CN1494531A - 喹啉-3-羧酸化合物的制备方法 - Google Patents
喹啉-3-羧酸化合物的制备方法 Download PDFInfo
- Publication number
- CN1494531A CN1494531A CNA028058925A CN02805892A CN1494531A CN 1494531 A CN1494531 A CN 1494531A CN A028058925 A CNA028058925 A CN A028058925A CN 02805892 A CN02805892 A CN 02805892A CN 1494531 A CN1494531 A CN 1494531A
- Authority
- CN
- China
- Prior art keywords
- methyl
- expression
- alkyl
- carboxylic acid
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58243/2001 | 2001-03-02 | ||
JP58243/01 | 2001-03-02 | ||
JP2001058243 | 2001-03-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1494531A true CN1494531A (zh) | 2004-05-05 |
CN1234691C CN1234691C (zh) | 2006-01-04 |
Family
ID=18917994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028058925A Expired - Fee Related CN1234691C (zh) | 2001-03-02 | 2002-02-25 | 喹啉-3-羧酸化合物的制备方法 |
Country Status (10)
Country | Link |
---|---|
US (1) | US6852862B2 (zh) |
EP (1) | EP1375487B1 (zh) |
JP (1) | JP4300457B2 (zh) |
KR (1) | KR100835031B1 (zh) |
CN (1) | CN1234691C (zh) |
AT (1) | ATE521594T1 (zh) |
AU (1) | AU2002233708B2 (zh) |
CA (1) | CA2439663C (zh) |
TW (1) | TWI233928B (zh) |
WO (1) | WO2002070488A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103467373A (zh) * | 2013-09-05 | 2013-12-25 | 南京欧信医药技术有限公司 | 一种喹啉类化合物的合成方法 |
CN106107406A (zh) * | 2010-08-12 | 2016-11-16 | 赛诺米克斯公司 | 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100130737A1 (en) * | 2005-02-18 | 2010-05-27 | Takeda Pharmaceutical Company Limited | Regulating Agent of GPR34 Receptor Function |
US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
DK2323997T3 (en) | 2008-07-31 | 2017-12-11 | Senomyx Inc | METHODS AND INTERMEDIATES FOR THE MANUFACTURE OF SWEET TASTE AMPLIFIERS |
WO2010014813A2 (en) | 2008-07-31 | 2010-02-04 | Senomyx, Inc. | Compositions comrpising sweetness enhancers and methods of making them |
PE20150626A1 (es) | 2012-08-06 | 2015-05-29 | Senomyx Inc | Modificador del sabor dulce |
JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
EP3814344A1 (en) | 2018-08-07 | 2021-05-05 | Firmenich Incorporated | 5-substituted 4-amino-1h-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5753675A (en) | 1989-03-03 | 1998-05-19 | Novartis Pharmaceuticals Corporation | Quinoline analogs of mevalonolactone and derivatives thereof |
TW205037B (zh) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
JPH06340658A (ja) * | 1993-04-08 | 1994-12-13 | Kyowa Hakko Kogyo Co Ltd | ベンゾイミダゾール誘導体 |
EP0634169B1 (en) * | 1993-06-29 | 2000-01-05 | Takeda Chemical Industries, Ltd. | Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis |
JPH0769890A (ja) * | 1993-06-29 | 1995-03-14 | Takeda Chem Ind Ltd | キノリンまたはキナゾリン誘導体を含んでなる医薬組成物 |
WO1995024394A1 (en) * | 1994-03-08 | 1995-09-14 | Takeda Chemical Industries, Ltd. | Quinoline or quinazoline derivatives as anti-inflammatory agents, in particular for treating arthritis |
-
2002
- 2002-02-25 JP JP2002569808A patent/JP4300457B2/ja not_active Expired - Fee Related
- 2002-02-25 WO PCT/JP2002/001645 patent/WO2002070488A1/ja active Application Filing
- 2002-02-25 KR KR1020037011495A patent/KR100835031B1/ko not_active IP Right Cessation
- 2002-02-25 CA CA2439663A patent/CA2439663C/en not_active Expired - Fee Related
- 2002-02-25 EP EP02700735A patent/EP1375487B1/en not_active Expired - Lifetime
- 2002-02-25 US US10/468,350 patent/US6852862B2/en not_active Expired - Fee Related
- 2002-02-25 AU AU2002233708A patent/AU2002233708B2/en not_active Ceased
- 2002-02-25 CN CNB028058925A patent/CN1234691C/zh not_active Expired - Fee Related
- 2002-02-25 AT AT02700735T patent/ATE521594T1/de not_active IP Right Cessation
