CN1369290A - 益智胶囊 - Google Patents
益智胶囊 Download PDFInfo
- Publication number
- CN1369290A CN1369290A CN 01136349 CN01136349A CN1369290A CN 1369290 A CN1369290 A CN 1369290A CN 01136349 CN01136349 CN 01136349 CN 01136349 A CN01136349 A CN 01136349A CN 1369290 A CN1369290 A CN 1369290A
- Authority
- CN
- China
- Prior art keywords
- oil
- capsule
- seed
- brain
- herba apii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002775 capsule Substances 0.000 title abstract description 7
- 239000008434 yi-zhi Substances 0.000 title abstract 2
- 230000036995 brain health Effects 0.000 title 1
- 239000002994 raw material Substances 0.000 claims description 3
- 238000005728 strengthening Methods 0.000 claims description 2
- 235000004347 Perilla Nutrition 0.000 abstract description 10
- 210000004556 brain Anatomy 0.000 abstract description 7
- 230000006870 function Effects 0.000 abstract description 5
- 244000124853 Perilla frutescens Species 0.000 abstract 1
- 239000001387 apium graveolens Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 description 16
- MBMBGCFOFBJSGT-KUBAVDMBSA-N docosahexaenoic acid Natural products CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 description 10
- 241000229722 Perilla <angiosperm> Species 0.000 description 9
- 235000020669 docosahexaenoic acid Nutrition 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 229960001685 tacrine Drugs 0.000 description 8
- 235000015112 vegetable and seed oil Nutrition 0.000 description 8
- 239000007902 hard capsule Substances 0.000 description 7
- YLJREFDVOIBQDA-UHFFFAOYSA-N tacrine Chemical compound C1=CC=C2C(N)=C(CCCC3)C3=NC2=C1 YLJREFDVOIBQDA-UHFFFAOYSA-N 0.000 description 7
- HJXMNVQARNZTEE-UHFFFAOYSA-N Butylphthalide Chemical compound C1=CC=C2C(CCCC)OC(=O)C2=C1 HJXMNVQARNZTEE-UHFFFAOYSA-N 0.000 description 6
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 235000021323 fish oil Nutrition 0.000 description 4
- 235000013402 health food Nutrition 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 239000007901 soft capsule Substances 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 3
- 229950005197 butylphthalide Drugs 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 229960004488 linolenic acid Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000000653 nervous system Anatomy 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 238000000194 supercritical-fluid extraction Methods 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- ZPIKVDODKLJKIN-NSHDSACASA-N Senkyunolide Chemical compound C1CC=CC2=C1[C@H](CCCC)OC2=O ZPIKVDODKLJKIN-NSHDSACASA-N 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000001351 cycling effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000001525 retina Anatomy 0.000 description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 2
- ACZGCWSMSTYWDQ-UHFFFAOYSA-N 3h-1-benzofuran-2-one Chemical class C1=CC=C2OC(=O)CC2=C1 ACZGCWSMSTYWDQ-UHFFFAOYSA-N 0.000 description 1
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- -1 brain Chemical class 0.000 description 1
- 210000004958 brain cell Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000003727 cerebral blood flow Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 229940090949 docosahexaenoic acid Drugs 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000007087 memory ability Effects 0.000 description 1
- 230000003446 memory effect Effects 0.000 description 1
- 230000006386 memory function Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000004243 retinal function Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- MEYZYGMYMLNUHJ-UHFFFAOYSA-N tunicamycin Natural products CC(C)CCCCCCCCCC=CC(=O)NC1C(O)C(O)C(CC(O)C2OC(C(O)C2O)N3C=CC(=O)NC3=O)OC1OC4OC(CO)C(O)C(O)C4NC(=O)C MEYZYGMYMLNUHJ-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明涉及一种用于健脑、提高记忆的保健品,属于有机化学技术领域。益智胶囊其特征是选用天然植物紫苏子、芹菜子提取的油为主要原料制成,其配比为1∶1。这种新配方及工艺避免了EPA的存在,达到了获取DHA的目的,同时首次在保健食品中加入了含有芹菜甲素(具有改善记忆作用的芹菜子油。克服了当前市场该类产品中含EPA所产生的副作用。
Description
技术领域
一种用于健脑、提高记忆的保健品—益智胶囊，涉及有机化学技术领域。
背景技术
当前市场上具有改善记忆功能的保健食品，大多数产品主要原料为鱼油。鱼油中含有ω-3不饱和脂肪酸，尤其是DHA(是二十二碳六稀酸的英文缩写)，具有软化血管、健脑益智、改善视力的功效，俗称“脑黄金”。EPA(是二十二碳五稀酸的英文缩写)，具有清理血管中的垃圾(胆固醇和甘油三脂)的功能，俗称“血管清道夫”，它是人体所必需的營养物质。人体中的DHA、EPA通常通过新陈代谢转换而来，但婴幼儿和老年人的转换效率低，因此，当人体缺乏时必须从体外摄入，但是价格因素制约了鱼油在我国的普及，另外EPA的缺点是可生成前列腺素，儿童服用过量可能造成性早熟。鱼油中的DHA、EPA同时存在，大量生产时很难分开。
发明内容
为了克服现有技术存在的EPA的副作用，我们设计了益智胶囊的配方。
益智胶囊，其特征是选用天然植物紫苏子、芹菜子提取的油配为主要原料制成，其配比为1∶1。
益智胶囊是将紫苏子和芹菜子粉碎后投入超临界萃取釜中进行加热，设备达到一定温度时，用CO2加压，达到一定压力时，开始循环萃取4小时或5小时后即可得到紫苏子油或芹菜子油，在两种油中分别加入VE密封保存，按上述比例混合均匀，按照软胶囊或硬胶囊的制备方法制成益智软胶囊或益智硬胶囊。
紫苏子油中α—亚麻酸含量高达60％-70％，α—亚麻酸是人体必须脂肪酸，它是体内ω-3系列不饱和脂肪酸的前体。α—亚麻酸经脱饱和酶与碳链延长酶的作用生成一系列代谢产物，其中最主要的是DHA。DHA是大脑、视网膜等神经系统膜磷脂的主要成分，有“脑黄金”之称。DHA在大脑和视网膜等神经系统中含量相当丰富，对维持正常视网膜功能及促进学习行为活动等方面发挥重要作用。紫苏子油能增强记忆功能，重要原因是其能增加神经系统中的DHA的含量，紫苏子油能促进脑内新蛋白质生成，调节脑内单胺类神经递质的水平。
芹菜子油是由芹菜子提取而得，它含有芹菜甲素和芹菜乙素等苯并呋喃酮类化合物。芹菜甲素具有独特的保护脑细胞的功能，具有增强学习记忆的作用，它的这种作用是通过抗脑缺血、改善精神功能缺失、增加局部脑血流量及改善脑能量代谢等途径而发挥。
紫苏子油与芹菜子油均具有改善学习记忆的作用，它们的作用机制有所不同。我们曾对紫苏子油和芹菜子油的混合物促进小鼠及大鼠学习记忆的作用进行了实验，证实二者在改善学习记忆方面具有协同作用，所以选择紫苏子油和芹菜子油的混合物作为益智类保健品，使它们从不同途经发挥改善学习记忆的作用，我们委托中国预防医学科学院营养与食品卫生研究所保健食品功能检验中心对益智胶囊分别进行了动物试验和人体试验见中国预防医学科学院营养与食品卫生研究所保健食品功能检验中心“改善记忆(动物试验)报告”报告编号：营卫功检字第2001-0035号，“改善记忆(人体试验)报告”报告编号：营卫功检字第2001-0035号证实益智胶囊具有改善动物(小鼠)和人体学习记忆的功能。
附图说明
说明书附图，图1是益智软胶囊的工艺流程图，图2是益智硬胶囊的工艺流程图。
具体实施方式
如说明书附图所示，益智胶囊的生产工艺如下：
1、原料油的制备：
将紫苏子粉碎后投入超临界萃取釜中，对萃取釜、解析釜I、解析釜II、贮罐分别进行加热，当上述设备的温度分别达到40℃-45℃、65℃-75℃、55℃-63℃、35℃-40℃时，打开CO2气体瓶，通过压缩泵对前四种设备进行加压，当压力分别达到27Mpa-32Mpa、6Mpa-9Mpa、7Mpa-9Mpa、6Mpa-8Mpa时，开始循环萃取，萃取4小时后，从解析釜I出料口出料，得清彻透明油样物质，加少量的VE，密封保存。
将芹菜子粉碎后同上法超临界萃取，萃取压力为18Mpa-23Mpa、温度为32℃-37℃，萃取5小时，得浅黄色半透明油样物质，加少量VE，密封保存。
将上述二种油状物混合均匀配比：紫苏子油∶芹菜子油＝1∶1。从混合油样工序开始至成品包装各工序均要求在10万级净化车间里操作。
2、软胶囊的制备：
(1)化胶：在化胶罐内加入去离子水、甘油，加热至70℃-80℃，再加入一定比例的明胶、尼泊金，不断搅拌，溶胶约1小时，抽真空，除尽气泡。
(2)压丸：将紫苏子、芹菜子油状物混合均匀，通过软胶囊制丸机进行压丸。
(3)定型：用滚筒定型4小时-6小时。
(4)干燥：于软胶囊干燥机内干燥8小时-12小时。
(5)选丸：挑拣出不合格的定型丸、空瘪丸。
(6)消毒灭菌：置洒洗机中，95％乙醇清洗。
(7)包装成品：即获得益智软胶囊。
3硬胶囊的制备：
(1)装硬胶囊：将紫苏子油、芹菜子油混合均匀，通过胶囊灌装机灌装入特制硬胶囊中。
(2)封口：在胶囊外壳接口处用封口机封一层膜。
(3)选丸：挑拣出不合格的异型丸、漏油丸、空瘪丸。
(4)包装成品：即获得益智硬胶囊。
这种新配方及工艺避免了EPA的存在，达到了获取DHA的目的。同时首次在保健食品中加入了含有芹菜甲素(具有改善记忆作用)的芹菜子油。
Claims (1)
1 一种用于健脑、提高记忆的益智胶囊，涉及有机化学领域，其特征是选用天然植物紫苏子、芹菜子提取的油为主要原料制成，其配比为1∶1。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011363495A CN1166386C (zh) | 2001-10-11 | 2001-10-11 | 益智胶囊 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011363495A CN1166386C (zh) | 2001-10-11 | 2001-10-11 | 益智胶囊 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1369290A true CN1369290A (zh) | 2002-09-18 |
| CN1166386C CN1166386C (zh) | 2004-09-15 |
Family
ID=4673602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011363495A Expired - Lifetime CN1166386C (zh) | 2001-10-11 | 2001-10-11 | 益智胶囊 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1166386C (zh) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005002568A1 (fr) | 2003-06-20 | 2005-01-13 | Shijiazhuang Pharma. Group Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. | Utilisation de 1-n-butylphtalide pour la prevention ou les traitements de la demence |
| EP1757286A4 (en) * | 2004-06-18 | 2010-02-10 | Shijiazhuang Pharma Group | APPLICATION OF L-N-BUTYLPHTHLIDE IN THE PREVENTION AND TREATMENT OF DEMENTIA |
| CN101940292A (zh) * | 2010-07-26 | 2011-01-12 | 无锡市天赐康生物科技有限公司 | 一种辅助改善记忆功能的保健食品及制备方法 |
| CN103813722A (zh) * | 2011-09-13 | 2014-05-21 | 以瓦伦萨国际营业的美国营养品有限公司 | 富含来源于紫苏种子的必需脂肪酸的植物来源种子提取物：物质组合物、制备方法和用途 |
| US9414620B2 (en) | 2008-04-10 | 2016-08-16 | U.S. Nutraceuticals, LLC | Perilla seed composition |
| US9532965B2 (en) | 2008-04-10 | 2017-01-03 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essentially fatty acids derived from Salvia hispanica L. seed: composition of matter, manufacturing process and use |
| US9610313B2 (en) | 2008-04-10 | 2017-04-04 | U.S. Nutraceuticals | Eye health composition and method using plant derived seed extract rich in essential fatty acids derived from perilla seed and carotenoids |
| CN109106738A (zh) * | 2018-09-12 | 2019-01-01 | 沈阳高名医药科技有限公司 | 一种神经酸组合物及其在神经保护中的应用 |
| CN110025651A (zh) * | 2019-04-02 | 2019-07-19 | 江苏圣典医药科技有限公司 | 一种具有抗衰老作用的复合芹菜籽油自乳化软胶囊及其制备方法 |
-
2001
- 2001-10-11 CN CNB011363495A patent/CN1166386C/zh not_active Expired - Lifetime
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005002568A1 (fr) | 2003-06-20 | 2005-01-13 | Shijiazhuang Pharma. Group Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. | Utilisation de 1-n-butylphtalide pour la prevention ou les traitements de la demence |
| US8552058B2 (en) | 2004-06-18 | 2013-10-08 | CSPC Zhongqi Pharmaceutical Technology (Shijazhuang) Co., Ltd. | Application of L-n-butylphthalide in preventing and treating dementia |
| EP1757286A4 (en) * | 2004-06-18 | 2010-02-10 | Shijiazhuang Pharma Group | APPLICATION OF L-N-BUTYLPHTHLIDE IN THE PREVENTION AND TREATMENT OF DEMENTIA |
| US9511106B2 (en) | 2008-04-10 | 2016-12-06 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essential fatty acids derived from perilla seed: composition of matter, manufacturing process and use |
| US9114142B2 (en) | 2008-04-10 | 2015-08-25 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essential fatty acids derived from perilla seed: composition of matter, manufacturing process and use |
| US9138452B2 (en) | 2008-04-10 | 2015-09-22 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essential fatty acids derived from Perilla seed: composition of matter, manufacturing process and use |
| US9414620B2 (en) | 2008-04-10 | 2016-08-16 | U.S. Nutraceuticals, LLC | Perilla seed composition |
| US9532965B2 (en) | 2008-04-10 | 2017-01-03 | U.S. Nutraceuticals, LLC | Plant derived seed extract rich in essentially fatty acids derived from Salvia hispanica L. seed: composition of matter, manufacturing process and use |
| US9610313B2 (en) | 2008-04-10 | 2017-04-04 | U.S. Nutraceuticals | Eye health composition and method using plant derived seed extract rich in essential fatty acids derived from perilla seed and carotenoids |
| US9770047B2 (en) | 2008-04-10 | 2017-09-26 | U.S. Nutraceuticals, LLC | Perilla seed composition |
| CN101940292B (zh) * | 2010-07-26 | 2012-09-05 | 无锡市天赐康生物科技有限公司 | 一种辅助改善记忆功能的保健食品及其制备方法 |
| CN101940292A (zh) * | 2010-07-26 | 2011-01-12 | 无锡市天赐康生物科技有限公司 | 一种辅助改善记忆功能的保健食品及制备方法 |
| CN103813722A (zh) * | 2011-09-13 | 2014-05-21 | 以瓦伦萨国际营业的美国营养品有限公司 | 富含来源于紫苏种子的必需脂肪酸的植物来源种子提取物：物质组合物、制备方法和用途 |
| CN109106738A (zh) * | 2018-09-12 | 2019-01-01 | 沈阳高名医药科技有限公司 | 一种神经酸组合物及其在神经保护中的应用 |
| CN110025651A (zh) * | 2019-04-02 | 2019-07-19 | 江苏圣典医药科技有限公司 | 一种具有抗衰老作用的复合芹菜籽油自乳化软胶囊及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1166386C (zh) | 2004-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Marsol-Vall et al. | Green technologies for production of oils rich in n-3 polyunsaturated fatty acids from aquatic sources | |
| US4970235A (en) | Medicaments containing of linolenic acid | |
| JP5730989B2 (ja) | 超臨界二酸化炭素の抽出を利用した植物からのオメガ脂肪酸含有抽出物の製造方法 | |
| Zhou et al. | Microwave-assisted extraction of lipids, carotenoids, and other compounds from marine resources | |
| CN1166386C (zh) | 益智胶囊 | |
| CN103783614B (zh) | 一种虾青素苹果醋饮料及其制作方法 | |
| CN103947770B (zh) | 一种有利于视力的天然植物油 | |
| CN102669304A (zh) | 一种富硒茶油及其制备方法 | |
| CN101843336A (zh) | 亚麻油脂肪乳口服溶液、饮料及制造方法 | |
| CN101816444A (zh) | 核桃油脂肪乳口服溶液、饮料及制造方法 | |
| CN103417753A (zh) | 一种具有保护心脑血管作用的植物油组合物及其制备方法与应用 | |
| CN104738627A (zh) | 维生素亚麻籽油复方软胶囊及其制备方法 | |
| CN101816423A (zh) | 紫苏籽油脂肪乳口服溶液、饮料及制造方法 | |
| CN114032259B (zh) | 一种酵母菌的高密度发酵及十六碳烯酸提取方法 | |
| WO2015021631A1 (zh) | 一种黄芪籽粗油、精制油及制备方法与应用 | |
| CN105638934B (zh) | 一种银杏复合食用油 | |
| Jafari et al. | Plant oils rich in essential fatty acids | |
| CN105124566A (zh) | 大鲵油、杜仲籽油和红曲米、山楂果、红茶提取物的混合物软胶囊制备及保健作用 | |
| CN101411499B (zh) | 大蒜、洋葱复合精油与抗氧化剂维生素类复配软胶囊 | |
| CN101869297A (zh) | 复方月见紫苏油脂肪乳口服溶液、饮料及制造方法 | |
| CN103361167B (zh) | 高ω-3脂肪酸及其抗氧化营养油生产的生物制剂及微生物转化技术 | |
| CN104012972A (zh) | 一种含姜黄素组合物的保健胶囊及其制备方法 | |
| CN101869298A (zh) | 复方核桃亚麻油脂肪乳口服溶液、饮料及制造方法 | |
| Younas et al. | Versatile Applications, Challenges, and Future Prospects of Cottonseed Oil | |
| CN103053906B (zh) | 猕猴桃籽油口服乳液的制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20040915 |