CN1060214A - The preparation method of kidney and relieve asthma Chinese medicine patent medicine - Google Patents
The preparation method of kidney and relieve asthma Chinese medicine patent medicine Download PDFInfo
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- CN1060214A CN1060214A CN 91107259 CN91107259A CN1060214A CN 1060214 A CN1060214 A CN 1060214A CN 91107259 CN91107259 CN 91107259 CN 91107259 A CN91107259 A CN 91107259A CN 1060214 A CN1060214 A CN 1060214A
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- aconiti lateralis
- radix rehmanniae
- lateralis preparata
- preparata
- radix
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Abstract
A kind of preparation method that can prevent and treat the Chinese medicine patent medicine of chronic bronchial cough with asthma effectively, adopting crude drug Radix Aconiti Lateralis Preparata, the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Psoraleae, Herba Epimedii, Semen Cuscutae, Pericarpium Citri Reticulatae and Rhizoma Dioscoreae powder is raw material, earlier Radix Aconiti Lateralis Preparata is decocted separately, again the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Psoraleae, Herba Epimedii, Semen Cuscutae, Pericarpium Citri Reticulatae and Radix Aconiti Lateralis Preparata are mixed together decoction, after the merging of each time decocting liquid, filtering and concentrate, add Rhizoma Dioscoreae powder and make extractum, this extract dry, pulverizing are formed.
Description
The invention belongs to the manufacture method of medicine.
Bronchial asthma is a kind of commonly encountered diseases, frequently-occurring disease, and the patient is very painful.The Chinese patent medicine of producing at present as " ERMUNINGSOU WAN ", how can not fundamentally be treated it, so therapeutic effect is very not remarkable.
The manufacture method that the purpose of this invention is to provide a kind of eutherapeutic bronchial asthma medicine.
Manufacture method of medicine of the present invention is a kind of manufacture method with Chinese medicine patent medicine of kidney and relieve asthma effect.This method is that crude drug Radix Aconiti Lateralis Preparata 0.1-11.0%, Radix Rehmanniae 0.5-18.4%, Radix Rehmanniae Preparata 0.5-18.4%, Fructus Psoraleae 0.5-18.4%, Semen Cuscutae 0.5-18.4%, Herba Epimedii 0.1-18.4%, Pericarpium Citri Reticulatae 0.5-5.5%, the Rhizoma Dioscoreae powder 3.6-16.5% that employing is processed through conventional big gun is raw material.After earlier Radix Aconiti Lateralis Preparata being used water boil 1.5-3 hour separately, again Radix Rehmanniae Radix Rehmanniae Preparata, Fructus Psoraleae, Semen Cuscutae, Herba Epimedii, Pericarpium Citri Reticulatae are mixed decoction with Radix Aconiti Lateralis Preparata.Mix the number of times that decocts and be at least 2 times, each boiling time 1.5-4 hour, the water yield of each time decoction was can flood medicine degree of being all the time in the decoction process.Merge, filter and be condensed into thick paste decoct the medicinal liquid of extracting out the back that finishes at every turn, add Rhizoma Dioscoreae powder again and make extractum,, and then make powdery or granular patent medicine this extractum conventional drying, pulverizing.
Powdery that this method is made or granular patent medicine can further be processed into capsule by incapsulating, and also can make sugar coated tablet through tabletting, coating, also can prepare the electuary method routinely and make electuary.
The Chinese medicine patent medicine that this method is made is pitchy, and bitter in the mouth, little sweet has the effect of kidney warming and yang invigorating, can be used for preventing the seasonality outbreak and the chronic bronchitis cough with asthma of bronchial asthma, and its therapeutic effect obviously is better than existing similar Chinese patent medicine.
Manufacture method of the present invention further specifies by following examples.
Subordinate list 1 is the prescription that embodiment 1-7 is adopted.
Embodiment 1:
Adopt subordinate list 1 listed prescription, earlier Radix Aconiti Lateralis Preparata is inserted and decoct in the pond, add suitable quantity of water (to flood) and boil to little and boil, hold and boil 1.5 hours, again Rhizoma Dioscoreae powder 80 grams and all the other medical materials are put into the decoction pond to powder degree of being, decoct with water secondary, hold at every turn and boil 2 hours, then gradation being filtered that the decoction liquor obtain merges, filters and be condensed into proportion is 1.36(80 ℃) thick paste, add Rhizoma Dioscoreae fine powder 100 grams again, make extractum through stirring and evenly mixing, to getting about 250 grams of dry extract behind this extract dry.To be Chinese medicine patent medicine after the dry extract pulverizing with kidney and relieve asthma function.In the present embodiment, further the dry extract after pulverizing is processed.After promptly allowing dry extract cross the 30-60 mesh sieve, be placed in the blender, add the water stirring and make soft material, in granulator, granulate, under 40-75 ℃ of condition, dry by the fire to water content 2-6% with the 12-18 mesh sieve.Again granule is placed granulator with 12-18 mesh sieve granulate, add 7.5 gram Pulvis Talci, stir,, get 1000 (every 0.25 gram) control anti-tussive and-asthmatic medicines then through the tablet machine tabletting.
Embodiment 2:
Adopt subordinate list 1 listed prescription, the time of boiling of holding that Radix Aconiti Lateralis Preparata decocts separately is 2 hours, Radix Aconiti Lateralis Preparata mixes the time that decocts with the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Psoraleae, Semen Cuscutae, Herba Epimedii, Pericarpium Citri Reticulatae be each 2.5 hours, mix and do not add Rhizoma Dioscoreae powder when decocting, decoction liquor merges, concentrates back adding Rhizoma Dioscoreae powder 61.2 and restrains into extractum, all the other steps and the parameter of pharmacy are identical with embodiment 1, make 700 in tablet (every 0.25 gram) at last.
Embodiment 3:
Adopt subordinate list 1 listed prescription, the time of boiling of holding that Radix Aconiti Lateralis Preparata decocts separately is 2.5 hours, Radix Aconiti Lateralis Preparata mixes the time that decocts with all the other medical materials be each 1.5 hours, mix and add Rhizoma Dioscoreae powder 54.2 grams when decocting, decoction liquor merges, concentrates back adding Rhizoma Dioscoreae powder 90 and restrains into extractum, all the other steps and the parameter of pharmacy are identical with embodiment 1, make 800 in tablet (every 0.25 gram) at last.
Embodiment 5:
Adopt subordinate list 1 listed prescription, the time of boiling of holding that Radix Aconiti Lateralis Preparata decocts separately is 1.5 hours, Radix Aconiti Lateralis Preparata mixes the time of boiling of holding that decocts with all the other medical materials be each 3 hours, mix and do not add Rhizoma Dioscoreae powder when decocting, decoction liquor merges, concentrates back adding Rhizoma Dioscoreae powder 40.2 and restrains into extractum, all the other steps of pharmacy are poly-and parameter is identical with embodiment 1, make 500 in tablet (every 0.25 gram) at last.
Embodiment 6:
Adopt subordinate list 1 listed prescription, the time of boiling of holding that Radix Aconiti Lateralis Preparata decocts separately is 1.5 hours, Radix Aconiti Lateralis Preparata mixes the time of boiling of holding that decocts with all the other medical materials be each 4 hours, mix and add Rhizoma Dioscoreae powder 31.2 grams when decocting, the decoction liquor merging concentrates, the back adds Rhizoma Dioscoreae powder 70 and restrains into extractum, all the other steps and the parameter of pharmacy are identical with embodiment 1, make 700 in tablet (every 0.25 gram) at last.
Embodiment 7:
Adopt subordinate list 1 listed prescription, the time of boiling of holding that Radix Aconiti Lateralis Preparata decocts separately is 1.5 hours, Radix Aconiti Lateralis Preparata mixes decoction three times with all the other medical materials, hold the 1.5 hours time of boiling at every turn, mix and add Rhizoma Dioscoreae powder 51.2 grams when decocting, decoction liquor merges, concentrates back adding Rhizoma Dioscoreae powder 90 and restrains into extractum, and all the other steps and the parameter of pharmacy are identical with embodiment 1, makes 900 in tablet (every 0.25 gram) at last.
The Chinese medicine patent medicine quality that adopts the inventive method to make is stable, safe and reliable.For example the patent medicine through embodiment 5 is produced carries out stability test, gets result of the test such as subordinate list 2.
The Chinese patent medicine that the inventive method is produced has better curative effect for seasonality outbreak and the chronic bronchitis cough with asthma of preventing and treating the bronchus cough with asthma, and has prevention effect at a specified future date, and non-toxic reaction.Patent medicine and the existing Chinese patent medicine " ERMUNINGSOU WAN " produced with embodiment 5 carry out the clinical treatment contrast test, the detail of clinical treatment contrast test such as following.
The treatment group: 90 examples, take the patent medicine that embodiment 5 produces.
Contrast groups: 30 examples, take ERMUNINGSOU WAN.
Patient in two groups adopts the double blind random grouping.Chronic bronchitis is a cardinal symptom to cough, to cough up phlegm with panting, and annual morbidity continues three months at least, and continuous more than 2 years, pulmonary's audible and wheezing sound person.Eliminating has cough with asthma, patient's (as pulmonary tuberculosis, pulmonary abscess, bronchiectasis, heart disease etc.) of the symptom of coughing up phlegm, pant other disease in addition.Except carrying out general physical examination, also made lab testing: hematuria routine, liver, renal function, chest X-ray before and after the treatment.Compare before and after the treatment, observe the variation of degree, sputum characteristic and the amount of expectoration of cough with asthma, the symptom of panting.
Each criterion of therapeutical effect is formulated as follows:
1, clinical cure: cough, expectorant, asthma shape and pulmonary's wheezing sound be slight person, or cough, expectorant, asthma shape takes a turn for the better more than ninety percent.
2, produce effects: cough, expectorant, asthma shape and pulmonary's wheezing sound be clearly better.
3, take a turn for the better: cough, expectorant, asthma shape takes a turn for the better more than three one-tenth, or pulmonary's wheezing sound take a favorable turn.
4, invalid: cough, expectorant, asthma shape and wheezing sound do not have and change or take a turn for the better less than three one-tenth persons, and symptom and the wheezing sound person of increasing the weight of.
The result of the test of clinical treatment contrast test such as subordinate list 3.
Claims (1)
1, a kind of preparation method of kidney and relieve asthma Chinese medicine patent medicine, it is characterized in that adopting crude drug Radix Aconiti Lateralis Preparata 0.1-11.0% through conventional big gun moxibustion, Radix Rehmanniae 0.5-18.4%, Radix Rehmanniae Preparata 0.5-18.4%, Fructus Psoraleae 0.5-18.4%, Semen Cuscutae 0.5-18.4%, Herba Epimedii 0.1-18.4%, Pericarpium Citri Reticulatae 0.5-5.5%, Rhizoma Dioscoreae powder 3.6-16.5% is a raw material, after earlier Radix Aconiti Lateralis Preparata being used water boil 1.5-3 hour separately, again with the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Psoraleae, Semen Cuscutae, Herba Epimedii, Pericarpium Citri Reticulatae mixes decoction with Radix Aconiti Lateralis Preparata, mixing the number of times that decocts is at least 2 times, each boiling time 1.5-4 hour, the water yield of each time decoction is can flood medicine degree of being all the time in the decoction process, merge decoct the medicinal liquid of extracting out the back that finishes at every turn, filter and be condensed into thick paste, add Rhizoma Dioscoreae powder again and make extractum, to this extractum conventional drying, pulverizing forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91107259 CN1033210C (en) | 1991-07-27 | 1991-07-27 | Process for preparing Chinese medicine to reinforce vital energy of kidney and relieve asthma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91107259 CN1033210C (en) | 1991-07-27 | 1991-07-27 | Process for preparing Chinese medicine to reinforce vital energy of kidney and relieve asthma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1060214A true CN1060214A (en) | 1992-04-15 |
| CN1033210C CN1033210C (en) | 1996-11-06 |
Family
ID=4908614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 91107259 Expired - Lifetime CN1033210C (en) | 1991-07-27 | 1991-07-27 | Process for preparing Chinese medicine to reinforce vital energy of kidney and relieve asthma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1033210C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102293896A (en) * | 2011-08-26 | 2011-12-28 | 太极集团重庆涪陵制药厂有限公司 | Preparation method of tablet for tonifying kidney and asthma |
| CN103263561A (en) * | 2013-04-27 | 2013-08-28 | 山西医科大学 | Traditional Chinese medicine preparation for treating asthma with kidney-yang deficiency |
| CN104056006A (en) * | 2014-06-23 | 2014-09-24 | 宋克垣 | Drug for treatment of chronic bronchitis and preparation method thereof |
| CN115624586A (en) * | 2022-08-22 | 2023-01-20 | 河南中医药大学第一附属医院 | Traditional Chinese medicine composition for treating hormone-dependent asthma and application thereof |
-
1991
- 1991-07-27 CN CN 91107259 patent/CN1033210C/en not_active Expired - Lifetime
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102293896A (en) * | 2011-08-26 | 2011-12-28 | 太极集团重庆涪陵制药厂有限公司 | Preparation method of tablet for tonifying kidney and asthma |
| CN102293896B (en) * | 2011-08-26 | 2013-04-17 | 太极集团重庆涪陵制药厂有限公司 | Preparation method of tablet for tonifying kidney and controlling asthma |
| CN103263561A (en) * | 2013-04-27 | 2013-08-28 | 山西医科大学 | Traditional Chinese medicine preparation for treating asthma with kidney-yang deficiency |
| CN103263561B (en) * | 2013-04-27 | 2014-10-22 | 山西医科大学 | Traditional Chinese medicine preparation for treating asthma with kidney-yang deficiency |
| CN104056006A (en) * | 2014-06-23 | 2014-09-24 | 宋克垣 | Drug for treatment of chronic bronchitis and preparation method thereof |
| CN115624586A (en) * | 2022-08-22 | 2023-01-20 | 河南中医药大学第一附属医院 | Traditional Chinese medicine composition for treating hormone-dependent asthma and application thereof |
| CN115624586B (en) * | 2022-08-22 | 2023-11-14 | 河南中医药大学第一附属医院 | Traditional Chinese medicine composition for treating hormone-dependent asthma and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1033210C (en) | 1996-11-06 |
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Free format text: CORRECT: PATENTEE; FROM: SICHUAN PEILING PHARMACEUTICAL FACTORY TO: TAIJI GROUP FULING PHARMACEUTICAL FACTORY |
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| CP01 | Change in the name or title of a patent holder |
Patentee after: Taiji Group Fuling Pharmaceutical Factory Patentee before: A satellite tomb Sichuan pharmaceutical factory |
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| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
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Owner name: TAI CHI GROUP CHONGQING FULING PHARMACEUTICAL FACT Free format text: FORMER NAME OR ADDRESS: TAIJI GROUP FULING PHARMACEUTICAL FACTORY |
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Address after: 408000 1 Tai Chi Avenue, Fuling District, Chongqing Patentee after: Taiji Group Chongqing Fuling Pharmaceutical Factory Co., Ltd. Address before: 648000 No. 68, Fuling, Sichuan, Jianshe Road Patentee before: Taiji Group Fuling Pharmaceutical Factory |
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| CX01 | Expiry of patent term |
Expiration termination date: 20110727 Granted publication date: 19961106 |