CN104721349A

CN104721349A - Xiao Cuo Ling (acne remover) traditional Chinese medicine composition and preparation method thereof

Info

Publication number: CN104721349A
Application number: CN201510168434.7A
Authority: CN
Inventors: 卫俊斗
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-04-12
Filing date: 2015-04-12
Publication date: 2015-06-24
Anticipated expiration: 2035-04-12
Also published as: CN104721349B

Abstract

The invention relates to Xiao Cuo Ling (acne remover) traditional Chinese medicine composition. The Xiao Cuo Ling traditional Chinese medicine composition comprises oral preparation and external use preparation. The oral preparation comprises, by weight, 80-120 parts of wild chrysanthemum flower, 80-120 parts of cordate houttuynia, 150-250 parts of oldenlandia diffusa, 150-250 parts of dandelion, 250-350 parts of raw astragalus, 50-70 parts of lithospermum, 120-180 parts of fructus forsythiae, 120-180 parts of wine-treated rhubarb, 120-180 parts of red-rooted salvia roots, 250-350 parts of eclipta alba and 150-250 parts of glossy privet fruit. The external use preparation comprises, by weight, 120-180 parts of rhizome kaempferiae, 120-180 parts of sulfur, 120-180 parts of golden cypress and 120-180 parts of borneol. The Xiao Cuo Ling traditional Chinese medicine composition is prepared by special formula and dosage form; various medicines are matched to achieve outstanding synergistic effect and effective rate for treating acnes is up to 97%.

Description

A kind of Xiao Cuo Jie Fu Cream Chinese medicine composition and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, particularly relate to a kind of Xiao Cuo Jie Fu Cream Chinese medicine composition and preparation method thereof.

Background technology

Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, is mainly apt to occur in teenager, to teen-age psychology and social influence very large, but often can naturally alleviate or fully recover after adolescence.Clinical manifestation is to be apt to occur in the pleomorphism skin lesion such as acne, pimple, pustule, tuberosity of face for feature.Modern medicine study is thought, generation and the dietary structure of acne are unreasonable, psychentonia, trace element deficiency, the factors such as heredity are relevant, principal element is that Development in Puberty is ripe, Serum Testosterone Levels increases stimulates sebum secretion to increase, and is difficult to discharge and be gathered in hair follicle, produces papular infringement, sebaceous gland excretion and disturbance of blood circulation are bred to again the infection of antibacterial and are created condition, and secondary hair follicle and perifollicolar are inflamed abscess and tuberosity.

TCM investigation thinks that acne is a kind of hair follicle sebum gland disease mainly betiding facial area and be main manifestations with acne, pimple.Think from traditional Chinese medical science angle, acne main reason is ferritic deficiency of kidney yin, imbalance of YIN and YANG, and fire is excessively prosperous mutually, in addition the dietetic life imbalance day after tomorrow, or disharmony of Chong and Conception Channels, the showing tremendous enthusiasm heat of lung stomach-fire steams women's head-ornaments and arrives, and heat in blood stasis is sent out as acne.The traditional Chinese medical science is called rosacea caused by lung-wind.

The medicine that can be used for Acne treatment is a lot, but is not often that to fall short of the reality be exactly that toxic and side effects is serious.Accutane as popular is the acne medicine ratified by FDA Food and Drug Administration nineteen eighty-two, be also uniquely approved can the medicine of effective Acne treatment, but have the side effect exciting people to be absorbed in depressive state, can cause time serious committing suiside.Tretinoin conventional in addition can make skin heart sharply expand to occur erythema, and epidermal area is plump, irritant, unsuitable prolonged application.

Although the skin care cosmetics on market has some curative effects to some acnes and various mottle on the surface, is all temporary transient, covering effect can only be played, take stopgap measures and do not effect a permanent cure, not have therapeutical effect at all, can not tackle the problem at its root.

Summary of the invention

The object of this invention is to provide a kind of Xiao Cuo Jie Fu Cream Chinese medicine composition and preparation method thereof, Acne treatment Be very effective.

Xiao Cuo Jie Fu Cream Chinese medicine composition of the present invention, comprises Oral preparation and external preparation; Described Oral preparation is made up of the crude drug of following parts by weight: Flos Chrysanthemi Indici 80 ~ 120 parts, Herba Houttuyniae 80 ~ 120 parts, Herba Hedyotidis Diffusae 150 ~ 250 parts, Herba Taraxaci 150 ~ 250 parts, Radix Astragali 250 ~ 350 parts, Radix Arnebiae (Radix Lithospermi) 50 ~ 70 parts, Fructus Forsythiae 120 ~ 180 parts, Radix et Rhizoma Rhei (stir-fried with wine) 120 ~ 180 parts, Radix Salviae Miltiorrhizae 120 ~ 180 parts, Herba Ecliptae 250 ~ 350 parts, Fructus Ligustri Lucidi 150 ~ 250 parts; Described external preparation is made up of the crude drug of following parts by weight: Rhizoma Kaempferiae 120 ~ 180 parts, sulfur 120 ~ 180 parts, Cortex Phellodendri 120 ~ 180 parts, Borneolum Syntheticum 120 ~ 180 parts.

As optimization, this Xiao Cuo Jie Fu Cream Chinese medicine composition, comprises Oral preparation and external preparation; Described Oral preparation is made up of the crude drug of following parts by weight: Flos Chrysanthemi Indici 100 parts, Herba Houttuyniae 100 parts, Herba Hedyotidis Diffusae 200 parts, Herba Taraxaci 200 parts, Radix Astragali 300 parts, Radix Arnebiae (Radix Lithospermi) 60 parts, Fructus Forsythiae 150 parts, Radix et Rhizoma Rhei (stir-fried with wine) 150 parts, Radix Salviae Miltiorrhizae 150 parts, Herba Ecliptae 300 parts, Fructus Ligustri Lucidi 200 parts; Described external preparation is made up of the crude drug of following parts by weight: how 100 parts, sulfur 100 parts, Cortex Phellodendri 100 parts, Borneolum Syntheticum 100 parts.

Prepare the method for this Xiao Cuo Jie Fu Cream Chinese medicine composition, comprise the following steps: mix homogeneously after the Flos Chrysanthemi Indici of described parts by weight, Herba Houttuyniae, Herba Hedyotidis Diffusae, Herba Taraxaci, Radix Astragali, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Radix et Rhizoma Rhei (stir-fried with wine), Radix Salviae Miltiorrhizae, Herba Ecliptae, Fructus Ligustri Lucidi are pulverized, make honeyed pill or capsule; The Rhizoma Kaempferiae of described parts by weight, Cortex Phellodendri are made 180 object powder, and Borneolum Syntheticum, sulfur wear into fine powder mix homogeneously.

In prescription of the present invention: Herba Ecliptae, Fructus Ligustri Lucidi, Cortex Phellodendri nourishing yin and purging fire; Removing toxic substances, Herba Taraxaci, Flos Chrysanthemi Indici, Herba Houttuyniae, Fructus Forsythiae, Herba Hedyotidis Diffusae lung-heat clearing and detoxification, eliminating stagnation disappears Cuo; Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, blood circulation promoting and dispersing pathogen accumulation, removing heat by catharsis expells the pathogenic heat; The removing toxic substances of Radix Astragali QI invigorating, eliminating the toxic material out by tonification; It is with nourishing yin and purging fire that full side forms, the meaning of detoxicating and resolving stagnation of pathogens.

The present invention adopts special formulation, special form, is prepared from; Qingfei Liangxue, YIN nourishing eliminating stagnation, all medicine compatibilities, synergistic action effect is very outstanding, is used for the treatment of acne effective percentage up to 97%.

Pertinent clinical data is as follows.Physical data: patients with acne 356 example, man 201 example, female 155 example.Be divided into two groups immediately, often organize 178 examples.Two groups in sex, the age, roughly similar in the course of disease, through statistical procedures, difference there are no significant meaning (P > 0.05).

Diagnostic criteria: in " the Chinese medical disease Standardization of diagnosis and curative effect " issued according to State Administration of Traditional Chinese Medicine 1994 acne diagnostic criteria: 1) from the beginning of the red papules presenting small rice grain size at follicular orifice, purulent core can be developed into, after this can form scleroma sample white acne or blackhead, several cases can form scleroma property cyst; 2) be mainly in the face of adolescence men and women, chest and back, often have seborrhea; 3) how by eating and drinking without temperance, surfeit delicious food savoury, or sense exopathogen etc. brings out; 4) women is many with menoxenia; 5) course of disease repeatedly, in chronic process, can form cicatrix.

Exclusion standard: 1) age person more than 35 years old; 2) pregnancy women; 3) occupational acne; 4) severe cardiac, liver, renal damage and disease of hematopoietic system person is had.

Therapeutic Method: treatment group adopts capsule in the embodiment of the present invention 1, every day 3 times, each 4, and external preparation in the external embodiment of the present invention 1; Take one month continuously.The PAIDU YANGYAN JIAONANG of the oral interwined dragon sea of clouds of matched group, every day 2 times, each 4 one month is a course for the treatment of.

Criterion of therapeutical effect: according to the efficacy assessment standard of acne in " Chinese medical disease Standardization of diagnosis and curative effect ", cure: skin lesion disappears, subjective symptoms disappears; Take a turn for the better: subjective symptoms obviously alleviates, and skin lesion disappears more than 30%; Do not heal: skin lesion and symptom unchanged or disappear less than 30%.Treatment comparative result refers to table 1.

Detailed description of the invention

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.

Embodiment 1, get Flos Chrysanthemi Indici 100 grams, Herba Houttuyniae 100 grams, Herba Hedyotidis Diffusae 200 grams, Herba Taraxaci 200 grams, Radix Astragali 300 grams, Radix Arnebiae (Radix Lithospermi) 60 grams, Fructus Forsythiae 150 grams, Radix et Rhizoma Rhei (stir-fried with wine) 150 grams, Radix Salviae Miltiorrhizae 150 grams, Herba Ecliptae 300 grams, the rear mix homogeneously of Fructus Ligustri Lucidi 200 grams pulverizing, according to 0.58 gram one, in incapsulating.Every day 3 times, each 4.

Get Rhizoma Kaempferiae 100 grams, Cortex Phellodendri 100 restrains into 180 object powder, get Borneolum Syntheticum 100 grams, sulfur 100 grams wears into fine powder mix homogeneously; Affected part is spread on, every day 3 times as medicine for external use.

Embodiment 2, get Flos Chrysanthemi Indici 80 grams, Herba Houttuyniae 80 grams, Herba Hedyotidis Diffusae 150 grams, Herba Taraxaci 150 grams, Radix Astragali 250 grams, Radix Arnebiae (Radix Lithospermi) 50 grams, Fructus Forsythiae 120 grams, Radix et Rhizoma Rhei (stir-fried with wine) 120 grams, Radix Salviae Miltiorrhizae 120 grams, Herba Ecliptae 250 grams, the rear mix homogeneously of Fructus Ligustri Lucidi 150 grams pulverizing, according to 0.58 gram one, in incapsulating.Every day 3 times, each 4.

Embodiment 3, get Flos Chrysanthemi Indici 120 grams, Herba Houttuyniae 120 grams, Herba Hedyotidis Diffusae 250 grams, Herba Taraxaci 250 grams, Radix Astragali 350 grams, Radix Arnebiae (Radix Lithospermi) 70 grams, Fructus Forsythiae 180 grams, Radix et Rhizoma Rhei (stir-fried with wine) 180 grams, Radix Salviae Miltiorrhizae 180 grams, Herba Ecliptae 350 grams, the rear mix homogeneously of Fructus Ligustri Lucidi 250 grams pulverizing, according to 0.58 gram one, in incapsulating.Every day 3 times, each 4.

Claims

1. an Xiao Cuo Jie Fu Cream Chinese medicine composition, is characterized in that comprising Oral preparation and external preparation; Described Oral preparation is made up of the crude drug of following parts by weight: Flos Chrysanthemi Indici 80 ~ 120 parts, Herba Houttuyniae 80 ~ 120 parts, Herba Hedyotidis Diffusae 150 ~ 250 parts, Herba Taraxaci 150 ~ 250 parts, Radix Astragali 250 ~ 350 parts, Radix Arnebiae (Radix Lithospermi) 50 ~ 70 parts, Fructus Forsythiae 120 ~ 180 parts, Radix et Rhizoma Rhei (stir-fried with wine) 120 ~ 180 parts, Radix Salviae Miltiorrhizae 120 ~ 180 parts, Herba Ecliptae 250 ~ 350 parts, Fructus Ligustri Lucidi 150 ~ 250 parts; Described external preparation is made up of the crude drug of following parts by weight: Rhizoma Kaempferiae 120 ~ 180 parts, sulfur 120 ~ 180 parts, Cortex Phellodendri 120 ~ 180 parts, Borneolum Syntheticum 120 ~ 180 parts.

2. Xiao Cuo Jie Fu Cream Chinese medicine composition according to claim 1, is characterized in that comprising Oral preparation and external preparation; Described Oral preparation is made up of the crude drug of following parts by weight: Flos Chrysanthemi Indici 100 parts, Herba Houttuyniae 100 parts, Herba Hedyotidis Diffusae 200 parts, Herba Taraxaci 200 parts, Radix Astragali 300 parts, Radix Arnebiae (Radix Lithospermi) 60 parts, Fructus Forsythiae 150 parts, Radix et Rhizoma Rhei (stir-fried with wine) 150 parts, Radix Salviae Miltiorrhizae 150 parts, Herba Ecliptae 300 parts, Fructus Ligustri Lucidi 200 parts; Described external preparation is made up of the crude drug of following parts by weight: Rhizoma Kaempferiae 100 parts, sulfur 100 parts, Cortex Phellodendri 100 parts, Borneolum Syntheticum 100 parts.

3. prepare the method for Xiao Cuo Jie Fu Cream Chinese medicine composition described in claim 1 for one kind, it is characterized in that: mix homogeneously after the Flos Chrysanthemi Indici of described parts by weight, Herba Houttuyniae, Herba Hedyotidis Diffusae, Herba Taraxaci, Radix Astragali, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Radix et Rhizoma Rhei (stir-fried with wine), Radix Salviae Miltiorrhizae, Herba Ecliptae, Fructus Ligustri Lucidi are pulverized, make honeyed pill or capsule; The Rhizoma Kaempferiae of described parts by weight, Cortex Phellodendri are made 180 object powder, and Borneolum Syntheticum, sulfur wear into fine powder mix homogeneously.