CN1516706A - 人g蛋白偶联受体的内源性和非内源性形式 - Google Patents

人g蛋白偶联受体的内源性和非内源性形式 Download PDF

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Publication number
CN1516706A
CN1516706A CNA028087879A CN02808787A CN1516706A CN 1516706 A CN1516706 A CN 1516706A CN A028087879 A CNA028087879 A CN A028087879A CN 02808787 A CN02808787 A CN 02808787A CN 1516706 A CN1516706 A CN 1516706A
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China
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val
ala
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ser
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Pending
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CNA028087879A
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English (en)
Chinese (zh)
Inventor
廖王蓁
查尔默斯
D·T·查尔默斯
贝汉
D·P·贝汉
幸夫斯基-莱尼奥尔
D·马切耶夫斯基－莱尼奥尔
莱昂纳德
J·N·莱昂纳德
图诺
林伊玲
D·奥尔图诺
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Arena Pharmaceuticals Inc
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Arena Pharmaceuticals Inc
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Application filed by Arena Pharmaceuticals Inc filed Critical Arena Pharmaceuticals Inc
Publication of CN1516706A publication Critical patent/CN1516706A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNA028087879A 2001-02-26 2002-02-26 人g蛋白偶联受体的内源性和非内源性形式 Pending CN1516706A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27191301P 2001-02-26 2001-02-26
US60/271,913 2001-02-26

Publications (1)

Publication Number Publication Date
CN1516706A true CN1516706A (zh) 2004-07-28

Family

ID=23037612

Family Applications (1)

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CNA028087879A Pending CN1516706A (zh) 2001-02-26 2002-02-26 人g蛋白偶联受体的内源性和非内源性形式

Country Status (5)

Country Link
EP (1) EP1412372A4 (ja)
JP (1) JP2004526441A (ja)
CN (1) CN1516706A (ja)
CA (1) CA2439383A1 (ja)
WO (1) WO2002068600A2 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7115375B2 (en) 2000-11-14 2006-10-03 Bristol-Myers Squibb Methods of diagnosing renal tumors by determining the expression level of RNA encoding the HGPRBMY18 polypeptide
WO2004013638A1 (en) * 2002-07-31 2004-02-12 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human g-protein coupled receptor 45 (gpr45)
WO2004013637A1 (en) * 2002-08-01 2004-02-12 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 37 (gpr37)
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
AU2004220864B2 (en) * 2003-03-17 2011-05-26 Arena Pharmaceuticals Inc. Modulators of G Protein-Coupled Formyl peptide receptor-like 2 and their therapeutic use against cell death-related disorders
US7517661B2 (en) 2003-04-23 2009-04-14 Takeda Pharmaceutical Company Limited Methods of screening for ligands for FPRL2
JP4533655B2 (ja) * 2003-04-23 2010-09-01 武田薬品工業株式会社 新規スクリーニング方法
WO2005059546A2 (en) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 35 (gpr35)
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
WO2006005588A1 (en) * 2004-07-12 2006-01-19 Geneprot, Inc. Polypeptide species useful for the treatment of neurological disorders
EP1788390B1 (en) * 2004-08-30 2010-04-14 Takeda Pharmaceutical Company Limited Screening method
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
DK2121919T3 (da) * 2007-03-22 2012-05-21 Heptares Therapeutics Ltd Mutante g-proteinkoblede receptorer og fremgangsmåder til udvælgelse heraf
GB0724051D0 (en) 2007-12-08 2008-01-16 Medical Res Council Mutant proteins and methods for producing them
GB0724860D0 (en) 2007-12-20 2008-01-30 Heptares Therapeutics Ltd Screening
GB0802474D0 (en) 2008-02-11 2008-03-19 Heptares Therapeutics Ltd Mutant proteins and methods for selecting them
GB0910725D0 (en) 2009-06-22 2009-08-05 Heptares Therapeutics Ltd Mutant proteins and methods for producing them
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
CN105073776B (zh) 2012-11-13 2019-04-12 拜恩科技股份公司 用于治疗表达紧密连接蛋白的癌症疾病的制剂
GB201601690D0 (en) 2016-01-29 2016-03-16 Heptares Therapeutics Ltd G proteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001501097A (ja) * 1996-09-24 2001-01-30 ケイダス ファーマスーティカル コーポレイション レセプターエフェクターを同定する方法及び組成物
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors

Also Published As

Publication number Publication date
WO2002068600A2 (en) 2002-09-06
JP2004526441A (ja) 2004-09-02
EP1412372A2 (en) 2004-04-28
CA2439383A1 (en) 2002-09-06
EP1412372A4 (en) 2005-08-24
WO2002068600A3 (en) 2004-02-26

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