CN104645052A - Preparation method of external medicine for nerve injury - Google Patents
Preparation method of external medicine for nerve injury Download PDFInfo
- Publication number
- CN104645052A CN104645052A CN201510108972.7A CN201510108972A CN104645052A CN 104645052 A CN104645052 A CN 104645052A CN 201510108972 A CN201510108972 A CN 201510108972A CN 104645052 A CN104645052 A CN 104645052A
- Authority
- CN
- China
- Prior art keywords
- parts
- nerve injury
- folium
- filtrate
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation method of an external medicine for nerve injury to solve the problem in treatment of common peroneal nerve injury. The preparation method comprises the following steps: mixing 10-30 parts of bittersweet herb, 6-12 parts of edible tulip, 3-10 parts of schefflera arboricola hayata, 6-12 parts of herb of paniculate spotflower, 3-10 parts of flueggea suffruticosa, 6-12 parts of mulberry, 6-12 parts of glossy privet fruit, 6-12 parts of fructus aurantii immaturus, 6-12 parts of alate senna leaf, 1-5 parts of glechoma longituba, 3-10 parts of amblystegium serpens and 10-25 parts of cladostachys amaranthoides; adding water and decocting; 30 minutes later, filtering to obtain the filtrate; adding water into the residue and decocting for 20 minutes; filtering to obtain the filtrate; mixing the two filtrates; and concentrating, drying, crushing, blending and applying. Clinical experiments prove that the external medicine has the characteristics of good curative effect and relatively high safety when used for treating common peroneal nerve injury and is worth clinical application and promotion.
Description
Technical field
The present invention is patent application " a kind of externally-applied medicinal composition for rehabilitation after the common peroneal nerve injury " (application number: divisional application 2013103601481) submitted on August 19th, 2013.Relate to drug world, be specifically related to a kind of externally-applied medicinal composition for rehabilitation after common peroneal nerve injury.
Background technology
Common peroneal nerve (the nervus peroneus communis) neck of fibula that detours place location tables is shallow, and be close to periosteum, therefore fracture of fibular neck or use fixation device can not be involved at that time, shank extensor is caused to paralyse and cause drop foot, there is dorsiflexion of foot, dysfunction of turning up, in varus apron deformity.And stretch thumb, stretch apodization function and lose, in flexion, and before anterolateral crural and instep, inner side sensory disturbance.Reparation after common peroneal nerve injury is one of the difficult problem in Neurology Department field.The essence of neuranagenesis is that injured neurons forms new aixs cylinder, can rebuild synaptic contact, and recover normal function with target organ.Wherein any one link goes wrong. all will affect the functional rehabilitation after common peroneal nerve injury.
The common peroneal nerve injury medicine of current Clinical practice has exogenous neurotrophic factor, adenylic acid Cycloxygenase activator and cyclic adenosine monophosphate, Protein kinase C, inflammatory factor, vitamin B complex etc.Nerve growth factor (nerve growth factor in its exogenous neurotrophic factor, NGF) curative effect is the most reliable, but also there is side effect in application NGF: sprouting of int normal neuronal aixs cylinder, can cause the untoward reaction such as chronic pain and abnormal neuron reflection to occur.Therefore exploration one class of still needing at present can promote neural growth fast, can ensure again the inexpensive drugs of regenerated nervous fibers function.
Chinese medicine after common peroneal nerve injury is the based uplink gas promoting blood circulation to remove obstruction in the collateral being vigorate qi and replenish the blood then more, but actual clinical effect not obvious.Acupuncture effect is obviously better than Chinese medicine, but patient is difficult to adhere to.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provides a kind of curative effect certainly and the little externally-applied medicinal composition for rehabilitation after common peroneal nerve injury of side effect.
The technical scheme that the present invention solves its technical problem is: get Herba Solani Lyrati 10 ~ 30 parts, Pseudobulbus Cremastrae Seu Pleiones 6 ~ 12 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 3 ~ 10 parts, Herba Spilanthis Acmellae 6 ~ 12 parts, Cacumen Securinegae Suffruticosae 3 ~ 10 parts, Fructus Mori 6 ~ 12 parts, Fructus Ligustri Lucidi 6 ~ 12 parts, Fructus Aurantii Immaturus 6 ~ 12 parts, Folium Cassiae Alatae 6 ~ 12 parts, HUOXUEDAN 1 ~ 5 part, Folium Salicis Babylonicae moss 3 ~ 10 parts, 10 ~ 25 parts of mixing and water addings decoctions of nine layers of wind, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, and concentrate drying dresses after pulverizing.
Wherein said: Herba Solani Lyrati is the herb of plant of Solanaceae Herba Solani Lyrati Solanum lyratum Thunb..Sweet in the mouth; Bitter; Cold in nature.Return liver; Gallbladder; Kidney channel.Merit can clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.
Pseudobulbus Cremastrae Seu Pleiones is orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides(Franch.) the dry pseudobulb of Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Nature and flavor are sweet, micro-pungent, cold.Enter liver, stomach warp.Merit can heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), is Araliaceae Schefflera plant schefflera arboricola Scheffleva arboricola Hayata and Schefflera venulosa (Wight et Arn.) Harms S.venulosa (Wight et Arn.) Harms, is used as medicine with stem and leaf.Nature and flavor are bitter, sweet, temperature.Merit can pain relieving dissipating blood stasis, detumescence.
Herba Spilanthis Acmellae is the herb of feverfew Herba Cancriniae lasiocarpae Spilanthes paniculata Wall.ex DC..Acrid in the mouth; Bitter; Slightly warm in nature; Mild toxicity.Merit can relieving cough and asthma; Detoxification and promoting urination; Reducing swelling and alleviating pain.
Cacumen Securinegae Suffruticosae is euphorbia plant Suffrutescent Securinega Twig Securinega suffruticosa(Pal1.) browse of Rehd. or root.Acrid in the mouth; Bitter; Slightly warm in nature.Return liver; Kidney; Spleen channel.Merit can expelling wind and activating blood circulation; The strong muscle of kidney tonifying.
Fructus Mori is the dry fruit ear of moraceae plants Mulberry Morus alba L..Nature and flavor are sweet, sour, cold.GUIXIN, liver, kidney channel.Merit can be enriched blood YIN nourishing, promotes the production of body fluid and moisturizes.
Fructus Ligustri Lucidi is the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi Ligustrum lucidum Ait..Nature and flavor sweet, bitter, cold.Return liver, kidney channel.Merit can nourishing the liver and kidney, improving eyesight black hair.
Fructus Aurantii Immaturus is the dry young fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety or Fructus Citri sinensis Citrus sinensis Osbeck.Merit can dispelling the stagnated QI intestinal stasis relieving.Nature and flavor are bitter, pungent, sour, temperature.Return spleen, stomach warp.Merit can dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.
Folium Cassiae Alatae, is pulse family Folium Cassiae Alatae Cassia alata L., is used as medicine with leaf.Nature and flavor are pungent, temperature.Merit can parasite killing, antipruritic.
HUOXUEDAN is labiate HUOXUEDAN G.hederacea L.var .longituba Nakai; The herb of G.hederacea auct.non L..Bitter in the mouth; Pungent; Cool in nature.Return liver; Gallbladder; Urinary bladder channel.Merit can dampness removing treating stranguria; Heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.
Folium Salicis Babylonicae moss is Amblystegiaceae Folium Salicis Babylonicae moss Amblystegium serpens(Hedw.) plant of B.S.G..Nature and flavor are puckery; Flat.Merit can astringing to arrest bleeding.
Nine layers of wind are the dry rattan of leguminous plant spatholobus suberectus Spatholobus suberectus Dunn.Nature and flavor are bitter, sweet, temperature.Return liver, kidney channel.Merit can be enriched blood, and invigorates blood circulation, dredging collateral.
Composition principle: at present after common peroneal nerve injury repairing and treating in Neurology Department category Chinese medicine be the based uplink gas promoting blood circulation to remove obstruction in the collateral of vigorate qi and replenish the blood, but actual clinical effect not obvious more.Inventor's clinical research for many years finds, common peroneal nerve injury is except qi depression to blood stasis, after common peroneal nerve injury, limbs channels is obstructed, stay poly-not loose relevant to body fluid, surely belong to the traditional Chinese medical science and be referred to as " phlegm stagnating in meridian ", accumulation of phlegm blocks, in network, QI and blood is not all right, also blood stasis can be caused, and " accumulation of blood is both of a specified duration, also can turn to expectorant water " (" treatise on blood trouble " rolls up five).So, because expectorant causes the stasis of blood, the long-pending stasis of blood is reduced phlegm, phlegm and blood stasis, and glue work is for suffering from, and then obstructed till passages through which vital energy circulates, four ends do not reach and produce the malnutrition in Substance P region.Therefore, after common peroneal nerve injury, main pathological basis is be the accumulation of phlegm folder stasis of blood.Expectorant, the stasis of blood are pathological product, are again paathogenic factors; Both be the mark of disease, being also disease basis, is wherein major pathogenetic factor especially with accumulation of phlegm.Therefore its treatment, should invigorate blood circulation, eliminate the phlegm, eliminating stagnation, dredging collateral go forward side by side, local recovery after common peroneal nerve injury can be promoted.
Compared with prior art, the present invention has following characteristics.
1, Herba Solani Lyrati and Pseudobulbus Cremastrae Seu Pleiones coordinate for monarch drug, wherein: Herba Solani Lyrati merit can clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, inventor's cell culture experiments proves: Herba Solani Lyrati decocting liquid has unique logical stagnant effect after being used for common peroneal nerve injury reparation, its mechanism of action may be that Herba Solani Lyrati can promote local growth associated protein (Growth associated protein-43, GAP-43) synthesis, and specific proteins GAP-43 is in the growth of nerve fiber, grow, the important roles such as the maintenance of axon regeneration and synaptic function, and participate in the adjustment of neurotransmitter regulator, grow again neural or can determine to grow along correct direction with inducing neural projection in regeneration, and there is no the side effect of sprouting of that int normal neuronal aixs cylinder of NGF, and Pseudobulbus Cremastrae Seu Pleiones dispersing strength is strong, the logical stagnant effect of Herba Solani Lyrati can be strengthened, reach the effect eliminating the retardance of meridians accumulation of phlegm.We avoid using eliminating phlegm eliminating stagnation medicine, and its reason is that meridians stagnation of phlegm is different from visible phlegm, inventor's clinical experience gained: use such medicine, nerve conduction irritability, easily causes the untoward reaction such as chronic pain and abnormal neuron reflection.
2, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) pain relieving dissipating blood stasis for subsidence of swelling, Herba Spilanthis Acmellae expelling wind and removing dampness, reducing swelling and alleviating pain, auxiliary Herba Solani Lyrati and Pseudobulbus Cremastrae Seu Pleiones dispel the phlegm-damp in meridians, remove wet retention of phlegm and amass this pathologic basis.
3, Fructus Mori is enriched blood yin nourishing, Fructus Ligustri Lucidi nourishing the liver and kidney, and Fructus Aurantii Immaturus dispelling the stagnated QI reduces phlegm, and carries out training respectively and mends, help Herba Solani Lyrati processed, Pseudobulbus Cremastrae Seu Pleiones, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Herba Spilanthis Acmellae from phlegm-damp upstream and downstream, prevents that it is got rid of evils too and just hinders.
4, nine layers of wind are enriched blood promoting blood circulation to remove obstruction in the collateral, the strong muscle of Cacumen Securinegae Suffruticosae expelling wind and activating blood circulation, kidney tonifying, and two taste blood system medicines, return liver, kidney channel, reinforcement and elimination in combination, and motionless blood of invigorating blood circulation, and have the strong muscle effect of dredging collateral.
5, inventor's experimentation shows: low dose of HUOXUEDAN can increase neurocyte liveness effectively.
6, Folium Cassiae Alatae can reduce the local skin stimulation of we, is beneficial to Drug Percutaneous Absorption rate.
7, in one row falls apart dredging collateral medicine, add low dose of Folium Salicis Babylonicae moss, play assistant and make use, reduce side effect.
8, medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, and each raw material dosage is for all to have good curative effect in following weight parts scope.
Detailed description of the invention
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, crude drug weight proportion: Herba Solani Lyrati 20 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 parts, Herba Spilanthis Acmellae 10 parts, Cacumen Securinegae Suffruticosae 6 parts, Fructus Mori 10 parts, Fructus Ligustri Lucidi 10 parts, Fructus Aurantii Immaturus 10 parts, Folium Cassiae Alatae 10 parts, HUOXUEDAN 2 parts, Folium Salicis Babylonicae moss 6 parts, nine layers of wind 20 parts.
The preparation method of embodiment 1 is: Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Herba Spilanthis Acmellae, Cacumen Securinegae Suffruticosae, Fructus Mori, Fructus Ligustri Lucidi, Fructus Aurantii Immaturus, Folium Cassiae Alatae, HUOXUEDAN, Folium Salicis Babylonicae moss, nine layers of wind mixing and water adding are decocted, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, and concentrate drying dresses after pulverizing.
Embodiment 2, crude drug weight proportion: Herba Solani Lyrati 10 parts, Pseudobulbus Cremastrae Seu Pleiones 6 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 3 parts, Herba Spilanthis Acmellae 6 parts, Cacumen Securinegae Suffruticosae 3 parts, Fructus Mori 6 parts, Fructus Ligustri Lucidi 6 parts, Fructus Aurantii Immaturus 6 parts, Folium Cassiae Alatae 6 parts, HUOXUEDAN 1 part, Folium Salicis Babylonicae moss 3 parts, nine layers of wind 10 parts.
Embodiment 3, crude drug weight proportion: Herba Solani Lyrati 20 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 parts, Herba Spilanthis Acmellae 10 parts, Cacumen Securinegae Suffruticosae 6 parts, Fructus Mori 10 parts, Fructus Ligustri Lucidi 10 parts, Fructus Aurantii Immaturus 10 parts, Folium Cassiae Alatae 10 parts, HUOXUEDAN 2 parts, Folium Salicis Babylonicae moss 6 parts, nine layers of wind 20 parts.
Embodiment 4, crude drug weight proportion: Herba Solani Lyrati 30 parts, Pseudobulbus Cremastrae Seu Pleiones 12 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10 parts, Herba Spilanthis Acmellae 12 parts, Cacumen Securinegae Suffruticosae 10 parts, Fructus Mori 12 parts, Fructus Ligustri Lucidi 12 parts, Fructus Aurantii Immaturus 12 parts, Folium Cassiae Alatae 12 parts, HUOXUEDAN 5 parts, Folium Salicis Babylonicae moss 10 parts, nine layers of wind 25 parts.
The Chinese medicine of embodiment 2 ~ 4 can be prepared from by following method:
(1) Fructus Ligustri Lucidi, Pseudobulbus Cremastrae Seu Pleiones, Cacumen Securinegae Suffruticosae coarse powder are extracted volatile oil with vapor distillation respectively, and mixing for standby use after collecting;
(2) HUOXUEDAN, Folium Salicis Babylonicae moss are pulverized 150 mesh sieves, and become fine powder for subsequent use;
(3) Herba Solani Lyrati, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Herba Spilanthis Acmellae, Fructus Mori, Folium Cassiae Alatae, Fructus Aurantii Immaturus, nine layers of wind are decocted with water 2 times, filter, merging filtrate, is concentrated into relative density 1.1, obtains Aqueous extracts;
(4) fine powder of the volatile oil of step 1 gained, step 2 gained is added the Aqueous extracts of step 3 gained, stir, be concentrated into relative density 1.36.
In prioritization scheme, described simmer down to concentrating under reduced pressure.
The efficient combination of said medicine, coordinates mutually, invigorates blood circulation, eliminates the phlegm, dredging collateral, effectively reach the object promoting CO2 laser weld after common peroneal nerve injury treatment, and side effect is less.The above results is clinical data sufficient proof, and interrelated data is as follows.
1 object and method.
1.1 object.
1.1.1 case selection: the compressing that in January, 2011 ~ 2013 are accepted for medical treatment year January or soft tissue contusion cause common peroneal nerve injury 69 example, and common peroneal nerve crack conditions does not all appear in all patients.Wherein male 46 example, women 23 example, 14 ~ 67 years old age, average 27.9 years old.
1.1.2 divide into groups: be divided into matched group 24 example at random, dress group 22 example, unguentum group 23 is routine.Compare in sex, age, the state of an illness before three groups of patient treatments, no significant difference (P>0.05), has comparability.
1.2 method.
1.2.1 administering mode: matched group takes conventional therapy and function to rebuild, if desired row plaster slab fix, dress group adopts embodiment 1 gained medicament local to dress on the basis of matched group, unguentum group adopts embodiment 3 gained unguentum Local out dressing on the basis of matched group, dress group and unguentum group within every 3 days, change dressings once, after within after treatment 4 weeks, removing below elbow cast holder, every medication 6 days intervals expose 1 day, and total course for the treatment of is 16 weeks.
1.2.2 observation index and evaluation methodology: check in 16 weeks after treatment, measures the 30g pressure sensation of skin in injured nerve domination region respectively, 2g sense of touch, the 5g pain sensation and 2 differentiates and feel that patient's numbers of <10 mm and percent and differentiate the numerical value of feeling and contrast to make and compare at 2.
2 results.
2.1 latter 16 weeks of treatments, compare for three groups of pressure sensations, sense of touch, the pain sensation and 2 patients differentiating feel >10mm, the results are shown in following table:
| Group | Number of cases | Pressure sensation (%) | Sense of touch | The pain sensation | Differentiate for 2 and feel |
| Matched group | 24 | 70.83% | 70.83% | 41.67% | 20.83% |
| Dress group | 22 | 100% | 100% | 72.73% | 50% |
| Unguentum group | 23 | 100% | 100% | 82.61% | 69.57% |
The present invention of result display application dresses or the patient of unguentum external application differentiates recovery feels in apparently higher than blank group (P<0.05) the pain sensation and at 2.
2.2 3 groups of adverse reactions of patients incidence rates compare: three groups all do not occur any obvious adverse reaction record, dress group and unguentum group local skin there is not obvious red and swollen pruritus, the equal omnidistance completed treatment of all cases.
3. conclusion.
This result of study shows, and the present invention dresses or unguentum external application can accelerate the nervous tissue after repairing damage, improves nervous tissue and transmits and dysbolismus.And do not find in following up a case by regular visits to occur any untoward reaction in medication process, illustrate that this externally-applied medicinal composition clinical practice is safe.
