CN1458257A - 一种清洗杀菌的复方露状洗剂及其制备方法 - Google Patents
一种清洗杀菌的复方露状洗剂及其制备方法 Download PDFInfo
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Abstract
Description
试验菌 | 作用不同时间的平均杀灭率及范围(%) | |||
1min | 3min | 5min | 10min | |
第6代大肠杆菌8099 | 22.52(20.32-26.56) | 40.31(37.90-42.18) | 67.29(66.40-68.54) | 90.18(89.91-90.39) |
第6代金黄色葡萄球菌ATCC6538 | 22.31(20.32-25.60) | 39.05(38.16-40.51) | 67.07(66.66-67.91) | 88.61(87.80-89.07) |
第4代绿脓假单胞菌10102 | 32.31(31.25-33.07) | 52.12(51.78-52.63) | 73.95(73.22-74.73) | 93.01(92.23-93.89) |
第7代白色念珠球菌ATCC10231 | 19.48(18.96-19.81) | 33.78(31.81-36.79) | 56.01(54.54-56.89) | 79.72(78.86-80.68) |
第4代淋病奈瑟氏菌29106 | 48.48(45.90-53.03) | 85.45(85.24-85.60) | 92.27(91.94-92.62) | 98.51(98.44-98.55) |
第4代红色毛癣菌01634 | 23.16(21.91-24.17) | 40.72(40.42-41.09) | 62.96(60.27-64.89) | 90.40(90.21-90.68) |
剂量(mg/kgBW) | 性别 | 动物数(只) | 死亡动物数(只) | 死亡率(%) |
6000 | 雌 | 10 | 0 | 0 |
6000 | 雄 | 10 | 0 | 0 |
剂量(mg/kgBw) | 性别 | 动物数(只) | 嗜多染细胞数(个) | 有微核细胞数(个) | 微核率(‰) | PCE/NCE( X±s) |
阴性对照 | 雌雄 | 55 | 5×10005×1000 | 109 | 2.01.8 | 1.12±0.061.11±0.04 |
低剂量(500) | 雌雄 | 55 | 5×10005×1000 | 118 | 2.21.6 | 1.12±0.051.12±0.04 |
中剂量(2000) | 雌雄 | 55 | 5×10005×1000 | 1211 | 2.42.2 | 1.10±0.031.13±0.07 |
高剂量(5000) | 雌雄 | 55 | 5×10005×1000 | 107 | 2.01.4 | 1.10±0.041.14±0.05 |
阳性对照 | 雌雄 | 55 | 5×10005×1000 | 189196 | 37.839.2 | 1.11±0.061.11±0.05 |
染毒天数(天) | 1~4 | 5~8 | 9~12 | 13~16 | 17~20 |
每日染毒剂量(LD50) | 0.10 | 0.15 | 0.22 | 0.34 | 0.50 |
累积染毒总剂量(LD50) | 0.40 | 1.00 | 1.90 | 3.26 | 5.26 |
雌性动物死亡数(只) | 0 | 0 | 0 | 0 | 0 |
雄性动物死亡数(只) | 0 | 0 | 0 | 0 | 0 |
编号 | 体重(kg) | 1小时 | 24小时 | 48小时 | |||||||||
样品 | 对照 | 样品 | 对照 | 样品 | 对照 | ||||||||
红斑 | 水肿 | 红斑 | 水肿 | 红斑 | 水肿 | 红斑 | 水肿 | 红斑 | 水肿 | 红斑 | 水肿 | ||
1 | 2.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2 | 2.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3 | 2.4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
4 | 2.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
积分均值 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
刺激强度 | 无刺激性 | 无刺激性 | 无刺激性 |
编号 | 体重(kg) | 部位 | 刺激反应积分 | |||||||||
6小时 | 24小时 | 48小时 | 4天 | 7天 | ||||||||
样 | 对 | 样 | 对 | 样 | 对 | 样 | 对 | 样 | 对 | |||
1 | 2.5 | 角膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
虹膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
结膜 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
总分 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
2 | 2.5 | 角膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
虹膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
结膜 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
总分 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
3 | 2.4 | 角膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
虹膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
结膜 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
总分 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
4 | 2.5 | 角膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
虹膜 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
结膜 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
总分 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
急性眼刺激积分指数 | 3.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
编号 | 空白对照 | 赋形剂对照 | 受试物组 | ||||||
红斑 | 水肿 | 总分 | 红斑 | 水肿 | 总分 | 红斑 | 水肿 | 总分 | |
1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
积分均值 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
刺激强度 | 无刺激性 | 无刺激性 | 无刺激性 |
Claims (3)
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100333739C (zh) * | 2004-12-05 | 2007-08-29 | 乌尼尔其其格 | 皮肤及生殖器外用消毒蒙药洗剂 |
CN101518569B (zh) * | 2009-03-30 | 2011-10-05 | 士轲兴 | 一种含牛至油的人用消毒液及其生产方法 |
CN103565678A (zh) * | 2013-11-12 | 2014-02-12 | 上海方木精细化工有限公司 | 薄荷洗手液 |
CN106281821A (zh) * | 2015-06-25 | 2017-01-04 | 上海蓝盎电子科技发展有限公司 | 天然植物洗涤产品生产新工艺 |
CN107236616A (zh) * | 2017-06-20 | 2017-10-10 | 李�杰 | 砧板除菌清洗液 |
CN112370394A (zh) * | 2020-12-10 | 2021-02-19 | 青岛格林维尔环保技术有限公司 | 一种含富氢水的免洗手消毒凝胶及其制备方法 |
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2003
- 2003-04-25 CN CN 03123387 patent/CN1202233C/zh not_active Expired - Lifetime
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100333739C (zh) * | 2004-12-05 | 2007-08-29 | 乌尼尔其其格 | 皮肤及生殖器外用消毒蒙药洗剂 |
CN101518569B (zh) * | 2009-03-30 | 2011-10-05 | 士轲兴 | 一种含牛至油的人用消毒液及其生产方法 |
CN103565678A (zh) * | 2013-11-12 | 2014-02-12 | 上海方木精细化工有限公司 | 薄荷洗手液 |
CN103565678B (zh) * | 2013-11-12 | 2016-04-20 | 上海方木精细化工有限公司 | 薄荷洗手液 |
CN106281821A (zh) * | 2015-06-25 | 2017-01-04 | 上海蓝盎电子科技发展有限公司 | 天然植物洗涤产品生产新工艺 |
CN107236616A (zh) * | 2017-06-20 | 2017-10-10 | 李�杰 | 砧板除菌清洗液 |
CN112370394A (zh) * | 2020-12-10 | 2021-02-19 | 青岛格林维尔环保技术有限公司 | 一种含富氢水的免洗手消毒凝胶及其制备方法 |
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