CN103656438B - Nursing medicine for spine postoperative cuts - Google Patents
Nursing medicine for spine postoperative cuts Download PDFInfo
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- CN103656438B CN103656438B CN201310749681.7A CN201310749681A CN103656438B CN 103656438 B CN103656438 B CN 103656438B CN 201310749681 A CN201310749681 A CN 201310749681A CN 103656438 B CN103656438 B CN 103656438B
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Abstract
The invention discloses a nursing medicine for spine postoperative cuts, and solves the problem of treatment on uncomfortable postoperative cut feeling. The nursing medicine is characterized in that the nursing medicine is prepared from the following raw material medicine in proportion by weight: unpleasant swallowwort herb, buckeye, pine nodular branch, jasminum grandiflorum, semen litchi, ivy glorybind herb root, platycodon grandiflorum, salangane, alpinia japonica, mustard hard paste powder, magnetite and radix puerariae. Clinical experiments prove that the nursing medicine is used for treating the postoperative cut discomfort, has the characteristics of good treatment effect and higher safety, and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to otch care drug after a kind of spinal operation.
Background technology
Bone surgery, especially spinal operation, its operative incision feature is long incision, and in order to visual area just, the traction force causing otch and surrounding tissue thereof to be subject to is large compared with abdominal incision.Although otch can obtain primary healing, after healing, often occur that the phenomenon that otch does not feel like oneself occurs in a short time.As a multicenter clinical investigation shows, when primary healing, local is without red, swollen, hot, bitterly and ooze out, have when the patient of 32.63% one month after surgery and have obvious operative incision sense of discomfort, show as numbness, pain, paraesthesia and local skin to harden, Proportion of patients when three months after surgery with operative incision sense of discomfort is still 24.67%.
This its reason complexity of unresolved operative incision sense of discomfort is various, when performing the operation on the one hand, and cortex, connective tissue layer, muscle layer, tegumentary nerve has damage in various degree; On the other hand in local soft tissue repair process, due to patient body quality factor, cause interstitial fibers connective tissue (extracellular matrix) hyperplasia degree higher than normal parenchyma cytothesis process, due to this kind of fibrous connective tissue only remedy be local form instead of local parenchyma 26S Proteasome Structure and Function, cause local discomfort and skin hardening.
Still lack the therapeutic scheme for sense of discomfort after this kind of postoperative surgical wound healing at present, clinician is many causes local stagnation of QI-blood to explain according to local operation, and recommend patient's external safflower oil blood circulation promoting and blood stasis dispelling, but exist, so this kind of therapeutic scheme is substantially invalid because this pathogenesis system there is no stagnation of QI-blood.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provides a kind of curative effect certainly and otch care drug after the little spinal operation of side effect.
The technical scheme that the present invention solves its technical problem is: otch care drug after a kind of spinal operation, it is characterized in that being prepared from by the crude drug of following weight proportion: Radix Tylophorae arenicolae 10 ~ 30 parts, Semen Aesculi 6 ~ 12 parts, Lignum Pini Nodi 3 ~ 10 parts, Flos jasmini 6 ~ 12 parts, Semen Litchi 3 ~ 10 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 6 ~ 12 parts, Radix Platycodonis 6 ~ 12 parts, Potiria pectinifera (Mukller et Tro Sehel) 6 ~ 12 parts, Alpinia japonica (Thunb.) Miq. 6 ~ 12 parts, 1 ~ 5 part, emplastra sinapis powder, Magnetitum 3 ~ 10 parts, Radix Puerariae 10 ~ 25 parts.
Chinese medicine of the present invention is prepared from by the raw material of following optimum weight part proportioning: Radix Tylophorae arenicolae 20 parts, Semen Aesculi 10 parts, Lignum Pini Nodi 6 parts, Flos jasmini 10 parts, Semen Litchi 6 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10 parts, Radix Platycodonis 10 parts, Potiria pectinifera (Mukller et Tro Sehel) 10 parts, Alpinia japonica (Thunb.) Miq. 10 parts, 2 parts, emplastra sinapis powder, Magnetitum 6 parts, Radix Puerariae 20 parts.
Wherein said: Radix Tylophorae arenicolae, for the spirit of asclepiadaceae plant bamboo disappears the root of Cynanchuminamoenum (Maxim.) Loes. or aerial parts.Nature and flavor are bitter; Micro-pungent; Property is put down.Return lung meridian.Merit can the kidney invigorating, spleen invigorating, removing toxic substances.
Semen Aesculi is Hippocastanaceae plant Aesculus chinensis Bunge Aesculus chinensis Bge., Radix Aesculi Aesculus chinensis Bge.var.chekiangensis(Hu et Fang) dry mature seed of Fang or Aesculus Aesculus wilsonii Rehd..Nature and flavor are sweet, temperature.Return liver, stomach warp.Merit can regulating the flow of QI to ease the stomach, and stomach and alleviating pain.
Lignum Pini Nodi, for Pinus tabulaeformis tabulaeformis Carr, secondly be Pinus densiflora (short leaf Pinus densiflora) Pinusdensiflora Sieb.et Zucc., Folium seu Strobilus Pini sibiricae Pinus sibirica(Loud.) Mayr., Pinus koraiensis (Korean pine) Pinus koraiensis Sieb.et Zucc., Pinus armandi Franch-P. Komavovii Lavl. (Lignum Pini Nodi, five must pine) Pinus armandiiFranch. and Pinus massoniana Lamb, pinus yunnanensis faranch, Pinus kesiya Royle ex Gordon var. langbianensis (A.Chev) Gaussen etc. Lignum Pini Nodi, or be pinaster sick after the knob that grows.Bitter in the mouth; Warm in nature.Return liver; Kidney channel.Merit can dispeiling pathogenic wind and removing dampness; Channels sootheing and network vessel quickening; Promoting blood circulation and stopping pain.
Flos jasmini is Oleaceae plants Flos jasmini Jasminu, the dry flower of grandiflorum L..Property mildly bitter flavor, property put down.Return Liver Channel.Merit can soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain.
Semen Litchi is the dry mature seed of sapindaceous plant Fructus Litchi Litchichinensis Sonn..Sweet, the micro-hardship of nature and flavor, temperature.Return liver, kidney channel.Merit can promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.
Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) is herb or the root of dicotyledon scammonia section plant DAWANHUA Calystegia hederacea Wall..Property sweet and slightly bitter taste; Flat.Return liver; Kidney channel.Merit can spleen invigorating; Dampness removing; Regulating menstruation.
Radix Platycodonis is the dried roots of Campanulaceae Radix Platycodonis, and merit can expelling phlegm for arresting cough, and has lung qi dispersing, evacuation of pus effect.
Potiria pectinifera (Mukller et Tro Sehel) is Echinodermata Asterinidae Potiria pectinifera (Mukller et Tro Sehel) Asterina pectinifera Miller et Troschel, is used as medicine with all (removing internal organs).Nature and flavor are salty, temperature, nontoxic.Merit can YIN nourishing, tonifying YANG, wind-damp dispelling.
Alpinia japonica (Thunb.) Miq., is Zingiberaceae Alpinia plants Alpinia japonica (Thunb.) Miq. Alpinia japonica Miq., is used as medicine with root stock.Nature and flavor are pungent, warm.Return lung, spleen, Liver Channel.Merit can dispelling wind and removing obstruction in the collateral, regulating QI to relieve pain.
Emplastra sinapis powder is crucifer Caulis et Folium Sinapis albee Sinapis alba L. or mustard Brassica juncea(L.) dry mature seed of Czern.et Coss., remove fatty oil after dry grinds and obtain.Nature and flavor are pungent, temperature.Return lung meridian.Merit can warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.
Magnetitum is oxide-based mineral spinelle race magnetic iron ore, main containing ferroso-ferric oxide (Fe3O4).Nature and flavor are salty, cold.Return liver, the heart, kidney channel.Merit can suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, helping inspiration to relieve asthma.
Radix Puerariae, Radix Puerariae is the root of leguminous plant Pachyrhizua angulatus.Sweet, pungent, flat.Enter spleen, stomach warp.Merit can be induced sweat, rash, and relaxing muscles and tendons promotes the production of body fluid, antidiarrheal.
Composition principle: after spinal surgery, otch does not feel like oneself and refers to when operative incision primary healing, local is without red, swollen, hot, bitterly and ooze out, and patient has obvious operative incision sense of discomfort, show as numbness, pain, paraesthesia and local skin and harden.This kind of its reason complexity of sense of discomfort is various, on the one hand cortex, connective tissue layer, muscle layer after wound, and tegumentary nerve has damage in various degree; On the other hand in local soft tissue repair process, due to patient body quality factor, cause interstitial fibers connective tissue (extracellular matrix) hyperplasia degree higher than normal parenchyma cytothesis process, due to this kind of fibrous connective tissue only remedy be local form instead of local parenchyma 26S Proteasome Structure and Function, cause local discomfort and skin hardening.Still lack the therapeutic scheme for sense of discomfort after this kind of operative incision healing at present, clinician is many causes local stagnation of QI-blood to explain according to local wound, and recommend patient's external safflower oil blood circulation promoting and blood stasis dispelling, but exist, so this kind of therapeutic scheme is substantially invalid because this pathogenesis system there is no stagnation of QI-blood.
Compared with prior art, the present invention has following characteristics:
1, we adopt Radix Tylophorae arenicolae and Semen Aesculi to coordinate for monarch drug: lung and skin phase the exterior and the interior, described Radix Tylophorae arenicolae enters lung meridian, can by adjusting being entangled with of lung network skin, Radix Tylophorae arenicolae decocting liquid can improve the albumen caused by inflammation cyst caused anti-mouse carboxymethyl cellulose and ooze out and leukocyte migration, promotes parenchyma hypertrophy; And Semen Aesculi Total saponin 5mg/kg is applied topically to, in rat Ovum Gallus domesticus album connective tissue stimulation model, can suppress fibrous connective tissue hypertrophy.
2, inventor's clinical empirical summary draws, postoperative surgical otch does not feel like oneself relevant with local channels apoplexy cold-damp after wound, so we adopt Lignum Pini Nodi, Alpinia japonica (Thunb.) Miq., Flos jasmini, Semen Litchi wind-damp dispelling, and the meridian dredging; The reason choosing this three herbal medicine in numerous related drugs is, these three kinds of Drugs are gentle, and non-dispelling the damp pathogen with drugs of bitter in taste and cold in nature, does not have the anxiety of impairment of YIN.And the Ginkgolide Component columbin contained in Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) tuber, there is mate-assist to suppress fibrous connective tissue hypertrophy.
3, spinal column otch multidigit follows row position in bladder meridian, and bladder meridian belongs to table, and the present inventor's clinical experience gained, adds Radix Platycodonis, has priming to enter the effect of urinary bladder channel and channels thereof, contributes to passages through which vital energy circulates unobstructed.
4, postoperative surgical otch discomfort is also relevant with the dry impairment of YIN of local blood, and stirring of wind due to deficiency of YIN and numbness, fiber crops are itched, so we adopt Potiria pectinifera (Mukller et Tro Sehel) YIN nourishing and YANG strengthening wind-damp dispelling, is the product of reinforcement and elimination in combination, without growing greasy anxiety.
5, Semen Sinapis eliminating phlegm eliminating stagnation, postoperative surgical otch discomfort belongs to the operative incision of primary healing, this kind of operative incision acute stage mistake, cold-phlegm residual in meridians is all more obstinate, coordinates Semen Litchi to help tonneau so add Semen Sinapis.Semen Sinapis is containing potassium myronate, potassium myronate meets the effect generation volatile oil of water through myrosase, and main component is allyl isosulfocyanate, has stimulation, be applied to skin, there is warm sensation and make it rubescent, even causing blister, pustule, so adopt emplastra sinapis powder in prescription of the present invention, i.e. gained after mustard flour removing fatty oil, this kind of de-fatty oil method is conventional in the industry, and emplastra sinapis powder can directly be buied from market, sufficient raw.But because the present invention needs in local action more than 3 hours, so coordinate Radix Puerariae, Radix Puerariae contains much starch, can alleviate the skin irritation of Semen Sinapis.
6, Magnetitum is originally the product in important city, but rat local topical, local neutrophil phagocytosis reaction can be made to increase.
7, avoid use to take offence promoting the circulation of blood medicine, reducing local fiber hypertrophy initiating stimulates.
Detailed description of the invention
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, crude drug weight proportion: Radix Tylophorae arenicolae 20 parts, Semen Aesculi 10 parts, Lignum Pini Nodi 6 parts, Flos jasmini 10 parts, Semen Litchi 6 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10 parts, Radix Platycodonis 10 parts, Potiria pectinifera (Mukller et Tro Sehel) 10 parts, Alpinia japonica (Thunb.) Miq. 10 parts, 2 parts, emplastra sinapis powder, Magnetitum 6 parts, Radix Puerariae 20 parts.
The preparation method of embodiment 1 is: Radix Tylophorae arenicolae, Semen Aesculi, Lignum Pini Nodi, Flos jasmini, Semen Litchi, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Radix Platycodonis, Potiria pectinifera (Mukller et Tro Sehel), Alpinia japonica (Thunb.) Miq., emplastra sinapis powder (decocting a drug wrapped), Magnetitum, Radix Puerariae mixing and water adding are decocted, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, be condensed into thick paste, appropriate soak is in healing on operative incision.
Embodiment 2, crude drug weight proportion: Radix Tylophorae arenicolae 10 parts, Semen Aesculi 6 parts, Lignum Pini Nodi 3 parts, Flos jasmini 6 parts, Semen Litchi 3 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 6 parts, Radix Platycodonis 6 parts, Potiria pectinifera (Mukller et Tro Sehel) 6 parts, Alpinia japonica (Thunb.) Miq. 6 parts, 1 part, emplastra sinapis powder, Magnetitum 3 parts, Radix Puerariae 10 parts.
Embodiment 3, crude drug weight proportion: Radix Tylophorae arenicolae 20 parts, Semen Aesculi 10 parts, Lignum Pini Nodi 6 parts, Flos jasmini 10 parts, Semen Litchi 6 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10 parts, Radix Platycodonis 10 parts, Potiria pectinifera (Mukller et Tro Sehel) 10 parts, Alpinia japonica (Thunb.) Miq. 10 parts, 2 parts, emplastra sinapis powder, Magnetitum 6 parts, Radix Puerariae 20 parts.
Embodiment 4, crude drug weight proportion: Radix Tylophorae arenicolae 30 parts, Semen Aesculi 12 parts, Lignum Pini Nodi 10 parts, Flos jasmini 12 parts, Semen Litchi 10 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 12 parts, Radix Platycodonis 12 parts, Potiria pectinifera (Mukller et Tro Sehel) 12 parts, Alpinia japonica (Thunb.) Miq. 12 parts, 5 parts, emplastra sinapis powder, Magnetitum 10 parts, Radix Puerariae 25 parts.
The Chinese medicine of embodiment 2 ~ 4 can be prepared from by following method:
(1) Semen Aesculi, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Flos jasmini, Lignum Pini Nodi, Semen Litchi coarse powder are extracted volatile oil with vapor distillation respectively, and mixing for standby use after collecting;
(2) emplastra sinapis powder, Magnetitum, Radix Puerariae are pulverized 150 mesh sieves respectively, and become fine powder for subsequent use;
(3) Radix Tylophorae arenicolae, Radix Platycodonis, Alpinia japonica (Thunb.) Miq., Potiria pectinifera (Mukller et Tro Sehel) mixing add 10 times of water yields, decoct with water 2 times, each 1 hour, collecting decoction, leave standstill; Then in decocting liquid, add the ethanol of 95% of 3 ~ 4 times of medicinal liquids, leave standstill 15 minutes, then with 3000rpm/min centrifugal 20 minutes, get precipitation, spraying dry, draw just material;
(4) sprayed into by gained volatile oil in step 1 during step 3 gained just expects, add gained fine powder mixing in step 2, cross 60 mesh sieves, sterilizing, subpackage form.
During use, dress the operative incision place after healing with warm water.
The efficient combination of said medicine, coordinates mutually, effectively reach the object that treatment postoperative wound does not feel like oneself, and side effect is less.The above results is clinical data sufficient proof, and interrelated data is as follows.
1 object and method
1.1 object
1.1.1 case selection: in January, 2012 ~ 2013 spinal surgery in year August, postoperative primary healing patient, uncomfortable 60 examples of the former operative incision of main suit, the discomfort of main suit comprises local pain, fiber crops, itches, referred pain, formication, companion or do not accompany operative incision surrounding tissue to harden.Be divided into matched group 20 example, thick paste group 18 example and dress group 22 example.Compare in sex, age, Operative category, operative incision length before three groups of patient treatments, no significant difference (P>0.05), has comparability.
1.1.2 inclusive criteria is: 1. spinal surgery is postoperative without other post-operative complication; 2. spinal surgery postoperative surgical otch primary healing; 3. in postoperative three months of spinal surgery; Deep seated infections without red and swollen heat pain, and is got rid of in operative incision local; 4. non-diabetic and mental sickness medical history.
1.2 method
1.2.1 Therapeutic Method: matched group safflower oil local is embrocated, 2 times/d.Thick paste group with the appropriate soak in gained thick paste local in the embodiment of the present invention 1 in healing on operative incision, 2 times/d.Dressing group dresses in healing on operative incision with the appropriate warm water in gained medicated powder local in the embodiment of the present invention 2,2 times/d.3 groups of treatments were all 1 course for the treatment of with 14 days, added up curative effect after the course for the treatment of.
1.2.2 criterion of therapeutical effect: recovery from illness: clinical symptoms, sign disappear; Effective: clinical symptoms, sign turn for the better by and large, and no longer affect life; Effective: clinical symptoms, sign alleviate, but still can affect sleep or life; Invalid: clinical symptoms, sign are unchanged.
1.2.3 statistical analysis: SPSS13.0 carries out statistical analysis.Measurement data t checks, enumeration data χ
2inspection.
2 results
2.1 3 groups of Comprehensive Clinical comparitive study: thick paste group organizes cure rate and matched group difference extremely obviously (thick paste group χ with dressing
2=9.89, P<0.05; Dress group χ
2=8.87, P<0.05), thick paste group organizes total effective rate apparently higher than matched group (thick paste group χ with dressing
2=4.94, P<0.05; Dress group χ
2=4.17, P<0.05), see the following form.
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Total effective rate |
| Matched group | 20 | 1(5.00%) | 6(30.00%) | 6(30.00%) | 7(35.00%) | 65.00% |
| Thick paste group | 18 | 9(50.00%) | 6(33.33%) | 2(11.11%) | 1(5.56%) | 94.44% |
| Dress group | 22 | 10(45.45%) | 6(27.27%) | 4(18.18%) | 2(9.09%) | 90.91% |
2.2 3 groups of adverse reactions of patients incidence rates: three groups all do not occur obvious adverse reaction.
3. conclusion
This result of study shows, and uses thick paste group of the present invention and dresses group cure rate and total effective rate apparently higher than matched group, illustrates the present invention healed after iatrotechnics operative incision do not feel like oneself in have untoward reaction comparatively gently, the higher advantage of safety.
Claims (2)
1. an otch care drug after spinal operation, is characterized in that being prepared from by the crude drug of following weight proportion: Radix Tylophorae arenicolae 10 ~ 30 parts, Semen Aesculi 6 ~ 12 parts, Lignum Pini Nodi 3 ~ 10 parts, Flos jasmini 6 ~ 12 parts, Semen Litchi 3 ~ 10 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 6 ~ 12 parts, Radix Platycodonis 6 ~ 12 parts, Potiria pectinifera (Mukller et Tro Sehel) 6 ~ 12 parts, Alpinia japonica (Thunb.) Miq. 6 ~ 12 parts, 1 ~ 5 part, emplastra sinapis powder, Magnetitum 3 ~ 10 parts, Radix Puerariae 10 ~ 25 parts; Its preparation method is: Radix Tylophorae arenicolae, Semen Aesculi, Lignum Pini Nodi, Flos jasmini, Semen Litchi, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Radix Platycodonis, Potiria pectinifera (Mukller et Tro Sehel), Alpinia japonica (Thunb.) Miq., emplastra sinapis powder, Magnetitum, Radix Puerariae mixing and water adding are decocted, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, be condensed into thick paste, wherein said emplastra sinapis powder is taked to decoct a drug wrapped.
2. otch care drug after a kind of spinal operation according to claim 1, is characterized in that being prepared from by the crude drug of following weight proportion: Radix Tylophorae arenicolae 20 parts, Semen Aesculi 10 parts, Lignum Pini Nodi 6 parts, Flos jasmini 10 parts, Semen Litchi 6 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 10 parts, Radix Platycodonis 10 parts, Potiria pectinifera (Mukller et Tro Sehel) 10 parts, Alpinia japonica (Thunb.) Miq. 10 parts, 2 parts, emplastra sinapis powder, Magnetitum 6 parts, Radix Puerariae 20 parts.
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|---|---|---|---|
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102441044A (en) * | 2011-12-22 | 2012-05-09 | 许从玉 | Care solution for wound cleaning |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN103405559A (en) * | 2013-08-30 | 2013-11-27 | 封秀花 | Clinical wound nursing medicine |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102441044A (en) * | 2011-12-22 | 2012-05-09 | 许从玉 | Care solution for wound cleaning |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN103405559A (en) * | 2013-08-30 | 2013-11-27 | 封秀花 | Clinical wound nursing medicine |
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