CN1528401A - Pearl detoxifying oral liquid and preparing method tehreof - Google Patents

Pearl detoxifying oral liquid and preparing method tehreof Download PDF

Info

Publication number
CN1528401A
CN1528401A CNA2003101011382A CN200310101138A CN1528401A CN 1528401 A CN1528401 A CN 1528401A CN A2003101011382 A CNA2003101011382 A CN A2003101011382A CN 200310101138 A CN200310101138 A CN 200310101138A CN 1528401 A CN1528401 A CN 1528401A
Authority
CN
China
Prior art keywords
weight
weight portion
oral liquid
concentrated
carapax
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CNA2003101011382A
Other languages
Chinese (zh)
Other versions
CN1317007C (en
Inventor
卫 梁
梁卫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangxi Hebabiz Pharmaceutical Technology Co ltd
Original Assignee
BANZHOU PHARMACEUTICAL Co Ltd GUANGXI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BANZHOU PHARMACEUTICAL Co Ltd GUANGXI filed Critical BANZHOU PHARMACEUTICAL Co Ltd GUANGXI
Priority to CNB2003101011382A priority Critical patent/CN1317007C/en
Publication of CN1528401A publication Critical patent/CN1528401A/en
Application granted granted Critical
Publication of CN1317007C publication Critical patent/CN1317007C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention discloses a Chinese medicine Zhenzhu Jiedu Koufuye oral liquor for curing the diseases of cutaneous pruritus, acne and pimple with obvious therapeutic effect. Said Chinese medicine oral liquor is made up by using the Chinese medicinal materials of pearl powder, tortoise plastron, dried/fresh rehmannia root, lonicera flower, smooth greenbrier root and licorice. Its total effective rate is 90.1%.

Description

A kind of Margarita Jiedu oral liquid and preparation method
Technical field
What the present invention relates to is a kind of nourishing YIN and clearing away heat antidotal pharmaceutical preparation that has, and is the Chinese patent medicine of primary raw material with Margarita, Carapax et Plastrum Testudinis specifically, the invention still further relates to the preparation method of this medicine.
Background technology
Disease on the various women's head-ornaments skins such as skin pruritus, acne, acne is a kind of because of the vehement commonly encountered diseases frequently-occurring disease that causes in interior-heat caused by deficiency of YIN, the pyretic toxicity.For these diseases, present treatment means is to use antihistaminic medicine, salicylic acid esters medicine, ethoxybenzene class medicine is mixed with medicine for external use embrocates, or is prepared into medicine for external use with Chinese medicine and embrocates.As application number be: 01114154.9 Chinese invention patent, the lotion and the production method of treatment skin pruritus are prepared into liquid medicine with Radix Angelicae Sinensis, Fructus Toosendan, Flos Caryophylli, Folium Artemisiae Argyi, Semen Raphani, Alumen, Scolopendra, vinegar exactly, and reuse liquid medicine is embrocated the affected part.Medicine for external use is more effective to skin pruritus, because it is a symptomatic treatment, medicine for external use also is a kind of method of taking stopgap measures but then, takes stopgap measures and does not effect a permanent cure, often easily recurrence, outbreak repeatedly causes sufferings even more serious, if acne on the women's head-ornaments or pruritus use medicine for external use can stay cicatrix, influence the attractive in appearance of face, thereby this is not a kind of ideal method.Using Chinese patent medicine orally taken for curing acne and skin pruritus is a kind of good method.Application number is 00112871.x, respectively be called: a kind of Chinese invention patent application for the treatment of dermopathic medicine and preparation method thereof, a kind of Chinese patent medicine of treatment skin pruritus for oral administration is disclosed exactly, it is made up of 17 flavor Chinese medicines such as Indigo Naturalis, Radix Isatidis, Herba Portulacae, to the drying property skin pruritus is more effective, but skin pruritus due to interior-heat caused by deficiency of YIN and facial remedy of acne are still existed certain deficiency.In addition, find no the report of other orally taken for curing facial acne that interior-heat caused by deficiency of YIN causes and skin pruritus.
Summary of the invention
Purpose of the present invention prepares a kind of treatment exactly because of interior-heat caused by deficiency of YIN in the body, vehement and women's head-ornaments that cause, the medicine of dermatosis in the pyretic toxicity; Another object of the present invention just provides the method for this medicine of preparation.
For achieving the above object, the present invention has taked such measure, and a kind of Margarita Jiedu oral liquid is prepared from by the following weight proportion raw material:
Margarita layer powder 7-15 weight portion Carapax et Plastrum Testudinis 1-3.5 weight portion Radix Rehmanniae 6-18 weight portion
Flos Lonicerae 1-3.5 weight portion Rhizoma Smilacis Glabrae 6-18 weight portion
The preferred weight ratio range of raw material of the present invention is:
Margarita layer powder 8-12 weight portion Carapax et Plastrum Testudinis 1-2 weight portion Radix Rehmanniae 8-12 weight portion
Flos Lonicerae 1-2 weight portion Rhizoma Smilacis Glabrae 8-12 weight portion
Optimum weight proportioning of the present invention is:
Margarita layer powder 10 weight portion Carapax et Plastrum Testudiniss 2 weight portion Radix Rehmanniae 10 weight portions
Flos Lonicerae 2 weight portion Rhizoma Smilacis Glabraes 10 weight portions
The present invention can add Radix Glycyrrhizae 1-3.5 weight portion.
Margarita layer powder of the present invention refers to sea water pearls, mussel pearl and their pearl shellfish endoplasm layer and pulverizes the fine powder that forms.
Preparation method of the present invention comprises the steps:
1, extracting honeysuckle, Rhizoma Smilacis Glabrae, Radix Rehmanniae and Radix Glycyrrhizae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated, at the uniform velocity to carry out percolation, the percolate that the 5-10 of collection above-mentioned raw materials weight doubly measures, reclaiming ethanol and being concentrated into above-mentioned raw materials weight ratio percolate weight is 1: 1.2, and it is standby to obtain concentrated solution (1).
2, getting Margarita layer powder, to add distilled water an amount of, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1-1.2, it is standby to obtain concentrated solution (2).
3, get Carapax et Plastrum Testudinis and add water heating and decoct 2-5 time, and collect and merge each time decoction liquor, filtration, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, it is standby to get concentrated solution (3).
4, merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 10-24 hour, filter, filtrate and simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain the present invention of 90-110 part.
Take the present invention of above-mentioned measure, replenishing YIN and removing heat is arranged, removing pathogenic heat from blood and toxic substance from the body removes the nebula effect, can be used for treating that powder is perverse, skin pruritus, miliaria, furuncle carbuncle, the turbid dim eyesight of order, also can improve looks skin moistening, skin care.This is because deficiency of YIN blood is dry, loses it and supports, then can slightly split by skin, and skin pruritus, order is given birth to cataracta, and is vehement in the pyretic toxicity, stops up the QI and blood that stagnates, and the carbuncle furuncle is grown thickly.And the Margarita layer powder salty in the mouth among the present invention is cold in nature, clearing away heat to improve acuity of vision, and yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and detoxifcation removes nebula, is aided with the Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; The Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone, the reinforcing the heart of nourishing blood; The Flos Lonicerae clearing away heat,cooling blood and removing toxin, Rhizoma Smilacis Glabrae detoxifcation dehumidifying, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, thereby make the present invention that replenishing YIN and removing heat be arranged, the effect of removing pathogenic heat from blood and toxic substance from the body.216 routine clinical trials prove, the present invention is perverse to the powder of wind and heat in the lung meridian card or the intestines and stomach damp-heat syndrome, and the pruritus caused by wind pathogen and the miliaria of wind heat blood-heat syndrome had therapeutical effect, and symptom after taking medicine improves obviously.The effective percentage of, pruritus caused by wind pathogen perverse to powder, miliaria is respectively 86.2%, 89.1% and 100%.The total effective rate of three kinds of diseases is 90.1%.
Embodiment
Embodiment 1
Prescription
Margarita layer powder 70 gram Carapax et Plastrum Testudiniss 10 gram Radix Rehmanniae 60 grams
Flos Lonicerae 10 gram Rhizoma Smilacis Glabraes 60 gram Radix Glycyrrhizaes 10 grams
Preparation method
1, extracting honeysuckle, Rhizoma Smilacis Glabrae, Radix Rehmanniae and Radix Glycyrrhizae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated 24 hours, carry out percolation with per minute 1-3 milliliter speed, collect the percolate that the 5-10 of above-mentioned raw materials weight doubly measures, reclaim ethanol and be condensed into the above-mentioned raw materials weight ratio be that 1: 1 concentrated solution (1) is standby.
2, getting Margarita layer powder, to add distilled water an amount of, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1-1.2, it is standby to obtain concentrated solution (2).
3, get Carapax et Plastrum Testudinis processing and turn round and look at little bulk, add the water heating and decoct 5 times, each 1.5-2 hour, collect and merge each time decoction liquor, filter, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, it is standby to get concentrated solution (3).
4, merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 24 hours, filter, filtrate and hot simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain 900 milliliters of part the present invention.
Embodiment 2
Prescription
Margarita layer powder 150 gram Carapax et Plastrum Testudiniss 35 gram Radix Rehmanniae 160 grams
Flos Lonicerae 35 gram Rhizoma Smilacis Glabraes 150 gram Radix Glycyrrhizaes 35 grams
Preparation method:
Preparation method is identical with embodiment 1 preparation method, and obtains 1100 milliliters of the present invention.
Embodiment 3
Prescription
Margarita layer powder 100 gram Carapax et Plastrum Testudiniss 20 gram Radix Rehmanniae 100 grams
Flos Lonicerae 20 gram Rhizoma Smilacis Glabraes 100 gram Radix Glycyrrhizaes 20 grams
Preparation method:
Preparation method is identical with embodiment 1 preparation method, and obtains 1000 milliliters of the present invention.
Embodiment 4
Prescription
Margarita layer powder 70 gram Carapax et Plastrum Testudiniss 10 gram Radix Rehmanniae 60 grams
Flos Lonicerae 10 gram Rhizoma Smilacis Glabraes 60 grams
Preparation method
1, extracting honeysuckle, Rhizoma Smilacis Glabrae and Radix Rehmanniae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated 24 hours, carry out percolation with per minute 1-3 milliliter speed, collect the percolate that the 5-10 of above-mentioned raw materials weight doubly measures, reclaim ethanol and be condensed into the above-mentioned raw materials weight ratio be that 1: 1 concentrated solution (1) is standby.
2, all the other preparation methoies are identical with embodiment 1 method, and obtain 900 milliliters of the present invention.

