CN103520566B - Chinese medicinal cream for treating acnes - Google Patents
Chinese medicinal cream for treating acnes Download PDFInfo
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- CN103520566B CN103520566B CN201310445295.9A CN201310445295A CN103520566B CN 103520566 B CN103520566 B CN 103520566B CN 201310445295 A CN201310445295 A CN 201310445295A CN 103520566 B CN103520566 B CN 103520566B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal cream for treating acnes. The Chinese medicinal cream is prepared from Chinese medicinal active ingredients and auxiliary materials, wherein the Chinese medicinal active ingredients are extracted from the following components in parts by weight: 6-14 parts of cortex mori radicis, 3-7 parts of platycodon root, 6-12 parts of rhizoma anemarrhenae, 3-7 parts of licorice, 4-8 parts of coptis root, 12-18 parts of fructus forsythiae, 6-14 parts of cortex phellodendri, 10-25 parts of cassia twig, 6-14 parts of honeysuckle, 10-30 parts of spatholobus stem, 6-14 parts of oldenlandia diffusa, 12-18 parts of lightyellow sophora root, 6-14 parts of self-heal, 6-14 parts of dandelion, 4-8 parts of gypsum, 4-8 parts of purslane, 6-14 parts of giant knotweed, 6-14 parts of semen coicis, 6-10 parts of periostracum cicadae, 7-10 parts of angelica root, 6-12 parts of pearl powder and the like; the auxiliary materials consist of the following components in parts by weight: 15-20 parts of glycerol, 8-12 parts of tween-80, 100-150 parts of Vaseline, 15-20 parts of single fatty acid glyceride, 50-65 parts of lanolin and 115-130 parts of stearyl alcohol. The Chinese medicinal cream is simple and convenient in preparation, wide in medicinal herb resource and low in cost, and can achieve a significant curative effect after being topically applied to acnes.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of dairy cow of Acne treatment.
Background technology
Acne is a kind of multifactorial disease, and the factors such as at present known its morbidity is secreted in a large number with sex hormone level, sebaceous gland, propionibacterium acnes propagation, abnormal cornification of pilosebaceous duct and inflammation are relevant.Conventionally, acne is apt to occur in Adolescent male or women, and indivedual patients also can extend to more than 30 years old.Although acne is the disease that has spontaneous recovery tendency, the cicatrix that acne itself and acne treatment cause not in time can have a strong impact on patient's quality of life, causes patient's stress and financial burden, and therefore the medicine of Acne treatment is the study hotspot of this area.
In the traditional Chinese medical science, acne is called as " acne " or " comedo ".The traditional Chinese medical science thinks, acne majority is eating and drinking without temperance, impairing the spleen and stomach, and lung stomach is hot and suffocating, upper steaming face and causing, it demonstrate,proves mostly empirical.And relevant with patient's mood, if long-term spirit is not relaxed, the heresy of pyretic toxicity is taken advantage of a weak point, visitor, between the flesh natural fibre line of meat, or flees in meridians, so that QI and blood venation is obstructed, stasis of blood suppuration of a specified duration and cause abscess.It is the chronic inflammatory disease dermatoses of hair follicle and sebaceous gland.
At present, be generally to adopt antibiotic medicine for oral administration to treat clinically, taking anti-inflammation as main, but some medicine that contains tetracycline, long-term taking medicine can increase the weight of the burden of liver, kidney, and anemia of pregnant woman is especially had to taboo.Therefore, still need to find the little medicine of good effect, toxic and side effects of Acne treatment.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention is according to theory of Chinese medical science, for the pathogeny of acne, subside a swelling as the rule for the treatment of taking heat-clearing and toxic substances removing, removing heat from blood, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease, provide a kind of and prepared conveniently, medicine source is wide, cost is low, the traditional Chinese medicine emulsifiable paste of evident in efficacy, reliable effect, the Acne treatment that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is as follows:
A kind of dairy cow of Acne treatment, it is characterized in that being made by active ingredient of Chinese herbs and adjuvant, wherein said active ingredient of Chinese herbs is by Cortex Mori 6-14 part, Radix Platycodonis 3-7 part, Rhizoma Anemarrhenae 6-12 part, Radix Glycyrrhizae 3-7 part, Rhizoma Coptidis 4-8, Fructus Forsythiae 12-18 part, Cortex Phellodendri 6-14 part, Ramulus Cinnamomi 10-25 part, Flos Lonicerae 6-14 part, Caulis Spatholobi 10-30 part, Herba Hedyotidis Diffusae 6-14 part, Radix Sophorae Flavescentis 12-18 part, Spica Prunellae 6-14 part, Herba Taraxaci 6-14 part, Gypsum Fibrosum 4-8 part, Herba Portulacae 4-8 part, Rhizoma Polygoni Cuspidati 6-14 part, Semen Coicis 6-14 part, Periostracum Cicadae 6-10 part, Radix Angelicae Dahuricae 7-10 part, the extractions such as Margarita powder 6-12 part obtain, adjuvant is by glycerol 15-20 part, Tween 80 8-12 part, vaseline 100-150 part, monoester acid glyceride 15-20 part, lanoline 50-65 part and stearyl alcohol 115-130 part composition, described part is weight portion.
The dairy cow of Acne treatment of the present invention is prepared by the following method: above-mentioned raw material of Chinese medicine medicine is ground into 40-60 object fine powder, add the water of 3-5 times of volume, at 70-80 DEG C, extract 1-2 hour, filter, filtrate is centrifugal with 1500-3000 rev/min, the clear leaf in upper strata is concentrated into 250-300 milliliter, adds glycerol and Tween 80, makes water for subsequent use; Vaseline, monoester acid glyceride, lanoline and stearyl alcohol are heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
Dairy cow of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected Chinese prescription, and by the adjuvant and the preparation technology that optimize.In Chinese medicine composition of the present invention: Cortex Mori has effect of eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema; Radix Platycodonis has effect of lung qi dispersing, evacuation of pus; The Rhizoma Anemarrhenae has effect of heat clearing away, pathogenic fire purging, relieving restlessness; Radix Glycyrrhizae has effect of heat-clearing and toxic substances removing; Rhizoma Coptidis has effect of heat clearing and damp drying, eliminating fire and detoxication; Fructus Forsythiae has effect of heat-clearing and toxic substances removing; Cortex Phellodendri has effect of heat clearing away, pathogenic fire purging, dampness, removing toxic substances; Ramulus Cinnamomi has effect of expelling cold and relieving exterior syndrome; Flos Lonicerae has effect of removing summer-heat blood poison; Caulis Spatholobi has effect of promoting blood circulation to remove obstruction in the collateral; Herba Hedyotidis Diffusae has effect of heat clearing away, dampness removing, removing toxic substances; Radix Sophorae Flavescentis has effect of heat clearing and damp drying; Spica Prunellae have relieve inflammation or internal heat, effect of eliminating stagnation, detumescence; Herba Taraxaci has effect of dispersing swelling and dissipating binds; Gypsum Fibrosum has effect that heat clearing away blood is lived, restrained granulation promoting; Herba Portulacae has effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory; Rhizoma Polygoni Cuspidati has effect of dampness removing, removing blood stasis with potent drugs; Semen Coicis has effect of clearing away heat and discharging pus; Periostracum Cicadae has effect of loose wind heat extraction; The Radix Angelicae Dahuricae has effect of dampness, detumescence, pain relieving; Margarita powder has effect of whitening, control oil, light speckle.Drug component in Chinese medicine composition of the present invention is through dialectical compatibility, complements each other using, and has synergism, plays altogether effect of clearing away heat and cooling blood, detoxification and sores, strengthening the spleen stomach function regulating, blood circulation promoting and blood stasis dispelling, acne reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the thin compound of the present invention all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, through after the local application of acne place, reaches significant therapeutic effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
A dairy cow for Acne treatment, write out a prescription as follows:
Raw material of Chinese medicine medicine is 7 grams of Cortex Mori, 3 grams of Radix Platycodoniss, 6 grams of the Rhizoma Anemarrhenaes, 4 grams, Radix Glycyrrhizae, Rhizoma Coptidis 4,12 grams of Fructus Forsythiaes, 7 grams of Cortex Phellodendris, 11 grams of Ramulus Cinnamomi, 6 grams of Flos Loniceraes, 10 grams of Caulis Spatholobis, 7 grams of Herba Hedyotidis Diffusaes, 12 grams of Radix Sophorae Flavescentiss, 6 grams of Spica Prunellaes, 7 grams of Herba Taraxacis, 4 grams, Gypsum Fibrosum, 5 grams of Herba Portulacaes, 6 grams of Rhizoma Polygoni Cuspidati, 6 grams of Semen Coiciss, 6 grams of Periostracum Cicadaes, 7 grams of the Radixs Angelicae Dahuricae, 8 grams of Margarita powder; Adjuvant is 120 grams of 15 grams of glycerol, 10 grams of Tween 80s, 120 grams, vaseline, 15 grams of monoester acid glycerides, 55 grams of lanolines and stearyl alcohols;
Preparation method is: above-mentioned raw material of Chinese medicine medicine is ground into 40 object fine powders, adds the water of 3 times of volumes, extract 1.5 hours at 70 DEG C, filter, filtrate is centrifugal with 2000 revs/min, and the clear leaf in upper strata is concentrated into 250 milliliters, add glycerol and Tween 80, make water for subsequent use; Vaseline, monoester acid glyceride, lanoline and stearyl alcohol are heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
Embodiment 2
A dairy cow for Acne treatment, write out a prescription as follows:
Raw material of Chinese medicine medicine is 10 grams of Cortex Mori, 5 grams of Radix Platycodoniss, 8 grams of the Rhizoma Anemarrhenaes, 5 grams, Radix Glycyrrhizae, Rhizoma Coptidis 6,15 grams of Fructus Forsythiaes, 8 grams of Cortex Phellodendris, 15 grams of Ramulus Cinnamomi, 8 grams of Flos Loniceraes, 20 grams of Caulis Spatholobis, 10 grams of Herba Hedyotidis Diffusaes, 15 grams of Radix Sophorae Flavescentiss, 8 grams of Spica Prunellaes, 8 grams of Herba Taraxacis, 8 grams, Gypsum Fibrosum, 6 grams of Herba Portulacaes, 8 grams of Rhizoma Polygoni Cuspidati, 8 grams of Semen Coiciss, 8 grams of Periostracum Cicadaes, 8 grams of the Radixs Angelicae Dahuricae, 8 grams of Margarita powder; Adjuvant is 122 grams of 18 grams of glycerol, 10 grams of Tween 80s, 130 grams, vaseline, 18 grams of monoester acid glycerides, 54 grams of lanolines and stearyl alcohols;
Preparation method is: above-mentioned raw material of Chinese medicine medicine is ground into 60 object fine powders, adds the water of 4 times of volumes, extract 1 hour at 80 DEG C, filter, filtrate is centrifugal with 1500 revs/min, and the clear leaf in upper strata is concentrated into 250 milliliters, adds glycerol and Tween 80, makes water for subsequent use; Vaseline, monoester acid glyceride, lanoline and stearyl alcohol are heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
Embodiment 3
A dairy cow for Acne treatment, write out a prescription as follows:
Raw material of Chinese medicine medicine is 14 grams of Cortex Mori, 6 grams of Radix Platycodoniss, 10 grams of the Rhizoma Anemarrhenaes, 6 grams, Radix Glycyrrhizae, Rhizoma Coptidis 7,18 grams of Fructus Forsythiaes, 13 grams of Cortex Phellodendris, 24 grams of Ramulus Cinnamomi, 12 grams of Flos Loniceraes, 20 grams of Caulis Spatholobis, 12 grams of Herba Hedyotidis Diffusaes, 16 grams of Radix Sophorae Flavescentiss, 12 grams of Spica Prunellaes, 12 grams of Herba Taraxacis, 7 grams, Gypsum Fibrosum, 7 grams of Herba Portulacaes, 12 grams of Rhizoma Polygoni Cuspidati, 12 grams of Semen Coiciss, 8 grams of Periostracum Cicadaes, 8 grams of the Radixs Angelicae Dahuricae, 10 grams of Margarita powder; Adjuvant is 120 grams of 20 grams of glycerol, 10 grams of Tween 80s, 140 grams, vaseline, 20 grams of monoester acid glycerides, 60 grams of lanolines and stearyl alcohols;
Preparation method is: above-mentioned raw material of Chinese medicine medicine is ground into 50 object fine powders, adds the water of 5 times of volumes, extract 2 hours at 80 DEG C, filter, filtrate is centrifugal with 2500 revs/min, and the clear leaf in upper strata is concentrated into 300 milliliters, adds glycerol and Tween 80, makes water for subsequent use; By vaseline, monoester acid glyceride, lanoline and just lipidol be heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
Test example 1
One, test case:
Select 200 routine experimenters, the standard of selection is Western medicine diagnose and differential diagnosis in tcm standard, the age between 18-45, the patients with acne not taking any antibiotic medicine in nearly two weeks and use other medicine for external use wherein, women's 126 examples, male's 74 examples.Adopt randomized, double-blind method, above-mentioned case is divided into treatment group and test group, group result is in table 1.
Table 1: test case grouped table
| ? | Slightly | Moderate | Severe | Add up to |
| Treatment group | 62 | 48 | 26 | 136 |
| Matched group | 35 | 20 | 9 | 64 |
Two, diagnosis basis:
1, slight: face or chest and back, from the beginning of at follicular orifice, present the red pimple of small rice grain size;
2, moderate: face or chest and back have scleroma sample hoary hair acne, blackhead or pustule, and with seborrhea;
3, severe: face or chest and back have scleroma property cyst.
Three, usage and dosage:
Prepare ointment of the present invention by the method for embodiment 2.Rear outer putting on the skin cleaned in affected part by treatment group, and every day three times, each consumption is about 1 gram/cm, uses continuously for three weeks.Contrast is carefully with 10 grams of dress adapalene gels, and every day three times, each consumption is about 1 gram/cm, uses continuously fortnight.During medication, avoid eating anything raw or cold, pungent, stimulate and rotten thing, fry, fire burn and stodgy food should not be eaten more.
Four, criterion of therapeutical effect:
1, cure: skin lesion is disappeared, subjective symptoms disappears;
2, take a turn for the better: subjective symptoms obviously alleviates, and skin lesion disappears more than 30%;
3, do not heal: skin lesion and symptom be the unchanged or less than 30% that disappears all.
Five, therapeutic effect:
Use the result of the test of the treatment group of ointment of the present invention and the matched group of use adapalene gel in table 2.
Table 2: result of the test table
As can be seen from the test results, ointment of the present invention can effectively be treated the acne of all kinds and degree.Although the result for the treatment of group and matched group is more approaching, compared with Western medicine, dairy cow of the present invention has overcome the untoward reaction of Western medicine, can greatly improve patient's compliance, and can take the circumstances into consideration to increase consumption and access times with the state of an illness.
Six, model case:
Case 1:
Patient man, 26 years old, forehead and back spread all over slight comedo.Use after two courses for the treatment of of ointment of the present invention, pox point is red and swollen to disappear; Continue to strengthen 2 courses for the treatment of, it is smooth that skin recovers.
Case 2:
Patient female, 24 years old, forehead cheek had red and swollen acne, has scleroma.Use after three courses for the treatment of of ointment of the present invention, cheek pox point disappears more, and forehead slightly reduces.Continue to use after 1 course for the treatment of, acne no longer increases, and it is listless that original acne becomes, and redness disappears.
Claims (2)
1. the dairy cow of an Acne treatment, it is characterized in that being made by active ingredient of Chinese herbs and adjuvant, wherein said active ingredient of Chinese herbs is by Cortex Mori 6-14 part, Radix Platycodonis 3-7 part, Rhizoma Anemarrhenae 6-12 part, Radix Glycyrrhizae 3-7 part, Rhizoma Coptidis 4-8 part, Fructus Forsythiae 12-18 part, Cortex Phellodendri 6-14 part, Ramulus Cinnamomi 10-25 part, Flos Lonicerae 6-14 part, Caulis Spatholobi 10-30 part, Herba Hedyotidis Diffusae 6-14 part, Radix Sophorae Flavescentis 12-18 part, Spica Prunellae 6-14 part, Herba Taraxaci 6-14 part, Gypsum Fibrosum 4-8 part, Herba Portulacae 4-8 part, Rhizoma Polygoni Cuspidati 6-14 part, Semen Coicis 6-14 part, Periostracum Cicadae 6-10 part, Radix Angelicae Dahuricae 7-10 part, the extraction of Margarita powder 6-12 part obtains, adjuvant is by glycerol 15-20 part, Tween 80 8-12 part, vaseline 100-150 part, monoester acid glyceride 15-20 part, lanoline 50-65 part and stearyl alcohol 115-130 part composition, described part is weight portion,
Its preparation method is: raw material of Chinese medicine medicine is ground into 40-60 object fine powder, adds the water of 3-5 times of volume, at 70-80 DEG C, extract 1-2 hour, filter, filtrate is centrifugal with 1500-3000 rev/min, and the supernatant is concentrated into 250-300 milliliter, add glycerol and Tween 80, make water for subsequent use; Vaseline, monoester acid glyceride, lanoline and stearyl alcohol are heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
2. the preparation method of the dairy cow of Acne treatment as claimed in claim 1, its step mule is: raw material of Chinese medicine medicine is ground into 40-60 object fine powder, add the water of 3-5 times of volume, at 70-80 DEG C, extract 1-2 hour, filter, filtrate is centrifugal with 1500-3000 rev/min, and the supernatant is concentrated into 250-300 milliliter, add glycerol and Tween 80, make water for subsequent use; Vaseline, monoester acid glyceride, lanoline and stearyl alcohol are heated to 70-80 DEG C of fusing, make oil phase for subsequent use; Water is slowly joined in oil phase, stir, to obtain final product.
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| CN105343665A (en) * | 2015-11-25 | 2016-02-24 | 赵世明 | Traditional Chinese medicine composition for acne treatment |
| CN105797000A (en) * | 2016-03-25 | 2016-07-27 | 广西大学 | Preparation method of ointment for removing acne |
| CN106334141A (en) * | 2016-09-13 | 2017-01-18 | 佛山市顺德区宝铜金属科技有限公司 | Traditional Chinese medicine for removing acne and eliminating sores |
| CN108703925A (en) * | 2018-07-18 | 2018-10-26 | 邓家松 | A kind of acne eliminating cream and preparation method thereof containing traditional Chinese medicine ingredients |
| CN109303876A (en) * | 2018-12-17 | 2019-02-05 | 曲沃李时珍医药科技有限公司 | A kind of medical facial cold compress gel and preparation method thereof for treating acne |
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| CN101987181A (en) * | 2009-08-07 | 2011-03-23 | 王晓锐 | Chinese medicine ointment for treating acne |
| CN102188541A (en) * | 2011-04-27 | 2011-09-21 | 葛晓云 | Pure Chinese medicinal preparation for treating acnes |
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