CN103919966A

CN103919966A - Medicament for treating acne

Info

Publication number: CN103919966A
Application number: CN201410129555.6A
Authority: CN
Inventors: 王科先; 王欣英; 丁见
Original assignee: Individual
Current assignee: Wang Xinying
Priority date: 2014-04-02
Filing date: 2014-04-02
Publication date: 2014-07-16
Anticipated expiration: 2034-04-02
Also published as: CN103919966B

Abstract

The invention discloses a medicament for treating acne. The medicament is prepared from the following raw traditional Chinese medicinal materials in parts by weight: 20 parts of rhizoma smilacis glabrae, 10 parts of rhizoma bolbostemmae, 10 parts of ligusticum wallichii, 10 parts of prepared rhizoma cyperi, 10 parts of moutan bark, 10 parts of cicada slough, 10 parts of dandelion, 10 parts of patrinia, 6 parts of raw rheum officinale, 10 parts of schizonepeta, 10 parts of fried peach kernel, 30 parts of red peony root, 10 parts of fructus forsythiae, 10 parts of spina gleditsiae, 10 parts of angelica root and 10 parts of chrysanthemum. The raw medicinal materials are compatible by syndrome differentiation to play the effects of clearing heat and cooling blood, dispelling wind, removing toxicity and eliminating dampness, and have a remarkable treatment effect on a patient with acne.

Description

A kind of medicine of Acne treatment

Technical field

The present invention relates to a kind of Chinese medicine composition of Acne treatment.

Background technology

Acne, is called again acne, is a kind of and gonadal Function lack of proper care relevant hair follicle, sebaceous gland chronic inflammatory disease dermatoses, is mainly in face, breast and the back of youth of both sexes, often with seborrhea.Along with the variation of growth in the living standard, dietary structure and increasing the weight of of environmental pollution, this sick sickness rate is higher, and impact beauty treatment, therefore more and more cause people's attention.Although doctor trained in Western medicine has a lot of medicines at present, effect is not very desirable.

Summary of the invention

The object of the present invention is to provide a kind of medicine of Acne treatment.

The technology used in the present invention solution is:

A medicine for Acne treatment, it is to be made by the raw material of Chinese medicine of following weight portion proportioning: 20 parts of Rhizoma Smilacis Glabraes, 10 parts of Rhizoma Bolbostematiss, 10 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Cyperi (processed), 10 parts of Cortex Moutans, 10 parts of Periostracum Cicadaes, 10 parts of Herba Taraxacis, 10 parts of Herba Patriniae, 6 parts of Radix Et Rhizoma Rhei, 10 parts of Herba Schizonepetae, 10 parts of Semen Persicae (parched)s, 30 parts of Radix Paeoniae Rubra, 10 parts of Fructus Forsythiaes, 10 parts of Spina Gleditsiaes, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Flos Chrysanthemis.

Said medicine can be prepared into decoction, and concrete steps are as follows:

Take above all medicines by above-mentioned weight portion proportioning and mix, add 8 times of weight water, soak 2 hours, heating decocts 1.5 hours, filters to obtain decoction liquor one and residue; Residue adds 8 times of weight water again, and heating decocts 1 hour, filters to obtain decoction liquor two; Merge decoction liquor one and decoction liquor two, obtain decoction.

Pharmacology of the present invention and effect are as follows:

The traditional Chinese medical science thinks that acne is many and pents up stifling face because of lung meridian heat in blood, or because of eating and drinking without temperance, surfeit delicious food savoury, and damp-heat in the spleen and stomach, feels ailment said due to cold or exposure again and falls ill.In each raw material of Chinese medicine that the present invention chooses: Rhizoma Smilacis Glabrae sweet in the mouth, light, flat, return liver, stomach warp, function: heat-clearing and toxic substances removing, dehumidifying; Rhizoma Bolbostematis bitter in the mouth, cool, returns liver heart channel, function: powder detoxifcation, the detumescence of row's carbuncle; Flos Chrysanthemi acrid in the mouth, sweet, bitter, be slightly cold, return liver lung meridian, function: dispelling wind and heat pathogens, heat-clearing and toxic substances removing; Cortex Moutan bitter in the mouth, pungent, be slightly cold, GUIXIN, lung meridian, function: clearing away heat and cooling blood, blood stasis dispelling; Rhizoma Chuanxiong acrid in the mouth temperature, returns liver and gall pericardium channel, function: blood-activating and qi-promoting, wind-expelling pain-stopping; Rhizoma Cyperi (processed) acrid in the mouth, micro-hardship, micro-sweet, return liver spleen tri-jiao channel, function: dispersing the stagnated live-QI to relieve the stagnation of QI, regulate the flow of vital energy in tune; Cold lung, the large intestine channel, function of returning of Periostracum Cicadae sweet in the mouth: dispelling wind and heat pathogens, rash relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Herba Taraxaci bitter in the mouth, sweet, cold, returns liver stomach warp; Function: heat-clearing and toxic substances removing, warming middle-JIAO eliminating stagnation, dampness removing; Herba Patriniae acrid in the mouth, hardship, return liver stomach warp, function: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood stasis dispelling are antipruritic; Radix Et Rhizoma Rhei bitter in the mouth, cold, returns spleen, stomach, large intestine, liver, pericardium channel; Function: heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, removing blood stasis; Herba Schizonepetae acrid in the mouth, tepor, return lung, stomach, large intestine channel; Function: expelling pathogenic wind from the body surface, the rash skin ulcer that disappears; Semen Persicae (parched) bitter in the mouth, sweet, flat, function: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Radix Paeoniae Rubra bitter in the mouth, be slightly cold, return lung, Liver Channel; Function: clearing away heat and cooling blood, dissipating blood stasis are antipruritic; Fructus Forsythiae bitter in the mouth, be slightly cold, return lung, the heart, small intestine meridian, function: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens; Spina Gleditsiae acrid in the mouth temperature, returns lung, large intestine channel, function: detumescence and apocenosis, wind dispelling insecticide; Radix Angelicae Dahuricae acrid in the mouth, temperature, return lung, stomach, large intestine channel, function: the cold expelling that induces sweat, dispeiling pathogenic wind and removing dampness, detumescence and apocenosis, antipruritic.In side, all medicines share, and play altogether clearing away heat and cooling blood, effect of the removing toxic substances dehumidifying of dispeling the wind.Medicine card is harmonious, so the treatment of patients with acne is received to good clinical therapeutic efficacy.

Clinical data:

Choose 2009.05-2013.06 and go to a doctor in Huangdao District, Qingdao of Shandong province hospital of traditional Chinese hospital department of Chinese medicine outpatient service patients with acne 300 examples, be divided at random two groups and treat, wherein matched group 150 examples, treatment group 150 examples; The conventional application of matched group tretinoin, antibiotic, estrogen class, glucocorticoid are treated, and treatment group adds and uses Drug therapy of the present invention on the treatment basis of matched group.

Instructions of taking:

Every day potion, every dose of priority is decocted three times, after the front decoction decocted for twice merges point early, take for twice evening, after the decoction of decocting for the 3rd time cools, in order to external application, fortnight is a course for the treatment of.

Points for attention:

Avoid pungent food, greasy food, should light diet, manual-free extruding is kept away in part.

Criterion of therapeutical effect:

Concrete curative effect is divided following three grades: cure---and acne symptom all disappears; Taking a turn for the better---acne symptom obviously alleviates; Invalid---medication is after two weeks, and acne symptom has no to disappear.

Clinical efficacy

Group number of cases is cured the invalid number of cases effective percentage of number of cases improvement number of cases

Treatment group 150 102 40 8 94.67%

Matched group 150 72 32 46 69.33%

Statistical method has carried out date processing with SPSS10.0 statistical software.Data represent with means standard deviation.Between two groups, relatively adopt t inspection, the relatively employing X 2 test of rate.P < 0.05 has statistical significance for difference.

Result: the treatment group P < 0.05 that compares with matched group, has statistics difference.Cure rate, improvement rate and the total effective rate for the treatment of group be all higher than matched group, illustrates that treatment group adds on the basis for the treatment of of control group that to carry out Acne treatment with medicine of the present invention evident in efficacy, is worth further clinical expansion.

Model case:

Case 1

Zhang, female, 28 years old, the facial acne 1 year of repeatedly showing effect, increased the weight of January and examines, over nearly 1 year after local inhabitation, the premenstrual facial acne that occurs, once external multi-medicament (specifically not quite clear), without positive effect, increase the weight of nearly January.Inscribe and see: face is dispersed in acne, taking lower jaw part and wing of nose both sides as outstanding, obviously red and swollen, top white pus born of the same parents, slightly pruritus of companion's pain, slightly irritated, mouthful slightly dry, defecation is without extremely, red tongue with thin fur is greasy slightly yellow, deep and stringy pulse, chi pulse slightly a little less than.Dialectical: the evil knot of stopping up of damp and hot poison, venation is not smooth.The rule for the treatment of: clearing away heat and cooling blood, the removing toxic substances dehumidifying of dispeling the wind.Side's medicine: medicine of the present invention.Every pair of medicine is decocted three times, divides morning, evening to take after front twice mixing, naturally cool to the suitable rear external application of temperature after decocting for the 3rd time; Advise patient's savoury that avoids pungent food, clear water washes one's face simultaneously, and all cosmetics of stopping using, keep facial cleansing.Take after one week, facial acne redness, pain, pruritus all alleviate; Take continuously after one week, acne disappears substantially again.After three months, follow up a case by regular visits to and have no recurrence.

Wang, man, 22 years old, students, in May, 2013 is to our hospital, whole face acne, be acne nodosum after diagnosing, through patient's readme, in the time of school, in many ways seek medical advice, take medicine, make in all sorts of ways, money has been spent a lot, but DeGrain is bad when fashion, when serious, join together in face, chest, back.The rule for the treatment of: clearing away heat and cooling blood, the removing toxic substances dehumidifying of dispeling the wind.Side's medicine: medicine of the present invention.Every pair of medicine is decocted three times, divides morning, evening to take after front twice mixing, naturally cool to the suitable rear external application of temperature after decocting for the 3rd time; Advise patient's savoury that avoids pungent food, clear water washes one's face simultaneously, keeps facial cleansing.Take after one week, acne redness, pain, pruritus all alleviate; Take continuously after one week, acne disappears substantially again, continues to take one week to consolidate curative effect.After three months, follow up a case by regular visits to and have no recurrence.

Detailed description of the invention

Take each raw material of Chinese medicine by following proportioning:

Rhizoma Smilacis Glabrae 20g, Rhizoma Bolbostematis 10g, Rhizoma Chuanxiong 10g, Rhizoma Cyperi (processed) 10g, Cortex Moutan 10g, Periostracum Cicadae 10g, Herba Taraxaci 10g, Herba Patriniae 10g, Radix Et Rhizoma Rhei 6g, Herba Schizonepetae 10g, Semen Persicae (parched) 10g, Radix Paeoniae Rubra 30g, Fructus Forsythiae 10g, Spina Gleditsiae 10g, Radix Angelicae Dahuricae 10g, Flos Chrysanthemi 10g.

Preparation method is as follows:

All medicines after weighing are above mixed, and meter adds 8 times of water gagings by weight ratio, soaks 2 hours, and heating decocts 1.5 hours, filters to obtain decoction liquor one and residue.Residue adds 8 times of water gagings again, and heating decocts 1 hour, filters to obtain decoction liquor two.Merge decoction liquor one and decoction liquor two, obtain decoction.

Claims

1. a medicine for Acne treatment, is characterized in that it is to be made by the raw material of Chinese medicine of following weight portion proportioning: 20 parts of Rhizoma Smilacis Glabraes, 10 parts of Rhizoma Bolbostematiss, 10 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Cyperi (processed), 10 parts of Cortex Moutans, 10 parts of Periostracum Cicadaes, 10 parts of Herba Taraxacis, 10 parts of Herba Patriniae, 6 parts of Radix Et Rhizoma Rhei, 10 parts of Herba Schizonepetae, 10 parts of Semen Persicae (parched)s, 30 parts of Radix Paeoniae Rubra, 10 parts of Fructus Forsythiaes, 10 parts of Spina Gleditsiaes, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Flos Chrysanthemis.

2. the medicine of a kind of Acne treatment according to claim 1, is characterized in that, described medicament is a kind of decoction, and concrete preparation process is as follows:

Take above all medicines by above-mentioned weight portion proportioning and mix, add 8 times of water gagings, soak 2 hours, heating decocts 1.5 hours, filters to obtain decoction liquor one and residue; Residue adds 8 times of water gagings again, and heating decocts 1 hour, filters to obtain decoction liquor two; Merge decoction liquor one and decoction liquor two, obtain decoction.