CN1533271A - 在光化疗法中作为光敏化剂的5-氨基乙酰丙酸及其酯与另一光敏剂的组合,以及它们在治疗创伤中的用途 - Google Patents

在光化疗法中作为光敏化剂的5-氨基乙酰丙酸及其酯与另一光敏剂的组合,以及它们在治疗创伤中的用途 Download PDF

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Publication number
CN1533271A
CN1533271A CNA028145801A CN02814580A CN1533271A CN 1533271 A CN1533271 A CN 1533271A CN A028145801 A CNA028145801 A CN A028145801A CN 02814580 A CN02814580 A CN 02814580A CN 1533271 A CN1533271 A CN 1533271A
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CN
China
Prior art keywords
ala
photosensitizer
ester
ala ester
wounds
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Pending
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CNA028145801A
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English (en)
Chinese (zh)
Inventor
J
J·克莱威尼斯
V·汉森
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Photocure ASA
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Photocure ASA
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Publication of CN1533271A publication Critical patent/CN1533271A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA028145801A 2001-07-26 2002-07-25 在光化疗法中作为光敏化剂的5-氨基乙酰丙酸及其酯与另一光敏剂的组合,以及它们在治疗创伤中的用途 Pending CN1533271A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0118251.8A GB0118251D0 (en) 2001-07-26 2001-07-26 Method
GB0118251.8 2001-07-26

Publications (1)

Publication Number Publication Date
CN1533271A true CN1533271A (zh) 2004-09-29

Family

ID=9919248

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028145801A Pending CN1533271A (zh) 2001-07-26 2002-07-25 在光化疗法中作为光敏化剂的5-氨基乙酰丙酸及其酯与另一光敏剂的组合,以及它们在治疗创伤中的用途

Country Status (13)

Country Link
US (1) US20040259949A1 (https=)
EP (1) EP1414430A2 (https=)
JP (1) JP2005501050A (https=)
KR (1) KR20040030863A (https=)
CN (1) CN1533271A (https=)
CA (1) CA2454136A1 (https=)
CZ (1) CZ2004257A3 (https=)
GB (1) GB0118251D0 (https=)
HU (1) HUP0401192A3 (https=)
MX (1) MXPA04000647A (https=)
NO (1) NO20040321L (https=)
RU (1) RU2004105655A (https=)
WO (1) WO2003011265A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101056626B (zh) * 2004-11-10 2011-12-14 弗托库尔公司 利用5-氨基乙酰丙酸衍生物治疗痤疮
CN103717215A (zh) * 2011-06-16 2014-04-09 思佰益药业股份有限公司 过敏性鼻炎的治疗剂
CN105288619A (zh) * 2008-04-04 2016-02-03 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
CN105555312A (zh) * 2013-06-19 2016-05-04 思佰益药业股份有限公司 用于促进生成原卟啉ix的药物组合物
CN109453408A (zh) * 2018-11-16 2019-03-12 江南大学 抗菌创伤敷料及其制备方法
CN112062713A (zh) * 2020-08-04 2020-12-11 浙江工业大学 具铁螯合性和pdt活性的ala-hpo杂合衍生物及其制备方法与应用

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GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
NL1020336C2 (nl) * 2002-04-09 2003-10-13 Photobiochem Leiden N V Toepassing van een verbinding voor de bereiding van een farmaceutisch preparaat voor het behandelen van brandwonden, en een werkwijze voor het behandelen van brandwonden.
NL1022597C2 (nl) * 2003-02-05 2004-08-06 Photobiochem N V Toepassing van een fotosensitizerverbinding voor de bereiding van een farmaceutisch preparaat, werkwijze voor het bereiden van een farmaceutisch preparaat en een werkwijze voor het behandelen van een zoogdier.
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
GB0420888D0 (en) * 2004-09-20 2004-10-20 Photopharmica Ltd Compounds and uses
WO2008006083A2 (en) 2006-07-07 2008-01-10 Surmodics, Inc. Beaded wound spacer device
US20090264492A1 (en) * 2006-08-29 2009-10-22 Stichting Voor De Technische Wetenschappen Pharmaceutical composition for the treatment of a fungal skin disorder and a method for the preparation thereof
AU2008337067A1 (en) * 2007-12-14 2009-06-25 Photoderma Sa Novel compounds useful in therapeutic and cosmetic methods
RU2395315C1 (ru) * 2008-12-01 2010-07-27 Государственное унитарное предприятие г. Москвы Международный научный и клинический центр "Интермедбиофизхим" (ГУП МНКЦ "Интермедбиофизхим") Способ фотодинамической терапии гнойных ран и трофических язв
GB0823472D0 (en) 2008-12-23 2009-01-28 Photocure Asa Product
GB0900461D0 (en) * 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
RU2526803C2 (ru) 2009-06-11 2014-08-27 ФотоКьюэр АСА Полутвердые композиции и фармацевтические продукты
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB0914286D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Method
CA2790827A1 (en) 2010-03-01 2011-09-09 Photocure Asa Cosmetic compositions
EP2585111A1 (en) 2010-06-23 2013-05-01 Photocure ASA Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent
JP5991970B2 (ja) 2010-07-09 2016-09-14 フォトキュア エイエスエイ 光力学的治療または光力学的診断で使用する乾燥組成物および当該乾燥組成物を含む装置
WO2012012616A1 (en) * 2010-07-21 2012-01-26 Patty-Fu Giles Photoactive vitamin nanoparticles for the treatment of chronic wounds
CA2819810A1 (en) * 2010-12-06 2012-06-14 The University Of British Columbia Granzyme b inhibitor compositions, methods and uses for promoting wound healing
WO2012086802A1 (ja) 2010-12-24 2012-06-28 アークレイ株式会社 癌細胞の検出方法
KR101254752B1 (ko) * 2011-02-28 2013-04-15 부산대학교 산학협력단 광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머
KR101254758B1 (ko) * 2011-02-28 2013-04-15 부산대학교병원 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머
US20140316534A1 (en) 2011-10-14 2014-10-23 Photocure Asa Stent
EP2766049A1 (en) 2011-10-14 2014-08-20 Photocure ASA Photodynamic diagnosis of abnormalities of the epithelial lining of the oesophagus with the means of a 5-ala ester
RU2615870C2 (ru) 2011-12-19 2017-04-11 ФотоКьюэр АСА Устройство облучения
WO2014062839A1 (en) 2012-10-16 2014-04-24 Surmodics, Inc. Wound packing device and methods
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
RU2604399C1 (ru) * 2015-12-01 2016-12-10 Сергей Владимирович Москвин Способ лазерной терапии больных трофическими язвами
RU2661084C1 (ru) * 2017-07-21 2018-07-11 Федеральное Агентство Научных Организаций Федеральное Государственное Бюджетное Научное Учреждение "Федеральный Научно-Клинический Центр Реаниматологии И Реабилитологии" (Фнкц Рр) Способ комплексного лечения пролежней у пациентов с длительной иммобилизацией

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234940A (en) * 1989-07-28 1993-08-10 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5913884A (en) * 1996-09-19 1999-06-22 The General Hospital Corporation Inhibition of fibrosis by photodynamic therapy
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101056626B (zh) * 2004-11-10 2011-12-14 弗托库尔公司 利用5-氨基乙酰丙酸衍生物治疗痤疮
CN105288619A (zh) * 2008-04-04 2016-02-03 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
CN103717215A (zh) * 2011-06-16 2014-04-09 思佰益药业股份有限公司 过敏性鼻炎的治疗剂
CN103717215B (zh) * 2011-06-16 2016-08-17 思佰益药业股份有限公司 过敏性鼻炎的治疗剂
CN105555312A (zh) * 2013-06-19 2016-05-04 思佰益药业股份有限公司 用于促进生成原卟啉ix的药物组合物
CN109453408A (zh) * 2018-11-16 2019-03-12 江南大学 抗菌创伤敷料及其制备方法
CN112062713A (zh) * 2020-08-04 2020-12-11 浙江工业大学 具铁螯合性和pdt活性的ala-hpo杂合衍生物及其制备方法与应用

Also Published As

Publication number Publication date
WO2003011265A3 (en) 2003-04-24
HUP0401192A3 (en) 2005-07-28
MXPA04000647A (es) 2004-05-17
WO2003011265A2 (en) 2003-02-13
US20040259949A1 (en) 2004-12-23
GB0118251D0 (en) 2001-09-19
JP2005501050A (ja) 2005-01-13
NO20040321L (no) 2004-03-19
CA2454136A1 (en) 2003-02-13
EP1414430A2 (en) 2004-05-06
CZ2004257A3 (cs) 2004-08-18
RU2004105655A (ru) 2005-04-10
KR20040030863A (ko) 2004-04-09
HUP0401192A2 (hu) 2004-12-28

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