freely without hindrance, can be in skeleton with QI-blood circulation, growth, growth, the reparation of bone played an important role.If owing to wound or other reason make that passages through which vital energy circulates is obstructed in the bone, the growth of bone, growth, reparation will be affected, and " channels " in the femoral head is not rich, " QI and blood " is seldom few, and easier generation blood supply disorder causes ischemia, necrosis.
Summary of the invention:
The objective of the invention is at above problem, and a kind of plaster that is used for the treatment of femur head necrosis of development and preparation method thereof, it is that channels, promoting flow of QI and blood, invigorating the kidney and strengthening the bones are method of treatment in the bone to dredge, the plaster of selecting for use Chinese herbal medicine to make according to certain technology, the external application affected part reaches the effect for the treatment of both the principal and secondary aspects of a disease.
Technical scheme of the present invention is achieved in that the plaster that is used for the treatment of femur head necrosis, it is that preparation of raw material by the following weight component forms: Flos Carthami 5-10 part, Radix Angelicae Sinensis 15-30 part, prepared RADIX DIPSACI with yellow rice wine 15-30 part, Radix Cyathulae 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Fructus Psoraleae 15-30 part, Radix Clematidis 20-40 part, Rhizoma Zingiberis 10-20 part, Sanguis Draxonis 15-30 part, Radix Notoginseng 20-40 part, Rhizoma Drynariae 20-40 part, Eupolyphaga Seu Steleophaga (eupolyphaga) 10-20 part, Hirudo 15-30 part, Semen Strychni (processed) 5-10 part, Os Canitis 30-60 part.
Technical scheme of the present invention can be achieved in that the plaster that is used for the treatment of femur head necrosis, it is that preparation of raw material by the following weight component forms: Flos Carthami 5-8 part, Radix Angelicae Sinensis 15-20 part, prepared RADIX DIPSACI with yellow rice wine 15-20 part, Radix Cyathulae 10-15 part, Ramulus Sambuci Williamsii 10-15 part, Radix Salviae Miltiorrhizae 15-20 part, Fructus Psoraleae 15-20 part, Radix Clematidis 20-30 part, Rhizoma Zingiberis 10-15 part, Sanguis Draxonis 15-20 part, Radix Notoginseng 20-30 part, Rhizoma Drynariae 20-30 part, Eupolyphaga Seu Steleophaga (eupolyphaga) 10-15 part, Hirudo 15-20 part, Semen Strychni (processed) 5-8 part, Os Canitis 30-40 part.
Technical scheme of the present invention can also be achieved in that the plaster that is used for the treatment of femur head necrosis, and it is that preparation of raw material by the following weight component forms: 10 parts on Flos Carthami, 30 parts of Radix Angelicae Sinensis, 30 parts of prepared RADIX DIPSACI with yellow rice wine, 20 parts of Radix Cyathulaes, 20 parts of Ramulus Sambuci Williamsii, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of Fructus Psoraleaes, 40 parts of Radix Clematidis, 20 parts of Rhizoma Zingiberiss, 30 parts of Sanguis Draxonis, 40 parts of Radix Notoginseng, 40 parts of Rhizoma Drynariae, 20 parts of Eupolyphaga Seu Steleophagas (eupolyphaga), 30 parts of Hirudos, 10 parts of Semen Strychni (processed)s, 60 parts of Os Canitis.
