CN109200250A - A kind of Chinese medicine composition and preparation method thereof for treating breast cancer - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating breast cancer Download PDFInfo
- Publication number
- CN109200250A CN109200250A CN201811429751.XA CN201811429751A CN109200250A CN 109200250 A CN109200250 A CN 109200250A CN 201811429751 A CN201811429751 A CN 201811429751A CN 109200250 A CN109200250 A CN 109200250A
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- breast cancer
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- chinese medicine
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Abstract
The present invention provides a kind of Chinese medicine composition for treating breast cancer, and the Chinese medicine composition is acted like a bully monarch drug in a prescription with Radix Angelicae Sinensis, Radix Astragali, Rhizoma Chuanxiong, Radix Curcumae, radix paeoniae rubra, green peel, tangerine seed and member, and monarch drug in a prescription compatibility has the effect of easypro liver smooth spleen；Using cornu cerve degelatinatum, HERBA EPIMEDII, thizoma curculiginis, oyster and rhizoma cyperi as ministerial drug, the effect of ministerial drug plays strong kidney relieve stagnation altogether；Using spina gleditsiae, semen momordicae, stir-baked SQUAMA MANITIS, leech and Eupolyphoge sinensis as adjutant, adjutant softening hard masses knot；It is to make medicine with the stem pith of the rice-paper plant, the root of Chinese clematis, honeysuckle, dandelion, viola mandshurica, the seed of cowherb, fritillaria thunbergii and Prunella vulgaris, makes medicine detumescence detoxification；Radix Glycyrrhizae removing toxic substances, and coordinating the drug actions of a prescription.All medicine compatibilities play the smooth spleen of easypro liver, strong kidney relieve stagnation altogether, with Zhi Qiben；Resolving hard lump, detumescence detoxification, the effect of to control its mark.Simultaneous treatment of principal and subordinate symptoms of the present invention has good effect to treatment breast cancer.
Description
Technical field
The invention belongs to tcm fields, and in particular to a kind of Chinese medicine composition and preparation method thereof for treating breast cancer.
Background technique
Female mammary gland is made of skin, fibr tissue, corpus mamma and fat, and breast cancer is occurred on mammary gland gland
The malignant tumour of skin tissue.Mammary gland is not the vitals for maintaining human life activity, and breast cancer in situ is simultaneously not fatal；But by
The characteristic of normal cell is lost in breast cancer cell, connection is loose between cell, is easy to fall off.Cancer cell once falls off, trip
From cancer cell can send out whole body with blood or lymph, form transfer, threat to life.Breast cancer, which has become, at present threatens female
Property physically and mentally healthy kinds of tumor.With deepening continuously of recognizing breast cancer biological behaviour and the transformation for the treatment of concept
Treatment with update, breast cancer enters complex treatment epoch, forms breast cancer local treatment and controls with what systemic therapy was laid equal stress on
Treatment mode.Doctor can be controlled using operation, radiotherapy, chemotherapy, endocrine as one sees fit according to tumour by stages with the physical condition of patient
The multiple means such as treatment, Biological target therapy and traditional Chinese medicine adjuvant treatment.Diagnosis, by stages and Synthetic of the surgical operation in breast cancer
It is played an important role in treatment.Radiotherapy is the growth that cancer cell is destroyed using radioactive ray, breeding, reaches control and eliminates cancer cell
Effect.Operation, radiotherapy belong to local treatment.Chemotherapy is a kind of application anticancer drug inhibition cancer cell division, is destroyed
The treatment method of cancer cell, abbreviation chemotherapy.Endocrine therapy is to adjust machine using the method for drug or removal endocrinal glands
Internal secreting function, reduces the secretory volume of endocrine hormone, to achieve the purpose that treat breast cancer.Molecular targeted therapy is close
One of research field the most active is that there is the new antitumoral of too many levels mechanism of action to control compared with chemotherapeutics over year
Treat medicine.Chinese traditional treatment tumour is emphasized to adjust the principle with balance, the disease resistance of recovery and enhancing internal body, to reach yin
The purpose of positive balance therapy tumour.Since chemotherapy, endocrine therapy, targeted therapy and traditional Chinese medicine are treated, systemic therapy is belonged to,
And chemotherapy, endocrine therapy, targeted therapy are larger to the side effect of human body, have biggish damage to human body while treating breast cancer
Wound.The compatibility effect that Chinese medicine mainly passes through Chinese medicine is just treated, and the middle medication of the treatment breast cancer in currently available technology
Effect is slow, and medication time is long, and cure rate is difficult to control.
Summary of the invention
For the technical problem more than solving, the present invention provides a kind of Chinese medicine composition for treating breast cancer, the Chinese medicine
Composition carries out compatibility by monarch, and ingredients collaboration plays a role, and effectively improves the effective percentage of breast cancer.
The object of the present invention is to provide a kind of Chinese medicine compositions for treating breast cancer.
It is a further object of the present invention to provide a kind of preparation methods of the Chinese medicine composition of above-mentioned treatment breast cancer.
The Chinese medicine composition of the treatment breast cancer of specific embodiment according to the present invention, the raw material including following parts by weight:
8-12 parts of Radix Angelicae Sinensis, 12-18 parts of Radix Astragali, 8-12 parts of Rhizoma Chuanxiong, 12-18 parts of radix paeoniae rubra, 8-12 parts of green peel, 8-12 parts of tangerine seed,
8-12 parts of Radix Curcumae, 8-12 parts of rhizoma cyperi, 8-12 parts of corydalis tuber, 12-18 parts of the stem pith of the rice-paper plant, 12-18 parts of the root of Chinese clematis, 12-18 parts of honeysuckle, Pu Gong
12-18 parts of English, 12-18 parts of viola mandshurica, 12-18 parts of the seed of cowherb, 25-35 parts of spina gleditsiae, 8-12 parts of semen momordicae, stir-baked SQUAMA MANITIS 8-
12 parts, 8-12 parts of leech, 8-12 parts of Eupolyphoge sinensis, 25-35 parts of cornu cerve degelatinatum, 12-18 parts of HERBA EPIMEDII, 12-18 parts of thizoma curculiginis, oyster 12-18
Part, 12-18 parts of fritillaria thunbergii, 12-18 parts and Radix Glycyrrhizae 8-12 parts of Prunella vulgaris.
It is in swell gradually slowly that Chinese medicine, which thinks carcinoma often, and the symptom of no shoot should belong to negative subcutaneous ulcer scope.And etiology and pathogenesis is prominent
Out, pathologic feature is severe.Thus, should using traditional medicine sweat, spit, under and temperature, mend, the clear, temperature in the eight big therapeutic rules that disappear,
Mend, be clear, disappear four big therapies, and need four methods develop simultaneously, synthesis is treated, and could ensure and disease is answered to play special efficacy to method.
This temperature refers to the scattered carcinoma of temperatureization, temperature.The cold then ice of water then coagulates, and hydro-thermal is then boiled, then changed.Carcinoma, must with high fever it
Medicine could warm dispersion solution.This benefit refers to supplement vigour, it is basic by force, realizes that righting is got rid of evils, adds the purpose for helping the efficacy of a drug.This refers to clearly
It will be cleared out of in vitro by the cancer cell of warm dispersion solution in vivo.This passway that disappears that disappears, makes medicine have route, and heresy has outlet.Only such as
This, is only real effective method for the treatment of cancer.
Breast cancer is mostly unsmooth because of sincerity, causes liver depression, spleen to be stranded, kidney deficiency, and makes female breast physiological mechanism disorder, and qi and blood obtains
Less than normal biochemical, the stasis of blood and agglomerate, be denaturalized at cancer.Chinese medicine composition the matching by all medicines for the treatment of breast cancer provided by the invention
5, the smooth spleen of easypro liver, strong kidney relieve stagnation are played, altogether with Zhi Qiben；Resolving hard lump, detumescence detoxification, to control its mark, the effect of simultaneous treatment of principal and subordinate symptoms,
To have good therapeutic effect to breast cancer.
Preferably, the raw material including following parts by weight:
9-10 parts of Radix Angelicae Sinensis, 14-16 parts of Radix Astragali, 9-10 parts of Rhizoma Chuanxiong, 14-16 parts of radix paeoniae rubra, 9-10 parts of green peel, 9-10 parts of tangerine seed,
9-10 parts of Radix Curcumae, 9-10 parts of rhizoma cyperi, 9-10 parts of corydalis tuber, 14-16 parts of the stem pith of the rice-paper plant, 14-16 parts of the root of Chinese clematis, 14-16 parts of honeysuckle, Pu Gong
14-16 parts of English, 14-16 parts of viola mandshurica, 14-16 parts of the seed of cowherb, 28-32 parts of spina gleditsiae, 9-10 parts of semen momordicae, stir-baked SQUAMA MANITIS 9-
10 parts, 9-10 parts of leech, 9-10 parts of Eupolyphoge sinensis, 28-32 parts of cornu cerve degelatinatum, 14-16 parts of HERBA EPIMEDII, 14-16 parts of thizoma curculiginis, oyster 14-16
Part, 14-16 parts of fritillaria thunbergii, 14-16 parts and Radix Glycyrrhizae 9-10 parts of Prunella vulgaris.
Preferably, the raw material including following parts by weight:
10 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 15 parts of radix paeoniae rubra, 10 parts of green peel, 10 parts of tangerine seed, 10 parts of Radix Curcumae, rhizoma cyperi 10
Part, 10 parts of corydalis tuber, 15 parts of the stem pith of the rice-paper plant, 15 parts of the root of Chinese clematis, 15 parts of honeysuckle, 15 parts of dandelion, 15 parts of viola mandshurica, the seed of cowherb 15
Part, 30 parts of spina gleditsiae, 10 parts of semen momordicae, 10 parts of stir-baked SQUAMA MANITIS, 10 parts of leech, 10 parts of Eupolyphoge sinensis, 30 parts of cornu cerve degelatinatum, 15 parts of HERBA EPIMEDII,
15 parts of thizoma curculiginis, 15 parts of oyster, 15 parts of fritillaria thunbergii, 15 parts and 10 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of the treatment breast cancer of specific embodiment according to the present invention, including following step
It is rapid:
(1) it prepares stir-baked SQUAMA MANITIS: sand is fried to 215-250 DEG C, pangolin piece, stirring frying 6-10min to table is added
Face is heaved, and pangolin piece is taken out, cooling, is washed, dry, obtains stir-baked SQUAMA MANITIS；
(2) it prepares cornu cerve degelatinatum: taking deer horn, be added in 30-50 DEG C of warm water and cook 10-15min, pull out, obtain just making
Deer horn；Then it takes Herba Epimedii to soak in water 2-4h, then squeeze juice, obtains Herba Epimedii juice；Just deer horn processed is crushed, is added to
In Herba Epimedii juice, it is heated to 80-100 DEG C, is cooked by slow fire 1-1.5h, is concentrated, it is dry, obtain cornu cerve degelatinatum；
(3) stir-baked SQUAMA MANITIS that step (1) obtains is weighed, the cornu cerve degelatinatum and remaining raw material that step (2) obtains, mild fire frying
10-15min；Then white wine, frying 30-45min are sprayed in mild fire frying, the weight of the white wine is raw material gross weight
0.1-0.12 times, the concentration of the white wine is 42-52 degree；It is cooling, it crushes, sieving obtains medicinal mixture powder, is then added
Rape flower honey, is made pill, obtains the medicine pill of the treatment breast cancer.
The preparation method of pill of the invention obtains stir-baked SQUAMA MANITIS by processing pangolin piece, promotes the ring two in pangolin piece
The utilization rate of peptide obtains the drug effect that cornu cerve degelatinatum promotes cornu cerve degelatinatum by processing deer horn, improves the utilization of a variety of amino acid in deer horn
Rate, then by secret pelletization after the progress wine toast of stir-baked SQUAMA MANITIS, cornu cerve degelatinatum and surplus stock, so that the effective component of drug obtains sufficiently
Utilization, promoted all medicines synergistic effect effect.
Preferably, it in step (2), takes Herba Epimedii that the water of 1.5-2.5 times of parts by weight is added, impregnates 2-4h.
Preferably, in step (2), the just weight ratio of deer horn processed and Herba Epimedii juice is 1:2-3.
Preferably, in step (3), the partial size of the medicinal mixture powder is 100-400 mesh.Drug provided by the invention
The partial size of mix powder is small, and drug can be absorbed by the body, convenient to take, significant effect.
Preferably, in step (3), the weight ratio of the medicinal mixture powder and rape flower honey is 1:0.15-0.2.
Rape flower honey is soft and moist agreeable to the taste, agreeably sweet, has the effect of antibacterial anti-inflammatory, promote digestion, improve immunity, and viscosity is moderate,
Be conducive to pill, facilitate the shelf-life for extending drug, promote the mouthfeel of drug, the effect of ancillary drug.
The preparation method of the treatment breast cancer of specific embodiment according to the present invention, comprising the following steps: weigh bulk pharmaceutical chemicals
Material is added to the temperature of 2.5-3.5 times of parts by weight as in 35-55 DEG C of warm water, heat-insulation soaking 1.5-2.5h, then intense fire is fried boiling
3-8min turns mild fire, is cooked by slow fire 80-120min, squeezes decoction, and filtering is condensed into cream, obtains in the treatment breast cancer
Ointment agent.
Preferably, the relative density of the paste is 1.15-1.25.
The invention has the benefit that
The Chinese medicine composition for the treatment of breast cancer provided by the invention, with Radix Angelicae Sinensis, Radix Astragali, Rhizoma Chuanxiong, Radix Curcumae, radix paeoniae rubra, green peel, tangerine
Core and member are acted like a bully monarch drug in a prescription, and monarch drug in a prescription compatibility has the effect of easypro liver smooth spleen；Using cornu cerve degelatinatum, HERBA EPIMEDII, thizoma curculiginis, oyster and rhizoma cyperi as minister
The effect of medicine, ministerial drug plays strong kidney relieve stagnation altogether；Using spina gleditsiae, semen momordicae, stir-baked SQUAMA MANITIS, leech and Eupolyphoge sinensis as adjutant, adjutant softening hard masses
Knot；It is to make medicine with the stem pith of the rice-paper plant, the root of Chinese clematis, honeysuckle, dandelion, viola mandshurica, the seed of cowherb, fritillaria thunbergii and Prunella vulgaris, medicine is made to disappear
Swollen detoxification；Radix Glycyrrhizae removing toxic substances, and coordinating the drug actions of a prescription.All medicine compatibilities play the smooth spleen of easypro liver, strong kidney relieve stagnation altogether, with Zhi Qiben；Resolving hard lump disappears
Swollen detoxification, the effect of to control its mark.Simultaneous treatment of principal and subordinate symptoms of the present invention has good effect to treatment breast cancer.
The preparation method for the treatment of breast cancer provided by the invention improves L--L- in pangolin piece by processing pangolin piece
The utilization rate of junket Cyclic dipeptides and D--L- junket Cyclic dipeptides, is conducive to the dissolution of protein in pangolin piece, promotes the suction of human body
It receives, by processing cornu cerve degelatinatum, promotes the pharmacological property of deer horn, then carry out mixing wine with remaining all medicine by the above-mentioned medicinal material cooked
Toast, honey are made ball and obtain pill；Or the mode carrying out being condensed into cream by way of decoction prepares paste making agent.The present invention provides
Preparation method can retain the effective component of drug, the drug effect of drug is promoted, so that drug collaboration plays effect, to breast cancer
With good therapeutic effect.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Every 1 parts by weight in present invention implementation are 1g.
Embodiment 1
The Chinese medicine composition for treating breast cancer, the raw material including following parts by weight:
8 parts of Radix Angelicae Sinensis, 12 parts of Radix Astragali, 8 parts of Rhizoma Chuanxiong, 12 parts of radix paeoniae rubra, 8 parts of green peel, 8 parts of tangerine seed, 8 parts of Radix Curcumae, 8 parts of rhizoma cyperi, member
8 parts recklessly, 12 parts of the stem pith of the rice-paper plant, 12 parts of the root of Chinese clematis, 12 parts of honeysuckle, 12 parts of dandelion, 12 parts of viola mandshurica, 12 parts of the seed of cowherb, soap
25 parts of angle thorn, 8 parts of semen momordicae, 8 parts of stir-baked SQUAMA MANITIS, 8 parts of leech, 8 parts of Eupolyphoge sinensis, 25 parts of cornu cerve degelatinatum, 12 parts of HERBA EPIMEDII, 12 parts of thizoma curculiginis,
12 parts of oyster, 12 parts of fritillaria thunbergii, 12 parts and 8 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of above-mentioned treatment breast cancer, comprising the following steps:
(1) it prepares stir-baked SQUAMA MANITIS: sand is fried to 215 DEG C, be added pangolin piece, stirring frying 10min to cokled surface,
Pangolin piece is taken out, it is cooling, it washs, it is dry, obtain stir-baked SQUAMA MANITIS；
(2) it prepares cornu cerve degelatinatum: taking deer horn, be added in 30 DEG C of warm water and cook 15min, pull out, obtain just deer horn processed；So
It takes Herba Epimedii to add afterwards and impregnates 2h in the water of 1.5 times of parts by weight, then squeeze juice, obtain Herba Epimedii juice；Just deer horn processed is crushed,
It being added in Herba Epimedii juice, the just weight ratio of deer horn processed and Herba Epimedii juice is 1:2,80 DEG C is heated to, 1.5h is cooked by slow fire,
Concentration, it is dry, obtain cornu cerve degelatinatum；
(3) stir-baked SQUAMA MANITIS that step (1) obtains is weighed, the cornu cerve degelatinatum and remaining raw material that step (2) obtains, mild fire frying
Then 10min sprays white wine, frying 30min in mild fire frying, the weight of the white wine is 0.1 times of raw material gross weight, institute
The concentration for stating white wine is 42 degree, cooling, is crushed, and sieving obtains medicinal mixture powder, the partial size of the medicinal mixture powder
For 100-120 mesh, rape flower honey is then added, the weight ratio of the medicinal mixture powder and rape flower honey is 1:
0.15, pill is made, obtains the medicine pill of the treatment breast cancer.
The specification of the medicine pill of above-mentioned treatment breast cancer is 0.2g/ ball, and the method taken is, daily 2 days adult, every time
9-12g is administered at empty stomach sooner or later, feeds after the 60-90min that takes medicine, children's dosage halves.
Embodiment 2
The Chinese medicine composition for treating breast cancer, the raw material including following parts by weight:
12 parts of Radix Angelicae Sinensis, 18 parts of Radix Astragali, 12 parts of Rhizoma Chuanxiong, 18 parts of radix paeoniae rubra, 12 parts of green peel, 12 parts of tangerine seed, 12 parts of Radix Curcumae, rhizoma cyperi 12
Part, 12 parts of corydalis tuber, 18 parts of the stem pith of the rice-paper plant, 18 parts of the root of Chinese clematis, 18 parts of honeysuckle, 18 parts of dandelion, 18 parts of viola mandshurica, the seed of cowherb 18
Part, 35 parts of spina gleditsiae, 12 parts of semen momordicae, 12 parts of stir-baked SQUAMA MANITIS, 12 parts of leech, 12 parts of Eupolyphoge sinensis, 35 parts of cornu cerve degelatinatum, 18 parts of HERBA EPIMEDII,
18 parts of thizoma curculiginis, 18 parts of oyster, 18 parts of fritillaria thunbergii, 18 parts and 12 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of above-mentioned treatment breast cancer, comprising the following steps:
(1) it prepares stir-baked SQUAMA MANITIS: sand is fried to 250 DEG C, be added pangolin piece, stirring frying 6min to cokled surface,
Pangolin piece is taken out, it is cooling, it washs, it is dry, obtain stir-baked SQUAMA MANITIS；
(2) it prepares cornu cerve degelatinatum: taking deer horn, be added in 50 DEG C of warm water and cook 10min, pull out, obtain just deer horn processed；So
The water for taking Herba Epimedii to add 2.5 times of parts by weight afterwards impregnates 4h, and then squeeze juice, obtains Herba Epimedii juice；Just deer horn processed is crushed, is added
Enter into Herba Epimedii juice, be heated to 100 DEG C, be cooked by slow fire 1h, is concentrated, it is dry, obtain cornu cerve degelatinatum；
(3) stir-baked SQUAMA MANITIS that step (1) obtains is weighed, the cornu cerve degelatinatum and remaining raw material that step (2) obtains, mild fire frying
Then 15min sprays white wine, frying 45min in mild fire frying, the weight of the white wine is 0.12 times of raw material gross weight,
The concentration of the white wine is 52 degree, cooling, is crushed, and sieving obtains medicinal mixture powder, the grain of the medicinal mixture powder
Diameter is 325-400 mesh, rape flower honey is then added, the weight of the medicinal mixture powder and rape flower honey is 1:
0.2, pill is made, obtains the medicine pill of the treatment breast cancer.
The specification of the medicine pill of above-mentioned treatment breast cancer is 0.2g/ ball, and the method taken is, daily 2 days adult, every time
9-12g is administered at empty stomach sooner or later, feeds after the 60-90min that takes medicine, children's dosage halves.
Embodiment 3
The Chinese medicine composition for treating breast cancer, the raw material including following parts by weight:
9 parts of Radix Angelicae Sinensis, 14 parts of Radix Astragali, 9 parts of Rhizoma Chuanxiong, 14 parts of radix paeoniae rubra, 9 parts of green peel, 9 parts of tangerine seed, 9 parts of Radix Curcumae, 9 parts of rhizoma cyperi, member
9 parts recklessly, 14 parts of the stem pith of the rice-paper plant, 14 parts of the root of Chinese clematis, 14 parts of honeysuckle, 14 parts of dandelion, 14 parts of viola mandshurica, 14 parts of the seed of cowherb, soap
28 parts of angle thorn, 9 parts of semen momordicae, 9 parts of stir-baked SQUAMA MANITIS, 9 parts of leech, 9 parts of Eupolyphoge sinensis, 28 parts of cornu cerve degelatinatum, 14 parts of HERBA EPIMEDII, 14 parts of thizoma curculiginis,
14 parts of oyster, 14 parts of fritillaria thunbergii, 14 parts and 9 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of above-mentioned treatment breast cancer, the method are as follows: weigh raw medicinal material, be added to
The temperature of 2.5 times of parts by weight is heat-insulation soaking 2.5h in 35 DEG C of warm water, and then intense fire is fried boiling 3min, turns mild fire, is cooked by slow fire
120min squeezes decoction, and filtering is condensed into cream, obtains the Chinese medicinal ointment of the treatment breast cancer, the relative density of the paste
It is 1.15.
The application method of the Chinese medicinal ointment of above-mentioned treatment breast cancer be it is adult 2 times a day, it is early each taking 120-150ml
Evening is administered at empty stomach, and feeds again after 60-90min after medication, and children's dosage halves.
Embodiment 4
The Chinese medicine composition for treating breast cancer, the raw material including following parts by weight:
10 parts of Radix Angelicae Sinensis, 16 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 16 parts of radix paeoniae rubra, 10 parts of green peel, 10 parts of tangerine seed, 10 parts of Radix Curcumae, rhizoma cyperi 10
Part, 10 parts of corydalis tuber, 16 parts of the stem pith of the rice-paper plant, 16 parts of the root of Chinese clematis, 16 parts of honeysuckle, 16 parts of dandelion, 16 parts of viola mandshurica, the seed of cowherb 16
Part, 32 parts of spina gleditsiae, 10 parts of semen momordicae, 10 parts of stir-baked SQUAMA MANITIS, 10 parts of leech, 10 parts of Eupolyphoge sinensis, 32 parts of cornu cerve degelatinatum, 16 parts of HERBA EPIMEDII,
16 parts of thizoma curculiginis, 16 parts of oyster, 16 parts of fritillaria thunbergii, 16 parts and 10 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of above-mentioned treatment breast cancer, the method are as follows: weigh raw medicinal material, be added to
The temperature of 3.5 times of parts by weight is heat-insulation soaking 1.5h in 55 DEG C of warm water, and then intense fire is fried boiling 8min, turns mild fire, is cooked by slow fire
80min squeezes decoction, and filtering is condensed into cream, obtains the Chinese medicinal ointment of the treatment breast cancer, the relative density of the paste
It is 1.25.
The application method of the Chinese medicinal ointment of above-mentioned treatment breast cancer be it is adult 2 times a day, it is early each taking 120-150ml
Evening is administered at empty stomach, and feeds again after 60-90min after medication, and children's dosage halves.
