CN1317007C - Pearl detoxifying oral liquid and preparing method tehreof - Google Patents
Pearl detoxifying oral liquid and preparing method tehreof Download PDFInfo
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- CN1317007C CN1317007C CNB2003101011382A CN200310101138A CN1317007C CN 1317007 C CN1317007 C CN 1317007C CN B2003101011382 A CNB2003101011382 A CN B2003101011382A CN 200310101138 A CN200310101138 A CN 200310101138A CN 1317007 C CN1317007 C CN 1317007C
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Abstract
The present invention discloses pearl detoxifying oral liquid and a preparing method thereof. Various diseases of skin itch, acne, pimple, etc. on the head, the face and the skin are common and frequently encountered diseases caused by yin asthenia, endogenous heat, toxic heat and endogenous burning. The oral liquid is prepared from pearl layer powder, tortoise plastron, unprocessed rehmannia root, honeysuckle, glabrous greenbrier rhizome and liquorice root by the present invention, and is used for treating the diseases. 216 clinical tests prove that the present invention can treat acne caused by a lung channel wind-heat syndrome or an intestine and stomach damp-heat syndrome, and wind pruritus and miliaria caused by the wind-heat syndrome. The effective rate of the oral liquid for acne, wind pruritus and miliaria are respectively 86.2%, 89.1% and 100%. The total effective rate of the oral liquid is 90.1%.
Description
Technical field
What the present invention relates to is a kind of nourishing YIN and clearing away heat antidotal pharmaceutical preparation that has, and is the Chinese patent medicine of primary raw material with Margarita, Carapax et Plastrum Testudinis specifically, the invention still further relates to the preparation method of this medicine.
Background technology
Disease on the various women's head-ornaments skins such as skin pruritus, acne, acne is a kind of because of the vehement commonly encountered diseases frequently-occurring disease that causes in interior-heat caused by deficiency of YIN, the pyretic toxicity.For these diseases, present treatment means is to use antihistaminic medicine, salicylic acid esters medicine, ethoxybenzene class medicine is mixed with medicine for external use embrocates, or is prepared into medicine for external use with Chinese medicine and embrocates.As application number be: 01114154.9 Chinese invention patent, the lotion and the production method of treatment skin pruritus are prepared into liquid medicine with Radix Angelicae Sinensis, Fructus Toosendan, Flos Caryophylli, Folium Artemisiae Argyi, Semen Raphani, Alumen, Scolopendra, vinegar exactly, and reuse liquid medicine is embrocated the affected part.Medicine for external use is more effective to skin pruritus, because it is a symptomatic treatment, medicine for external use also is a kind of method of taking stopgap measures but then, takes stopgap measures and does not effect a permanent cure, often easily recurrence, outbreak repeatedly causes sufferings even more serious, if acne on the women's head-ornaments or pruritus use medicine for external use can stay cicatrix, influence the attractive in appearance of face, thereby this is not a kind of ideal method.Using Chinese patent medicine orally taken for curing acne and skin pruritus is a kind of good method.Application number is 00112871.x, respectively be called: a kind of Chinese invention patent application for the treatment of dermopathic medicine and preparation method thereof, a kind of Chinese patent medicine of treatment skin pruritus for oral administration is disclosed exactly, it is made up of 17 flavor Chinese medicines such as Indigo Naturalis, Radix Isatidis, Herba Portulacae, to the drying property skin pruritus is more effective, but skin pruritus due to interior-heat caused by deficiency of YIN and facial remedy of acne are still existed certain deficiency.In addition, find no the report of other orally taken for curing facial acne that interior-heat caused by deficiency of YIN causes and skin pruritus.
Summary of the invention
Purpose of the present invention prepares a kind of treatment exactly because of interior-heat caused by deficiency of YIN in the body, vehement and women's head-ornaments that cause, the medicine of dermatosis in the pyretic toxicity; Another object of the present invention just provides the method for this medicine of preparation.
For achieving the above object, the present invention has taked such measure, and a kind of Margarita Jiedu oral liquid makes this oral liquid raw materials of effective components and is:
Margarita layer powder 7-15 weight portion Carapax et Plastrum Testudinis 1-3.5 weight portion Radix Rehmanniae 6-18 weight portion
Flos Lonicerae 1-3.5 weight portion Rhizoma Smilacis Glabrae 6-18 weight portion
Making this oral liquid raw materials of effective components is:
Margarita layer powder 8-12 weight portion Carapax et Plastrum Testudinis 1-2 weight portion Radix Rehmanniae 8-12 weight portion
Flos Lonicerae 1-2 weight portion Rhizoma Smilacis Glabrae 8-12 weight portion
Making this oral liquid raw materials of effective components is:
Margarita layer powder 10 weight portion Carapax et Plastrum Testudiniss 2 weight portion Radix Rehmanniae 10 weight portions
Flos Lonicerae 2 weight portion Rhizoma Smilacis Glabraes 10 weight portions
Also added Radix Glycyrrhizae 1-3.5 weight portion in the crude drug of the present invention.
