CN1336922A - 促血清脂质减少及抗氧化的吗啉衍生物 - Google Patents

促血清脂质减少及抗氧化的吗啉衍生物 Download PDF

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Publication number
CN1336922A
CN1336922A CN00802766A CN00802766A CN1336922A CN 1336922 A CN1336922 A CN 1336922A CN 00802766 A CN00802766 A CN 00802766A CN 00802766 A CN00802766 A CN 00802766A CN 1336922 A CN1336922 A CN 1336922A
Authority
CN
China
Prior art keywords
compound
derivatives
formula
substituted morpholine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00802766A
Other languages
English (en)
Chinese (zh)
Inventor
M·克里塞利斯
E·莱卡
P·库罗纳其斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elpen SA
Original Assignee
Elpen SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elpen SA filed Critical Elpen SA
Publication of CN1336922A publication Critical patent/CN1336922A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN00802766A 1999-01-14 2000-01-14 促血清脂质减少及抗氧化的吗啉衍生物 Pending CN1336922A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GR99100015 1999-01-14
GR990100015 1999-01-14
GR99100227 1999-07-05
GR990100227 1999-07-05

Publications (1)

Publication Number Publication Date
CN1336922A true CN1336922A (zh) 2002-02-20

Family

ID=26316685

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00802766A Pending CN1336922A (zh) 1999-01-14 2000-01-14 促血清脂质减少及抗氧化的吗啉衍生物

Country Status (8)

Country Link
US (1) US6693192B1 (enExample)
EP (1) EP1140877A1 (enExample)
JP (1) JP2002534516A (enExample)
CN (1) CN1336922A (enExample)
AU (1) AU770267B2 (enExample)
BR (1) BR0007490A (enExample)
CA (1) CA2359476C (enExample)
WO (1) WO2000042030A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102127031A (zh) * 2011-01-17 2011-07-20 江苏江神药物化学有限公司 一种麻黄碱类化合物季胺盐及其合成方法和应用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2567720A1 (en) 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
JP2012501681A (ja) 2008-09-12 2012-01-26 ジェンボールト コーポレイション 生体分子の貯蔵および安定化のためのマトリックスおよび媒体
WO2010121022A1 (en) 2009-04-15 2010-10-21 Research Triangle Institute Monoamine reuptake inhibitors
WO2011146821A2 (en) 2010-05-21 2011-11-24 Research Triangle Institute 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
EP2571858B1 (en) 2010-05-21 2018-06-20 Research Triangle Institute Phenylmorpholines and analogues thereof
GR20100100333A (el) * 2010-06-10 2012-01-31 Αγγελικη Παναγιωτη Κουρουνακη Μορφολινικα παραγωγα υποκατεστημενων διαφαινυλικων ενωσεων

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717560A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Neue 2-hydroxy-morpholine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102127031A (zh) * 2011-01-17 2011-07-20 江苏江神药物化学有限公司 一种麻黄碱类化合物季胺盐及其合成方法和应用

Also Published As

Publication number Publication date
BR0007490A (pt) 2001-10-16
EP1140877A1 (en) 2001-10-10
US6693192B1 (en) 2004-02-17
WO2000042030A1 (en) 2000-07-20
JP2002534516A (ja) 2002-10-15
AU1996000A (en) 2000-08-01
CA2359476C (en) 2006-01-03
CA2359476A1 (en) 2000-07-20
AU770267B2 (en) 2004-02-19

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication