CN103656438A - Nursing medicine for spine postoperative cuts - Google Patents
Nursing medicine for spine postoperative cuts Download PDFInfo
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- CN103656438A CN103656438A CN201310749681.7A CN201310749681A CN103656438A CN 103656438 A CN103656438 A CN 103656438A CN 201310749681 A CN201310749681 A CN 201310749681A CN 103656438 A CN103656438 A CN 103656438A
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Abstract
The invention discloses a nursing medicine for spine postoperative cuts, and solves the problem of treatment on uncomfortable postoperative cut feeling. The nursing medicine is characterized in that the nursing medicine is prepared from the following raw material medicine in proportion by weight: unpleasant swallowwort herb, buckeye, pine nodular branch, jasminum grandiflorum, semen litchi, ivy glorybind herb root, platycodon grandiflorum, salangane, alpinia japonica, mustard hard paste powder, magnetite and radix puerariae. Clinical experiments prove that the nursing medicine is used for treating the postoperative cut discomfort, has the characteristics of good treatment effect and higher safety, and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to otch care drug after a kind of spinal operation.
Background technology
Bone surgery, especially spinal operation, its operative incision feature is long incision, and for visual area just, the traction force that causes otch and surrounding tissue thereof to be subject to is large compared with abdominal incision.Although otch can obtain primary healing, after healing, often occur in a short time that the phenomenon that otch does not feel like oneself occurs.As a multicenter clinical investigation shows, the in the situation that of primary healing, local without red, swollen, hot, bitterly and ooze out, there is 32.63% patient in the time of one month after surgery, to have obvious operative incision sense of discomfort, show as numbness, pain, paraesthesia and local skin and harden, the Proportion of patients in the time of three months after surgery with operative incision sense of discomfort is still 24.67%.
This its reason complexity of delay operative incision sense of discomfort is various, while performing the operation on the one hand, and cortex, connective tissue layer, flesh layer, tegumentary nerve has damage in various degree; On the other hand in local soft tissue repair process, due to patient body quality factor, cause interstitial fibers connective tissue (extracellular matrix) hyperplasia degree higher than normal parenchyma cytothesis process, what only remedy due to this kind of fibrous connective tissue is local form rather than the 26S Proteasome Structure and Function of local parenchyma, causes local discomfort and skin hardening.
Still lack at present the therapeutic scheme for sense of discomfort after this kind of postoperative operative incision healing, clinician is many causes local stagnation of QI-blood to explain according to local operation, and recommend patient's external safflower oil blood circulation promoting and blood stasis dispelling, but because there is no stagnation of QI-blood, this pathogenesis system exists, so this kind of therapeutic scheme is substantially invalid.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provide a kind of curative effect certainly and spinal operation that side effect is little after otch care drug.
The technical scheme that the present invention solves its technical problem is: otch care drug after a kind of spinal operation, is characterized in that being prepared from by the crude drug of following weight proportion: 10～30 parts of Radix Tylophorae arenicolaes, 6～12 parts of Semen Aesculies, 3～10 parts of Lignum Pini Nodis, 6～12 parts of Flos jasmini, 3～10 parts of Semen Litchis, 6～12 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 6～12 parts of Radix Platycodoniss, 6～12 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 6～12 parts of Alpinia japonica (Thunb.) Miq.s, 1～5 part, emplastra sinapis powder, 3～10 parts of Magnetitums, 10～25 parts of Radix Puerariaes.
Chinese medicine of the present invention is that the raw material by following optimum weight part proportioning is prepared from: 20 parts of Radix Tylophorae arenicolaes, 10 parts of Semen Aesculies, 6 parts of Lignum Pini Nodis, 10 parts of Flos jasmini, 6 parts of Semen Litchis, 10 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 10 parts of Radix Platycodoniss, 10 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 10 parts of Alpinia japonica (Thunb.) Miq.s, 2 parts, emplastra sinapis powder, 6 parts of Magnetitums, 20 parts of Radix Puerariaes.
Wherein said: Radix Tylophorae arenicolae is the spirit of asclepiadaceae plant bamboo disappear root or the aerial parts of Cynanchum inamoenum (Maxim.) Loes..Nature and flavor are bitter; Micro-pungent; Property is put down.Return lung meridian.Merit can the kidney invigorating, spleen invigorating, removing toxic substances.
Semen Aesculi is Hippocastanaceae plant Aesculus chinensis Bunge Aesculus chinensis Bge., Radix Aesculi Aesculus chinensis Bge.var.chekiangensis(Hu et Fang) dry mature seed of Fang or Aesculus Aesculus wilsonii Rehd..Nature and flavor are sweet, temperature.Return liver, stomach warp.Merit can regulating the flow of QI to ease the stomach, and stomach and alleviating pain.
Lignum Pini Nodi, for Pinus tabulaeformis tabulaeformis Carr, secondly be Pinus densiflora (short leaf Pinus densiflora) Pinus densiflora Sieb.et Zucc., Folium seu Strobilus Pini sibiricae Pinus sibirica(Loud.) Lignum Pini Nodis of Mayr., Pinus koraiensis (Korean pine) Pinus koraiensis Sieb.et Zucc., Pinus armandi Franch-P. Komavovii Lavl. (Lignum Pini Nodi, five must pine) Pinus armandii Franch. and Pinus massoniana Lamb, pinus yunnanensis faranch, Pinus kesiya Royle ex Gordon var. langbianensis (A.Chev) Gaussen etc., or be the knob that pinaster grows after sick.Bitter in the mouth; Warm in nature.Return liver; Kidney channel.Merit can dispeiling pathogenic wind and removing dampness; Channels sootheing and network vessel quickening; Promoting blood circulation and stopping pain.
Flos jasmini is Oleaceae plants Flos jasmini Jasminu, the dry flower of grandiflorum L..Property mildly bitter flavor, property is flat.Return Liver Channel.Merit can soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain.
Semen Litchi is the dry mature seed of sapindaceous plant Fructus Litchi Litchichinensis Sonn..Sweet, the micro-hardship of nature and flavor, temperature.Return liver, kidney channel.Merit can promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.
Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) is herb or the root of the plant DAWANHUA Calystegia hederacea Wall. of dicotyledon scammonia section.Property sweet and slightly bitter taste; Flat.Return liver; Kidney channel.Merit can spleen invigorating; Dampness removing; Regulating menstruation.
Radix Platycodonis, is the dried roots of Campanulaceae Radix Platycodonis, and merit can expelling phlegm for arresting cough, and has lung qi dispersing, evacuation of pus effect.
Potiria pectinifera (Mukller et Tro Sehel), is Echinodermata Asterinidae Potiria pectinifera (Mukller et Tro Sehel) Asterina pectinifera Miller et Troschel, with all (removing internal organs), is used as medicine.Nature and flavor are salty, and temperature is nontoxic.Merit can YIN nourishing, tonifying YANG, wind-damp dispelling.
Alpinia japonica (Thunb.) Miq., for Zingiberaceae Alpinia plants Alpinia japonica (Thunb.) Miq. Alpinia japonica Miq., is used as medicine with root stock.Nature and flavor are pungent, warm.Return lung, spleen, Liver Channel.Merit can dispelling wind and removing obstruction in the collateral, regulating QI to relieve pain.
Emplastra sinapis powder is crucifer Caulis et Folium Sinapis albee Sinapis alba L. or mustard Brassica juncea(L.) dry mature seed of Czern.et Coss., after dry grinds, remove fatty oil and obtain.Nature and flavor are pungent, temperature.Return lung meridian.Merit can warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral pain relieving.
Magnetitum, is oxide-based mineral spinelle family magnetic iron ore, main containing ferroso-ferric oxide (Fe3O4).Nature and flavor are salty, cold.Return liver, the heart, kidney channel.Merit can suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, helping inspiration to relieve asthma.
Radix Puerariae, Radix Puerariae is the root of leguminous plant Pachyrhizua angulatus.Sweet, pungent, flat.Enter spleen, stomach warp.Merit can be induced sweat, rash, and relaxing muscles and tendons, promotes the production of body fluid, antidiarrheal.
Composition principle: after spinal surgery, otch does not feel like oneself and refers to the in the situation that of operative incision primary healing, local without red, swollen, hot, bitterly and ooze out, and patient has obvious operative incision sense of discomfort, show as numbness, pain, paraesthesia and local skin and harden.This kind of its reason complexity of sense of discomfort is various, cortex, connective tissue layer, flesh layer after one side wound, and tegumentary nerve has damage in various degree; On the other hand in local soft tissue repair process, due to patient body quality factor, cause interstitial fibers connective tissue (extracellular matrix) hyperplasia degree higher than normal parenchyma cytothesis process, what only remedy due to this kind of fibrous connective tissue is local form rather than the 26S Proteasome Structure and Function of local parenchyma, causes local discomfort and skin hardening.Still lack at present the therapeutic scheme for sense of discomfort after this kind of operative incision healing, clinician is many causes local stagnation of QI-blood to explain according to local wound, and recommend patient's external safflower oil blood circulation promoting and blood stasis dispelling, but because there is no stagnation of QI-blood, this pathogenesis system exists, so this kind of therapeutic scheme is substantially invalid.
