CN102600256B - Traditional Chinese medical composition for treatment of traumatic injury - Google Patents
Traditional Chinese medical composition for treatment of traumatic injury Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medical composition for treatment of traumatic injury, which is prepared with raw materials of the following weight ratio: 20 parts of rheum officinale, 18 parts of lycopodium clavatum, 18 parts of notopterygium roots, 15 parts of eucommia ulmoides, 15 parts of catecholamine, 12 parts of ligusticum wallichii, 12 parts of safflower, 10 parts of pangolin., 10 parts of natural copper, 9 parts of red-rooted salvia, 9 parts of olibanum, 8 parts of myrrh, 6 parts of keel, 5 parts of hematoxylon, 5 parts of teasel roots, 3 parts of drynaria rhizome, 3 parts of honeysuckle and 3 parts of prepared radix aconite. The traditional Chinese medical composition can be used for complete treatment of the traumatic injury, has no toxic, harmful or side effects on the human body and can be prepared easily, and the cost is low. Thus the composition has broad application prospects.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of traumatic injury and preparation method thereof.
Background technology
Traumatic injury general reference injury, also all wounds of name, injury from falling down belong to the commonly encountered diseases in a kind of daily life.People run into beyond thought various wound through regular meeting, as wound, get injured by a fall in life and work, and the lighter injures epidermis, articular sprain and causes that stasis of blood resistance swells and ache, and the weight person disability that disables of fracturing causes serious burden.
Traumatic injury is the bone injury disease of the traditional Chinese medical science, mainly comprises diseases such as infection of bone behind delayed union of fracture, the internal fixation of fracture, soft tissue injury and joint dislocation, and to belong to passages through which vital energy circulates injured more, and QI and blood is impaired, hemorrhage, and the stasis of blood is long-pending does not loose the disease of swelling pain.All have in the stagnant blood stay, blood stasis is stagnated, passages through which vital energy circulates is obstructed or operation is not smooth.Blood stasis does not go, and fresh blood is not given birth to, and newborn fresh blood can not to pacify row in good health, eventually must absurd row and cause change disease multiterminal.Its main pathology is that congestion stop up to stagnate, and the blood resistance of holding one's breath is so serve as mainly to show with pain, swelling.The suitable circulation of qi promoting for the treatment of, dissipating blood stasis is invigorated blood circulation, pain relieving, Shujin, hard bone are main.After right patient's traumatic injury, all with oil preparation for promoting blood circulation by the person of rubbing, hemorrhage aggravation, pain, swelling are more acute, damage is to dark; Oral anti-inflammation analgesic is serious to gastric injury, and particularly patients with gastric disease can not tolerate; Transfusion is easily irritated, the expense height, and the patient suffering uses inconveniently, and all there is defective in Western medicine aspect safety and the dependency, side effect is also relatively large, forms addiction, drug resistance easily, so should not take for a long time.
Motherland's medical science is aspect the treatment traumatic injury disease its unique curative effect being arranged, according to " harmony between man and nature, integration of edible and medicinal herbs in the philosophic thinking and Chinese medicine of the materialistic dialectics; Dialectical executing controlled, treating both the principal and secondary aspects of a disease, inside and outside rule together; Muscles and bones is laid equal stress on, and is association of activity and inertia; Liver governing tendons, kidney governing bones, invigorating the liver and kidney, bone and muscle strengthening; The meridian dredging, damp eliminating numbness, Shujin arteries and veins, detumescence pain, sharp joint; The stagnation of QI then blood stasis, the capable then blood of gas is capable; Stagnation of QI and blood may bring about pain, general rule are not bitterly; Middle disease is namely ended ", act on cooperative compensating between the Chinese medicine ingredients, play the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, reunion of bone altogether.
The Chinese medicine that exist to be used for traumatic injury in the prior art, comprising Chinese medicine for oral administration is arranged, but only its curative effect for oral administration is very undesirable; In addition, also have some varnishs of external or plaster etc., also have some such or such problems, can have side effects to human body after the use that has, as erythra etc.; Also have for oral administration and external uses that combine, this class medicine exists use than the weak point of complexity.Therefore, the new Chinese medicine of researching and developing a kind of high-efficiency low-toxicity, treating both the principal and secondary aspects of a disease is the technical barrier that is still this area.
Summary of the invention
The objective of the invention is in order to overcome disadvantages of background technology, and a kind of easy to use, cheap, the treating both the principal and secondary aspects of a disease that provides, the short Chinese medicine composition composition formula for the treatment of cycle.The present application people in conjunction with secret prescription handed down in the family from generation to generation according to forefathers' experience and oneself medical practice for many years, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways collect the length of many families, based on external treatment with Chinese medicine, seek therapeutic regimen, adopt the natural Chinese medicines raw material, be mixed with treatment traumatic injury Chinese medicine composition of the present invention meticulously in conjunction with traditional lunar physics technique, its compound method is simple, traumatic injury is had the effect of healing.
For achieving the above object, the technical solution used in the present invention is as follows:
A kind of Chinese medicine composition for the treatment of traumatic injury, it is got than feedstock production by following weight,
Radix Et Rhizoma Rhei 20-30 part, Herba Lycopodii 15-20 part, Rhizoma Et Radix Notopterygii 15-20 part, Cortex Eucommiae 15-20 part
Catechu 15-20 part, Rhizoma Chuanxiong 10-15 part, Flos Carthami 10-15 part, Squama Manis 10-15 part
Pyritum 10-12 part, Radix Salviae Miltiorrhizae 8-10 part, Olibanum 8-10 part, Myrrha 8-10 part
Os Draconis 5-10 part, Lignum Sappan 5-10 part, Radix Dipsaci 5-10 part, Rhizoma Drynariae 3-5 part,
Flos Lonicerae 3-5 part, Radix Aconiti Preparata 3-5 part.
The Chinese medicine composition of described treatment traumatic injury is characterized in that the weight portion of its constitutive material is preferably:
20 parts of Radix Et Rhizoma Rhei, 18 parts of Herba Lycopodiis, 18 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Cortexs Eucommiae
15 parts in catechu, 12 parts of Rhizoma Chuanxiongs, 12 parts on Flos Carthami, 10 parts of Squama Maniss
10 parts of Pyritums, 9 parts of Radix Salviae Miltiorrhizaes, 9 parts of Olibanums, 8 parts of Myrrhas
6 parts of Os Draconis, 5 parts of Lignum Sappans, 5 parts of Radix Dipsacis, 3 parts of Rhizoma Drynariae,
3 parts of Flos Loniceraes, 3 parts of Radix Aconiti Preparatas.
Pharmaceutical composition its preparation method of the present invention is: according to the raw material mass mixture ratio weighting raw materials, make powder according to a conventional method respectively, it is stand-by to cross 80 mesh sieves, and whole medicated powder are evenly mixed, and mixes and puts into the wide-mouth vial, standby, namely become the present invention and treat traumatic injury Chinese medicine composition medicinal powder, each 10 grams are taken after mixing it with water with yellow wine, every day 3 times, a course for the treatment of two Mondays.
Prescription characteristics of the present invention: act on cooperative compensating between the Chinese medicine, play the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, reunion of bone altogether., muscles and bones smooth through ruton, QI and blood supplemented nutrition, promoted growth of spur, accelerating union of bone fracture has significant curative effect to the treatment bone does not connect, through the auxiliary treatment fracture, can shorten healing time, can prevent bone does not connect again.Chinese medicine composition composition of the present invention can be divided into two classes, and a class is blood circulation promoting and blood stasis dispelling, dispersing swelling and dissipating binds, to remove pathogen; Another kind of is invigorating the liver and kidney, benefiting essence-blood, nourish the effect that the space between skin and muscles Xingqi is moistened, so make behind delayed union of fracture, the internal fixation of fracture infection of bone, soft tissue injury and joint dislocation disease QI and blood is unobstructed, swelling can disappear, pain must be separated, its muscles and bones, restore funcitons by force.
Function cures mainly: removing toxic substances and promoting subsidence of swelling, pain relieving granulation promoting.Treat various traumatic injury extremely red swelling of the skin, fracture, sprain.
Points for attention: 1., the more serious patient of damage comprises fracture, dislocation and open injury patient, should under physician guidance, use or symptomatic treatment in hospital;
2., damage location is at lower limb, should lie up;
3., hot things such as fasting beef, the flesh of fish, wine and Fructus Capsici Rhizoma Zingiberis Recens Bulbus Allii.
Advantage of the present invention:
This product is stasis-dispelling and pain-killing fast, and congestive edema disappears gradually and takes off, and can walk about three to five days;
The medicinal cost of raw material is low, and existing good economic benefit can alleviate patient's financial burden again, and prescription is reasonable in order, and drug effect is deeply lasting, medicine letter and power is special;
By the choose reasonable to medicine components, proportioning, obtained desirable therapeutic effect, both met state-promulgated pharmacopoeia to the requirement of relevant drug dose, can guarantee excellent curative, non-evident effect again.
The specific embodiment
Embodiment 1
A kind of Chinese medicine composition for the treatment of traumatic injury, it is got than feedstock production by following weight,
20 parts of Radix Et Rhizoma Rhei, 18 parts of Herba Lycopodiis, 18 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Cortexs Eucommiae
15 parts in catechu, 12 parts of Rhizoma Chuanxiongs, 12 parts on Flos Carthami, 10 parts of Squama Maniss
10 parts of Pyritums, 9 parts of Radix Salviae Miltiorrhizaes, 9 parts of Olibanums, 8 parts of Myrrhas
6 parts of Os Draconis, 5 parts of Lignum Sappans, 5 parts of Radix Dipsacis, 3 parts of Rhizoma Drynariae,
3 parts of Flos Loniceraes, 3 parts of Radix Aconiti Preparatas.
Pharmaceutical composition its preparation method of the present invention is: according to the raw material mass mixture ratio weighting raw materials, make powder according to a conventional method respectively, it is stand-by to cross 80 mesh sieves, and whole medicated powder are evenly mixed, and mixes and puts into the wide-mouth vial, standby, namely become the Chinese medicine composition medicinal powder that the present invention treats traumatic injury, each 10 grams are taken after mixing it with water with yellow wine, every day 3 times, a course for the treatment of two Mondays.
Drug action:
The analgesic test
Hot plate causes the pain method and gets 20 of 18-20g kunming mices, places constant temperature [(55 ± 0.5) ℃] water-bath.Measure the threshold of pain on the hot plate, the screening threshold of pain is 20 of 10～30s mices, divides 2 groups at random, and blank group is irritated stomach and given normal saline (0.1g) and medicine group gastric infusion of the present invention (0.1g).0.5h behind the medicine, 1h, 2h survey the threshold of pain respectively, and the result shows that the present invention has significant analgesic activity;
Table 1 medicine of the present invention causes the influence of pain to the mice hot plate
Compare with the blank group,
*P＜0.05
Turn round the body experiment:
20 of kunming mices, be divided into 2 groups at random, be administered once every day, blank group is irritated stomach and is given normal saline (0.1g) and medicine group gastric infusion of the present invention (0.1g), gastric infusion is 5 days continuously, and behind last gastric infusion 1h, lumbar injection 0.6% glacial acetic acid 0.2ml/ only, observe mouse writhing number of times in the 20min, can find that medicine of the present invention turns round the body frequency to the glacial acetic acid induced mice and obviously reduce.
Table 2 medicine of the present invention is to the influence of mouse writhing number of times
| Group | Mice number (only) | Turn round body number of times (20min) |
| Blank group | 10 | 30.25±4.73 |
| Medicine group of the present invention | 10 | 10.71±3.42 |
Embodiment 2
1. clinical data
Selection 135 examples from fracture and soft tissue injury case were gone to a doctor by my institute in recent years are divided into treatment group and matched group at random, and medical history, the state of an illness, age, sex are suitable as far as possible in two groups of cases of selecting for use, and are hospitalization.68 examples are organized in treatment, age 15-57 year, 39 years old mean age.33 examples of wherein fracturing, soft tissue injury 35 examples.Matched group 67 examples, age 17-61 year, 41 years old mean age, 34 examples of wherein fracturing, soft tissue injury 33 examples.
