CN1416830A - Galactic medicine and its prepn - Google Patents
Galactic medicine and its prepn Download PDFInfo
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- CN1416830A CN1416830A CN 01127576 CN01127576A CN1416830A CN 1416830 A CN1416830 A CN 1416830A CN 01127576 CN01127576 CN 01127576 CN 01127576 A CN01127576 A CN 01127576A CN 1416830 A CN1416830 A CN 1416830A
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Abstract
The galactic medicine for treating milk secretion deficiency is prepared with nine kinds of Chinese medicinal materials including astragalus root, Dangshen, white atractylodes rhizome, angelica, Chuanxiong rhizome, etc. and through decoction, depression concentrating and pelletizing. Clinical application shows that the medicine has excellent curative effect on milk secretion deficiency caused by vital energy and blood deficiency.
Description
The present invention relates to a kind of Lactogenic medicine that is used for the puerperal hypogalactia women, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, and the present invention relates to the preparation method of this Lactogenic medicine simultaneously.
Because breast milk is the optimal nutriment of baby, its nutritive value is higher than any milk replacer, and breast milk all has special function at aspects such as threpsology, immunology and psychology, and infantile health is grown up, play an important role, so breast feeding has many advantages than artificial feeding; Milk is QI and bloodization, relies gas with row, and the puerpera produces, postpartum hemorrhage is too much, causes deficiency of qi and blood, so that milkization is given birth to weary source; The deficiency of vital energy then gas is capable weak, and anemia makes the liver body lose again and supports, and produces the thing anxiety in addition, makes feelings will not relax, and it is not smooth can to cause irritability yet, makes the liver failing to maintain the normal flow of QI, and breast is capable not smooth, so that causes puerpera's agalactia or hypogalactia; At present, run into the puerpera of hypogalactia or hypogalactia clinically, often adopt the Chinese medicine decoction treatment, patient feels trouble, the curative effect instability; In addition, the lactogenic Chinese patent medicine of domestic approved such as lactogenesis electuary, stimulating milk secretion spring loose etc. and all to add the animal drug Squama Manis in the prescription, and Squama Manis is rare the watching for animals of national two classes, can not satisfy the medication needs.
The object of the present invention is to provide the Lactogenic medicine of a kind of benefiting QI and nourishing blood, circulation of qi promoting lactogenesis, it selects the natural edible vegetable drug for use, need not to add animal drug, to puerperal because of the puerpera that deficient qi and blood causes hypogalactia, can obviously increase breast filling degree and galactopoiesis amount after taking.
Another object of the present invention provides the preparation method of this Lactogenic medicine.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to the puerperal hypogalactia cause of disease, pathogenesis, experience and achievement in research to the successive dynasties physician are constantly perfect, filter out the natural edible-plant medical material of invigorating the spleen and replenishing QI, nourshing blood and promoting blood circulation, the capable breast of promoting the circulation of QI, according to the theory of Chinese medical science prescription, skim the cream off milk, make it give full play to the effect of vigorate qi and replenish the blood, circulation of qi promoting lactogenesis.
For achieving the above object, the component and the content of required pharmaceutical composition is in every 1000g preparation: Radix Astragali 100g-200g, Radix Codonopsis 100g-180g, Rhizoma Atractylodis Macrocephalae 50g-130g, Radix Angelicae Sinensis 100g-180g, Rhizoma Chuanxiong 60g-120g, Radix Bupleuri 50g-130g, Semen Vaccariae 60g-120g, Radix Rhapontici 50g-130g, Radix Hemerocallis 50g-100g.
The preferred ingredient of required pharmaceutical composition and content are in every 1000g preparation: Radix Astragali 135g-160g, Radix Codonopsis 135g-160g, Rhizoma Atractylodis Macrocephalae 90g-105g, Radix Angelicae Sinensis 135g-160g, Rhizoma Chuanxiong 90g-105g, Radix Bupleuri 90g-105g, Semen Vaccariae 90g-105g, Radix Rhapontici 90g-105g, Radix Hemerocallis 70g-80g.
The best composition of required pharmaceutical composition and content are in every 1000g preparation: Radix Astragali 146g, Radix Codonopsis 146g, Rhizoma Atractylodis Macrocephalae 98g, Radix Angelicae Sinensis 146g, Rhizoma Chuanxiong 98g, Radix Bupleuri 98g, Semen Vaccariae 98g, Radix Rhapontici 98g, Radix Hemerocallis 73g.
The preparation method of said components being made medicine of the present invention is: at first with after said medicine cleaning, the remove impurity, add water 8Kg-12Kg and soak after 12 hours, heated and boiled 2 hours leaches medicinal liquid; Medicinal residues add water 6Kg-10Kg, and heated and boiled 1 hour leaches medicinal liquid; Medicinal residues add water 5Kg-8Kg again, and heated and boiled 1 hour leaches medicinal liquid; Merge the extractum that the medicinal liquid that leaches for three times is evaporated to relative density 130-135 (80 ℃ of surveys), be cooled to room temperature; Learn from else's experience and pulverize the Icing Sugar 400g-600g that 80 mesh sieves are crossed in the back, cross the dextrin 300g-500g of 120 mesh sieves, put mixing in the blender, under agitation add extractum, continue to stir into soft material, granulate through 14 mesh sieves, granule is in 60-70 ℃ of aeration-drying, dry grain removes micro-fine powder with 40 mesh sieves sieve behind 12 mesh sieve granulate, make 1000g lactogenic granule.
Milk is QI and blood instituteization, and deficient qi and blood is controlled and must heavily be filled blood.Between right gas and the blood, qi promoting blood production, qi as the commander of blood; The woman of new product, blood loses greatly, and principal is busy enough with one's own affairs, can be with what to change breast, the full merit that relies gas of breast is changed it with promoting the circulation of blood.So this prescription is with Radix Astragali invigorating the spleen and replenishing QI, be monarch drug as a means of the source of hemopoietic, be aided with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Chuanxiong benefiting QI and nourishing blood and invigorate blood circulation and be ministerial drug, Radix Codonopsis is sweet flat, and merit is arrogated to oneself invigorating the spleen and replenishing QI; Rhizoma Atractylodis Macrocephalae sweetness and bitterness is warm in nature, is longer than the spleen strengthening and damp drying, Radix Codonopsis and the Rhizoma Atractylodis Macrocephalae mutually 5, principal drug assistance replenishing QI to invigorate the spleen; Radix Angelicae Sinensis sweet in the mouth suffering is warm in nature, is the key medicine of enriching blood, and the hot temperature of loosing of Rhizoma Chuanxiong is logical, is gas medicine in the blood, the kind mediation of property, and the special blood-activating and qi-promoting of merit, Radix Angelicae Sinensis, shared the enriching blood of Rhizoma Chuanxiong are invigorated blood circulation; Monarch-minister drug share the prosperous blood of gas and gives birth to, and it is active to make milkization give birth to.Liver controlling conveyance and dispersion, the irritability bar reaches, and lactogenic is then unobstructed, and the side transfers smooth irritability with Radix Bupleuri, and the capable breast of promoting the circulation of QI is an adjuvant drug; Also be adjuvant drug with Semen Vaccariae, Radix Rhapontici, Radix Hemerocallis dredging collateral for promoting lactation again; It is logical that the Semen Vaccariae hardship is let out a surname, walks and do not keep, and sensible blood vessels are longer than stimulating milk secretion, and the Radix Rhapontici purging with bitter and cold drugs is the medicine of cold tonneau, the merit of tool heat clearing away promoting the circulation of blood lactogenesis; Radix Hemerocallis is hidden sweet cool in nature, the effect of tool clearing heat and freeing strangury stimulating milk secretion; Three medicines share the principal drug assistance dredging collateral for promoting lactation.
The present invention shows through No.1 Hospital Affiliated to Beijing Medical Univ., Hospital Affiliated to Shandong Medical College and Shandong Prov. Hospital clinical trial, lactogenic granule of the present invention, to because of the hypogalactia that deficient qi and blood causes better curative effect being arranged puerperal, can obviously increase breast filling degree and galactopoiesis amount, can reach from neonatal weight increase situation analysis and satisfy the neonatal development requirement.General beginning medication in 72 hours puerperal, each 20g, every day three times, its effect occurs after taking 1-2 days, reaches significance degree in 3-4 days, so be advisable 4 days course of treatment; The puerpera who the has distension sensation that milk obviously increases so that the full generation of suckling fore udder height is stronger after taking 1-2 days.Deficient qi and blood disease to the puerpera also has significant curative effect, and the deficient qi and blood sings and symptoms of the most puerperas after the treatment in 4 days disappears, and it is normal that picture of the tongue and pulse condition recover.Organize in contrast with the lactogenesis electuary in addition and compare test, the blood PRL fall of this group is starkly lower than matched group, and E
2Fall apparently higher than matched group, therefore, the PRL/E of this group
2Just apparently higher than matched group; PRL can promote development of breast and galactopoiesis, and E
2Suppress galactopoiesis, this shows that the particulate clinical effectiveness of lactogenic is better than the lactogenesis electuary.The clinical safety result of the test: have no adverse reaction after taking this medicine, the hematuria routine, liver, renal function and cardiac function all have no adverse effects, and the puerpera normally returns to the past in the uterus, and unusual lochia appears in none example.
Provide the component and the content catalog of embodiment of the invention pharmaceutical composition below:
The pharmaceutical composition that each embodiment provides in this table is 1000g lactogenic granule required component and content, and unit is gram.
Component with embodiment three in the table is an example below, describes the preparation method of medicine of the present invention in detail:
After each medical material cleaning, remove impurity in the component, add water 10Kg and soak after 12 hours, heated and boiled 2 hours leaches medicinal liquid; Medicinal residues add water 8Kg, and heated and boiled 1 hour leaches medicinal liquid; Medicinal residues add water 6Kg again, and heated and boiled 1 hour leaches medicinal liquid; Merge the medicinal liquid that leaches for three times is evaporated to relative density 130-135 (80 ℃ of surveys) again after thin film concentrator carries out pre-concentration extractum, by control extractum relative density, make the effective component content of preparation keep stable, extractum is cooled to room temperature; Learn from else's experience and pulverize the Icing Sugar 480g that 80 mesh sieves are crossed in the back, cross the dextrin 420g of 120 mesh sieves, put mixing in the blender, under agitation add extractum, continue to stir into soft material, granulate through 14 mesh sieves, granule is in 60-70 ℃ of aeration-drying, dry grain removes micro-fine powder with 40 mesh sieves sieve behind 12 mesh sieve granulate, make 1000g lactogenic granule.
Claims (6)
1, a kind of Lactogenic medicine is characterized in that: the component of required pharmaceutical composition and content are in every 1000g preparation: Radix Astragali 100g-200g, Radix Codonopsis 100g-180g, Rhizoma Atractylodis Macrocephalae 50g-130g, Radix Angelicae Sinensis 100g-180g, Rhizoma Chuanxiong 60g-120g, Radix Bupleuri 50g-130g, Semen Vaccariae 60g-120g, Radix Rhapontici 50g-130g, Radix Hemerocallis 50g-100g.
2, Lactogenic medicine according to claim 1 is characterized in that: the preferred ingredient of required pharmaceutical composition and content are in every 1000g preparation: Radix Astragali 135g-160g, Radix Codonopsis 135g-160g, Rhizoma Atractylodis Macrocephalae 90g-105g, Radix Angelicae Sinensis 135g-160g, Rhizoma Chuanxiong 90g-105g, Radix Bupleuri 90g-105g, Semen Vaccariae 90g-105g, Radix Rhapontici 90g-105g, Radix Hemerocallis 70g-80g.
3, Lactogenic medicine according to claim 1 and 2 is characterized in that: the best composition of required pharmaceutical composition and content are in every 1000g preparation: Radix Astragali 146g, Radix Codonopsis 146g, Rhizoma Atractylodis Macrocephalae 98g, Radix Angelicae Sinensis 146g, Rhizoma Chuanxiong 98g, Radix Bupleuri 98g, Semen Vaccariae 98g, Radix Rhapontici 98g, Radix Hemerocallis 73g.
4, according to claim 1,2 or 3 described Lactogenic medicines, it is characterized in that: described preparation is a said fixedly preparation on the pharmaceutics.
5, Lactogenic medicine according to claim 4 is characterized in that: described preparation is a dissolved granule.
6, the preparation method of the described Lactogenic medicine of claim 5 is characterized in that: after said medicine cleaning, remove impurity, add water 8Kg-12Kg and soak after 12 hours, heated and boiled 2 hours leaches medicinal liquid; Medicinal residues add water 6Kg-10Kg, and heated and boiled 1 hour leaches medicinal liquid; Medicinal residues add water 5Kg-8Kg again, and heated and boiled 1 hour leaches medicinal liquid; Merge the extractum that the medicinal liquid that leaches for three times is evaporated to relative density 1.30-1.35 (80 ℃ of surveys), be cooled to room temperature; Learn from else's experience and pulverize the Icing Sugar 400g-600g that 80 mesh sieves are crossed in the back, cross the dextrin 300g-500g of 120 mesh sieves, put mixing in the blender, under agitation add extractum, continue to stir into soft material, granulate through 14 mesh sieves, granule is in 60-70 ℃ of aeration-drying, dry grain removes micro-fine powder with 40 mesh sieves sieve behind 12 mesh sieve granulate, make 1000g lactogenic granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01127576 CN1236800C (en) | 2001-10-31 | 2001-10-31 | Galactic medicine and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01127576 CN1236800C (en) | 2001-10-31 | 2001-10-31 | Galactic medicine and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1416830A true CN1416830A (en) | 2003-05-14 |
| CN1236800C CN1236800C (en) | 2006-01-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01127576 Expired - Fee Related CN1236800C (en) | 2001-10-31 | 2001-10-31 | Galactic medicine and its prepn |
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| Country | Link |
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| CN (1) | CN1236800C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100431584C (en) * | 2006-11-15 | 2008-11-12 | 北京万寿通医药科技有限公司 | Chinese medicinal formulation for caring and enlarging breast |
| CN101077384B (en) * | 2006-05-25 | 2010-06-23 | 高尚先 | Application of traditional Chinese medicine preparation in preparing medicine for treating and preventing gynaecologic disease |
| CN101073643B (en) * | 2006-05-19 | 2010-06-23 | 高尚先 | Chinese-medicinal preparation for preventing and treating hypogalactias and and gynecopathy, its production and use |
| CN101502582B (en) * | 2009-03-06 | 2011-02-09 | 段春英 | Composition for eliminating stagnation and promoting lactation and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009062338A1 (en) * | 2007-11-14 | 2009-05-22 | Shangxian Gao | A lactogenic chinese medicine for treatment and prevention of gynecopathy, methods of preparation and uses thereof |
-
2001
- 2001-10-31 CN CN 01127576 patent/CN1236800C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073643B (en) * | 2006-05-19 | 2010-06-23 | 高尚先 | Chinese-medicinal preparation for preventing and treating hypogalactias and and gynecopathy, its production and use |
| CN101077384B (en) * | 2006-05-25 | 2010-06-23 | 高尚先 | Application of traditional Chinese medicine preparation in preparing medicine for treating and preventing gynaecologic disease |
| CN100431584C (en) * | 2006-11-15 | 2008-11-12 | 北京万寿通医药科技有限公司 | Chinese medicinal formulation for caring and enlarging breast |
| CN101502582B (en) * | 2009-03-06 | 2011-02-09 | 段春英 | Composition for eliminating stagnation and promoting lactation and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1236800C (en) | 2006-01-18 |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| ASS | Succession or assignment of patent right |
Owner name: GAO SHANGXIAN Free format text: FORMER OWNER: QINGDAO HIGH-TECH INDUSTRY PARK HUACHEN ENGINEERING CO., LTD. Effective date: 20041022 Owner name: QINGDAO HIGH-TECH INDUSTRY PARK HUACHEN ENGINEERI Free format text: FORMER OWNER: BANGBU FENGYUAN MEDICINE SCI-TECH DEVELOPMENT CO., LTD. Effective date: 20041022 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20041022 Address after: 100077 Beijing city Fengtai District North Hospital No. 8 Building No. 3 room 402 Applicant after: Gao Shangxian Address before: 266101 hi tech Industrial Park, Qingdao Applicant before: Qingdao hi tech Industrial Park Huachen Engineering Co.,Ltd. Effective date of registration: 20041022 Address after: 266101 hi tech Industrial Park, Qingdao Applicant after: Qingdao hi tech Industrial Park Huachen Engineering Co.,Ltd. Address before: 233010 No. 73, Daqing Road, Bengbu, Anhui Applicant before: BENGBU BBCA MEDICINE SCIENCE & DEVELOPMENT Co.,Ltd. |
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| ASS | Succession or assignment of patent right |
Owner name: GAO SHANGXIAN Free format text: FORMER OWNER: QINGDAO HIGH SCIENCE INDUSTRIAL PARK HUACHEN BIOLOGY ENGINEERING CO., LTD. Effective date: 20041231 |
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Effective date of registration: 20041231 Address after: 100077 Beijing city Fengtai District North Hospital No. 8 Building No. 3 room 402 Applicant after: Gao Shangxian Address before: 266101 hi tech Industrial Park, Qingdao Applicant before: Qingdao hi tech Industrial Park Huachen Biological Engineering Co.,Ltd. |
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| C14 | Grant of patent or utility model | ||
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Granted publication date: 20060118 Termination date: 20181031 |