CN1484642A - 兴奋性氨基酸受体拮抗剂 - Google Patents
兴奋性氨基酸受体拮抗剂 Download PDFInfo
- Publication number
- CN1484642A CN1484642A CNA018217508A CN01821750A CN1484642A CN 1484642 A CN1484642 A CN 1484642A CN A018217508 A CNA018217508 A CN A018217508A CN 01821750 A CN01821750 A CN 01821750A CN 1484642 A CN1484642 A CN 1484642A
- Authority
- CN
- China
- Prior art keywords
- compound
- pharmaceutically acceptable
- alkyl
- acceptable salt
- decahydroisoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26001401P | 2001-01-05 | 2001-01-05 | |
| US60/260,014 | 2001-01-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1484642A true CN1484642A (zh) | 2004-03-24 |
Family
ID=22987455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA018217508A Pending CN1484642A (zh) | 2001-01-05 | 2001-12-20 | 兴奋性氨基酸受体拮抗剂 |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1351955A1 (enExample) |
| JP (1) | JP2004520335A (enExample) |
| KR (1) | KR20030066797A (enExample) |
| CN (1) | CN1484642A (enExample) |
| AR (1) | AR035679A1 (enExample) |
| BR (1) | BR0116672A (enExample) |
| CA (1) | CA2431545A1 (enExample) |
| CZ (1) | CZ20031856A3 (enExample) |
| DZ (1) | DZ3460A1 (enExample) |
| EA (1) | EA200300770A1 (enExample) |
| EC (1) | ECSP034682A (enExample) |
| HR (1) | HRP20030544A2 (enExample) |
| HU (1) | HUP0302528A2 (enExample) |
| IL (1) | IL156138A0 (enExample) |
| MX (1) | MXPA03005981A (enExample) |
| NO (1) | NO20032973L (enExample) |
| NZ (1) | NZ525821A (enExample) |
| PE (1) | PE20020792A1 (enExample) |
| PL (1) | PL361934A1 (enExample) |
| SK (1) | SK8242003A3 (enExample) |
| TW (1) | TW591023B (enExample) |
| WO (1) | WO2002053561A1 (enExample) |
| ZA (1) | ZA200304311B (enExample) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284957A (en) * | 1992-09-03 | 1994-02-08 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| CA2319652A1 (en) * | 1998-02-06 | 1999-08-12 | Michael Urquhart | Salts of paroxetine |
| GB9908175D0 (en) * | 1999-04-09 | 1999-06-02 | Lilly Co Eli | Method of treating neurological disorders |
| IL146697A0 (en) * | 1999-07-06 | 2002-07-25 | Lilly Co Eli | SELECTIVE iGluR5 RECEPTOR FOR THE TREATMENT OF MIGRAINE |
-
2001
- 2001-12-20 HU HU0302528A patent/HUP0302528A2/hu unknown
- 2001-12-20 EA EA200300770A patent/EA200300770A1/ru unknown
- 2001-12-20 CZ CZ20031856A patent/CZ20031856A3/cs unknown
- 2001-12-20 DZ DZ013460A patent/DZ3460A1/fr active
- 2001-12-20 WO PCT/US2001/044715 patent/WO2002053561A1/en not_active Ceased
- 2001-12-20 IL IL15613801A patent/IL156138A0/xx unknown
- 2001-12-20 HR HR20030544A patent/HRP20030544A2/hr not_active Application Discontinuation
- 2001-12-20 BR BR0116672-7A patent/BR0116672A/pt not_active IP Right Cessation
- 2001-12-20 CA CA002431545A patent/CA2431545A1/en not_active Abandoned
- 2001-12-20 SK SK824-2003A patent/SK8242003A3/sk unknown
- 2001-12-20 KR KR10-2003-7008977A patent/KR20030066797A/ko not_active Withdrawn
- 2001-12-20 EP EP01995980A patent/EP1351955A1/en not_active Withdrawn
- 2001-12-20 MX MXPA03005981A patent/MXPA03005981A/es unknown
- 2001-12-20 NZ NZ525821A patent/NZ525821A/en unknown
- 2001-12-20 CN CNA018217508A patent/CN1484642A/zh active Pending
- 2001-12-20 PL PL01361934A patent/PL361934A1/xx not_active Application Discontinuation
- 2001-12-20 JP JP2002554680A patent/JP2004520335A/ja active Pending
-
2002
- 2002-01-04 AR ARP020100030A patent/AR035679A1/es not_active Application Discontinuation
- 2002-01-04 TW TW091100071A patent/TW591023B/zh not_active IP Right Cessation
- 2002-01-04 PE PE2002000003A patent/PE20020792A1/es not_active Application Discontinuation
-
2003
- 2003-06-02 ZA ZA200304311A patent/ZA200304311B/en unknown
- 2003-06-27 NO NO20032973A patent/NO20032973L/no not_active Application Discontinuation
- 2003-07-03 EC EC2003004682A patent/ECSP034682A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002053561A1 (en) | 2002-07-11 |
| HRP20030544A2 (en) | 2004-08-31 |
| DZ3460A1 (fr) | 2002-07-11 |
| NO20032973D0 (no) | 2003-06-27 |
| JP2004520335A (ja) | 2004-07-08 |
| IL156138A0 (en) | 2003-12-23 |
| CA2431545A1 (en) | 2002-07-11 |
| TW591023B (en) | 2004-06-11 |
| BR0116672A (pt) | 2003-09-23 |
| CZ20031856A3 (cs) | 2003-09-17 |
| EP1351955A1 (en) | 2003-10-15 |
| AR035679A1 (es) | 2004-06-23 |
| KR20030066797A (ko) | 2003-08-09 |
| ZA200304311B (en) | 2004-09-02 |
| EA200300770A1 (ru) | 2003-10-30 |
| NO20032973L (no) | 2003-06-27 |
| PL361934A1 (en) | 2004-10-18 |
| MXPA03005981A (es) | 2003-09-10 |
| HUP0302528A2 (hu) | 2003-11-28 |
| PE20020792A1 (es) | 2002-09-06 |
| NZ525821A (en) | 2004-07-30 |
| SK8242003A3 (en) | 2004-01-08 |
| ECSP034682A (es) | 2003-08-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1359289A (zh) | 治疗偏头痛的选择性iGluR5受体拮抗剂 | |
| CN1859904A (zh) | 用于治疗阿尔茨海默氏病的苄醚和苄氨基β－分泌酶抑制剂 | |
| CN1287487A (zh) | 氨基苯氧基乙酸衍生物和含有它们的药用组合物 | |
| CN1208347A (zh) | 取代的n－[(氨基亚氨基甲基和氨基甲基)苯基]丙基酰胺 | |
| CN1791576A (zh) | 代谢型谷氨酸受体的苯甲酰胺调节剂 | |
| CN1768055A (zh) | 作为代谢型谷氨酸受体－5调制剂的四环咪唑衍生物 | |
| CN1023010C (zh) | 4-杂五环-4-[n-(苯基)酰氨基]哌啶衍生物的制备方法 | |
| US6362182B1 (en) | Morpholinone and morpholine derivatives and uses thereof | |
| JP2010235623A (ja) | 鎮痛剤としてのデカヒドロイソキノリン−３−カルボン酸のエステルプロドラッグ | |
| CN1285828A (zh) | 被含有一个氮原子的五、六或七元杂环取代的咪唑基烷基 | |
| CN1193014C (zh) | 新的吡咯磺酰胺化合物 | |
| CN1484642A (zh) | 兴奋性氨基酸受体拮抗剂 | |
| US6579886B2 (en) | Selective iglur5 receptor antagonists | |
| JP2008179650A (ja) | 興奮性アミノ酸レセプターアンタゴニストを含有する医薬組成物 | |
| US6953805B2 (en) | Excitatory amino acid receptor antagonists | |
| CN1886370A (zh) | N－酰基－n′－苄基－亚烷基二氨基衍生物 | |
| US6855725B2 (en) | Excitatory amino acid receptor antagonists | |
| US6924294B2 (en) | Excitatory amino acid receptor antagonists | |
| US20040082606A1 (en) | Excitatory amino acid receptor antagonists | |
| EP1351689A2 (en) | Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases | |
| US7205313B2 (en) | Excitatory amino acid receptor antagonists | |
| AU2002227021A1 (en) | Excitatory amino acid receptor antagonists | |
| HK1025317B (en) | Quinoxalinediones | |
| HK1025317A1 (en) | Quinoxalinediones | |
| JP2004520335A5 (enExample) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |