CN1345310A - N－酰基－3,4－脱氢脯氨酸和n－酰基－3,4－脱氢哌啶－2－羧酸衍生物的制备工艺 - Google Patents

N－酰基－3,4－脱氢脯氨酸和n－酰基－3,4－脱氢哌啶－2－羧酸衍生物的制备工艺 Download PDF

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Publication number
CN1345310A
CN1345310A CN00805579A CN00805579A CN1345310A CN 1345310 A CN1345310 A CN 1345310A CN 00805579 A CN00805579 A CN 00805579A CN 00805579 A CN00805579 A CN 00805579A CN 1345310 A CN1345310 A CN 1345310A
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CN
China
Prior art keywords
alkyl
acyl
formula
compound
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00805579A
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English (en)
Chinese (zh)
Inventor
B·夏弗
G·赫尔姆辰
U·卡兹梅尔
S·施莱克
H·斯塔尔
V·沃尔法特
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BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of CN1345310A publication Critical patent/CN1345310A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00805579A 1999-03-26 2000-03-17 N－酰基－3,4－脱氢脯氨酸和n－酰基－3,4－脱氢哌啶－2－羧酸衍生物的制备工艺 Pending CN1345310A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19913699.8 1999-03-26
DE19913699A DE19913699A1 (de) 1999-03-26 1999-03-26 Verfahren zur Herstellung von 3,4-Dihydroprolinen und 3,4-Dehydropiperidinen

Publications (1)

Publication Number Publication Date
CN1345310A true CN1345310A (zh) 2002-04-17

Family

ID=7902464

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00805579A Pending CN1345310A (zh) 1999-03-26 2000-03-17 N－酰基－3,4－脱氢脯氨酸和n－酰基－3,4－脱氢哌啶－2－羧酸衍生物的制备工艺

Country Status (22)

Country Link
US (1) US6579971B1 (enExample)
EP (1) EP1165509B1 (enExample)
JP (1) JP3868210B2 (enExample)
KR (1) KR20010104730A (enExample)
CN (1) CN1345310A (enExample)
AT (1) ATE278665T1 (enExample)
AU (1) AU3962500A (enExample)
BR (1) BR0009330A (enExample)
CA (1) CA2368479C (enExample)
CZ (1) CZ20013456A3 (enExample)
DE (2) DE19913699A1 (enExample)
ES (1) ES2230088T3 (enExample)
HK (1) HK1045156A1 (enExample)
HU (1) HUP0200420A2 (enExample)
IL (1) IL145525A0 (enExample)
MX (1) MXPA01009679A (enExample)
NO (1) NO20014645L (enExample)
RU (1) RU2001129097A (enExample)
TR (1) TR200102747T2 (enExample)
TW (1) TWI276626B (enExample)
WO (1) WO2000058284A1 (enExample)
ZA (1) ZA200107629B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100396666C (zh) * 2005-12-14 2008-06-25 郑州大学 （4s）-1-叔丁氧羰基-4-氨基-l-脯氨酸乙酯及其合成工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
DE59409568D1 (de) 1993-09-09 2000-11-30 Schering Ag Wirkstoffe und gas enthaltende mikropartikel
DE19630082A1 (de) * 1996-07-26 1998-01-29 Basf Ag Verfahren zur Herstellung von 3-Pyrrolin-2-carbonsäure-Derivaten
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
DE19723473A1 (de) * 1997-06-04 1998-12-10 Basf Ag Verfahren zur Herstellung von chiralen 3,4-Didehydroprolinen
AU753196B2 (en) 1998-02-09 2002-10-10 Bracco Research S.A. Targeted delivery of biologically active media

Also Published As

Publication number Publication date
EP1165509B1 (de) 2004-10-06
BR0009330A (pt) 2002-01-08
RU2001129097A (ru) 2004-03-20
NO20014645D0 (no) 2001-09-25
US6579971B1 (en) 2003-06-17
KR20010104730A (ko) 2001-11-26
JP2002540190A (ja) 2002-11-26
DE50008117D1 (de) 2004-11-11
TR200102747T2 (tr) 2002-02-21
CA2368479C (en) 2005-03-01
NO20014645L (no) 2001-09-25
JP3868210B2 (ja) 2007-01-17
IL145525A0 (en) 2002-06-30
AU3962500A (en) 2000-10-16
CA2368479A1 (en) 2000-10-05
ATE278665T1 (de) 2004-10-15
DE19913699A1 (de) 2000-09-28
ES2230088T3 (es) 2005-05-01
TWI276626B (en) 2007-03-21
MXPA01009679A (es) 2002-03-14
WO2000058284A1 (de) 2000-10-05
CZ20013456A3 (cs) 2002-05-15
HK1045156A1 (zh) 2002-11-15
ZA200107629B (en) 2002-09-17
HUP0200420A2 (hu) 2002-05-29
EP1165509A1 (de) 2002-01-02

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