Embodiment 5
The Chinese medicine composition for treating breast cancer, the raw material including following parts by weight:
10 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 15 parts of radix paeoniae rubra, 10 parts of green peel, 10 parts of tangerine seed, 10 parts of Radix Curcumae, rhizoma cyperi 10
Part, 10 parts of corydalis tuber, 15 parts of the stem pith of the rice-paper plant, 15 parts of the root of Chinese clematis, 15 parts of honeysuckle, 15 parts of dandelion, 15 parts of viola mandshurica, the seed of cowherb 15
Part, 30 parts of spina gleditsiae, 10 parts of semen momordicae, 10 parts of stir-baked SQUAMA MANITIS, 10 parts of leech, 10 parts of Eupolyphoge sinensis, 30 parts of cornu cerve degelatinatum, 15 parts of HERBA EPIMEDII,
15 parts of thizoma curculiginis, 15 parts of oyster, 15 parts of fritillaria thunbergii, 15 parts and 10 parts of Radix Glycyrrhizae of Prunella vulgaris.
The preparation method of the Chinese medicine composition of above-mentioned treatment breast cancer, comprising the following steps:
(1) it prepares stir-baked SQUAMA MANITIS: sand is fried to 235 DEG C, be added pangolin piece, stirring frying 8min to cokled surface,
Pangolin piece is taken out, it is cooling, it washs, it is dry, obtain stir-baked SQUAMA MANITIS；
(2) it prepares cornu cerve degelatinatum: taking deer horn, be added in 40 DEG C of warm water and cook 12min, pull out, obtain just deer horn processed；So
The water for taking Herba Epimedii to add 2 times of parts by weight afterwards impregnates 3h, and then squeeze juice, obtains Herba Epimedii juice；Just deer horn processed is crushed, is added
Into Herba Epimedii juice, 85 DEG C are heated to, is cooked by slow fire 1h, is concentrated, it is dry, obtain cornu cerve degelatinatum；
(3) stir-baked SQUAMA MANITIS that step (1) obtains is weighed, the cornu cerve degelatinatum and remaining raw material that step (2) obtains, mild fire frying
Then 15min sprays white wine, frying 45min in mild fire frying, the weight of the white wine is 0.12 times of raw material gross weight,
The concentration of the white wine is 52 degree, cooling, is crushed, and sieving obtains medicinal mixture powder, the grain of the medicinal mixture powder
Diameter is 325-400 mesh, rape flower honey is then added, the weight of the medicinal mixture powder and rape flower honey is 1:
0.2, pill is made, obtains the medicine pill of the treatment breast cancer.
The specification of the medicine pill of above-mentioned treatment breast cancer is 0.2g/ ball, and the method taken is, daily 2 days adult, every time
9-12g is administered at empty stomach sooner or later, feeds after the 60-90min that takes medicine, children's dosage halves.
Test example
It counts between 2008-2018, sees and treat patients and treat 216 people of patient with breast cancer, take treatment mammary gland provided by the invention
The Chinese medicine composition of cancer continuously takes healing and is discontinued.Efficacy assessment standard of the invention are as follows:
Criterion of cure: every physical examination index is normal, and life cycle extends 5 years or more；
Effective standard: more similar patient, clinical manifestation pathology period are elongated, and life quality is obviously improved, life cycle
Extend 1 year or more；
Effective standard: before comparing treatment or situation early period makes moderate progress, and feels symptom and is alleviated, life quality
It makes moderate progress；
Null criterion: clinical symptoms aggravate, and it is essentially identical compared with similar patient that clinic cashes the pathology period.
Above-mentioned patient with breast cancer takes the Chinese medicine composition for the treatment of breast cancer provided by the invention according to doctor's advice, in treatment phase
Between can not sexual intercourse；Medication cannot be interrupted；The anti-pharmacological property such as the marors such as fasting white sugar, green onion, ginger, garlic and white radishes, mung bean
Food, above-mentioned patient is by after taking, wherein cure 121 people of patient, cure rate reaches 56%, effective patient (including cure
Patient) 148 people, obvious effective rate 68.5%；Effective patient (including cure and effective) 162, effective percentage is 75%.
Wherein: cure rate is the percentage for curing patient's number of cases and total patient's number of cases；
Obvious effective rate is the percentage of effective number (patient including healing) and total number of persons；
Effective percentage be efficiently individual quantity (including cure and it is effective) and total number of persons percentage.
It can be seen that the Chinese medicine composition for the treatment of breast cancer provided by the invention to breast cancer from above-mentioned statistical data
Cure rate reaches 56%, and obvious effective rate reaches 68.5%, and effective percentage reaches 75%, can carry out for the morbidity of breast cancer effective
Treatment, it is significant in efficacy.
