CN1582330A - 体外微器官及其相关用途 - Google Patents

体外微器官及其相关用途 Download PDF

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Publication number
CN1582330A
CN1582330A CNA018239064A CN01823906A CN1582330A CN 1582330 A CN1582330 A CN 1582330A CN A018239064 A CNA018239064 A CN A018239064A CN 01823906 A CN01823906 A CN 01823906A CN 1582330 A CN1582330 A CN 1582330A
Authority
CN
China
Prior art keywords
micro
organs
explant
cell
organ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA018239064A
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English (en)
Chinese (zh)
Inventor
E·N·米特拉尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Priority claimed from PCT/IL2001/000976 external-priority patent/WO2003035851A1/fr
Publication of CN1582330A publication Critical patent/CN1582330A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA018239064A 2001-10-23 2001-10-23 体外微器官及其相关用途 Pending CN1582330A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2001/000976 WO2003035851A1 (fr) 2001-10-23 2001-10-23 Micro-organes in vitro, et utilisations correspondantes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2010105147771A Division CN102010851A (zh) 2001-10-23 2001-10-23 体外微器官及其相关用途

Publications (1)

Publication Number Publication Date
CN1582330A true CN1582330A (zh) 2005-02-16

Family

ID=32676735

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA018239064A Pending CN1582330A (zh) 2001-10-23 2001-10-23 体外微器官及其相关用途

Country Status (5)

Country Link
JP (1) JP2005506084A (fr)
KR (2) KR100970195B1 (fr)
CN (1) CN1582330A (fr)
CA (1) CA2464460A1 (fr)
IL (1) IL161472A0 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101743472B (zh) * 2007-05-18 2014-09-17 生命线科学公司 检测器官系统干扰的离体方法
CN104411318A (zh) * 2011-12-23 2015-03-11 人类起源公司 包含脱细胞并再群体化的胎盘血管支架的类器官
CN105334196A (zh) * 2015-09-24 2016-02-17 华东师范大学 一种检测3D类器官中P-gp介导的Rh123转运的方法及应用
CN109082402A (zh) * 2018-08-06 2018-12-25 复旦大学 一种aav-dj型腺相关病毒体外高效感染类器官的用途
CN113774018A (zh) * 2021-08-30 2021-12-10 吉林大学 一种大鼠心肌细胞和心肌成纤维细胞分离和培养的方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501396B2 (en) 2001-11-05 2013-08-06 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
US7468242B2 (en) 2001-11-05 2008-12-23 Medgenics, Inc. Dermal micro organs, methods and apparatuses for producing and using the same
EP2377403A1 (fr) 2003-05-01 2011-10-19 Medgenics, Inc. Micro-organe dermique génétiquement modifié exprimant le facteur VIII
KR101449587B1 (ko) 2006-09-14 2014-10-10 메드제닉스 메디칼 이스라엘 리미티드 장기 지속형 약물 제형
US8454948B2 (en) 2006-09-14 2013-06-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
JP2013532152A (ja) * 2010-06-15 2013-08-15 メドジェニクス・メディカル・イスラエル・リミテッド 長期持続性の医薬製剤
US9951313B2 (en) * 2011-06-02 2018-04-24 President And Fellows Of Harvard College Methods and uses for ex vivo tissue culture systems
RU2631005C1 (ru) * 2016-10-06 2017-09-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет им. Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) Способ культивирования клеток слюнной железы человека

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101743472B (zh) * 2007-05-18 2014-09-17 生命线科学公司 检测器官系统干扰的离体方法
CN104411318A (zh) * 2011-12-23 2015-03-11 人类起源公司 包含脱细胞并再群体化的胎盘血管支架的类器官
CN105334196A (zh) * 2015-09-24 2016-02-17 华东师范大学 一种检测3D类器官中P-gp介导的Rh123转运的方法及应用
CN109082402A (zh) * 2018-08-06 2018-12-25 复旦大学 一种aav-dj型腺相关病毒体外高效感染类器官的用途
CN109082402B (zh) * 2018-08-06 2021-08-17 复旦大学 一种aav-dj型腺相关病毒体外高效感染类器官的用途
CN113774018A (zh) * 2021-08-30 2021-12-10 吉林大学 一种大鼠心肌细胞和心肌成纤维细胞分离和培养的方法
CN113774018B (zh) * 2021-08-30 2023-09-05 吉林大学 一种大鼠心肌细胞和心肌成纤维细胞分离和培养的方法

Also Published As

Publication number Publication date
KR100970195B1 (ko) 2010-07-14
KR20040070343A (ko) 2004-08-07
IL161472A0 (en) 2004-09-27
CA2464460A1 (fr) 2003-05-01
KR20090060381A (ko) 2009-06-11
JP2005506084A (ja) 2005-03-03

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Open date: 20050216