Compared with prior art, the present invention has following characteristics:
1, we adopt Radix Tylophorae arenicolae and Semen Aesculi to coordinate for monarch drug: lung and skin phase the exterior and the interior, described Radix Tylophorae arenicolae enters lung meridian, can be by adjusting being entangled with of lung network skin, the albumen that Radix Tylophorae arenicolae decocting liquid can improve due to the inflammation cyst that antagonism mice carboxymethyl cellulose causes oozes out and leukocyte migration, promotes parenchyma hypertrophy; And the total Saponin 5mg/kg of Semen Aesculi is applied topically to, in rat Ovum Gallus domesticus album connective tissue stimulation model, can suppress fibrous connective tissue hypertrophy.
2, inventor's clinical empirical summary draws, it is relevant with local channels apoplexy cold-damp after wound that postoperative operative incision does not feel like oneself, so we adopt Lignum Pini Nodi, Alpinia japonica (Thunb.) Miq., Flos jasmini, Semen Litchi wind-damp dispelling, the meridian dredging; The reason of choosing this three herbal medicine in numerous related drugs is, these three kinds of Drugs are gentle, and non-dispelling the damp pathogen with drugs of bitter in taste and cold in nature does not have the anxiety of impairment of YIN.And the Ginkgolide Component columbin containing in Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) tuber has mate-assist to suppress fibrous connective tissue hypertrophy.
3, spinal column otch multidigit is followed row position in bladder meridian, and bladder meridian belongs to table, and inventor's clinical experience gained, adds Radix Platycodonis, has priming to enter the effect of urinary bladder channel and channels thereof, contributes to passages through which vital energy circulates unobstructed.
4, postoperative operative incision discomfort is also relevant with the dry impairment of YIN of local blood, and stirring of wind due to deficiency of YIN and numbness, fiber crops itch, so we adopt Potiria pectinifera (Mukller et Tro Sehel) YIN nourishing and YANG strengthening wind-damp dispelling, is the product of reinforcement and elimination in combination, without growing greasy anxiety.
5, Semen Sinapis eliminating phlegm eliminating stagnation, postoperative operative incision discomfort belongs to the operative incision of primary healing, and this kind of operative incision acute stage, is mistake, and cold-phlegm residual in meridians is all more obstinate, so add Semen Sinapis to coordinate Semen Litchi to help tonneau.Semen Sinapis is containing potassium myronate, potassium myronate is met water and is generated volatile oil through the effect of myrosase, and main component is allyl isosulfocyanate, has stimulation, be applied to skin, there is warm sensation and make it rubescent, even causing blister, pustule, so adopt emplastra sinapis powder in prescription of the present invention, be that mustard flour is removed gained after fatty oil, this kind of de-fatty oil method is for conventional in the industry, and emplastra sinapis powder can directly be buied from market, sufficient raw.But because the present invention need to surpass 3 hours in local action, so coordinate Radix Puerariae, Radix Puerariae contains much starch, can alleviate the skin irritation of Semen Sinapis.
6, Magnetitum is originally the product in important city, but rat local topical, and can make local neutrophilic granulocyte engulf reaction increases.
7, avoid using the promoting the circulation of blood medicine of taking offence, reducing local fibroplasia initiating stimulates.
The specific embodiment
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, crude drug weight proportion: 20 parts of Radix Tylophorae arenicolaes, 10 parts of Semen Aesculies, 6 parts of Lignum Pini Nodis, 10 parts of Flos jasmini, 6 parts of Semen Litchis, 10 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 10 parts of Radix Platycodoniss, 10 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 10 parts of Alpinia japonica (Thunb.) Miq.s, 2 parts, emplastra sinapis powder, 6 parts of Magnetitums, 20 parts of Radix Puerariaes.