Typical case
1. Lee, female, 34 years old, Pekinese.In 2010, discovery left breast had lump distending pain, certain hospital is gone to check,
Sampled biopsy, is diagnosed as breast cancer.Leave hospital in institute's surgical resection therapy, and after doing the chemotherapy of 5 courses for the treatment of, at home certainly
Medication object is recuperated.The discovery for example preceding left breast of right breast is similar to symptom after 06 months 1 year, and involves double newborn chests and back
The soft loin addiction pain in portion.It is rechecked by Ru Yuan hospital, is diagnosed as the lower sternal rib of right breast, double creams, right kidney Ca infiltration.It is hospitalized and changes once again
After treating 3 times, hair all falls off, and do not feel like eating, sick body is very weak, and bed cannot take care of oneself, and blood examination hemochrome, blood platelet are low
In minimum, cannot continue to receive chemotherapy.Patient parent has a gleam of hope in arms and seeks medical advice in the present inventor, and use is provided by the invention
The traditional Chinese medicine composition for treating for treating breast cancer.First 7 days, the pill for taking embodiment 5 to provide merged with the paste that embodiment 3 provides
Dosage and adding time is taken, i.e. medication 4 times daily just used the warm paste of 130ml every 6 hours, with taking 9g pill 1 time.Patient
It oneself gets up within 2nd day, search of food is allayed one's hunger, readme when further consultation in the 7th day, just feels that spirit is big good from medication the 3rd day, food stomach is big
It opens, pain is without can take care of oneself.The 8-14 days, daily dosage was constant, and number by being changed to 3 times 4 times a day；The 15-49 days,
It is changed to subtract pill, only takes paste, 3 times a day；The 50-90 days, change and take pill, patient carries, each 9g, 3 times a day.
It is treated through a March, the check of patient Hui Yuan hospital, isotopic examination result is all close to normal value, other indexs are also in normal model
In enclosing.Oneself black hair all over the face of patient, complexion is ruddy, and life is normal.It is back on the job after 6 months, follow-up 5 years without exception.
2. Zhang, female, 44 years old.Patient Mr. Yu tumour hospital, which transfers from one hospital to another, carrys out the present inventor's punishment treatment.Patient cannot walk when coming,
Single rack is sat to be lifted into ward.Original record of being hospitalized is recorded: patient is diagnosed as double newborn cellule breast cancer in March, 2009, and radiotherapy 14 times
The double newborn resection operations of row after invalid, chemotherapy 6 times after continuing, sick body has a delicate constitution, should not chemotherapy again.Turn to control in the present inventor,
Using the traditional Chinese medicine composition for treating for the treatment of breast cancer provided by the invention.First 7 days, the pill for taking the embodiment of the present invention 5 to provide
Merges dosage with the paste that embodiment 3 provides and add and time take, is i.e. medication 4 times daily, every 6 hours, just with 140ml paste temperature
Heat, companion take 9g pill 1 time.It oneself gets up within patient the 4th day, search of food is allayed one's hunger, and readme when further consultation in the 8th day, medication is wanted to eat on the 4th day
Thing just feels that spirit improves from the 5th day, pain is without self-care of getting up in the 7th day.The 8-14 days, daily dosage was constant,
Number by being changed to 3 times 4 times a day；It the 15-49 days, is changed to subtract pill, only takes paste, 3 times a day；The 50-90 days, changes and take ball
Agent, patient carry, each 9g, 3 times a day.It is treated through a March, the check of patient Hui Yuan hospital, isotopic examination result is complete
Portion is close to normal value, other indexs are also in the normal range.The own complexion of patient is ruddy, and life is normal.Follow-up 6 years without exception.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of Chinese medicine composition for treating breast cancer, which is characterized in that the raw material including following parts by weight:
8-12 parts of Radix Angelicae Sinensis, 12-18 parts of Radix Astragali, 8-12 parts of Rhizoma Chuanxiong, 12-18 parts of radix paeoniae rubra, 8-12 parts of green peel, 8-12 parts of tangerine seed, Radix Curcumae
8-12 parts, 8-12 parts of rhizoma cyperi, 8-12 parts of corydalis tuber, 12-18 parts of the stem pith of the rice-paper plant, 12-18 parts of the root of Chinese clematis, 12-18 parts of honeysuckle, dandelion
12-18 parts, 12-18 parts of viola mandshurica, 12-18 parts of the seed of cowherb, 25-35 parts of spina gleditsiae, 8-12 parts of semen momordicae, stir-baked SQUAMA MANITIS 8-12
Part, 8-12 parts of leech, 8-12 parts of Eupolyphoge sinensis, 25-35 parts of cornu cerve degelatinatum, 12-18 parts of HERBA EPIMEDII, 12-18 parts of thizoma curculiginis, 12-18 parts of oyster,
12-18 parts of fritillaria thunbergii, 12-18 parts and Radix Glycyrrhizae 8-12 parts of Prunella vulgaris.