Margarita layer powder of the present invention refers to sea water pearls, mussel pearl and their pearl shellfish endoplasm layer and pulverizes the fine powder that forms.
Preparation method of the present invention comprises the steps:
1, gets Flos Lonicerae, Rhizoma Smilacis Glabrae, Radix Rehmanniae and the Radix Glycyrrhizae of above-mentioned weight portion, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated, at the uniform velocity to carry out percolation, the percolate that the 5-10 of collection above-mentioned raw materials weight doubly measures, reclaiming ethanol and being concentrated into above-mentioned raw materials weight ratio percolate weight is 1: 1.2, and it is standby to obtain concentrated solution (1).
2, getting Margarita layer powder, to add distilled water an amount of, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1-1.2, it is standby to obtain concentrated solution (2).
3, get Carapax et Plastrum Testudinis and add water heating and decoct 2-5 time, and collect and merge each time decoction liquor, filtration, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, it is standby to get concentrated solution (3).
4, merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 10-24 hour, filter, filtrate and simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain the present invention of 90-110 part.
Take the present invention of above-mentioned measure, replenishing YIN and removing heat is arranged, removing pathogenic heat from blood and toxic substance from the body removes the nebula effect, can be used for treating acne, skin pruritus, miliaria, furuncle carbuncle, the turbid dim eyesight of order, also can improve looks skin moistening, skin care.This is because deficiency of YIN blood is dry, loses it and supports, then can slightly split by skin, and skin pruritus, order is given birth to cataracta, and is vehement in the pyretic toxicity, stops up the QI and blood that stagnates, and the carbuncle furuncle is grown thickly.And the Margarita layer powder salty in the mouth among the present invention is cold in nature, clearing away heat to improve acuity of vision, and yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and detoxifcation removes nebula, is aided with the Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; The Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone, the reinforcing the heart of nourishing blood; The Flos Lonicerae clearing away heat,cooling blood and removing toxin, Rhizoma Smilacis Glabrae detoxifcation dehumidifying, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, thereby make the present invention that replenishing YIN and removing heat be arranged, the effect of removing pathogenic heat from blood and toxic substance from the body.216 routine clinical trials prove, the present invention is perverse to the powder of wind and heat in the lung meridian card or the intestines and stomach damp-heat syndrome, and the pruritus caused by wind pathogen and the miliaria of wind heat blood-heat syndrome had therapeutical effect, and symptom after taking medicine improves obviously.Effective percentage to acne, pruritus caused by wind pathogen, miliaria is respectively 86.2%, 89.1% and 100%.The total effective rate of three kinds of diseases is 90.1%.
Embodiment
Embodiment 1
Prescription
Margarita layer powder 70 gram Carapax et Plastrum Testudiniss 10 gram Radix Rehmanniae 60 grams
Flos Lonicerae 10 gram Rhizoma Smilacis Glabraes 60 gram Radix Glycyrrhizaes 10 grams
Preparation method
1, extracting honeysuckle, Rhizoma Smilacis Glabrae, Radix Rehmanniae and Radix Glycyrrhizae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated 24 hours, carry out percolation with per minute 1-3 milliliter speed, collect the percolate that the 5-10 of above-mentioned raw materials weight doubly measures, reclaim ethanol and be condensed into the above-mentioned raw materials weight ratio be that 1: 1 concentrated solution (1) is standby.
2, getting Margarita layer powder, to add distilled water an amount of, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1-1.2, it is standby to obtain concentrated solution (2).
3, get Carapax et Plastrum Testudinis processing and turn round and look at little bulk, add the water heating and decoct 5 times, each 1.5-2 hour, collect and merge each time decoction liquor, filter, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, it is standby to get concentrated solution (3).
4, merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 24 hours, filter, filtrate and hot simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain 900 milliliters of part the present invention.
Embodiment 2
Prescription
Margarita layer powder 150 gram Carapax et Plastrum Testudiniss 35 gram Radix Rehmanniae 160 grams
Flos Lonicerae 35 gram Rhizoma Smilacis Glabraes 150 gram Radix Glycyrrhizaes 35 grams
Preparation method:
Preparation method is identical with embodiment 1 preparation method, and obtains 1100 milliliters of the present invention.
Embodiment 3
Prescription
Margarita layer powder 100 gram Carapax et Plastrum Testudiniss 20 gram Radix Rehmanniae 100 grams
Flos Lonicerae 20 gram Rhizoma Smilacis Glabraes 100 gram Radix Glycyrrhizaes 20 grams
Preparation method:
Preparation method is identical with embodiment 1 preparation method, and obtains 1000 milliliters of the present invention.
Embodiment 4
Prescription
Margarita layer powder 70 gram Carapax et Plastrum Testudiniss 10 gram Radix Rehmanniae 60 grams
Flos Lonicerae 10 gram Rhizoma Smilacis Glabraes 60 grams
Preparation method
1, extracting honeysuckle, Rhizoma Smilacis Glabrae and Radix Rehmanniae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated 24 hours, carry out percolation with per minute 1-3 milliliter speed, collect the percolate that the 5-10 of above-mentioned raw materials weight doubly measures, reclaim ethanol and be condensed into the above-mentioned raw materials weight ratio be that 1: 1 concentrated solution (1) is standby.
