EP1412372A4 - ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G-PROTEIN COUPLED RECEPTORS - Google Patents

ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G-PROTEIN COUPLED RECEPTORS

Info

Publication number
EP1412372A4
EP1412372A4 EP02717500A EP02717500A EP1412372A4 EP 1412372 A4 EP1412372 A4 EP 1412372A4 EP 02717500 A EP02717500 A EP 02717500A EP 02717500 A EP02717500 A EP 02717500A EP 1412372 A4 EP1412372 A4 EP 1412372A4
Authority
EP
European Patent Office
Prior art keywords
endogenous
protein
human
coupled receptors
versions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02717500A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1412372A2 (en
Inventor
Chen W Liaw
Derek T Chalmers
Dominic P Behan
Dominique Maciejewski-Lenior
James N Leonard
I-Lin Lin
Daniel Ortuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arena Pharmaceuticals Inc
Original Assignee
Arena Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharmaceuticals Inc filed Critical Arena Pharmaceuticals Inc
Publication of EP1412372A2 publication Critical patent/EP1412372A2/en
Publication of EP1412372A4 publication Critical patent/EP1412372A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP02717500A 2001-02-26 2002-02-26 ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G-PROTEIN COUPLED RECEPTORS Withdrawn EP1412372A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27191301P 2001-02-26 2001-02-26
US271913P 2001-02-26
PCT/US2002/005625 WO2002068600A2 (en) 2001-02-26 2002-02-26 Endogenous and non-endogenous versions of human g protein-coupled receptors

Publications (2)

Publication Number Publication Date
EP1412372A2 EP1412372A2 (en) 2004-04-28
EP1412372A4 true EP1412372A4 (en) 2005-08-24

Family

ID=23037612

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02717500A Withdrawn EP1412372A4 (en) 2001-02-26 2002-02-26 ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G-PROTEIN COUPLED RECEPTORS

Country Status (5)

Country Link
EP (1) EP1412372A4 (ja)
JP (1) JP2004526441A (ja)
CN (1) CN1516706A (ja)
CA (1) CA2439383A1 (ja)
WO (1) WO2002068600A2 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7115375B2 (en) 2000-11-14 2006-10-03 Bristol-Myers Squibb Methods of diagnosing renal tumors by determining the expression level of RNA encoding the HGPRBMY18 polypeptide
WO2004013638A1 (en) * 2002-07-31 2004-02-12 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human g-protein coupled receptor 45 (gpr45)
WO2004013637A1 (en) * 2002-08-01 2004-02-12 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 37 (gpr37)
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
AU2004220864B2 (en) * 2003-03-17 2011-05-26 Arena Pharmaceuticals Inc. Modulators of G Protein-Coupled Formyl peptide receptor-like 2 and their therapeutic use against cell death-related disorders
US7517661B2 (en) 2003-04-23 2009-04-14 Takeda Pharmaceutical Company Limited Methods of screening for ligands for FPRL2
JP4533655B2 (ja) * 2003-04-23 2010-09-01 武田薬品工業株式会社 新規スクリーニング方法
WO2005059546A2 (en) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 35 (gpr35)
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
WO2006005588A1 (en) * 2004-07-12 2006-01-19 Geneprot, Inc. Polypeptide species useful for the treatment of neurological disorders
EP1788390B1 (en) * 2004-08-30 2010-04-14 Takeda Pharmaceutical Company Limited Screening method
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
DK2121919T3 (da) * 2007-03-22 2012-05-21 Heptares Therapeutics Ltd Mutante g-proteinkoblede receptorer og fremgangsmåder til udvælgelse heraf
GB0724051D0 (en) 2007-12-08 2008-01-16 Medical Res Council Mutant proteins and methods for producing them
GB0724860D0 (en) 2007-12-20 2008-01-30 Heptares Therapeutics Ltd Screening
GB0802474D0 (en) 2008-02-11 2008-03-19 Heptares Therapeutics Ltd Mutant proteins and methods for selecting them
GB0910725D0 (en) 2009-06-22 2009-08-05 Heptares Therapeutics Ltd Mutant proteins and methods for producing them
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
CN105073776B (zh) 2012-11-13 2019-04-12 拜恩科技股份公司 用于治疗表达紧密连接蛋白的癌症疾病的制剂
GB201601690D0 (en) 2016-01-29 2016-03-16 Heptares Therapeutics Ltd G proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022129A1 (en) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human g protein-coupled receptors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001501097A (ja) * 1996-09-24 2001-01-30 ケイダス ファーマスーティカル コーポレイション レセプターエフェクターを同定する方法及び組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022129A1 (en) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human g protein-coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARAZZITI D ET AL: "CLONING OF GPR37, A GENE LOCATED ON CHROMOSOME 7 ENCODING A PUTATIVE G-PROTEIN-COUPLED PEPTIDE RECEPTOR, FROM A HUMAN FRONTAL BRAIN EST LIBRARY", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 45, 1997, pages 68 - 77, XP002936018, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
WO2002068600A2 (en) 2002-09-06
JP2004526441A (ja) 2004-09-02
CN1516706A (zh) 2004-07-28
EP1412372A2 (en) 2004-04-28
CA2439383A1 (en) 2002-09-06
WO2002068600A3 (en) 2004-02-26

Similar Documents

Publication Publication Date Title
IL149569A0 (en) Endogenous and non-endogenous versions of human g protein-coupled receptors
EP1412372A4 (en) ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G-PROTEIN COUPLED RECEPTORS
EP1549614A4 (en) VASCULATORY AGENTS AND METHODS FOR THEIR APPLICATION
IL165280A0 (en) 4-Substituted imidazole-2-thiones and imidazol-2-ones as agpmosts of the alpha-2b and alpha-2c adrenergic receptors
AU1989002A (en) Endogenous and non-endogenous versions of human g protein-coupled receptors
PL375784A1 (en) Use of erythopoietin
AU2003279841A8 (en) Uses of human zven antagonists
AU2003239868A8 (en) Sunscreen compositions and methods of use thereof
AU2002351175A8 (en) Novel human g-protein coupled receptor, hgprbmy31, and variants and methods of use thereof
AU2002309970A8 (en) Receptors and membrane-associated proteins
EP1461450A4 (en) T-BET COMPOSITIONS AND METHOD OF USE THEREOF
AU2001281791A1 (en) Regulation of human lgr4-like g protein-coupled receptor
AU2001260147A1 (en) Regulation of human rta-like g protein-coupled receptor
AU2002326834A8 (en) Anopheles gambiae odorant receptors and genes
EP1424557A4 (en) USE OF A G-PROTEIN-COUPLED RECEPTOR PROTEIN
AU2003220085A8 (en) Protein a compositions and methods of use
IL161608A0 (en) Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
AU2001263379A1 (en) G protein-coupled receptors from human clone "26908" and uses thereof
AU6012901A (en) Regulation of human g protein-coupled receptor
AU2001242485A1 (en) Regulation of human serotonin-like g protein-coupled receptor
AU2003210644A8 (en) Non-endogenous versions of human g protein-coupled receptor: fshr
AU2002226406A1 (en) Human g protein-coupled receptors and uses thereof
AU2002225030A1 (en) Regulation of human serotonin-like g protein-coupled receptor
AU2001274112A1 (en) Regulation of human rta-like g protein-coupled receptor
AU2002364149A8 (en) Novel human g-protein coupled receptor, hgprbmy34, and variants and methods of use thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030924

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/72 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 12N 15/63 B

Ipc: 7C 12N 15/09 B

Ipc: 7C 07K 14/705 B

Ipc: 7C 07H 21/04 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050704

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050901