Technical scheme of the present invention can also be achieved in that the preparation method of the plaster that is used for the treatment of femur head necrosis, and it is made by following steps:
The first step, pour Oleum sesami 1-3 liter in iron pan into, the amount of Oleum sesami is as the criterion to flood powder, is heated to when Oleum sesami is little to boil, with Flos Carthami 5-10 part, Radix Angelicae Sinensis 15-30 part, prepared RADIX DIPSACI with yellow rice wine 15-30 part, Radix Cyathulae 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Fructus Psoraleae 15-30 part, Radix Clematidis 20-40 part, Rhizoma Zingiberis 10-20 part, Sanguis Draxonis 15-30 part, Radix Notoginseng 20-40 part, Rhizoma Drynariae 20-40 part, Eupolyphaga Seu Steleophaga (eupolyphaga) 10-20 part, Hirudo 15-30 part, Semen Strychni (processed) 5-10 part, Os Canitis 30-60 part, after choosing clean removal impurity, pour in little Oleum sesami that boils, constantly stir, make the medicine thermally equivalent, fried to withered and yellow or withered when black, filter and remove residue is made as lubricate;
Second step, the amount of press lubricate, 2 parts lubricate is joined 1 part of Plumbum preparatium, and the Plumbum preparatium is placed in the clean iron pan to fry to pellet with slow fire does not have aqueous vapor, loose for spending;
The 3rd step, in iron pan, 2 parts of lubricates are heated with high heat, when lubricate drips into pearl, with lubricate from fire, press the weight ratio of lubricate and Plumbum preparatium then, lubricate: Plumbum preparatium=2: 1, lubricate is put in the Plumbum preparatium, constantly by stirring clockwise, when the oiliness hands of hands, wire drawing is constantly for well with the sticking hands of ointment with the Kuwaki rod, stop to stir, be made as ointment, again ointment is put into cold water, soak, detoxification changes water every day once, can use after seven days;
The 4th step, when using, the ointment of the 3rd step processing is placed container, with water-bath, slow fire, fusing, treat the ointment fusing after, rolled into a ball ointment with bamboo chopsticks, share equally on the byssus of 8cm * 15cm, be the plaster that is used for the treatment of femur head necrosis.
The pharmacological action that side's medicine of the present invention is formed:
Flos Carthami: suffering, temperature.Effect: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.
Radix Angelicae Sinensis: sweet, hot, temperature.Effect: enrich blood and invigorate blood circulation, rheumatic arthralgia, traumatic injury.
Prepared RADIX DIPSACI with yellow rice wine: toil, tepor.Effect: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.
Radix Cyathulae: hardship, acid.Effect: invigorating the liver and kidney, bone and muscle strengthening, continuous folding is hindered.
Ramulus Sambuci Williamsii: sweet, bitter, flat.Effect: reunion of bone, promoting blood circulation and stopping pain, expelling wind and removing dampness.
Radix Salviae Miltiorrhizae: hardship is slightly cold.Invigorate blood circulation and disappear bitterly promoting tissue regeneration by removing blood stasis.
Fructus Psoraleae: can promote bone marrow hematogenesis by regulating nerve and blood system, mend and add muscles and bones.
Radix Clematidis: the hot temperature of loosing is logical, and its property is apt to away, has both dispelled at the wind of table, can change the wetting in the lining again, and stimulating the menstrual flow reaches network, can lead and can declare.
Rhizoma Zingiberis: suffering, heat.Warming spleen and stomach for dispelling cold is the messenger drug detoxifcation, and recuperating depleted YANG is promoted blood circulation, and removing blood stasis removes wind, and the vital organs of the human body are opened in limb joint, logical four sides.
Sanguis Draxonis: the good reputation that " panacea of invigorating blood circulation " arranged.Clots absorbing pain relieving, hemostasis, living thigh.
Radix Notoginseng: the clots absorbing of promoting blood circulation, clots absorbing and sword fresh blood, subduing swelling and relieving pain.
Rhizoma Drynariae: hardship, temperature.Blood circulation promoting and blood stasis dispelling, detumescence are only educated, the continuous muscle of the kidney invigorating.
Eupolyphaga Seu Steleophaga (eupolyphaga): change silt hemostasis, reducing swelling and alleviating pain, collateral dredging reason back, connect the muscle symplectic bone.
Hirudo: removing blood stasis, removing blood stasis stimulates the menstrual flow.Be used for traumatic injury, the card of stagnation of blood stasis.
Semen Strychni (processed): blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.
Os Canitis: sweet in the mouth; Salty; Warm in nature.Wind-expelling pain-stopping, the kidney invigorating.
Plumbum preparatium: external detoxifying and relieving itching, the effect of convergence granulation promoting.It is the raw material of plaster, is boiled into plaster with vegetable oil.