2, all the other preparation methoies are identical with embodiment 1 method, and obtain 900 milliliters of the present invention.
Claims (5)
1, a kind of Margarita Jiedu oral liquid is characterized in that making this oral liquid raw materials of effective components and is:
Margarita layer powder 7-15 weight portion Carapax et Plastrum Testudinis 1-3.5 weight portion Radix Rehmanniae 6-18 weight portion
Flos Lonicerae 1-3.5 weight portion Rhizoma Smilacis Glabrae 6-18 weight portion.
2, oral liquid according to claim 1 is characterized in that making this oral liquid raw materials of effective components and is:
Margarita layer powder 8-12 weight portion Carapax et Plastrum Testudinis 1-2 weight portion Radix Rehmanniae 8-12 weight portion
Flos Lonicerae 1-2 weight portion Rhizoma Smilacis Glabrae 8-12 weight portion.
3, oral liquid according to claim 1 is characterized in that making this oral liquid raw materials of effective components and is:
Margarita layer powder 10 weight portion Carapax et Plastrum Testudiniss 2 weight portion Radix Rehmanniae 10 weight portions
Flos Lonicerae 2 weight portion Rhizoma Smilacis Glabraes 10 weight portions.
4,, it is characterized in that also having added in the crude drug Radix Glycyrrhizae 1-3.5 weight portion according to claim 1,2 or 3 described oral liquids.
5, the preparation method of the described a kind of Margarita Jiedu oral liquid of claim 4 is characterized in that described method comprises the steps:
1. extracting honeysuckle, Rhizoma Smilacis Glabrae, Radix Rehmanniae and Radix Glycyrrhizae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated, at the uniform velocity to carry out percolation, the percolate that the 5-10 of collection above-mentioned raw materials weight doubly measures, reclaiming ethanol and being concentrated into above-mentioned raw materials weight ratio percolate weight is 1: 1.2, and it is standby to get concentrated solution (1);
2. it is an amount of to get Margarita layer powder adding distilled water, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1.2, and it is standby to obtain concentrated solution (2);
3. get Carapax et Plastrum Testudinis and add water heating decoction 2-5 time, and collect each time of merging decoction liquor, filter, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, and it is standby to obtain concentrated solution (3);
4. merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 10-24 hour, filter, filtrate and simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain the described Margarita Jiedu oral liquid of 90-110 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101011382A CN1317007C (en) | 2003-10-17 | 2003-10-17 | Pearl detoxifying oral liquid and preparing method tehreof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101011382A CN1317007C (en) | 2003-10-17 | 2003-10-17 | Pearl detoxifying oral liquid and preparing method tehreof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1528401A CN1528401A (en) | 2004-09-15 |
| CN1317007C true CN1317007C (en) | 2007-05-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2003101011382A Expired - Fee Related CN1317007C (en) | 2003-10-17 | 2003-10-17 | Pearl detoxifying oral liquid and preparing method tehreof |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101336971B (en) * | 2008-06-06 | 2011-09-21 | 孙瑞龙 | Oral traditional Chinese medicine for treating milium |
| CN105833079A (en) * | 2016-05-05 | 2016-08-10 | 宋云飞 | Drug for treating wind itching |
| CN114081908A (en) * | 2021-10-20 | 2022-02-25 | 湖南省开元博物馆 | Antipruritic composition, application thereof and external antipruritic |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1321498A (en) * | 2001-04-28 | 2001-11-14 | 周美妮 | Medicine for curing acne and sore |
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2003
- 2003-10-17 CN CNB2003101011382A patent/CN1317007C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1321498A (en) * | 2001-04-28 | 2001-11-14 | 周美妮 | Medicine for curing acne and sore |
Non-Patent Citations (1)
| Title |
|---|
| 方珍珠暗疮片 东医学，第7卷第4期 1986 * |
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| CN1528401A (en) | 2004-09-15 |
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Effective date of registration: 20120229 Address after: Qinzhou city the Guangxi Zhuang Autonomous Region 535000 min Street No. 76 Patentee after: GUANGXI HEBABIZ PHARMACEUTICAL Co.,Ltd. Address before: 535000 No. 75 Qinzhou Bay Road, the Guangxi Zhuang Autonomous Region, Qinzhou Patentee before: Guangxi Banzhou Pharmaceutical Co.,Ltd. |
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Effective date of registration: 20160218 Address after: 535008, Ma 1 Street, Qinzhou Industrial Park, Qinzhou, the Guangxi Zhuang Autonomous Region Patentee after: GUANGXI HEBABIZ PHARMACEUTICAL TECHNOLOGY Co.,Ltd. Address before: Qinzhou city the Guangxi Zhuang Autonomous Region 535000 min Street No. 76 Patentee before: GUANGXI HEBABIZ PHARMACEUTICAL Co.,Ltd. |
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