JPH0733676A - Composition for lowering blood suger value - Google Patents

Composition for lowering blood suger value

Info

Publication number
JPH0733676A
JPH0733676A JP5278857A JP27885793A JPH0733676A JP H0733676 A JPH0733676 A JP H0733676A JP 5278857 A JP5278857 A JP 5278857A JP 27885793 A JP27885793 A JP 27885793A JP H0733676 A JPH0733676 A JP H0733676A
Authority
JP
Japan
Prior art keywords
pts
weight
parts
composition
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5278857A
Other languages
Japanese (ja)
Other versions
JPH0798753B2 (en
Inventor
Bufu Ri
武 夫 李
Daishin Ri
乃 新 李
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RI SOUWA
Original Assignee
RI SOUWA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RI SOUWA filed Critical RI SOUWA
Publication of JPH0733676A publication Critical patent/JPH0733676A/en
Publication of JPH0798753B2 publication Critical patent/JPH0798753B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain a blood glucose level-lowering composition comprising a natural medicine bringing about effect of remarkable lowering of blood glucose level in relatively short period. CONSTITUTION: This composition is composed of powder comprising 50-80 pts.wt. pearl, 120-180 pts.wt. Astragali radix, 120-180 pts.wt. rhizome of Polygonatum sibiricum, 120-180 pts.wt. Trichosanthis radix, 50-80 pts.wt. Ophiopogonis tuber, 50-80 pts.wt. Dendrobii herba, 50-80 pts.wt. Moutan radix cortex, 50-80 pts.wt. Salviae miltiorrhizae radix, 50-80 pts.wt. Tribulus terrestris, 50-80 pts.wt. MANSAN (a perennial vine plant of the family Campanulaceae), 50-80 pts.wt. Galli stomachichum corium and 50-80 pts.wt. Cinnamonomi cortex.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は血糖値降下組成物に関す
るものであり、特に、従来の薬材組成物では到底期待で
きないほどの顕著な血糖値降下の効果を比較的短期間に
得ることのできる血糖値降下剤に関するものである。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood glucose level lowering composition, and in particular, it is possible to obtain a remarkable blood glucose level lowering effect which cannot be expected with conventional pharmaceutical compositions in a relatively short period of time. The present invention relates to a blood glucose lowering agent that can be used.

【0002】[0002]

【従来の技術】糖尿病の予防には食餌療法と体重調節と
が最も重要なものとされており、食餌療法としては高カ
ロリー、高脂肪の食品を過度に多く摂取せずに無機質と
ビタミンを十分に摂取できる飲食物を選択すべきであ
り、特に砂糖をはじめとする炭水化物の摂取を制限しな
ければならないとされている。血液中の血糖量を減少さ
せる漢方薬剤としては麦門冬飲子、四君子湯、大柴胡湯
加地黄、八味丸などが知られているが、麦門冬飲子は、
麦門冬、人参かつ楼根、知母、葛根、地黄、茯苓、五味
子、甘草、竹葉などからなる組成物であって、糖尿病の
他に、体が痩せ、気力が落ち、咳の出る病気、身体虚弱
で咳のひどい慢性気管支炎、肺結核などにも適するよう
に組成されたものであるから、実に糖尿病患者の血糖量
の減少にはこれといった効果をもたらしがたい。
2. Description of the Related Art Diet and weight control are considered to be the most important factors for the prevention of diabetes. As diet, intake of high-calorie and high-fat foods is sufficient and minerals and vitamins are sufficient. Foods and drinks that can be consumed by people should be selected, and intake of carbohydrates such as sugar should be restricted. As Kampo medicines that reduce the blood sugar level in the blood, Bakumondofuinko, Shikunshito, Daisaikoto Kajio, and Hamimaru are known.
It is a composition consisting of Bakumondo, Ginseng and root, Chimoku, Kakkon, ground yellow, 苯 苓, Gomiza, licorice, bamboo leaf, etc. Since it is designed to be suitable for chronic bronchitis, pulmonary tuberculosis, etc., which is physically weak and has a severe cough, it is unlikely to bring such an effect to the reduction of blood glucose level in diabetic patients.

