CN1196953A - Chinese patent drug for treating chronic bronchitis and asthma - Google Patents

Abstract

A Chinese patent medicine for treating chronic bronchitis and asthma is prepared from 12 Chinese-medicinal materials such as ginseng, ephedra, black plum, coltsfoot flower and almond, etc.

Description

A kind of Chinese patent medicine for the treatment of chronic bronchitis, asthma

The present invention relates to a kind of Chinese patent medicine, particularly a kind of Chinese patent medicine for the treatment of chronic bronchitis, asthma.

At present, chronic bronchitis in the vast rural and urban population, pathogenesis of asthma rate are still higher, are frequently-occurring disease, commonly encountered diseases, and the course of disease is long, easily repeatedly, and the asexuality age differences.During special affection of exogenous wind-cold acute attack, patient connects and coughs more than or long difficult breath dormancys of all night must not crouching of breathing heavily, and is unusually painful; Treat the untimely emphysema of will bringing out until pulmonary heart disease, bring bigger misery and burden for patient and family thereof.Up to now, the doctor trained in Western medicine method of treatment is often suited the remedy to the case, oral or instil some antiphlogistic antibacterial class medicine and hormoness are as ephedrine, aminophylline, prednisone etc., though can take effect at that time, temporarily control the state of an illness, but seldom can eradicate, and take the addiction that to bring this medicine for a long time.Though there are several traditional Chinese medicine decoction such as XIAOQINGLONG TANG etc. in the Chinese medicine aspect, adaptive surface is too wide, often because of cure family to the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs of disease improperly also difficulty reach purpose, decocting of special decoction is bothersome time-consuming, takes extremely inconveniently, obstinate disease is dug up the roots from difficulty.

The objective of the invention is to the kidney invigorating, lung benefiting, spleen invigorating, strengthen the physiological function of kidney, spleen, lung, to reach expelling phlegm for arresting cough, antiinflammatory relieving asthma preventing cold and infection, the existing state of an illness is transformed to the recovery from illness direction, can stop tracheitis to emphysema, the development of pulmonary heart disease aspect again, reach the purpose of elimination at last.

Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to chronic bronchitis, asthma mechanism, with reference to modern pharmacological research, select for use relieving asthma class, dampness class medicine of lung benefiting, spleen invigorating, kidney tonifying class, relieving cough and resolving phlegm formulated, can improve human body immune function, improve and to resist climate change and extraneously to infect morbific ability, reach cough-relieving, reduce phlegm, antiinflammatory, relieving asthma, treat the purpose of chronic tracheitis, asthma.

The present invention is formulated by pure Chinese medicine, so human body is had no side effect.

Prescription of the present invention and weight proportion are as follows:

Radix Ginseng 6-12, Herba Ephedrae 8-16, Fructus Mume 8-16, Flos Farfarae 8-16, Semen Armeniacae Amarum 8-16, Fructus Schisandrae Chinensis 8-16, Cortex Cinnamomi 6-12, Radix Stemonae 6-12, Rhizoma Pinelliae 6-10, Rhizoma Zingiberis 6-10, dried Alumen 8-14, Radix Glycyrrhizae 6-12.

After the present invention adopted such scheme, treatment chronic bronchitis, asthma was evident in efficacy, and effective percentage 100%, obvious effective rate 90%, cure rate are more than 75%, and cough and asthma relieving efficacy is rapid, and taking convenience has no side effect.

Below in conjunction with embodiment the present invention is described in detail:

Lung benefiting, spleen invigorating, kidney tonifying class Chinese medicine are among the present invention: Radix Ginseng, Fructus Schisandrae Chinensis, Cortex Cinnamomi, the Rhizoma Pinelliae, the Radix Stemonae, Rhizoma Zingiberis.

The relieving cough and resolving phlegm class Chinese medicine of relievining asthma is: Herba Ephedrae, Semen Armeniacae Amarum, Flos Farfarae, Fructus Mume, the Rhizoma Pinelliae, Radix Glycyrrhizae.

Dampness class Chinese medicine is: the Rhizoma Pinelliae, dried Alumen.

Drug action mechanism of the present invention is as follows:

Radix Ginseng: warm in nature, sweet in the mouth, little hardship; Go into spleen, lung meridian, can strongly invigorating primordial QI, take off admittedly, promote the production of body fluid, calm the nerves.It is short to control deficient, the empty cough with asthma of impairment caused by overstrain; This medicine contains the ginsenoside, and glycoside unit is divided into and contains panaxatriol and panoxadiol's two classes (seeing 29 pages of " Chinese medicine voluminous dictionary " first volumes, the new medical college chief editor in Jiangsu, Shanghai science tech publishing house, in October, 1985 publication).

Flos Farfarae: warm in nature, acrid in the mouth, go into lung meridian, function nourishing the lung to keep the adverse QI downward, antitussive reduces phlegm.Chemical analysis is (the same, 2310 pages of volume two) such as sterols, globulariacitrin, hyperins such as faradiols.

Semen Armeniacae Amarum: warm in nature, bitter in the mouth, poisonous, go into lung meridian, have eliminate the phlegm, cough-relieving, relieving asthma, the function of intestine moistening; Chemical analysis is amygdalin, fatty oil, protein and various free amino acid, and amygdalin is subjected to the hydrolysis of emulsin etc. in the Semen Armeniacae Amarum, can generate hydrocyanic acid (the same, 1100 pages of the first volumes) at last.

Herba Ephedrae: warm in nature, bitter in the mouth is hot, go into lung, urinary bladder channel; The function diaphoresis, relieving asthma, diuretic; Main Ingredients and Appearance has alkaloids such as ephedrine and pseudoephedrine, also (the same, 2221 pages of volume two) such as cellulose glucose, tannins.

Fructus Mume: property is wet, sour in the mouth, goes into liver, spleen, lung, large intestine channel, has convergence to promote the production of body fluid, the dispel function of worm of relieving colic caused by ascaris, fruit contains lemon acid, malic acid, succinic acid etc., contains hydrocyanic acid when ripe, the calm respiratory nerve maincenter of energy plays function of relieving cough and calming asthma (the same, 464 pages of the first volumes).

Fructus Schisandrae Chinensis: warm in nature, sour in the mouth, go into lung, kidney channel, function: astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission, fruit and contain volatile oil, the Sesquicarene., bisabolence etc. (the same, 386 pages of the first volumes) of volume wherein arranged.

Cortex Cinnamomi: hot in nature, acrid in the mouth, sweet, go into kidney, spleen, urinary bladder channel, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation; Skin contains ethereal oil, and Main Ingredients and Appearance is: (the same, 890 pages of the first volumes) such as cinnamic aldehyde, small amount of acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) esters.

The Rhizoma Pinelliae: warm in nature, acrid in the mouth, poisonous, go into taste warp, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Chemical analysis: tuber contains aminoacid (the same, 775 pages of the first volumes) such as ethereal oil, little fat, nicotine, aspartic acid, glutamic acid.

The Radix Stemonae: slightly warm in nature, sweet-bitter flavor, go into lung meridian, gentle lung qi, cough-relieving parasite killing; Composition: root contains multiple alkaloid, and the Radix stemonae japonicae root contains (the same, 860 pages of the first volumes) such as (-)-Stemoninine, protostermonine, stenine alkali.

Rhizoma Zingiberis: hot in nature, acrid in the mouth, go into spleen, stomach, lung meridian; Warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation; Composition: rhizome contains ethereal oil, and (the same, 71 pages of the first volumes) such as zingiberene, phellandrene, gingerol, zingiberol, Borneolum Syntheticum, citric acids wherein arranged.

Dried Alumen: cold in nature, sour in the mouth, puckery, poisonous; Go into lung, spleen, stomach, large intestine channel; Expectorant dampness, antidiarrheal hemostasis, detoxifcation parasite killing; Composition: alkaline potassium aluminum sulfate (the same, 680 pages of the first volumes).

Radix Glycyrrhizae: property is flat, sweet in the mouth, goes into spleen, stomach, lung meridian and middle emergency, lung moistening detoxifcation, coordinating the actions of various ingredients in a prescription; Contained composition: rhizome contains the triterpenoid saponin glycyrrhizic acid, i.e. glycyrrhizin, and multiple flavone; (the same, 568 pages of the first volumes) such as glycyrrhizin, isoliquiritigenins arranged in the composition.

All medicines synthesize lung benefiting, spleen invigorating, kidney tonifying increases immunity of organisms, relieving cough and resolving phlegm, relieving asthma, antiinflammatory, reach the purpose of treatment chronic bronchitis.

Motherland's traditional medicine is thought: earth generating metal, metal generating water, spleen is water for soil, lung for gold, kidney.Be that spleen is that the mother of lung, lung are the mother of kidney, originally be female living son, but female multiplier is arranged that son restrains mother's mechanism.The chronic bronchitis journey is long, easily recurrence, and obstinate then lung is impaired; Then spleen is impaired for factor gram mother; Female multiplier is involved kidney again, shows as so the patients on long-term has a delicate constitution: cloudy, empty, tremble with fear, the resembling of lining.So only dried Alumen is cold in nature simply in all medicines, the property that all the other are all warm; And except that Cortex Cinnamomi, go into lung meridian entirely, have that preventing phlegm from forming and stopping coughing, antiinflammatory are relievingd asthma, an effect of lung moistening, dampness.Go into spleen channel again as Radix Ginseng, the Rhizoma Pinelliae, Radix Glycyrrhizae, Fructus Mume, Cortex Cinnamomi, Rhizoma Zingiberis, the merit of warming the meridian spleen invigorating is arranged.The spleen being the source of producing phlegm is the mother of lung, and disease is the impairment of the spleen then for a long time.Spleen invigorating energy transmitting and distributing the fluids prevents the generation that phlegm retention water overflows; Can transform essence of water and grain again, thus on fail the function of strengthening lung in lung; Have the Fructus Schisandrae Chinensis Cortex Cinnamomi to go into kidney channel again, kidney is a water, and main improving inspiration by invigorating kidney-QI is the son of lung, coughs the deficiency of the lung of a specified duration and then is impairment of the kidney, and is to be female multiplier.Insufficiency of kidney-YANG causes taking the photograph to be received not normally, and then cough with asthma is heavier.Modern medicine study proves, tracheitis and asthma patient all have hypophysis one hypoadrenocorticism symptom, and above medicine has warming the meridian the kidney invigorating effect, but the adrenal cortex reinforcing function, that is improve human body immune function, improve climate change and the morbific ability of extraneous infection resisted.

In sum: the medicine among the present invention, have into lung person, the person that goes into the spleen, the person that goes into the kidney, also have and doublely go into the spleen lung or go into this three through the person, all medicines are each has something to recommend him, coact, reaching the kidney invigorating, lung benefiting, spleen invigorating, the antiinflammatory of relievining asthma, is protected from infection at expelling phlegm for arresting cough, preventing cold, not only controlled but also anti-purpose, thereby chronic bronchitis, asthma are eradicated.

Be the medicine that shows the present invention curative effect, specially 158 these type of patients are made clinical system observe, wherein get medical history, patient's 59 examples that the state of an illness is identical compare group, adopt the doctor trained in Western medicine routine treatment chronic bronchitis, asthma; Get 99 routine patients and be test group, take medicine of the present invention, obey each 1 ball of capsule 6-8 grain or pill every day sooner or later, serve on 3 courses of treatment, the observation period is 6 months.Add up with identical standard at last, criterion of therapeutical effect is:

(1) effective: symptom after taking medicine alleviates or part disappearance person is effectively.

(2) produce effects: symptom after taking medicine greatly alleviates, but not yet all disappearance person be produce effects.

(3) recovery from illness: symptom all disappears after the medication, after 1 year not yet the recidivist for the recovery from illness.

Table 1 matched group curative effect situation:

Table 2 test group curative effect situation:

Embodiment 1: get Radix Ginseng 6g, Herba Ephedrae 8g, Fructus Mume 8g, Flos Farfarae 14g, Semen Armeniacae Amarum 14g, Fructus Schisandrae Chinensis 8g, Cortex Cinnamomi 6g, Radix Stemonae 9g, Rhizoma Pinelliae 6g, Rhizoma Zingiberis 6g, dried Alumen 9g, Radix Glycyrrhizae 6g, wherein Semen Armeniacae Amarum peeling parching to brown is a smalls altogether, incapsulates, every 0.25g sooner or later respectively obeys 6; Or get Mel 100g in addition, and making pellets by mixing medical powder with honey, every ball 3 grams, each oral 1 ball is taken in annual day in the Autumnal Equinox sooner or later, and serveing on for 4 weeks is 1 course of treatment, obeys 3 courses of treatment altogether, cures mainly chronic bronchitis cough weight person.

Embodiment 2: Radix Ginseng 10g, Herba Ephedrae 14g, Fructus Mume 15g, Flos Farfarae 10g, Semen Armeniacae Amarum 10g, Fructus Schisandrae Chinensis 15g, Cortex Cinnamomi 11g, Radix Stemonae 9g, Rhizoma Pinelliae 8g, Rhizoma Zingiberis 8g, dried Alumen 9g, Radix Glycyrrhizae 10g, wherein Semen Armeniacae Amarum peeling parching to brown is a smalls altogether, incapsulates, every 0.25g sooner or later respectively obeys 8; Or get Mel 120g in addition, and making pellets by mixing medical powder with honey, the heavy 3g of every ball, each 1 ball of morning and evening, in day in Autumnal Equinox every year clothes, 28 days is 1 course of treatment, shared 3 courses of treatment, cures mainly chronic trachea, asthma weight person.

Claims (3)

1, the Chinese patent medicine of treatment chronic bronchitis, asthma is characterized in that it is formulated by the following weight proportion raw material: Radix Ginseng 6-12, Herba Ephedrae 8-16, Fructus Mume 8-16, Flos Farfarae 8-16, Semen Armeniacae Amarum 8-16, Fructus Schisandrae Chinensis 8-16, Cortex Cinnamomi 6-12, Radix Stemonae 6-12, Rhizoma Pinelliae 6-10, Rhizoma Zingiberis 6-10, dried Alumen 8-14, Radix Glycyrrhizae 6-12.

2, the Chinese patent medicine of treatment chronic bronchitis according to claim 1, asthma, wherein the weight proportion of each raw material is: Radix Ginseng 6, Herba Ephedrae 8, Fructus Mume 8, Flos Farfarae 14, Semen Armeniacae Amarum 14, Fructus Schisandrae Chinensis 8, Cortex Cinnamomi 8, the Radix Stemonae 9, the Rhizoma Pinelliae 6, Rhizoma Zingiberis 6, dried Alumen 9, Radix Glycyrrhizae 6.

3, the Chinese patent medicine of treatment chronic bronchitis according to claim 1, asthma, wherein the weight proportion of each raw material is: Radix Ginseng 10, Herba Ephedrae 14, Fructus Mume 15, Flos Farfarae 10, Semen Armeniacae Amarum 10, Fructus Schisandrae Chinensis 15, Cortex Cinnamomi 11, the Radix Stemonae 9, the Rhizoma Pinelliae 8, Rhizoma Zingiberis 8, dried Alumen 9, Radix Glycyrrhizae 10.