More than all medicines shared, have the effect of blood circulation promoting and blood stasis dispelling, nourishing bone Shujin, expelling wind and cold, invigorating the kidney and strengthening the bones.Stick the affected part after making plaster, with the Chinese medicine drug effect in skin, behind the positions such as acupuncture points on the human body, can accelerate blood circulation, local skin temperature increases, the drug transdermal ability obviously improves, make the prescription efficacy of a drug focus of going directly, give full play to its dredging the meridian, effects such as flourish muscle bone strengthening, make unbalanced yang blood and qi meridians be readjusted and improve, the effect of each strain specific antibodies and non-specific antibody in the enhancing in various degree, netted dermal system functional activity and body, thereby the approach of realization human body immunity improving function, and then the recovery of promotion body function, reach the purpose of curing the disease.
Therapeutic Method of the present invention is: the external application affected part, paste every subsides logotype 7 days per course of treatment 8.
Good effect of the present invention is:
1, the present invention has good effect, and instant effect is easy to use, the characteristics of compatibility safety non-toxic.
2, this formula for a product and preparation technology are simple, and the patent medicine cost is low, are applicable to that rural area, mountain area shortage of medical services and medicines crowd use.
3, the present invention is with pure Chinese medicine processing, the treatment femur head necrosis, and treating both the principal and secondary aspects of a disease, and it is little not have wound, no pain, side effect, need not be in hospital, and expense is low, the cure rate height, relapse rate is low, and the patient is acceptant.
4, effective percentage accounts for 100% to 310 routine patient treatments through clinical for many years in the present invention, cure rate 89%.
The specific embodiment:
The present invention is described in further detail below in conjunction with embodiment:
Embodiment one: be used for the treatment of the plaster of femur head necrosis, it is that preparation of raw material by the following weight component forms: Flos Carthami 10g, Radix Angelicae Sinensis 30g, prepared RADIX DIPSACI with yellow rice wine 30g, Radix Cyathulae 20g, Ramulus Sambuci Williamsii 20g, Radix Salviae Miltiorrhizae 30g, Fructus Psoraleae 30g, Radix Clematidis 40g, Rhizoma Zingiberis 20g, Sanguis Draxonis 30g, Radix Notoginseng 40g, Rhizoma Drynariae 40g, Eupolyphaga Seu Steleophaga (eupolyphaga) 20g, Hirudo 30g, Semen Strychni (processed) 10g, 60 parts of Os Canitis;
Be used for the treatment of the preparation method of the plaster of femur head necrosis, it is made by following steps:
The first step, in iron pan, pour 2 liters of Oleum sesami into, when being heated to little the boiling of oil, with Flos Carthami 10g, Radix Angelicae Sinensis 30g, prepared RADIX DIPSACI with yellow rice wine 30g, Radix Cyathulae 20g, Ramulus Sambuci Williamsii 20g, Radix Salviae Miltiorrhizae 30g, Fructus Psoraleae 30g, Radix Clematidis 40g, Rhizoma Zingiberis 20g, Sanguis Draxonis 30g, Radix Notoginseng 40g, Rhizoma Drynariae 40g, Eupolyphaga Seu Steleophaga (eupolyphaga) 20g, Hirudo 30g, Semen Strychni (processed) 10g, Os Canitis 60g, choose clean removal impurity after, pour in little oil that boils, constantly stir, make the medicine thermally equivalent, fried to withered and yellow or withered when black, filtering residue is made as lubricate;
Second step, the amount of press lubricate are got 500g lubricate and 250g Plumbum preparatium, and earlier the Plumbum preparatium being placed in the clean iron pan to fry to pellet with slow fire does not have aqueous vapor, loose for spending;
The 3rd step, in iron pan, the 500g lubricate is heated with high heat, when lubricate drips into pearl, with lubricate from fire, then putting into lubricate through the 250g Plumbum preparatium of the second step processing, with the Kuwaki rod constantly by stirring clockwise, with the sticking hands of ointment when hands oiliness hands, wire drawing is constantly for well, stop to stir, be made as ointment, put into cold water again, soak, detoxification changes water every day once, can use after seven days;
The 4th step, when using, the ointment of the 3rd step processing is placed container, with water-bath, slow fire, fusing, treat the ointment fusing after, rolled into a ball ointment with bamboo chopsticks, share equally on the byssus of 8cm * 15cm, be the plaster that is used for the treatment of femur head necrosis.
Clinical typical treatment case:
Treatment case 1:
The patient, Sun Hongyan, the woman, 26 years old, Gong Dianxiang Lou Ma people from village, Ye County, the fl head causes femur head necrosis because of suffering from bone tuberculosis.1 year medical history, X-ray shows the left side collapse of the femoral head, slight flat, left side femoral head edge blurry, the outer outward turning in the wrong of protracting is limited, the hip arthralgia, walking disorder.In in October, 2008 the court treatment, one course of treatment of medication, the hip arthralgia disappears substantially, X-ray shows that femoral head has blood flow to increase, two courses of treatment of medication, pain disappears, and X-ray shows that femoral head finishes substantially, the periosteum growth, three courses of treatment, the same with the normal person, X-ray shows that the femoral head growth of subsiding is normal, the bone tuberculosis factor disappears, and is basic complete.
Treatment case 2:
Patient: Dang Xiaorong, woman, 16 years old, people from town pacifies the good in the Jiaxian County, patient's unknown cause, two lower limbs just can not be walked at that time, were no mattress both sides femur head necrosis through how tame hospital diagnosis, treatment through the multidigit doctor, do not have good effect, the X-ray sheet shows the bilateral femoral head necrosis to mid-term, and movable walking needs to use crutches, need constantly take the analgesic symptom that eases the pain every day, through accepting the symptomatic treatment of my institute, one the course of treatment pain symptom obviously alleviate, walking not, reuse turns, function of joint and movable amplitude are obviously improved, continuous use treated for two and half courses of treatment, and pain symptom disappears, and X-ray shows the basic rehabilitation of femoral head, the same with the normal person, can go to school on class.
Treatment case 3:
Patient: Seedling profit retention, man, 49 years old, Shen Hou people from town, Yuzhou City, directly fracturing because of femur makes femur head necrosis, and operation is after how tame hospitalize, be of no curative effect, ease the pain, be unable to leave the bed by taking medicine, life is not able to support oneself, in in March, 2009 the court treatment, X-ray shows that the femur footpath is downright bad, one course of treatment of medication, the hip arthralgia obviously alleviates, and X-ray shows that downright bad position blood flow increases.Two courses of treatment of medication, pain disappears substantially, and X-ray shows that location of necrosis recovers normally substantially, and reuse pain half course of treatment disappears, and heals entirely in the osteonecrosis position, and the patient lives and is able to support oneself, and walking can be freely.
Claims (4)
1. plaster that is used for the treatment of femur head necrosis is characterized in that: it is that preparation of raw material by the following weight component forms: Flos Carthami 5-10 part, Radix Angelicae Sinensis 15-30 part, prepared RADIX DIPSACI with yellow rice wine 15-30 part, Radix Cyathulae 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Fructus Psoraleae 15-30 part, Radix Clematidis 20-40 part, Rhizoma Zingiberis 10-20 part, Sanguis Draxonis 15-30 part, Radix Notoginseng 20-40 part, Rhizoma Drynariae 20-40 part, Eupolyphaga Seu Steleophaga 10-20 part, Hirudo 15-30 part, Semen Strychni (processed) 5-10 part, Os Canitis 30-60 part.
2. the plaster that is used for the treatment of femur head necrosis according to claim 1 is characterized in that: it is that preparation of raw material by the following weight component forms: Flos Carthami 5-8 part, Radix Angelicae Sinensis 15-20 part, prepared RADIX DIPSACI with yellow rice wine 15-20 part, Radix Cyathulae 10-15 part, Ramulus Sambuci Williamsii 10-15 part, Radix Salviae Miltiorrhizae 15-20 part, Fructus Psoraleae 15-20 part, Radix Clematidis 20-30 part, Rhizoma Zingiberis 10-15 part, Sanguis Draxonis 15-20 part, Radix Notoginseng 20-30 part, Rhizoma Drynariae 20-30 part, Eupolyphaga Seu Steleophaga 10-15 part, Hirudo 15-20 part, Semen Strychni (processed) 5-8 part, Os Canitis 30-40 part.
3. the plaster that is used for the treatment of femur head necrosis according to claim 1 is characterized in that: it is that preparation of raw material by the following weight component forms: 10 parts on Flos Carthami, 30 parts of Radix Angelicae Sinensis, 30 parts of prepared RADIX DIPSACI with yellow rice wine, 20 parts of Radix Cyathulaes, 20 parts of Ramulus Sambuci Williamsii, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of Fructus Psoraleaes, 40 parts of Radix Clematidis, 20 parts of Rhizoma Zingiberiss, 30 parts of Sanguis Draxonis, 40 parts of Radix Notoginseng, 40 parts of Rhizoma Drynariae, 20 parts of Eupolyphaga Seu Steleophagas, 30 parts of Hirudos, 10 parts of Semen Strychni (processed)s, 60 parts of Os Canitis.
4. one kind prepares the method that is used for the treatment of the plaster of femur head necrosis as claimed in claim 1, it is characterized in that it may further comprise the steps:
The first step, pour Oleum sesami 1-3 liter in iron pan into, the amount of Oleum sesami is as the criterion to flood powder, is heated to when Oleum sesami is little to boil, with Flos Carthami 5-10 part, Radix Angelicae Sinensis 15-30 part, prepared RADIX DIPSACI with yellow rice wine 15-30 part, Radix Cyathulae 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Fructus Psoraleae 15-30 part, Radix Clematidis 20-40 part, Rhizoma Zingiberis 10-20 part, Sanguis Draxonis 15-30 part, Radix Notoginseng 20-40 part, Rhizoma Drynariae 20-40 part, Eupolyphaga Seu Steleophaga 10-20 part, Hirudo 15-30 part, Semen Strychni (processed) 5-10 part, Os Canitis 30-60 part, after choosing clean removal impurity, pour in little Oleum sesami that boils, constantly stir, make the medicine thermally equivalent, fried to withered and yellow or withered when black, filter and remove residue is made as lubricate;
Second step, the amount of press lubricate, 2 parts lubricate is joined 1 part of Plumbum preparatium, and the Plumbum preparatium is placed in the clean iron pan to fry to pellet with slow fire does not have aqueous vapor, loose for spending;
The 3rd step, in iron pan, 2 parts of lubricates are heated with high heat, when lubricate drips into pearl, with lubricate from fire, press the weight ratio of lubricate and Plumbum preparatium then, lubricate: Plumbum preparatium=2: 1, lubricate is put in the Plumbum preparatium, constantly by stirring clockwise, when the oiliness hands of hands, wire drawing is constantly for well with the sticking hands of ointment with the Kuwaki rod, stop to stir, be made as ointment, again ointment is put into cold water, soak, detoxification changes water every day once, can use after seven days;
The 4th step, when using, the ointment of the 3rd step processing is placed container, with water-bath, slow fire, fusing, treat the ointment fusing after, rolled into a ball ointment with bamboo chopsticks, share equally on the byssus of 8cm * 15cm, be the plaster that is used for the treatment of femur head necrosis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009102275703A CN101708324B (en) | 2009-12-22 | 2009-12-22 | Plaster used for treating femoral head necrosis and preparation method thereof |
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| CN2009102275703A CN101708324B (en) | 2009-12-22 | 2009-12-22 | Plaster used for treating femoral head necrosis and preparation method thereof |
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| CN101904922B (en) * | 2010-07-28 | 2011-08-31 | 郭海勇 | Plaster for treating pain caused by femoral head necrosis |
| CN105031540A (en) * | 2015-08-24 | 2015-11-11 | 王义朋 | Traditional Chinese medicine for treating ischemic femoral head necrosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101264201A (en) * | 2008-04-23 | 2008-09-17 | 蓝世隆 | Chinese medicinal ointment for treating femoral head necrosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264201A (en) * | 2008-04-23 | 2008-09-17 | 蓝世隆 | Chinese medicinal ointment for treating femoral head necrosis |
Non-Patent Citations (2)
| Title |
|---|
| 任金瑞.股骨头缺血性坏死的中医治疗近况.《河北中医》.1995,第17卷(第2期),43-45. * |
| 刘维立,赵文海,王丹彤.股骨头缺血性坏死治疗常用中药及用药规律.《吉林中医药》.2007,第27卷(第9期),53-54. * |
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