2. the Chinese medicine composition for the treatment of breast cancer according to claim 1, which is characterized in that the original including following parts by weight
Material:
9-10 parts of Radix Angelicae Sinensis, 14-16 parts of Radix Astragali, 9-10 parts of Rhizoma Chuanxiong, 14-16 parts of radix paeoniae rubra, 9-10 parts of green peel, 9-10 parts of tangerine seed, Radix Curcumae
9-10 parts, 9-10 parts of rhizoma cyperi, 9-10 parts of corydalis tuber, 14-16 parts of the stem pith of the rice-paper plant, 14-16 parts of the root of Chinese clematis, 14-16 parts of honeysuckle, dandelion
14-16 parts, 14-16 parts of viola mandshurica, 14-16 parts of the seed of cowherb, 28-32 parts of spina gleditsiae, 9-10 parts of semen momordicae, stir-baked SQUAMA MANITIS 9-10
Part, 9-10 parts of leech, 9-10 parts of Eupolyphoge sinensis, 28-32 parts of cornu cerve degelatinatum, 14-16 parts of HERBA EPIMEDII, 14-16 parts of thizoma curculiginis, 14-16 parts of oyster,
14-16 parts of fritillaria thunbergii, 14-16 parts and Radix Glycyrrhizae 9-10 parts of Prunella vulgaris.
3. the Chinese medicine composition for the treatment of breast cancer according to claim 1, which is characterized in that the original including following parts by weight
Material:
10 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 15 parts of radix paeoniae rubra, 10 parts of green peel, 10 parts of tangerine seed, 10 parts of Radix Curcumae, 10 parts of rhizoma cyperi,
10 parts of corydalis tuber, 15 parts of the stem pith of the rice-paper plant, 15 parts of the root of Chinese clematis, 15 parts of honeysuckle, 15 parts of dandelion, 15 parts of viola mandshurica, 15 parts of the seed of cowherb,
30 parts of spina gleditsiae, 10 parts of semen momordicae, 10 parts of stir-baked SQUAMA MANITIS, 10 parts of leech, 10 parts of Eupolyphoge sinensis, 30 parts of cornu cerve degelatinatum, 15 parts of HERBA EPIMEDII, thizoma curculiginis
15 parts, 15 parts of oyster, 15 parts of fritillaria thunbergii, 15 parts and 10 parts of Radix Glycyrrhizae of Prunella vulgaris.
4. a kind of preparation method of the Chinese medicine composition of any treatment breast cancer of claim 1-3, which is characterized in that packet
Include following steps:
(1) it prepares stir-baked SQUAMA MANITIS: sand is fried to 215-250 DEG C, pangolin piece, stirring frying 6-10min to surface drum is added
It rises, takes out pangolin piece, it is cooling, it washs, it is dry, obtain stir-baked SQUAMA MANITIS；
(2) it prepares cornu cerve degelatinatum: taking deer horn, be added in 30-50 DEG C of warm water and cook 10-15min, pull out, obtain just deer horn processed；
Then it takes Herba Epimedii to soak in water 2-4h, then squeeze juice, obtains Herba Epimedii juice；Just deer horn processed is crushed, excessive sheep is added to
In leaves of pulse plants juice, it is heated to 80-100 DEG C, is cooked by slow fire 1-1.5h, is concentrated, dry, grinding frosts, and obtains cornu cerve degelatinatum；
(3) stir-baked SQUAMA MANITIS that step (1) obtains is weighed, the cornu cerve degelatinatum and remaining raw material that step (2) obtains, mild fire frying 10-
15min；Then white wine, frying 30-45min are sprayed in mild fire frying, the weight of the white wine is the 0.1- of raw material gross weight
0.12 times, the concentration of the white wine is 42-52 degree；It is cooling, it crushes, sieving obtains medicinal mixture powder, rape is then added
Anthophorids honey, is made pill, obtains the medicine pill of the treatment breast cancer.
5. the preparation method of the Chinese medicine composition for the treatment of breast cancer according to claim 4, which is characterized in that step (2)
In, it takes Herba Epimedii that the water of 1.5-2.5 times of parts by weight is added, impregnates 2-4h.
6. the preparation method of the Chinese medicine composition for the treatment of breast cancer according to claim 4, which is characterized in that step (2)
In, the just weight ratio of deer horn processed and Herba Epimedii juice is 1:2-3.
7. the preparation method of the Chinese medicine composition for the treatment of breast cancer according to claim 4, which is characterized in that step (3)
In, the partial size of the medicinal mixture powder is 100-400 mesh.
8. the preparation method of the Chinese medicine composition for the treatment of breast cancer according to claim 4, which is characterized in that step (3)
In, the weight ratio of the medicinal mixture powder and rape flower honey is 1:0.15-0.2.
9. the preparation method of the Chinese medicine composition of any treatment breast cancer of claim 1-3, which is characterized in that including with
Lower step: weighing raw medicinal material, in the warm water that the temperature for being added to 2.5-3.5 times of parts by weight is 35-55 DEG C, heat-insulation soaking 1.5-
2.5h, then intense fire is fried boiling 3-8min, turns mild fire, is cooked by slow fire 80-120min, squeezes decoction, filters, is condensed into cream, obtains
The Chinese medicinal ointment of the treatment breast cancer.
10. the preparation method of the Chinese medicine composition for the treatment of breast cancer according to claim 9, which is characterized in that the cream
The relative density of agent is 1.15-1.25.
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| CN117244035A (en) * | 2023-11-20 | 2023-12-19 | 北京老年医院 | Pharmaceutical composition for treating breast nodules and preparation method thereof |
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Application publication date: 20190115 |