Claims (1)
1. the preparation method of external used medicine after a nerve injury, it is characterized in that: get Herba Solani Lyrati 10 ~ 30 parts, Pseudobulbus Cremastrae Seu Pleiones 6 ~ 12 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 3 ~ 10 parts, Herba Spilanthis Acmellae 6 ~ 12 parts, Cacumen Securinegae Suffruticosae 3 ~ 10 parts, Fructus Mori 6 ~ 12 parts, Fructus Ligustri Lucidi 6 ~ 12 parts, Fructus Aurantii Immaturus 6 ~ 12 parts, Folium Cassiae Alatae 6 ~ 12 parts, HUOXUEDAN 1 ~ 5 part, Folium Salicis Babylonicae moss 3 ~ 10 parts, 10 ~ 25 parts of mixing and water addings decoctions of nine layers of wind, filtrate is got after 30 minutes, medicinal residues add water continue decoction get filtrate after 20 minutes, twice filtrate merges, and concentrate drying dresses after pulverizing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510108972.7A CN104645052A (en) | 2013-08-19 | 2013-08-19 | Preparation method of external medicine for nerve injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510108972.7A CN104645052A (en) | 2013-08-19 | 2013-08-19 | Preparation method of external medicine for nerve injury |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310360148.1A Division CN103405649B (en) | 2013-08-19 | 2013-08-19 | External pharmaceutical composition for recovery after nervus peroneus communis injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104645052A true CN104645052A (en) | 2015-05-27 |
Family
ID=53237022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510108972.7A Pending CN104645052A (en) | 2013-08-19 | 2013-08-19 | Preparation method of external medicine for nerve injury |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104645052A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105214045A (en) * | 2015-10-27 | 2016-01-06 | 刘小民 | The preparation method of external used medicine and medicine composition after a kind of nerve injury |
-
2013
- 2013-08-19 CN CN201510108972.7A patent/CN104645052A/en active Pending
Non-Patent Citations (4)
| Title |
|---|
| 王爱国等: "神经营养类中药的研究进展", 《第十四届全国中西医结合骨伤科学术研讨会论文集》 * |
| 王爱国等: "神经营养类中药研究进展", 《实用中医药杂志》 * |
| 田家敏: "中医辨证治疗腓总神经损伤 ", 《辽宁中医学院学报》 * |
| 田家敏: "中医辨证治疗腓总神经损伤", 《辽宁中医学院学报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105214045A (en) * | 2015-10-27 | 2016-01-06 | 刘小民 | The preparation method of external used medicine and medicine composition after a kind of nerve injury |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101559195B (en) | Epilepsy therapy capsule and preparation method thereof | |
| CN104524208A (en) | Medicament for treatment of sciatica and preparation method | |
| CN103656325B (en) | A kind of otch nursing thing for the treatment of postoperative wound and doing not feel like oneself | |
| CN104491236A (en) | Traditional Chinese medicine preparation for treating essential hypertension and preparation method for traditional Chinese medicine preparation | |
| CN103393954B (en) | A kind of ointment preparation method for rehabilitation after common peroneal nerve injury | |
| CN103405649B (en) | External pharmaceutical composition for recovery after nervus peroneus communis injury | |
| CN103393850B (en) | Drug for median nerve injury | |
| CN104645052A (en) | Preparation method of external medicine for nerve injury | |
| CN103393837B (en) | External medicine for curing radial nerve palsies | |
| CN105311140A (en) | Pharmaceutical composition for treating cervical spondylosis and preparation method thereof | |
| CN103405648B (en) | External care substance for ulnar nerve injury | |
| CN103417844B (en) | Method for preparing ointment used for nerve injury caused by waist trauma | |
| CN103405650B (en) | External medicine for nerve injury caused by wrist traumas | |
| CN103735874B (en) | A kind of nursing powder for wound after wound healing and preparation method thereof | |
| CN104688922A (en) | External mixing and applying agent for treating radial nerve palsies | |
| CN101983712A (en) | Novel medicament for treating coronary heart disease | |
| CN103432385B (en) | Medicine for peripheral nerve injury postoperation recovery | |
| CN103463419A (en) | Preparation method of ointment used for peripheral nerve injury postoperative repair | |
| CN103393836A (en) | Preparation method of paste for curing paralysis of the radial nerve | |
| CN104922488A (en) | Traditional Chinese medicine composition for preventing and curing Parkinson's disease or Parkinson's disease motor complications and preparing method and application thereof | |
| CN104721567A (en) | Externally applied nursing dressing medicament after nerve injuries | |
| CN104491237A (en) | Use of traditional Chinese medicine preparation in preparing medicines for treating primary hypertension | |
| CN104587297A (en) | Traditional Chinese medicine capsule for treating scleroderma and preparation method thereof | |
| CN104706964A (en) | Preparation method of mixed application for treating peripheral nerve injuries | |
| CN104758539A (en) | Traditional Chinese medicine composition for treating debilitation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150527 |