CN1348377A - 用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法 - Google Patents

用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法 Download PDF

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Publication number
CN1348377A
CN1348377A CN99816160A CN99816160A CN1348377A CN 1348377 A CN1348377 A CN 1348377A CN 99816160 A CN99816160 A CN 99816160A CN 99816160 A CN99816160 A CN 99816160A CN 1348377 A CN1348377 A CN 1348377A
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CN
China
Prior art keywords
tobramycin
patient
treatment
aerosol
aminoglycoside antibiotics
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Pending
Application number
CN99816160A
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English (en)
Chinese (zh)
Inventor
A·B·蒙哥马利
W·R·贝克
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Novartis Vaccines and Diagnostics Inc
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Chiron Corp
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Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of CN1348377A publication Critical patent/CN1348377A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
CN99816160A 1998-12-17 1999-12-17 用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法 Pending CN1348377A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11298498P 1998-12-17 1998-12-17
US60/112,984 1998-12-17

Publications (1)

Publication Number Publication Date
CN1348377A true CN1348377A (zh) 2002-05-08

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ID=22346930

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99816160A Pending CN1348377A (zh) 1998-12-17 1999-12-17 用气溶胶化的抗生素治疗严重慢性支气管炎(支气管扩张症)的方法

Country Status (15)

Country Link
US (1) US6387886B1 (fr)
EP (1) EP1161247A4 (fr)
JP (1) JP2002532430A (fr)
CN (1) CN1348377A (fr)
AU (1) AU778797B2 (fr)
BR (1) BR9916296A (fr)
CA (1) CA2355775A1 (fr)
CH (1) CH693763A5 (fr)
CZ (1) CZ20012147A3 (fr)
HK (1) HK1043732A1 (fr)
HU (1) HUP0105226A3 (fr)
NO (1) NO328594B1 (fr)
PL (1) PL348812A1 (fr)
SI (1) SI20959A (fr)
WO (1) WO2000035461A1 (fr)

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CN102949379A (zh) * 2012-11-14 2013-03-06 中山大学 硫酸奈替米星吸入粉雾剂及其制备方法
CN104510726A (zh) * 2013-09-27 2015-04-15 张金华 一种用于清洁呼吸道系统的食盐干粉吸入剂

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US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
EP1280520B2 (fr) 2000-05-10 2018-03-21 Novartis AG Poudres a base de phospholipides permettant de distribuer un medicament
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
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US8245708B2 (en) * 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
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CN102949379B (zh) * 2012-11-14 2014-11-05 中山大学 硫酸奈替米星吸入粉雾剂及其制备方法
CN104510726A (zh) * 2013-09-27 2015-04-15 张金华 一种用于清洁呼吸道系统的食盐干粉吸入剂

Also Published As

Publication number Publication date
AU778797B2 (en) 2004-12-23
HK1043732A1 (zh) 2002-09-27
EP1161247A1 (fr) 2001-12-12
US6387886B1 (en) 2002-05-14
JP2002532430A (ja) 2002-10-02
PL348812A1 (en) 2002-06-17
HUP0105226A2 (hu) 2002-04-29
NO20012978L (no) 2001-08-15
NO328594B1 (no) 2010-03-29
CA2355775A1 (fr) 2000-06-22
NO20012978D0 (no) 2001-06-15
AU2370100A (en) 2000-07-03
HUP0105226A3 (en) 2003-03-28
BR9916296A (pt) 2004-06-29
WO2000035461A1 (fr) 2000-06-22
CH693763A5 (de) 2004-01-30
SI20959A (sl) 2003-02-28
EP1161247A4 (fr) 2002-05-15
CZ20012147A3 (cs) 2003-01-15

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