MXPA04000647A - Acido 5-aminolevulinico y sus esteres, en combinacion con otro fotosensibilizador, como agentes fotosensibilizadores en fotoquimioterapia y sus usos en el tratamiento de heridas. - Google Patents
Acido 5-aminolevulinico y sus esteres, en combinacion con otro fotosensibilizador, como agentes fotosensibilizadores en fotoquimioterapia y sus usos en el tratamiento de heridas.Info
- Publication number
- MXPA04000647A MXPA04000647A MXPA04000647A MXPA04000647A MXPA04000647A MX PA04000647 A MXPA04000647 A MX PA04000647A MX PA04000647 A MXPA04000647 A MX PA04000647A MX PA04000647 A MXPA04000647 A MX PA04000647A MX PA04000647 A MXPA04000647 A MX PA04000647A
- Authority
- MX
- Mexico
- Prior art keywords
- aminolevulinic acid
- ulcers
- phtosensitizer
- photochemotherapy
- esters
- Prior art date
Links
- 208000027418 Wounds and injury Diseases 0.000 title abstract 7
- 206010052428 Wound Diseases 0.000 title abstract 5
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002749 aminolevulinic acid Drugs 0.000 title abstract 3
- 239000003504 photosensitizing agent Substances 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- 230000006378 damage Effects 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000035874 Excoriation Diseases 0.000 abstract 1
- 208000034693 Laceration Diseases 0.000 abstract 1
- 208000005230 Leg Ulcer Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 208000000558 Varicose Ulcer Diseases 0.000 abstract 1
- 238000005299 abrasion Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000035790 physiological processes and functions Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El metodo concierne al uso de un fotosensibilizador seleccionado del acido 5-aminolevulinico (5-ALA) y derivados de 5-ALA, y sales de los mismos aceptables farmaceuticamente, en la fabricacion de un medicamento para uso al tratar una herida. Ejemplos de heridas que pueden ser tratadas de conformidad con la invencion, incluyen aquellas que resultan de procesos no fisiologicos, por ejemplo de cirugia o de danos fisicos, abrasiones, laceraciones, y heridas procedentes de un dano termico (por ejemplo una quemadura o una herida procedente de cualquier tratamiento basado en la criogenia). Tambien pueden tratarse exitosamente ulceras, por ejemplo ulceras de las piernas, ulceras venosas y ulceras gastricas, de conformidad con los metodos de la invencion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0118251.8A GB0118251D0 (en) | 2001-07-26 | 2001-07-26 | Method |
| PCT/GB2002/003386 WO2003011265A2 (en) | 2001-07-26 | 2002-07-25 | 5-aminolevulinic acid and esters, in combination with another phtosensitizer, as photosensitizing agents in photochemotherapy, and their uses in treating wounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04000647A true MXPA04000647A (es) | 2004-05-17 |
Family
ID=9919248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04000647A MXPA04000647A (es) | 2001-07-26 | 2002-07-25 | Acido 5-aminolevulinico y sus esteres, en combinacion con otro fotosensibilizador, como agentes fotosensibilizadores en fotoquimioterapia y sus usos en el tratamiento de heridas. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040259949A1 (es) |
| EP (1) | EP1414430A2 (es) |
| JP (1) | JP2005501050A (es) |
| KR (1) | KR20040030863A (es) |
| CN (1) | CN1533271A (es) |
| CA (1) | CA2454136A1 (es) |
| CZ (1) | CZ2004257A3 (es) |
| GB (1) | GB0118251D0 (es) |
| HU (1) | HUP0401192A3 (es) |
| MX (1) | MXPA04000647A (es) |
| NO (1) | NO20040321L (es) |
| RU (1) | RU2004105655A (es) |
| WO (1) | WO2003011265A2 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0018528D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| NL1020336C2 (nl) * | 2002-04-09 | 2003-10-13 | Photobiochem Leiden N V | Toepassing van een verbinding voor de bereiding van een farmaceutisch preparaat voor het behandelen van brandwonden, en een werkwijze voor het behandelen van brandwonden. |
| NL1022597C2 (nl) * | 2003-02-05 | 2004-08-06 | Photobiochem N V | Toepassing van een fotosensitizerverbinding voor de bereiding van een farmaceutisch preparaat, werkwijze voor het bereiden van een farmaceutisch preparaat en een werkwijze voor het behandelen van een zoogdier. |
| US20050154052A1 (en) * | 2003-03-24 | 2005-07-14 | Hetero Drugs Limited | Novel crystalline forms of (s)-citalopram oxalate |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0420888D0 (en) * | 2004-09-20 | 2004-10-20 | Photopharmica Ltd | Compounds and uses |
| GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| US8685421B2 (en) | 2006-07-07 | 2014-04-01 | Surmodics, Inc. | Beaded wound spacer device |
| ATE454146T1 (de) * | 2006-08-29 | 2010-01-15 | Stichting Tech Wetenschapp | Pharmazeutische zusammensetzung zur behandlung von mykotischen hauterkrankungen und verfahren zu ihrer herstellung |
| US8492578B2 (en) * | 2007-12-14 | 2013-07-23 | Photoderma Sa | Compounds useful in therapeutic and cosmetic methods |
| JP5967935B2 (ja) * | 2008-04-04 | 2016-08-10 | イミュノライト・エルエルシー | ｉｎｓｉｔｕでのフォトバイオモデュレーションのための非侵襲性システムおよび方法 |
| GB0823472D0 (en) | 2008-12-23 | 2009-01-28 | Photocure Asa | Product |
| GB0900461D0 (en) * | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
| HUE026911T2 (en) | 2009-06-11 | 2016-07-28 | Photocure Asa | Semi-solid preparations and medical products |
| GB0914287D0 (en) | 2009-08-14 | 2009-09-30 | Pci Biotech As | Compositions |
| GB0914286D0 (en) * | 2009-08-14 | 2009-09-30 | Pci Biotech As | Method |
| MX2012010007A (es) | 2010-03-01 | 2012-10-01 | Photocure Asa | Composiciones cosmeticas. |
| EP2585111A1 (en) | 2010-06-23 | 2013-05-01 | Photocure ASA | Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent |
| KR101842732B1 (ko) | 2010-07-09 | 2018-05-14 | 포토큐어 에이에스에이 | 광역동 치료 또는 광역동 진단에 사용하기 위한 건조 조성물 및 이와 같은 건조 조성물을 포함하는 기구 |
| US20130245598A1 (en) * | 2010-07-21 | 2013-09-19 | Patty Fu-Giles | Photoactive vitamin nanoparticles for the treatment of chronic wounds |
| EP2648735A4 (en) * | 2010-12-06 | 2014-07-30 | Univ British Columbia | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING HEALING |
| JP6323978B2 (ja) | 2010-12-24 | 2018-05-16 | アークレイ株式会社 | 癌細胞の検出方法 |
| KR101254758B1 (ko) * | 2011-02-28 | 2013-04-15 | 부산대학교병원 | 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머 |
| KR101254752B1 (ko) * | 2011-02-28 | 2013-04-15 | 부산대학교 산학협력단 | 광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머 |
| CN103717215B (zh) * | 2011-06-16 | 2016-08-17 | 思佰益药业股份有限公司 | 过敏性鼻炎的治疗剂 |
| US20140276107A1 (en) | 2011-10-14 | 2014-09-18 | Photocure Asa | Photodynamic diagnosis |
| EP2779956A1 (en) | 2011-10-14 | 2014-09-24 | Photocure ASA | Stent |
| BR112014014847B1 (pt) | 2011-12-19 | 2022-08-16 | Photocure Asa | Aparelho de aplicação de luz portátil, autônomo, para tratamento fotodinâmico da vulva, e kit |
| WO2014062839A1 (en) | 2012-10-16 | 2014-04-24 | Surmodics, Inc. | Wound packing device and methods |
| GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
| EP3011972B1 (en) * | 2013-06-19 | 2019-10-23 | SBI Pharmaceuticals Co., Ltd. | Medicinal composition for promoting synthesis of protoporphyrin ix |
| US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
| RU2604399C1 (ru) * | 2015-12-01 | 2016-12-10 | Сергей Владимирович Москвин | Способ лазерной терапии больных трофическими язвами |
| RU2661084C1 (ru) * | 2017-07-21 | 2018-07-11 | Федеральное Агентство Научных Организаций Федеральное Государственное Бюджетное Научное Учреждение "Федеральный Научно-Клинический Центр Реаниматологии И Реабилитологии" (Фнкц Рр) | Способ комплексного лечения пролежней у пациентов с длительной иммобилизацией |
| CN109453408A (zh) * | 2018-11-16 | 2019-03-12 | 江南大学 | 抗菌创伤敷料及其制备方法 |
| CN112062713B (zh) * | 2020-08-04 | 2023-03-31 | 浙江工业大学 | 具铁螯合性和pdt活性的ala-hpo杂合衍生物及其制备方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234940A (en) * | 1989-07-28 | 1993-08-10 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
| US5913884A (en) * | 1996-09-19 | 1999-06-22 | The General Hospital Corporation | Inhibition of fibrosis by photodynamic therapy |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
-
2001
- 2001-07-26 GB GBGB0118251.8A patent/GB0118251D0/en not_active Ceased
-
2002
- 2002-07-25 KR KR10-2004-7001165A patent/KR20040030863A/ko not_active Application Discontinuation
- 2002-07-25 CZ CZ2004257A patent/CZ2004257A3/cs unknown
- 2002-07-25 EP EP02747590A patent/EP1414430A2/en not_active Withdrawn
- 2002-07-25 WO PCT/GB2002/003386 patent/WO2003011265A2/en not_active Application Discontinuation
- 2002-07-25 MX MXPA04000647A patent/MXPA04000647A/es unknown
- 2002-07-25 US US10/484,743 patent/US20040259949A1/en not_active Abandoned
- 2002-07-25 JP JP2003516496A patent/JP2005501050A/ja active Pending
- 2002-07-25 CN CNA028145801A patent/CN1533271A/zh active Pending
- 2002-07-25 CA CA002454136A patent/CA2454136A1/en not_active Abandoned
- 2002-07-25 HU HU0401192A patent/HUP0401192A3/hu unknown
- 2002-07-25 RU RU2004105655/15A patent/RU2004105655A/ru not_active Application Discontinuation
-
2004
- 2004-01-23 NO NO20040321A patent/NO20040321L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2004257A3 (cs) | 2004-08-18 |
| RU2004105655A (ru) | 2005-04-10 |
| HUP0401192A3 (en) | 2005-07-28 |
| JP2005501050A (ja) | 2005-01-13 |
| KR20040030863A (ko) | 2004-04-09 |
| WO2003011265A3 (en) | 2003-04-24 |
| NO20040321L (no) | 2004-03-19 |
| CA2454136A1 (en) | 2003-02-13 |
| HUP0401192A2 (hu) | 2004-12-28 |
| US20040259949A1 (en) | 2004-12-23 |
| CN1533271A (zh) | 2004-09-29 |
| GB0118251D0 (en) | 2001-09-19 |
| WO2003011265A2 (en) | 2003-02-13 |
| EP1414430A2 (en) | 2004-05-06 |
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