【0003】四君子湯は人参、朮、茯苓、甘草、生姜お
よび大棗などからなる組成物であって、糖尿病の他に胃
腸虚弱症、貧血、夜尿症などにも適するように組成した
ものであり、大柴胡湯加地黄は柴胡、半夏、芍薬、大棗
各、枳実、生姜、大黄、地黄などからなる組成物であっ
て、血糖量の降下以外にも高血圧の治療および体力の充
実に適した薬材であり、八味丸は六味丸、乾地黄、山茱
萸、山薬(やまいもの塊根)、沢潟、茯、牡丹皮、桂
枝、附子などからなる組成物であって、糖尿病の他にも
中風を予防し老人性精神疾患、老人性腰痛、前立腺肥大
症にも用いられる薬材である。
Shikunshi-to is a composition consisting of carrots, sardines, sardines, licorice, ginger, and jujuba, and is also suitable for gastrointestinal weakness, anemia, enuresis, etc. in addition to diabetes. Daisaiko-to-kajio is a composition consisting of saiko, half-summer, peony, daijutsu, kumami, ginger, rhubarb, and ground yellow, and is suitable for treating hypertension and enhancing physical fitness in addition to lowering blood sugar levels. It is a medicinal material, and Hami Gan is a composition consisting of Romi Gan, Dried Yellow, Yamatake, Sanyaku (Yamaimono tuber), Sawagata, Boi, Peony skin, Keishi, Fuzi, etc. Is a drug used to prevent middle-aged illness and is also used for senile psychiatric disorders, senile low back pain, and benign prostatic hyperplasia.

【0004】しかし、これらはすべて血糖量降下剤とし
ての効果が明確でなく、糖尿病患者たちに一般的に利用
されていないのが実情である。
[0004] However, all of them are not clearly effective as hypoglycemic agents and are not generally used in diabetic patients.

【0005】他にも血糖量を減少させ糖尿病を治療する
漢方薬材組成物に対する研究は数多くおこなわれてきた
が、前記処方に若干の変化があっただけで未だにこれと
いった薬剤が開発されていない。一方、いわゆる文明病
と称される糖尿病は日に日に増加し、今や我が社会にお
いて治療の極めて難しい不治の病の一つとして巣くうよ
うになった。
[0005] In addition, many studies have been conducted on Kampo medicine composition for reducing blood glucose level and treating diabetes, but such a drug has not been developed due to a slight change in the prescription. On the other hand, diabetes called so-called civilization has been increasing day by day, and now it has become one of the incurable diseases that are extremely difficult to treat in our society.

【0006】[0006]

【発明が解決しようとする課題】糖尿病は、血液中に溶
けている糖分を各細胞に均等に供給して血糖値を正常に
維持する役割をするインシュリンが足りなくて、そのた
め血液中の糖分が十分に利用できず尿に混じって排泄さ
れてしまう病気である。
DISCLOSURE OF THE INVENTION Diabetes is caused by a lack of insulin, which plays a role in maintaining the blood sugar level by supplying sugars dissolved in the blood to each cell evenly. It is a disease that cannot be fully utilized and is excreted in urine.

【0007】しかし、膵臓が十分なインシュリンをつく
り出せない原因は、まだ完全に究められていない。一
方、従来の各天然薬材組成物は、上述のとおり、これと
いった効果をもたらさず、そのため一般的には利用され
るに到っていない。
However, the reason why the pancreas cannot produce sufficient insulin has not yet been completely investigated. On the other hand, each conventional natural drug composition does not bring about such effects as described above, and therefore has not been generally used.

【0008】そこで、糖尿病に対し、身体虚弱者、中で
も老人たちのために、刺激性や副作用のない天然薬材に
よる組成物を開発する必要性が日に日に増加しており、
これは今日由々しい課題となっている。
Therefore, there is an increasing need to develop a composition of natural medicines which is free of irritation and side effects for the physically weak and especially the elderly for diabetes.
This is a serious problem today.

【0009】[0009]

【課題を解決するための手段】本発明者は、長年月にわ
たって深く研究を重ねてきた甲斐あって、ここに血糖値
を短時日内に著しく減少させ、気を保し、しかも副作用
のない血糖値降下組成物を発明した。
[Means for Solving the Problems] The present inventor, who has been deeply researched for many years, is able to significantly reduce his blood glucose level within a short time, keep his mind, and have no side effects. Invented a depressant composition.

【0010】本発明は真珠、黄耆、黄精(竹幹の根)、
天花粉(Trichosanthes kirilowiiの根)、麦門冬、石
斛、牡丹皮(牡丹の根の皮)、丹参、しつれい、蔓参、
鶏内金および肉桂などの乾燥粉末からなり、1日3回、
1回に0.43gのカプセル7個を服用させることによ
り1〜3週間の服用で血糖量が240程度から正常値で
ある80〜140レベルに降下することを確認し、かた
わら人体投与量の286倍にあたる量を鼠に投与して観
察したところ正常であり却って毛に艶が出、体重も正常
に成長を続け毒性反応をあらわさないことが認められ
た。
The present invention includes pearls, yellow radish, yellow spirit (bamboo trunk root),
Heavenly pollen (Root of Trichosanthes kirilowii), Bakumon winter, Ishihan, Peony skin (peony root skin), Danshen, Shitsurei, Ginseng,
Consists of dried powder such as chicken inn and meat, 3 times a day,
By taking 7 capsules of 0.43g at a time, it was confirmed that the blood glucose level dropped from about 240 to the normal level of 80 to 140 after taking 1 to 3 weeks, while the human body dose of 286 When the mouse was administered in an amount equivalent to double the amount, it was observed that the hair was normal and the hair was glossy, and the body weight continued to grow normally and no toxic reaction was observed.