The treatment group is taken treatment traumatic injury Chinese medicine composition of the present invention, and each 10 grams are taken after mixing it with water every day 3 times, a course for the treatment of two Mondays with yellow wine.Matched group adopts the ZHONGHUA DIEDA WAN conventional therapy, each ball, and twice, two week of every day is a course for the treatment of, observes therapeutic effect at any time, affected part swelling regression time was taken the photograph sheet once in per 7 days, checked para-position and growth of spur situation and trouble limb functional rehabilitation time.
Criterion of therapeutical effect: be divided into healing, improvement, invalid three grades
Curative effect of fracture criterion, cure: fracture is satisfied to the line para-position, and the seriality callus formation is arranged, and the broken ends of fractured bone does not have tenderness, does not have the pain of impact, functional rehabilitation.Take a turn for the better: para-position and to line still can, or the fracture para-position is not good, but functional rehabilitation is fair.Invalid: nonunion becomes local obviously deformity, dysfunction.
Soft tissue injury curative effect judging standard: cure: pain, swelling, ecchymosis disappear, and functional rehabilitation is normal.Take a turn for the better: pain, swelling disappear, and function is obviously improved, but affected part still has discomfort.Invalid: symptom, function sign all do not have improvement.
Therapeutic outcome:
In 2 weeks of fracture patient medication, visible callus accounts for 85% under the X line, and in 4 weeks of medication, visible callus accounts for 95% under the X line, and than general conventional therapy that need not Chinese medicine composition of the present invention, 1 times in advance of corresponding treatment time appears in callus.
Simple soft tissue falls, beat, sprain that to begin to functional rehabilitation from medication be administration time.Average administration time is 5-7 days, detumescence fully, no pain.Than general conventional therapy that need not Chinese medicine composition of the present invention, functional rehabilitation, produce effects needs 2-4 week, and the time shifts to an earlier date 3-4 doubly.
Two groups of therapeutic outcomes (P＜0.01) as follows:
| Group | Example is inferior | Cure | Take a turn for the better | Invalid | Total effective rate |
| The treatment group | 68 | 51 | 14 | 3 | 95.6％ |
| Matched group | 67 | 38 | 21 | 8 | 88.1％ |
Two groups obvious effective rate is respectively 95.6% and 88.1%, and significant difference is arranged.
Embodiment 3
Exemplary embodiments
Liu: the woman, 35 years old, the main suit fell down before 1 day accidentally, after namely see right knee joint swelling, pain, can not stretch in the wrongly, swell and ache and can not walk.Do not accept any treatment before the prescription on individual diagnosis.Check when being admitted to hospital: the obvious swelling of right knee joint, right knee joint Zhou Jing is 42cm, left knee joint is 38cm, visible several pieces atropurpureus ecchymosis of right knee joint peripheral, the about 20 * 10cm of area
2, tenderness is obvious around the patella, and knee joint is bent and stretched obstacle.Take the pharmaceutical composition of embodiment 1 preparation, every day 3 times, each 10 grams are taken after mixing it with water with yellow wine.Add tuck circle and LLS of rubber and be fixed in knee-expanding position, ecchymosis obviously goes down around the right knee joint when the 5th day checks, pain disappears substantially, and swelling is obviously disappeared.Right knee joint Zhou Jing reduces to 38cm, through continuing medication and fixing 2 courses for the treatment of and fully recover.
Pay certain, male, 51 years old.The patient slides from stair the morning because of carelessness, and right shoulder pain is stiff at once, checks BP:15/9KPa (110/70mmHg) when being admitted to hospital, the right shoulder drops of patient, and upper body tilts to the right, the left hand holding right hand, face dolorosa.The obvious swelling in right front breast top.X-ray film shows: right clavicle stage casing fracture, the broken ends of fractured bone separates, middle visible 2 comminuted bone cipses.At first adopt traditional Chinese medical science bone-setting manipulation, it is resetted, anti-8 words of binder are fixing outward.Take the pharmaceutical composition of embodiment 1 preparation, every day 3 times, each 10 grams, yellow wine 5ml is oral.Fixing except the solution after 4 weeks, begin to take exercise the shoulder joint activity.X-ray film shows: the fracture site para-position is good, and it is continuous that callus is fusiformis, and fracture line mays be seen indistinctly.Continue to take and take the photograph the X-ray sheet after two courses for the treatment of and show: fracture line is fuzzy, and it is continuous that external callus is fusiformis, consistent in density, and by fracture line, reach the clinical healing standard.
Above-mentioned each Chinese medicine that the present invention adopts is made compatibility mutually, can bring into play its collaborative effect of curing the disease, have drug effect between each composition of used raw material of Chinese medicine and be interweaved and mutually promote and coordinate usefulness, through clinical verification, traumatic injury is had the effect of healing, can relaxing muscles and tendons and activating QI and blood in the collateral, promoting tissue regeneration by removing blood stasis, hemostasis and pain-relieving, in the applicant's medical practice for many years, the case number of healing is numerous, all obtains good effect, and with low cost, alleviate patient's burden.
It is with low cost, evident in efficacy that the application is used for the treatment of the Chinese medicine composition of traumatic injury, has broad application prospects.
Claims (2)
1. a Chinese medicine composition that is used for traumatic injury is characterized in that it is got by following weight proportioning feedstock production,
20 parts of Radix Et Rhizoma Rhei, 18 parts of Herba Lycopodiis, 18 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Cortexs Eucommiae
15 parts in catechu, 12 parts of Rhizoma Chuanxiongs, 12 parts on Flos Carthami, 10 parts of Squama Maniss
10 parts of Pyritums, 9 parts of Radix Salviae Miltiorrhizaes, 9 parts of Olibanums, 8 parts of Myrrhas
6 parts of Os Draconis, 5 parts of Lignum Sappans, 5 parts of Radix Dipsacis, 3 parts of Rhizoma Drynariae,
3 parts of Flos Loniceraes, 3 parts of Radix Aconiti Preparatas.
2. the described Chinese medicine composition of claim 1 is preparing the purposes for the treatment of in the traumatic injury medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101021788A CN102600256B (en) | 2012-04-09 | 2012-04-09 | Traditional Chinese medical composition for treatment of traumatic injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101021788A CN102600256B (en) | 2012-04-09 | 2012-04-09 | Traditional Chinese medical composition for treatment of traumatic injury |
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| Publication Number | Publication Date |
|---|---|
| CN102600256A CN102600256A (en) | 2012-07-25 |
| CN102600256B true CN102600256B (en) | 2013-07-17 |
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| CN105477208A (en) * | 2016-01-14 | 2016-04-13 | 田均庆 | Traditional Chinese medicine composition for mainly treating gonarthromeningitis and preparation method thereof |
| CN106983809A (en) * | 2016-01-21 | 2017-07-28 | 樊桦 | Traumatic injury external application miraculous cure |
| CN107441208A (en) * | 2017-09-13 | 2017-12-08 | 皖南医学院 | A kind of particle for treating traumatic injury and preparation method thereof |
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| CN1246362A (en) * | 1999-07-16 | 2000-03-08 | 田纯成 | Medicine for treating hyperosteogeny |
| CN1650941A (en) * | 2004-11-10 | 2005-08-10 | 姚学艳 | Plaster for treating knocks and falls, and osteopathia |
| CN101524450A (en) * | 2009-04-13 | 2009-09-09 | 王宝岭 | Oral traditional Chinese medicine for setting bones and relieving rigidity of muscles and preparation method thereof |
| CN101612279A (en) * | 2009-07-31 | 2009-12-30 | 徐先启 | A kind of Chinese medicine preparation that promotes union of fracture |
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| KR20050050291A (en) * | 2003-11-25 | 2005-05-31 | 이광현 | A herb remedy |
| WO2008112561A1 (en) * | 2007-03-09 | 2008-09-18 | Pfantastic Medical Research Institute, Llc | Combination therapy for alleviating pain-related conditions |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1246362A (en) * | 1999-07-16 | 2000-03-08 | 田纯成 | Medicine for treating hyperosteogeny |
| CN1650941A (en) * | 2004-11-10 | 2005-08-10 | 姚学艳 | Plaster for treating knocks and falls, and osteopathia |
| CN101524450A (en) * | 2009-04-13 | 2009-09-09 | 王宝岭 | Oral traditional Chinese medicine for setting bones and relieving rigidity of muscles and preparation method thereof |
| CN101612279A (en) * | 2009-07-31 | 2009-12-30 | 徐先启 | A kind of Chinese medicine preparation that promotes union of fracture |
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