The preparation method of embodiment 1 is: Radix Tylophorae arenicolae, Semen Aesculi, Lignum Pini Nodi, Flos jasmini, Semen Litchi, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Radix Platycodonis, Potiria pectinifera (Mukller et Tro Sehel), Alpinia japonica (Thunb.) Miq., emplastra sinapis powder (decocting a drug wrapped), Magnetitum, Radix Puerariae mixing and water adding are decocted, after 30 minutes, get filtrate, medicinal residues add water continuation decoction and get filtrate after 20 minutes, twice filtrate merges, be condensed into thick paste, appropriate soak is in healing on operative incision.
Embodiment 2, crude drug weight proportion: 10 parts of Radix Tylophorae arenicolaes, 6 parts of Semen Aesculies, 3 parts of Lignum Pini Nodis, 6 parts of Flos jasmini, 3 parts of Semen Litchis, 6 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 6 parts of Radix Platycodoniss, 6 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 6 parts of Alpinia japonica (Thunb.) Miq.s, 1 part, emplastra sinapis powder, 3 parts of Magnetitums, 10 parts of Radix Puerariaes.
Embodiment 3, crude drug weight proportion: 20 parts of Radix Tylophorae arenicolaes, 10 parts of Semen Aesculies, 6 parts of Lignum Pini Nodis, 10 parts of Flos jasmini, 6 parts of Semen Litchis, 10 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 10 parts of Radix Platycodoniss, 10 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 10 parts of Alpinia japonica (Thunb.) Miq.s, 2 parts, emplastra sinapis powder, 6 parts of Magnetitums, 20 parts of Radix Puerariaes.
Embodiment 4, crude drug weight proportion: 30 parts of Radix Tylophorae arenicolaes, 12 parts of Semen Aesculies, 10 parts of Lignum Pini Nodis, 12 parts of Flos jasmini, 10 parts of Semen Litchis, 12 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 12 parts of Radix Platycodoniss, 12 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 12 parts of Alpinia japonica (Thunb.) Miq.s, 5 parts, emplastra sinapis powder, 10 parts of Magnetitums, 25 parts of Radix Puerariaes.
The Chinese medicine of embodiment 2～4 can be prepared from by following method:
(1) Semen Aesculi, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Flos jasmini, Lignum Pini Nodi, Semen Litchi coarse powder are extracted to volatile oil with vapor distillation respectively, and mixing for standby use after collecting;
(2) emplastra sinapis powder, Magnetitum, Radix Puerariae were pulverized respectively to 150 mesh sieves, and became fine powder standby;
(3) Radix Tylophorae arenicolae, Radix Platycodonis, Alpinia japonica (Thunb.) Miq., Potiria pectinifera (Mukller et Tro Sehel) mix and add 10 times of water yields, decoct with water 2 times, and each 1 hour, collecting decoction, standing; Then toward 95% the ethanol that adds 3～4 times of medicinal liquids in decocting liquid, standing 15 minutes, then with 3000rpm/min centrifugal 20 minutes, get precipitation, spraying is dry, draws just material;
(4) gained volatile oil in step 1 is sprayed in the first material of step 3 gained, add gained fine powder in step 2 to mix, cross 60 mesh sieves, sterilizing, subpackage form.
During use, with warm water, dress the operative incision place after healing.
Effective combination of said medicine, coordinates mutually, effectively reach the object that treatment postoperative wound does not feel like oneself, and side effect is less.The above results is that clinical data fully proves, interrelated data is as follows.
1 object and method
1.1 object
1.1.1 case selection: in January, 2012～2013 spinal surgery in year August, postoperative primary healing patient, uncomfortable 60 examples of the former operative incision of main suit, main suit's discomfort comprises local pain, fiber crops, itches, referred pain, formication, companion or do not accompany operative incision surrounding tissue to harden.Be divided into matched group 20 examples, thick paste group 18 examples and dress group 22 examples.Before three groups of patient treatments, in sex, age, Operative category, operative incision length, compare, difference not statistically significant (P>0.05), has comparability.
1.1.2 inclusive criteria is: 1. spinal surgery is postoperative without other post-operative complication; 2. the postoperative operative incision primary healing of spinal surgery; 3. in postoperative three months of spinal surgery; Operative incision part is without red and swollen heat pain, and gets rid of deep layer and infect; 4. non-diabetic and mental sickness medical history.
1.2 method
1.2.1 Therapeutic Method: matched group is embrocated with safflower oil part, 2 times/d.Thick paste group with the local appropriate soak of gained thick paste in the embodiment of the present invention 1 in healing on operative incision, 2 times/d.Dress group and dress in healing on operative incision with the local appropriate warm water of gained medicated powder in the embodiment of the present invention 2,2 times/d.3 groups of treatments all be take 14 days as 1 course for the treatment of, after the course for the treatment of, add up curative effect.
1.2.2 criterion of therapeutical effect: recovery from illness: clinical symptoms, sign disappear; Effective: clinical symptoms, sign turn for the better by and large, no longer impact life; Effective: clinical symptoms, sign alleviate, but sleep or life still can be affected; Invalid: clinical symptoms, sign are unchanged.
1.2.3 statistical analysis: SPSS13.0 carries out statistical analysis.Measurement data is checked with t, enumeration data χ
2check.
2 results
2.1 3 groups of Comprehensive Clinical curative effects comparison: thick paste group is organized cure rate and extremely obvious (the thick paste group χ of matched group difference with dressing
2=9.89, P<0.05; Dress group χ
2=8.87, P<0.05), thick paste group is organized total effective rate apparently higher than matched group (thick paste group χ with dressing
2=4.94, P<0.05; Dress group χ
2=4.17, P<0.05), see the following form.
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Total effective rate |
| Matched group | 20 | 1(5.00%) | 6(30.00%) | 6(30.00%) | 7(35.00%) | 65.00% |
| Thick paste group | 18 | 9(50.00%) | 6(33.33%) | 2(11.11%) | 1(5.56%) | 94.44% |
| Dress group | 22 | 10(45.45%) | 6(27.27%) | 4(18.18%) | 2(9.09%) | 90.91% |
2.2 3 groups of adverse reactions of patients incidence rates: three groups all do not occur obvious adverse reaction.
3. conclusion
This result of study shows, use thick paste group of the present invention and dress group cure rate and total effective rate apparently higher than matched group, illustrate the present invention after iatrotechnics, healed operative incision have aspect doing not feel like oneself untoward reaction gently, the higher advantage of safety.
Claims (2)
1. an otch care drug after spinal operation, is characterized in that being prepared from by the crude drug of following weight proportion: 10～30 parts of Radix Tylophorae arenicolaes, 6～12 parts of Semen Aesculies, 3～10 parts of Lignum Pini Nodis, 6～12 parts of Flos jasmini, 3～10 parts of Semen Litchis, 6～12 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 6～12 parts of Radix Platycodoniss, 6～12 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 6～12 parts of Alpinia japonica (Thunb.) Miq.s, 1～5 part, emplastra sinapis powder, 3～10 parts of Magnetitums, 10～25 parts of Radix Puerariaes.
2. otch care drug after a kind of spinal operation according to claim 1, is characterized in that being prepared from by the crude drug of following weight proportion: 20 parts of Radix Tylophorae arenicolaes, 10 parts of Semen Aesculies, 6 parts of Lignum Pini Nodis, 10 parts of Flos jasmini, 6 parts of Semen Litchis, 10 parts of Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae)s, 10 parts of Radix Platycodoniss, 10 parts of Potiria pectinifera (Mukller et Tro Sehel)s, 10 parts of Alpinia japonica (Thunb.) Miq.s, 2 parts, emplastra sinapis powder, 6 parts of Magnetitums, 20 parts of Radix Puerariaes.
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| CN201310749681.7A CN103656438B (en) | 2013-12-31 | 2013-12-31 | Nursing medicine for spine postoperative cuts |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233438A (en) * | 2017-07-04 | 2017-10-10 | 袁硕 | A kind of spinal surgery postoperative wound nursing powder and preparation method thereof |
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|---|---|---|---|---|
| CN102441044A (en) * | 2011-12-22 | 2012-05-09 | 许从玉 | Care solution for wound cleaning |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN103405559A (en) * | 2013-08-30 | 2013-11-27 | 封秀花 | Clinical wound nursing medicine |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102441044A (en) * | 2011-12-22 | 2012-05-09 | 许从玉 | Care solution for wound cleaning |
| CN102631423A (en) * | 2012-05-09 | 2012-08-15 | 白玲强 | Care solution for wound cleaning |
| CN103405559A (en) * | 2013-08-30 | 2013-11-27 | 封秀花 | Clinical wound nursing medicine |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107233438A (en) * | 2017-07-04 | 2017-10-10 | 袁硕 | A kind of spinal surgery postoperative wound nursing powder and preparation method thereof |
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