【0011】本発明に使用される真珠は、真珠貝の体内
で珠のように成形する分泌物の塊を粉末にして使用す
る。この薬剤は、精神安静、鎮静剤などとして知られて
いる。黄耆は、豆科に属する多年草の根であり、これを
乾かし粉末にして使用する。この薬剤は、利尿、止汗、
血圧降下などの効果が知られている。黄精は、竹幹の根
を乾燥粉末化したもので粘液質に富み、虚弱症、肺結核
性の咳、糖尿病による口渇きなどに対する効果が知られ
ている。天花粉は、ハヌルタリ(Trichosanthes kirilow
ii) の根を乾燥粉末化したもので、止渇、鎮咳、利尿な
どに利用される。麦門冬は、麦門アゼビ(ophiopogonace
ae) 科に属する多年草で根は太短く、消炎、鎮咳、消
渇、きょ痰、利尿などに使用される。石斛は、蘭科に属
する常緑多年草であって健胃強腸、鎮痛、止渇、病後衰
弱からの回復などのために用いられる。牡丹皮は、牡丹
の根の皮であって、鎮痛、鎮静および消炎薬、また更年
期の諸症状に使用されるものとして知られる。丹参は、
Labiatae科に属する多年草で中国に産してきょ炎、止痛
によく、また月経痛、産後の腹痛、リューマチなどの治
療薬剤として有用とされる。しつれいは、学名トリブル
ス・テレストリス(Tribulus terrestris )であって皮膚
病、眼病に煎じて服むこともあるが、血液の循環をよく
し血液の停滞を解く薬剤である。肉桂は、桂樹の厚い皮
であって健胃強腸剤として用いられる薬剤である。蔓参
は、桔梗科の多年生性蔓草である蔓参の根を乾かしたも
のであって、強壮作用、鎮咳、脾気虚症、虚弱症などに
用いられる。鶏内金は、鶏の消化器内にある黄味がかっ
た薄い膜であって、頻尿症、血尿、扁桃腺炎などに有用
な薬剤である。以下、本発明の実施例を通じて詳細に説
明する。
The pearls used in the present invention are powdered lumps of secretions which are shaped like beads in the body of pearl oysters. This drug is known as a tranquilizer and a sedative. Radix Astragali is a root of a perennial plant belonging to the legume family, which is dried and used as a powder. This drug is diuretic, antiperspirant,
It is known to have effects such as lowering blood pressure. Yellow sperm is a dry-powdered bamboo trunk root that is rich in mucus and is known to be effective against weakness, pulmonary tuberculous cough, and dry mouth caused by diabetes. Heavenly pollen is Trichosanthes kirilow
ii) is a dry powdered root and is used for thirst, antitussive and diuretic. Bakumon winter is the season for Bakumon azebi (ophiopogonace).
ae) It is a perennial herb belonging to the family and has a short root and is used for anti-inflammatory, antitussive, depleting, sputum, diuretic and the like. Ishisu is an evergreen perennial belonging to the family Orchidaceae and is used for healthy stomach and intestine, analgesia, thirst, recovery from post-illness weakness, etc. Peony skin is the root skin of peony and is known to be used for analgesic, sedative and anti-inflammatory drugs, as well as for menopausal symptoms. Danshen is
A perennial plant belonging to the Labiatae family, which is well-known for treating inflammation and pain in China and is useful as a therapeutic drug for menstrual pain, postpartum abdominal pain and rheumatism. The scientific name Tribulus terrestris is Tribulus terrestris, which is sometimes used to treat skin and eye diseases, but it is a drug that improves blood circulation and relieves blood stagnation. Cinnamon is a thick skin of cinnamon tree and is a drug used as a stomachic and intestinal agent. Ginseng is a dried root of Ginseng, which is a perennial vine of the bellflower family, and is used for tonic action, antitussive, splenic sinus, and weakness. Chicken inner gold is a yellowish thin film in the digestive organs of chickens and is a useful drug for pollakiuria, hematuria, tonsillitis, etc. Hereinafter, embodiments of the present invention will be described in detail.