- 2002-03-01 TW TW091103838A patent/TWI233928B/zh not_active IP Right Cessation
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106107406A (zh) * | 2010-08-12 | 2016-11-16 | 赛诺米克斯公司 | 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物 |
CN106107406B (zh) * | 2010-08-12 | 2020-06-09 | 弗门尼舍公司 | 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物 |
CN103467373A (zh) * | 2013-09-05 | 2013-12-25 | 南京欧信医药技术有限公司 | 一种喹啉类化合物的合成方法 |
CN103467373B (zh) * | 2013-09-05 | 2015-07-08 | 南京欧信医药技术有限公司 | 一种喹啉类化合物的合成方法 |
Also Published As
Publication number | Publication date |
---|---|
EP1375487A1 (en) | 2004-01-02 |
EP1375487B1 (en) | 2011-08-24 |
WO2002070488A1 (fr) | 2002-09-12 |
KR100835031B1 (ko) | 2008-06-03 |
US20040073034A1 (en) | 2004-04-15 |
AU2002233708B2 (en) | 2007-02-08 |
CA2439663C (en) | 2012-04-03 |
EP1375487A4 (en) | 2005-03-02 |
ATE521594T1 (de) | 2011-09-15 |
TWI233928B (en) | 2005-06-11 |
JPWO2002070488A1 (ja) | 2004-09-24 |
KR20030082947A (ko) | 2003-10-23 |
US6852862B2 (en) | 2005-02-08 |
JP4300457B2 (ja) | 2009-07-22 |
CN1234691C (zh) | 2006-01-04 |
CA2439663A1 (en) | 2002-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1234691C (zh) | 喹啉-3-羧酸化合物的制备方法 | |
JP5016575B2 (ja) | ストロンチウムラネレートおよびその水和物の新規な合成法 | |
US7271268B1 (en) | Process for preparation of [1-(mercaptomethyl)cyclopropyl]acetic acid and related derivatives | |
EP1017676B1 (en) | Method for the synthesis of quinoline derivatives | |
KR102453655B1 (ko) | 아코티아미드의 개선된 제조방법 | |
AU2014220865B2 (en) | Asymmetric synthesis of a substituted pyrrolidine-2-carboxamide | |
US7323584B2 (en) | Process for preparing N-(4′-cyano-3′-trifluoromethylphenyl)-3-(4″-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | |
CN103232360B (zh) | 合成伊伐布雷定及其可药用酸加成盐的方法 | |
US6197969B1 (en) | Process for producing substituted alkylamines or salts thereof | |
KR101625128B1 (ko) | 3,4-디메톡시바이사이클로[4.2.0]옥타-1,3,5-트리엔-7-카보니트릴의 합성 방법, 및 이바브라딘 및 이의 약제학적으로 허용되는 산과의 부가염의 합성에서의 적용 | |
JP2000327603A (ja) | プロピオン酸誘導体の製造方法 | |
KR100424341B1 (ko) | 1-메틸인다졸-3-카르복실산의 제조방법 | |
US5578728A (en) | Process for the preparation of a benzo(a)quinolizione derivative | |
CN111039838B (zh) | 一种3-乙酰巯基-2-甲基丙酸的制备方法 | |
JP3880883B2 (ja) | ピリジン誘導体、その製造方法、及び除草剤中間体としての用途 | |
JP4336913B2 (ja) | アミド誘導体の製造方法 | |
PL182914B1 (pl) | Sposób wytwarzania (-)-N-metylo-N-[4-(4-fenylo-4-acetyloaminopiperydyn-1-ylo)-2-(3,4-dichlorofenylo)butylo]benzamidu | |
US5296603A (en) | 3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid compounds | |
JP4078328B2 (ja) | 2−オキシインドール誘導体の製造法 | |
EP2102216B1 (fr) | Derive fluore de ouinoleine-2(1h)-one, son procede de preparation et son utilisation comme intermediaire de synthese | |
KR20220140555A (ko) | 2-(4-플루오로-3-(트리플루오로메틸)페녹시)부탄산의 분할에 의한 s-베플루부타미드의 제조 | |
KR101226332B1 (ko) | 2-(2-n-부틸-4-히드록시-6-메틸-피리미딘-5-일)-N,N-디메틸아세트아미드의 신규한 제조방법 | |
JP2551375B2 (ja) | 1,5−ベンゾチアゼピン誘導体の製法 | |
KR20190033945A (ko) | 테트라하이드로아이소퀴놀린 유도체의 제조방법 | |
JPH02304066A (ja) | 4―ヒドロキシ―6―ポリフルオロアルキルピリミジンの製造方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: NISSAN CHEMICAL INDUSTRIES LTD. Effective date: 20120329 Owner name: NISSAN CHEMICAL INDUSTRIES LTD. Free format text: FORMER OWNER: SUMITOMO CHEMICAL CO. LTD. Effective date: 20120329 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20120329 Address after: Tokyo, Japan, Japan Patentee after: Nissan Chemical Industries Co., Ltd. Address before: Osaka Co-patentee before: Nissan Chemical Industries Co., Ltd. Patentee before: Sumitomo Chemical Co., Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060104 Termination date: 20150225 |
|
EXPY | Termination of patent right or utility model |