NO20040321L - 5-aminolevulinsyre og estere i kombinasjon med andre fotosensibilisatorer, som fotosensibilisatoriske midler i fotokjemiterapi og deres anvendelser i behandling av sar - Google Patents
5-aminolevulinsyre og estere i kombinasjon med andre fotosensibilisatorer, som fotosensibilisatoriske midler i fotokjemiterapi og deres anvendelser i behandling av sarInfo
- Publication number
- NO20040321L NO20040321L NO20040321A NO20040321A NO20040321L NO 20040321 L NO20040321 L NO 20040321L NO 20040321 A NO20040321 A NO 20040321A NO 20040321 A NO20040321 A NO 20040321A NO 20040321 L NO20040321 L NO 20040321L
- Authority
- NO
- Norway
- Prior art keywords
- photosensitizers
- ulcers
- aminolevulinic acid
- photochemistry
- esters
- Prior art date
Links
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002749 aminolevulinic acid Drugs 0.000 title abstract 3
- 239000003504 photosensitizing agent Substances 0.000 title abstract 3
- 208000025865 Ulcer Diseases 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- 231100000397 ulcer Toxicity 0.000 title 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 6
- 206010052428 Wound Diseases 0.000 abstract 4
- 230000006378 damage Effects 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000035874 Excoriation Diseases 0.000 abstract 1
- 208000034693 Laceration Diseases 0.000 abstract 1
- 208000005230 Leg Ulcer Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 208000000558 Varicose Ulcer Diseases 0.000 abstract 1
- 238000005299 abrasion Methods 0.000 abstract 1
- 238000000315 cryotherapy Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000035790 physiological processes and functions Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det beskrives en fremgangsmåte for anvendelse av et fotosensibiliserende middel valgt fra 5-aminolevulinsyre (5-ALA) og 5-ALA-derivater, og farmasøytisk akseptable salter derav, ved fremstillingen av et medikament til behandling av et sår. Eksempler på sår som kan behandles i overensstemmelse med oppfinnelsen er slike som skriver seg fra ikke-fysiologiske prosesser, feks. fra kirurgi eller fra fysisk skade, abrasjoner, laserasjoner, og sår som skriver seg fra termisk skade (feks. forbrenning, eller et sår som skriver seg fra en hvilken som helst kryoterapi).Ulcerasjoner, feks. leggsår, venøse sår og mavesår, kan også med hell behandles i overensstemmelse med fremgangsmåtene ifølge oppfinnelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0118251.8A GB0118251D0 (en) | 2001-07-26 | 2001-07-26 | Method |
PCT/GB2002/003386 WO2003011265A2 (en) | 2001-07-26 | 2002-07-25 | 5-aminolevulinic acid and esters, in combination with another phtosensitizer, as photosensitizing agents in photochemotherapy, and their uses in treating wounds |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20040321L true NO20040321L (no) | 2004-03-19 |
Family
ID=9919248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20040321A NO20040321L (no) | 2001-07-26 | 2004-01-23 | 5-aminolevulinsyre og estere i kombinasjon med andre fotosensibilisatorer, som fotosensibilisatoriske midler i fotokjemiterapi og deres anvendelser i behandling av sar |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040259949A1 (no) |
EP (1) | EP1414430A2 (no) |
JP (1) | JP2005501050A (no) |
KR (1) | KR20040030863A (no) |
CN (1) | CN1533271A (no) |
CA (1) | CA2454136A1 (no) |
CZ (1) | CZ2004257A3 (no) |
GB (1) | GB0118251D0 (no) |
HU (1) | HUP0401192A3 (no) |
MX (1) | MXPA04000647A (no) |
NO (1) | NO20040321L (no) |
RU (1) | RU2004105655A (no) |
WO (1) | WO2003011265A2 (no) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0018528D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
NL1020336C2 (nl) * | 2002-04-09 | 2003-10-13 | Photobiochem Leiden N V | Toepassing van een verbinding voor de bereiding van een farmaceutisch preparaat voor het behandelen van brandwonden, en een werkwijze voor het behandelen van brandwonden. |
NL1022597C2 (nl) * | 2003-02-05 | 2004-08-06 | Photobiochem N V | Toepassing van een fotosensitizerverbinding voor de bereiding van een farmaceutisch preparaat, werkwijze voor het bereiden van een farmaceutisch preparaat en een werkwijze voor het behandelen van een zoogdier. |
US20050154052A1 (en) * | 2003-03-24 | 2005-07-14 | Hetero Drugs Limited | Novel crystalline forms of (s)-citalopram oxalate |
GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
GB0420888D0 (en) * | 2004-09-20 | 2004-10-20 | Photopharmica Ltd | Compounds and uses |
GB0424833D0 (en) | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
US8685421B2 (en) | 2006-07-07 | 2014-04-01 | Surmodics, Inc. | Beaded wound spacer device |
AU2007289419A1 (en) * | 2006-08-29 | 2008-03-06 | Stichting Voor De Technische Wetenschappen | A pharmaceutical composition for the treatment of a fungal skin disorder and a method for the preparation thereof |
AU2008337067A1 (en) * | 2007-12-14 | 2009-06-25 | Photoderma Sa | Novel compounds useful in therapeutic and cosmetic methods |
CN102056625B (zh) * | 2008-04-04 | 2015-11-25 | 免疫之光有限责任公司 | 用于原位光生物调节的非侵入性系统和方法 |
GB0823472D0 (en) | 2008-12-23 | 2009-01-28 | Photocure Asa | Product |
GB0900461D0 (en) | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
ES2821831T3 (es) | 2009-06-11 | 2021-04-27 | Photocure Asa | Composiciones y productos farmacéuticos semisólidos que comprenden ésteres de ácido 5-aminolevulínico |
GB0914287D0 (en) | 2009-08-14 | 2009-09-30 | Pci Biotech As | Compositions |
GB0914286D0 (en) * | 2009-08-14 | 2009-09-30 | Pci Biotech As | Method |
WO2011107478A1 (en) | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
US20130211215A1 (en) | 2010-06-23 | 2013-08-15 | Photocure Asa | Hyperosmotic preparations comprising 5-aminolevulinic acid or derivative as photosensitizing agent |
KR101842732B1 (ko) | 2010-07-09 | 2018-05-14 | 포토큐어 에이에스에이 | 광역동 치료 또는 광역동 진단에 사용하기 위한 건조 조성물 및 이와 같은 건조 조성물을 포함하는 기구 |
CN103189105A (zh) * | 2010-07-21 | 2013-07-03 | P·傅贾尔斯 | 治疗慢性创伤的光活性维生素纳米颗粒 |
WO2012076985A2 (en) * | 2010-12-06 | 2012-06-14 | The University Of British Columbia | Granzyme b inhibitor compositions, methods and uses for promoting wound healing |
WO2012086802A1 (ja) | 2010-12-24 | 2012-06-28 | アークレイ株式会社 | 癌細胞の検出方法 |
KR101254758B1 (ko) * | 2011-02-28 | 2013-04-15 | 부산대학교병원 | 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머 |
KR101254752B1 (ko) * | 2011-02-28 | 2013-04-15 | 부산대학교 산학협력단 | 광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머 |
JP5713473B2 (ja) * | 2011-06-16 | 2015-05-07 | Sbiファーマ株式会社 | アレルギー性鼻炎の治療剤 |
US20140316534A1 (en) | 2011-10-14 | 2014-10-23 | Photocure Asa | Stent |
EP2766049A1 (en) | 2011-10-14 | 2014-08-20 | Photocure ASA | Photodynamic diagnosis of abnormalities of the epithelial lining of the oesophagus with the means of a 5-ala ester |
BR112014014847B1 (pt) | 2011-12-19 | 2022-08-16 | Photocure Asa | Aparelho de aplicação de luz portátil, autônomo, para tratamento fotodinâmico da vulva, e kit |
CA2888241C (en) | 2012-10-16 | 2020-12-29 | Surmodics, Inc. | Wound packing device and methods |
GB201306369D0 (en) | 2013-04-09 | 2013-05-22 | Photocure As | Irradiation device |
HUE046458T2 (hu) * | 2013-06-19 | 2020-03-30 | Sbi Pharmaceuticals Co Ltd | Gyógyászati készítmény protoporfirin IX szintézisének elõsegítésére |
US10201457B2 (en) | 2014-08-01 | 2019-02-12 | Surmodics, Inc. | Wound packing device with nanotextured surface |
RU2604399C1 (ru) * | 2015-12-01 | 2016-12-10 | Сергей Владимирович Москвин | Способ лазерной терапии больных трофическими язвами |
RU2661084C1 (ru) * | 2017-07-21 | 2018-07-11 | Федеральное Агентство Научных Организаций Федеральное Государственное Бюджетное Научное Учреждение "Федеральный Научно-Клинический Центр Реаниматологии И Реабилитологии" (Фнкц Рр) | Способ комплексного лечения пролежней у пациентов с длительной иммобилизацией |
CN109453408A (zh) * | 2018-11-16 | 2019-03-12 | 江南大学 | 抗菌创伤敷料及其制备方法 |
CN112062713B (zh) * | 2020-08-04 | 2023-03-31 | 浙江工业大学 | 具铁螯合性和pdt活性的ala-hpo杂合衍生物及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5234940A (en) * | 1989-07-28 | 1993-08-10 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
US5913884A (en) * | 1996-09-19 | 1999-06-22 | The General Hospital Corporation | Inhibition of fibrosis by photodynamic therapy |
GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
-
2001
- 2001-07-26 GB GBGB0118251.8A patent/GB0118251D0/en not_active Ceased
-
2002
- 2002-07-25 JP JP2003516496A patent/JP2005501050A/ja active Pending
- 2002-07-25 CZ CZ2004257A patent/CZ2004257A3/cs unknown
- 2002-07-25 KR KR10-2004-7001165A patent/KR20040030863A/ko not_active Application Discontinuation
- 2002-07-25 RU RU2004105655/15A patent/RU2004105655A/ru not_active Application Discontinuation
- 2002-07-25 CN CNA028145801A patent/CN1533271A/zh active Pending
- 2002-07-25 HU HU0401192A patent/HUP0401192A3/hu unknown
- 2002-07-25 MX MXPA04000647A patent/MXPA04000647A/es unknown
- 2002-07-25 EP EP02747590A patent/EP1414430A2/en not_active Withdrawn
- 2002-07-25 US US10/484,743 patent/US20040259949A1/en not_active Abandoned
- 2002-07-25 CA CA002454136A patent/CA2454136A1/en not_active Abandoned
- 2002-07-25 WO PCT/GB2002/003386 patent/WO2003011265A2/en not_active Application Discontinuation
-
2004
- 2004-01-23 NO NO20040321A patent/NO20040321L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1414430A2 (en) | 2004-05-06 |
RU2004105655A (ru) | 2005-04-10 |
CA2454136A1 (en) | 2003-02-13 |
WO2003011265A3 (en) | 2003-04-24 |
WO2003011265A2 (en) | 2003-02-13 |
MXPA04000647A (es) | 2004-05-17 |
CZ2004257A3 (cs) | 2004-08-18 |
CN1533271A (zh) | 2004-09-29 |
KR20040030863A (ko) | 2004-04-09 |
HUP0401192A2 (hu) | 2004-12-28 |
JP2005501050A (ja) | 2005-01-13 |
HUP0401192A3 (en) | 2005-07-28 |
GB0118251D0 (en) | 2001-09-19 |
US20040259949A1 (en) | 2004-12-23 |
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