CN1492929A - 肌细胞分化因子Fwa267 - Google Patents

肌细胞分化因子Fwa267 Download PDF

Info

Publication number
CN1492929A
CN1492929A CNA028055098A CN02805509A CN1492929A CN 1492929 A CN1492929 A CN 1492929A CN A028055098 A CNA028055098 A CN A028055098A CN 02805509 A CN02805509 A CN 02805509A CN 1492929 A CN1492929 A CN 1492929A
Authority
CN
China
Prior art keywords
polypeptide
polynucleotides
fwa267
dna
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028055098A
Other languages
English (en)
Inventor
̫
惠汝太
陈敬洲
刘宝华
刘玉清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fuwai Hospital of CAMS and PUMC
Original Assignee
Fuwai Hospital of CAMS and PUMC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuwai Hospital of CAMS and PUMC filed Critical Fuwai Hospital of CAMS and PUMC
Publication of CN1492929A publication Critical patent/CN1492929A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

本发明公开了肌细胞分化因子Fwa267多肽和编码这种多肽的多核苷酸。本发明也公开了用重组技术生产Fwa267多肽的方法和针对这种多肽的抗体和拮抗剂。本发明还公开了含有Fwa267多肽的药物组合物以及Fwa267在治疗心血管增生性疾病、抑制肿瘤形成等方面的用途。本发明还提供了通过检测样品中Fwa267核酸序列中的突变，或者Fwa267多肽含量及Fwa267基因产物自身抗体水平的改变而进行诊断和测定的方法。本发明的肌细胞分化因子是人类来源的。

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CNA028055098A 2001-02-28 2002-02-28 肌细胞分化因子Fwa267 Pending CN1492929A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN01109260A CN1373216A (zh) 2001-02-28 2001-02-28 肌细胞增殖抑制因子Fwa267
CN01109260.2 2001-02-28

Publications (1)

Publication Number Publication Date
CN1492929A true CN1492929A (zh) 2004-04-28

Family

ID=4657824

Family Applications (2)

Application Number Title Priority Date Filing Date
CN01109260A Pending CN1373216A (zh) 2001-02-28 2001-02-28 肌细胞增殖抑制因子Fwa267
CNA028055098A Pending CN1492929A (zh) 2001-02-28 2002-02-28 肌细胞分化因子Fwa267

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN01109260A Pending CN1373216A (zh) 2001-02-28 2001-02-28 肌细胞增殖抑制因子Fwa267

Country Status (3)

Country Link
US (1) US20040110683A1 (zh)
CN (2) CN1373216A (zh)
WO (1) WO2002068640A1 (zh)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2173592C (en) * 1993-10-06 2007-09-25 Michael J. P. Lawman Stem cell proliferation factor
US6432673B1 (en) * 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
CN1326973A (zh) * 2000-06-07 2001-12-19 上海博德基因开发有限公司 一种新的多肽——人层粘连蛋白γ3链(LAMC3)69.85和编码这种多肽的多核苷酸

Also Published As

Publication number Publication date
US20040110683A1 (en) 2004-06-10
WO2002068640A1 (fr) 2002-09-06
CN1373216A (zh) 2002-10-09

Similar Documents

Publication Publication Date Title
JP2002521055A (ja) ９８個のヒト分泌タンパク質
JP2002533058A (ja) ９７個のヒト分泌タンパク質
JP2003514541A (ja) １８個のヒト分泌タンパク質
JP2003528587A (ja) ２７個のヒト分泌タンパク質
JP2002501738A (ja) ６７個のヒト分泌タンパク質
JP2003513662A (ja) １５個のヒト分泌タンパク質
JP2002526059A (ja) ３１個のヒト分泌タンパク質
JP2008167759A (ja) ステロイド抵抗性ネフローゼ症候群に関与するｎｐｈｓ２遺伝子、上記遺伝子によりコードされるタンパク質、並びにそれらの診断的及び治療的使用
JP2003524366A (ja) ６４個のヒト分泌タンパク質
JPH11509093A (ja) 乳房特異的遺伝子およびタンパク質
JP2003501026A (ja) 脂質代謝転写因子
JP2002505871A (ja) ３１個のヒト分泌タンパク質
JP2002514925A (ja) １９個のヒト分泌タンパク質
JPH11506920A (ja) 結腸特異的遺伝子およびタンパク質
JP2003514543A (ja) ２３個のヒト分泌タンパク質
JP4476491B2 (ja) 新規膜貫通蛋白質をコードする遺伝子
JP2003521216A (ja) ９０個のヒト分泌タンパク質
JP2003521215A (ja) ８３個のヒト分泌タンパク質
JPH10513044A (ja) ヒト前立腺特異的還元酵素
CN1509332A (zh) 炎性抑制因子Fwa116
CN1492929A (zh) 肌细胞分化因子Fwa267
JP2000509255A (ja) 感覚神経障害と関連した遺伝子ファミリー
JP2002530058A (ja) ３１個のヒト分泌タンパク質
US20030054446A1 (en) Novel retina-specific human proteins C7orf9, C12orf7, MPP4 and F379
JP2003520030A (ja) ２８個のヒト分泌タンパク質

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication