CN1451415A - Medicine for treating acne and preparing process thereof - Google Patents

Medicine for treating acne and preparing process thereof Download PDF

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Publication number
CN1451415A
CN1451415A CN 02117205 CN02117205A CN1451415A CN 1451415 A CN1451415 A CN 1451415A CN 02117205 CN02117205 CN 02117205 CN 02117205 A CN02117205 A CN 02117205A CN 1451415 A CN1451415 A CN 1451415A
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medicine
radix
acne
treatment
rhizoma rhei
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CN1186055C (en
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齐红辉
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  • Medicines Containing Plant Substances (AREA)
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Abstract

A Chinese medicine for treating acne is prepared from 6 Chinese-medicinal materials including scutellaria root, phellodendron bark, bugleweed, trichosanthes root, etc. Its advantages are high curative effect, quickly taking its effect, no toxic by-effect and no recurrence.

Description

A kind of medicine for the treatment of acne and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of acne, specifically be meant with the Chinese herbal medicine Chinese patent medicine of the treatment acne that is feedstock production, the invention still further relates to the preparation method of this medicine.
Background technology
Acne, the traditional Chinese medical science claims acne, is commonly called as the dermatosis that " acne " is a kind of common pilosity.Acne is a kind of pilosebaceous chronic inflammatory disease dermatoses, because of the obstruction of sebaceous gland and pore, cause sebum outflow smooth due to.With acne, pimple, pustule, tuberosity, cyst and cicatrix is its feature, is mainly in men and women person between twenty and fifty's face and chest and back, influences appearance, many patients so back heavy mental burden, influenced live and work.
Acne belongs to the rosacea caused by lung-wind category of motherland's medical science." element is asked the vital QI of the body connecting with natural QI opinion " " sweating is seen wet, is give birth to Cuo." " Yizong Jinjian surgery heart method " think " this card is formed by the lung meridian heat in blood, and every shape such as broomcorn millet are considered to be worth doing in the broken pimple of face nose, and red complexion swells and ache, and breaks out white lead juice ", the pathogenesis that acne is described is a wind and heat in the lung meridian.About the morbidity of acne, the traditional Chinese medical science is thought inhibited pulmonary QI more, the heresy of the sense rheumatism of holding concurrently, so that occlusion of the pores of skin, and interior-heat is flourishing, stagnation of QI-blood, the endocrine disturbance forms.
The western medical treatment acne generally also is that external application or take medicine orally matches, external application can be used acne ointment, tretinoin ointment etc., and oral vitamin C, compound vitamin B, regulate the skin oil and fat secretion with this, strengthen skin resistance, but also oral tetracycline, cimetidine, vitamin B6 are treated acne, but these Therapeutic Method of doctor trained in Western medicine can only play the effect of respite illness, the easily recurrence of treatment back is cured the symptoms, not the disease, and side effect is in various degree arranged.It is desirable that the Chinese traditional treatment acne does not still have at present, medicine efficiently, the problem that also exists index not effect a permanent cure.
Summary of the invention
The object of the present invention is to provide a kind of double effecting a permanent cure of taking stopgap measures, be difficult for multiple method, instant effect, curative effect height, the medicine of the treatment acne that toxic and side effects is low.
Another object of the present invention provides the preparation method of this Retinoids, Retin-A, Renova, Accutane.
Solution of the present invention is at the pathogenic factor of Chinese medicine theory about acne, based on motherland's medical science to pathogenetic understanding of acne and Therapeutic Principle, with reference to modern pharmacology research achievement, from motherland's medical treasure-house, filter out and have clearing away heat and expelling wind, the removing heat from blood dampness removing, the natural edible-plant medicine of clear eliminating the pathogens from the lung heat, soothing liver and strengthening spleen, activating blood circulation to dissipate blood stasis, endocrine regulation.And screen through clinical verification repeatedly and to form.
Medicine of the present invention is made by following component: (consumption is a weight portion)
Radix Scutellariae 15-90 Cortex Phellodendri 15-90 Herba Lycopi 10-60
Radix Angelicae Dahuricae 15-90 Radix Trichosanthis 15-90 Radix Et Rhizoma Rhei 15-90
Preparing pharmaceutical formulation preferred weight of the present invention (part) ratio range is:
Radix Scutellariae 24-60 Cortex Phellodendri 24-60 Herba Lycopi 26-40
Radix Angelicae Dahuricae 24-60 Radix Trichosanthis 24-60 Radix Et Rhizoma Rhei 24-60
The optimum weight of medicine of the present invention (part) proportioning is:
Radix Scutellariae 30 Cortex Phellodendris 30 Herba Lycopi 20
The Radix Angelicae Dahuricae 30 Radix Trichosanthis 30 Radix Et Rhizoma Rhei 30
Medicine of the present invention can be made various dosage forms according to a conventional method, both oral administrations, but external again, wherein preferred externally used paste.
The preparation method of medicine of the present invention is:
The crude drug of respectively distinguishing the flavor of that takes by weighing said ratio is concocted according to a conventional method, mixes, and drying, pulverizing, sieving to obtain fine powder add distilled water then, stir into pasty state, make unguentum and get final product.
In order to show that medicine of the present invention to the remedy of acne effect, systematically selected pimple, pustular, nodositas, the case of the patients with acne of all ages and classes different sexes of cyst utilizes medicine of the present invention to treat, and be 30 days a course of treatment.
Therapeutic Method: with clean of warm water, remove pus shape thing in the acne as much as possible with sterile medical needle before the drug of topical application, soak medicine of the present invention continues 40 minutes at face, washes medicine off and gets final product.
First week every 1 day once repeated above-mentioned Therapeutic Method afterwards once in a week.30 is a course of treatment.But the statistical data of the therapeutic effect reference table 1,2,3 of medicine of the present invention and 4 clinical treatment:
The clinical data statistics of the therapeutic effect of table 1 acne papulosa
The course of disease Age group Sex Cure Produce effects Effectively Invalid Effective percentage
The man The woman
Below 6 months 16-50 ?50 ?99 ?149 ?0 ?0 ?0 ?100%
In 20 years 16-30 ?58 ?93 ?140 ?5 ?2 ?4 ?97%
30-40 ?33 ?60 ?80 ?6 ?4 ?3 ?97%
40-50 ?27 ?48 ?61 ?7 ?2 ?5 ?93%
The clinical data statistics of the therapeutic effect of table 2 acne nodosum
The course of disease Age group Sex Cure Produce effects Effectively Invalid Effective percentage
The man The woman
Below 6 months 16-50 ?38 ?64 ?100 ?2 ?0 ?0 ?100%
In 20 years 16-30 ?33 ?51 ?70 ?5 ?2 ?7 ?92%
30-40 ?29 ?32 ?48 ?5 ?2 ?6 ?90%
40-50 ?24 ?37 ?50 ?3 ?3 ?5 ?92%
More than for treating a course of treatment statistical result of the investigation of the tracking in a year.Criterion of therapeutical effect: cure: pimple, tuberosity disappear fully, and transference cure does not have recurrence in 1 year.
Produce effects: skin lesion disappears more than 80%, and symptom disappears substantially, does not have recurrence in 1 year.
Effectively: skin lesion disappears more than 60%, and symptom is most of to disappear, and does not have recurrence in 1 year.
Invalid: the skin lesion less than 20% that disappears, symptom does not have obvious improvement, or recurrence is as before in 1 year after the drug withdrawal.
The clinical data statistics of the therapeutic effect of table 3 pustular seat skin ulcer
The course of disease Age group Sex Cure Produce effects Effectively Invalid Effective percentage
The man The woman
Below 6 months 16-50 ?50 ?100 ?148 ?2 ?0 ?0 ?100%
In 20 years 16-30 ?30 ?50 ?70 ?2 ?2 ?6 ?93%
30-40 ?39 ?45 ?71 ?4 ?2 ?7 ?92%
40-50 ?25 ?36 ?46 ?7 ?3 ?5 ?92%
The clinical data statistics of the therapeutic effect of table 4 acne cystica
The course of disease Age group Sex Cure Produce effects Effectively Invalid Effective percentage
The man The woman
Below 6 months 16-50 ?32 ?50 ?79 ?3 ?0 ?0 ?100%
In 20 years 16-30 ?30 ?48 ?68 ?3 ?2 ?5 ?94%
30-40 ?22 ?30 ?40 ?6 ?1 ?5 ?90%
40-50 ?29 ?30 ?48 ?5 ?2 ?4 ?93%
More than for treating three courses of treatment the statistical result of the investigation of the tracking in 2 years.Criterion of therapeutical effect: cure: pustule, cyst etc. disappears fully, and transference cure does not have recurrence in 2 years.
Produce effects: skin lesion disappears more than 80%, and symptom disappears substantially, does not have recurrence in 2 years.
Effectively: skin lesion disappears more than 60%, and symptom is most of to disappear, and does not have recurrence in 2 years.
Invalid: the skin lesion less than 20% that disappears, symptom does not have obvious improvement, or recurrence is as before in 2 years after the drug withdrawal.
Can reach more than 90% at the various types of acne effective percentage of treatment by the visible medicine of the present invention of above clinical statistics data, and double the effecting a permanent cure of taking stopgap measures, be difficult for multiple method, instant effect, the curative effect height, toxic and side effects is low.
In order to understand essence of the present invention better, the present invention is described further below in conjunction with the specific embodiment.
The specific embodiment
Take by weighing raw material (kilogram) by following proportioning:
Radix Scutellariae 30 Cortex Phellodendris 30 Herba Lycopi 20
The Radix Angelicae Dahuricae 30 Radix Trichosanthis 30 Radix Et Rhizoma Rhei 30
Manufacture method is as follows:
The crude drug of respectively distinguishing the flavor of that takes by weighing said ratio is concocted according to a conventional method, mixes, and is dry, pulverize, cross 800 mesh sieves and become fine powder, adds then and the distilled water of injection volume than 1: 1, stirs into pasty state, makes unguentum and gets final product.