【0012】[0012]

【実施例】真珠62重量部、黄耆147重量部、黄精1
47重量部、天花粉147重量部、麦門冬62重量部、
石斛62重量部、牡丹皮62重量部、丹参62重量部、
しつれい62重量部、蔓参62重量部、鶏内金62重量
部、肉桂62重量部の粉末を均等に混合の上、6号篩に
かけて漉し、それを直接服用できるようにカプセルに詰
める。
Example: 62 parts by weight of pearls, 147 parts by weight of Astragalus radix, 1 part of yellow spirit
47 parts by weight, 147 parts by weight of pollen, 62 parts by weight of Makumon winter,
62 parts by weight of Ishiba, 62 parts by weight of peony skin, 62 parts by weight of ginseng,
Powder of 62 parts by weight of shitsurei, 62 parts by weight of ginseng, 62 parts by weight of chicken inner gold, and 62 parts by weight of cinnamon bark is evenly mixed, strained through a No. 6 sieve, and packed into a capsule so that it can be directly taken.

【0013】[0013]

【発明の効果】このようにしてつくった血糖値降下組成
物を血糖値230〜250の中国人40人、韓国人20
人の計60人に1日3回、1回に0.43gのカプセル
7個を投与し、この期間中甘く辛い飲食物を禁じて観察
したところ、4名には別段の反応がなかったが、残りの
56人は1〜3週目に血糖値が半分に減り、その後の第
1週には却って若干上昇気味の後、さらにその1週後に
は正常値である80〜110レベルに降下して落ちつい
た。別段の反応を示さなかった4人中の1人は韓国人で
あった。
EFFECTS OF THE INVENTION The composition for lowering blood sugar level thus prepared was used in 40 Chinese people and 20 Korean people having a blood sugar level of 230-250.
A total of 60 people were administered 3 times a day with 7 0.43g capsules at a time, and during this period, we observed that sweet and spicy foods were prohibited. , The remaining 56 people had their blood sugar level halved in the 1st to 3rd weeks, then slightly increased in the 1st week, and then to the normal level of 80 to 110 in the 1st week. Calmed down. One out of four who did not show any particular reaction was Korean.

Claims (1)

【特許請求の範囲】[Claims] 【請求項1】 真珠50〜80重量部、黄耆120〜1
80重量部、黄精120〜180重量部、天花粉120
〜180重量部、麦門冬50〜80重量部、石斛50〜
80重量部、牡丹皮50〜80重量部、丹参50〜80
重量部、しつれい50〜80重量部、蔓参50〜80重
量部、鶏内金50〜80重量部、肉桂50〜80重量部
の粉末で組成することを特徴とする血糖値降下組成物。
1. A pearl of 50 to 80 parts by weight, and astragalus 120 to 1.
80 parts by weight, 120 to 180 parts by weight of yellow spirit, 120 pollen pollen
~ 180 parts by weight, Bakumon winter 50 ~ 80 parts by weight, Ishibiki 50 ~
80 parts by weight, peony skin 50-80 parts by weight, Danshen 50-80
A composition for lowering blood glucose level, characterized by being composed of powders of 50 parts by weight, 50-80 parts by weight of shitsurei, 50-80 parts by weight of ginseng, 50-80 parts by weight of chicken inner gold, and 50-80 parts by weight of cinnamon. .
JP5278857A 1993-07-23 1993-10-13 Composition for lowering blood glucose level Expired - Lifetime JPH0798753B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR14055/1993 1993-07-23
KR1019930014055A KR950002776A (en) 1993-07-23 1993-07-23 Hypoglycemic composition

Publications (2)

Publication Number Publication Date
JPH0733676A true JPH0733676A (en) 1995-02-03
JPH0798753B2 JPH0798753B2 (en) 1995-10-25

Family

ID=19359925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5278857A Expired - Lifetime JPH0798753B2 (en) 1993-07-23 1993-10-13 Composition for lowering blood glucose level

Country Status (2)

Country Link
JP (1) JPH0798753B2 (en)
KR (1) KR950002776A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071141B2 (en) 2000-12-12 2011-12-06 Kaneka Corporation Compositions for preventing or ameliorating multiple risk factor syndromes

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100416650B1 (en) * 2000-10-19 2004-02-05 신동수 Extract Polygonatum and composition caontaining the same with hypocholesterolemic and hypoglycemic activities
KR100793204B1 (en) * 2006-05-18 2008-01-10 동아대학교 산학협력단 Pharmaceutical Composition for Treating or Preventing Coronary Heart Diseases or Arteriosclerosis Containing an Extract of Chinese Herb as an Effective Ingredient
CN103212016A (en) * 2013-05-06 2013-07-24 张燕 Active biological enzyme extracting solution for treating diabetes wounds
CN104643078A (en) * 2015-02-15 2015-05-27 福建卫生职业技术学院 Compound dendrobium officinale health oral liquid and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071141B2 (en) 2000-12-12 2011-12-06 Kaneka Corporation Compositions for preventing or ameliorating multiple risk factor syndromes

Also Published As

Publication number Publication date
KR950002776A (en) 1995-02-16
JPH0798753B2 (en) 1995-10-25

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