Claims (6)

1. a medicine for the treatment of acne is characterized in that it is the medicine of being made by the following weight proportion raw material,
Radix Scutellariae 15-90 Cortex Phellodendri 15-90 Herba Lycopi 10-60
Radix Angelicae Dahuricae 15-90 Radix Trichosanthis 15-90 Radix Et Rhizoma Rhei 15-90.
2. the medicine of treatment acne according to claim 1, wherein the weight proportion of each raw material is:
Radix Scutellariae 24-60 Cortex Phellodendri 24-60 Herba Lycopi 26-40
Radix Angelicae Dahuricae 24-60 Radix Trichosanthis 24-60 Radix Et Rhizoma Rhei 24-60.
3. the medicine of treatment acne according to claim 1, wherein the weight proportion of each raw material is:
Radix Scutellariae 30 Cortex Phellodendris 30 Herba Lycopi 20
The Radix Angelicae Dahuricae 30 Radix Trichosanthis 30 Radix Et Rhizoma Rhei 30.
4. according to the medicine of claim 1,2 or 3 described treatment acnes, it is characterized in that said medicament is a said dosage form on any pharmaceutics.
5. the medicine of treatment acne according to claim 4 is characterized in that said medicament is a unguentum.
6. the preparation method of the medicine of treatment acne according to claim 5 is characterized in that the crude drug of respectively distinguishing the flavor of that takes by weighing said ratio concocts according to a conventional method, mixes, drying, pulverizing, sieving to obtain fine powder, add distilled water then, stir into pasty state, make unguentum and get final product.
CNB021172056A 2002-04-16 2002-04-16 Medicine for treating acne and preparing process thereof Expired - Fee Related CN1186055C (en)

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Application Number Priority Date Filing Date Title
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CN1186055C CN1186055C (en) 2005-01-26

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100396302C (en) * 2004-10-14 2008-06-25 任成钧 Acne treating medicine
CN106668343A (en) * 2017-01-13 2017-05-17 深圳市宝安区妇幼保健院 Herbal composition for improving skin acne, and preparation method and application of herbal composition
CN106880681A (en) * 2017-03-18 2017-06-23 泰兴市丽姿生物制品有限公司 A kind of removing acne and freckle beauty treatment Essence
CN107281029A (en) * 2017-06-30 2017-10-24 安徽陛颜祛斑技术研究有限公司 A kind of mask for acne powder

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579607B (en) * 2012-03-15 2013-07-10 高树霞 Chinese medicine composition for treating acne

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100396302C (en) * 2004-10-14 2008-06-25 任成钧 Acne treating medicine
CN106668343A (en) * 2017-01-13 2017-05-17 深圳市宝安区妇幼保健院 Herbal composition for improving skin acne, and preparation method and application of herbal composition
CN106880681A (en) * 2017-03-18 2017-06-23 泰兴市丽姿生物制品有限公司 A kind of removing acne and freckle beauty treatment Essence
CN107281029A (en) * 2017-06-30 2017-10-24 安徽陛颜祛斑技术研究有限公司 A kind of mask for acne powder

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