Claims (5)

1, a kind of Margarita Jiedu oral liquid is characterized in that described oral liquid is prepared from by the following weight proportion raw material:
Margarita layer powder 7-15 weight portion Carapax et Plastrum Testudinis 1-3.5 weight portion Radix Rehmanniae 6-18 weight portion
Flos Lonicerae 1-3.5 weight portion Rhizoma Smilacis Glabrae 6-18 weight portion
2, oral liquid according to claim 1 is characterized in that the preferred weight ratio range of the raw material of described oral liquid is:
Margarita layer powder 8-12 weight portion Carapax et Plastrum Testudinis 1-2 weight portion Radix Rehmanniae 8-12 weight portion
Flos Lonicerae 1-2 weight portion Rhizoma Smilacis Glabrae 8-12 weight portion
3, oral liquid according to claim 1 is characterized in that the optimum weight proportioning of the raw material of described oral liquid is:
Margarita layer powder 10 weight portion Carapax et Plastrum Testudiniss 2 weight portion Radix Rehmanniae 10 weight portions
Flos Lonicerae 2 weight portion Rhizoma Smilacis Glabraes 10 weight portions
4,, it is characterized in that having added in the described oral liquid Radix Glycyrrhizae 1-3.5 weight portion according to claim 1,2 or 3 described oral liquids.
5, the preparation method of the described a kind of Margarita Jiedu oral liquid of claim 4 is characterized in that described method comprises the steps:
1. extracting honeysuckle, Rhizoma Smilacis Glabrae, Radix Rehmanniae and Radix Glycyrrhizae, pulverize separately becomes coarse powder, with the alcohol amount of containing is that the ethanol of 50-60% is solvent impregnated, at the uniform velocity to carry out percolation, the percolate that the 5-10 of collection above-mentioned raw materials weight doubly measures, reclaiming ethanol and being concentrated into above-mentioned raw materials weight ratio percolate weight is 1: 1.2, and it is standby to get concentrated solution (1).
2. it is an amount of to get Margarita layer powder adding distilled water, stir evenly, it is an amount of to add concentrated hydrochloric acid, and the limit edged stirs, and does not produce to there being steam bubble, all till the dissolving, add several times amount distilled water and stirring again, can separate out jelly this moment, gets supernatant and discard, repeatedly with distilled water wash and abandoning supernatant, till the no calcium reaction of detection, collect jelly, add appropriate hydrochloric acid, reflux 15-30 hour, after cold, take out mother solution, reheat drives de-chlorine hydride gas, being concentrated into Margarita layer powder weight ratio mother solution weight is 1: 1.2, and it is standby to obtain concentrated solution (2).
3. get Carapax et Plastrum Testudinis and add water heating decoction 2-5 time, and collect each time of merging decoction liquor, filter, it is 1: 1.2 that filtrate is concentrated into Carapax et Plastrum Testudinis weight ratio filtrate weight, and it is standby to obtain concentrated solution (3).
4. merge above-mentioned three kinds of concentrated solutions (1), (2), (3), add one times of amount distilled water and boil, placed 10-24 hour, filter, filtrate and simple syrup mixing are transferred PH to 4.5-5.5 with alkali, obtain the present invention of 90-110 part.
CNB2003101011382A 2003-10-17 2003-10-17 Pearl detoxifying oral liquid and preparing method tehreof Expired - Fee Related CN1317007C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2003101011382A CN1317007C (en) 2003-10-17 2003-10-17 Pearl detoxifying oral liquid and preparing method tehreof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2003101011382A CN1317007C (en) 2003-10-17 2003-10-17 Pearl detoxifying oral liquid and preparing method tehreof

Publications (2)

Publication Number Publication Date
CN1528401A true CN1528401A (en) 2004-09-15
CN1317007C CN1317007C (en) 2007-05-23

Family

ID=34304176

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2003101011382A Expired - Fee Related CN1317007C (en) 2003-10-17 2003-10-17 Pearl detoxifying oral liquid and preparing method tehreof

Country Status (1)

Country Link
CN (1) CN1317007C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101336971B (en) * 2008-06-06 2011-09-21 孙瑞龙 Oral traditional Chinese medicine for treating milium
CN105833079A (en) * 2016-05-05 2016-08-10 宋云飞 Drug for treating wind itching
CN114081908A (en) * 2021-10-20 2022-02-25 湖南省开元博物馆 Antipruritic composition, application thereof and external antipruritic

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1148216C (en) * 2001-04-28 2004-05-05 周美妮 Medicine for curing acne and sore

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101336971B (en) * 2008-06-06 2011-09-21 孙瑞龙 Oral traditional Chinese medicine for treating milium
CN105833079A (en) * 2016-05-05 2016-08-10 宋云飞 Drug for treating wind itching
CN114081908A (en) * 2021-10-20 2022-02-25 湖南省开元博物馆 Antipruritic composition, application thereof and external antipruritic

Also Published As

Publication number Publication date
CN1317007C (en) 2007-05-23

Similar Documents

Publication Publication Date Title
CN1051237C (en) Meicinal prepn. "Kexianling" for curing epilepsy
CN102225138A (en) Traditional Chinese medicine composition for treating fracture and preparation method and application thereof
CN101590168B (en) Traditional Chinese medicine combination for treating gout and preparation method thereof
CN102379941B (en) A kind of compound Chinese medicinal preparation treating fracture and preparation method thereof
CN102671178B (en) Preparation method of Chinese medicinal composition for treating nephrotic syndrome and uremia and application thereof
CN1317007C (en) Pearl detoxifying oral liquid and preparing method tehreof
CN1903329A (en) Traditional Chinese medicine for treating chronic periodontitis
CN1827136A (en) Compound Chinese medicinal preparation for treating male sterility
CN101590166B (en) Traditional Chinese medicine combination for treating gout and preparation method thereof
CN1895593A (en) Medicine for treating acne and its preparation
CN1712060A (en) Preparation of Chinese medicinal mixture for treating gynecologic menstrual disease
CN1840170A (en) Chinese proprietary medicine for treating cerebral thrombosis
CN1233410C (en) External use medicine for bone-knitting
CN1127344C (en) Oral pill for curing diabetes and its complication
CN1403119A (en) Medicine for treating cerebral thrombus and its prepn
CN1183953C (en) Medicine for clearing away heat and toxic matter, promoting diuresis and stopping itching
CN115300554B (en) Traditional Chinese medicine preparation for promoting blood circulation to remove meridian obstruction and preparation method thereof
CN1264592A (en) Medicine for treating ichthyosis and preparing process thereof
CN101327283B (en) Composite medicine for treating nephrosis and its preparing process
CN102228661B (en) Chinese medicinal cholecystitis treatment mixture for treating chronic cholecystitis
CN1246019C (en) Chinese medicine preparation for curing angitis
CN1060214A (en) The preparation method of kidney and relieve asthma Chinese medicine patent medicine
CN1141183A (en) Compound Vernonia anthelmintica tablet for treating vitiligo
CN1153585C (en) Instant Chinese medicine for treating intestinal adhesion and its preparing process
CN1712039A (en) Chinese and Mongolia medicinal composition and its preparing method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C57 Notification of unclear or unknown address
DD01 Delivery of document by public notice

Addressee: Pang Fuwang

Document name: Resume right request approval decision

C57 Notification of unclear or unknown address
DD01 Delivery of document by public notice

Addressee: Pang Fuwang

Document name: Notification to Pay the Fees

PP01 Preservation of patent right

Effective date of registration: 20090513

Pledge (preservation): Preservation

PD01 Discharge of preservation of patent

Date of cancellation: 20091113

Pledge (preservation): Preservation registration

PP01 Preservation of patent right

Effective date of registration: 20100624

Granted publication date: 20070523

PD01 Discharge of preservation of patent

Date of cancellation: 20101224

Granted publication date: 20070523

PP01 Preservation of patent right

Effective date of registration: 20110315

Granted publication date: 20070523

PD01 Discharge of preservation of patent

Date of cancellation: 20110915

Granted publication date: 20070523

ASS Succession or assignment of patent right

Owner name: GUANGXI HUIBAOYUAN PHARMACEUTICAL CO., LTD.

Free format text: FORMER OWNER: BANZHOU PHARMACEUTICAL CO LTD, GUANGXI

Effective date: 20120229

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20120229

Address after: Qinzhou city the Guangxi Zhuang Autonomous Region 535000 min Street No. 76

Patentee after: GUANGXI HEBABIZ PHARMACEUTICAL Co.,Ltd.

Address before: 535000 No. 75 Qinzhou Bay Road, the Guangxi Zhuang Autonomous Region, Qinzhou

Patentee before: Guangxi Banzhou Pharmaceutical Co.,Ltd.

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160218

Address after: 535008, Ma 1 Street, Qinzhou Industrial Park, Qinzhou, the Guangxi Zhuang Autonomous Region

Patentee after: GUANGXI HEBABIZ PHARMACEUTICAL TECHNOLOGY Co.,Ltd.

Address before: Qinzhou city the Guangxi Zhuang Autonomous Region 535000 min Street No. 76

Patentee before: GUANGXI HEBABIZ PHARMACEUTICAL Co.,Ltd.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070523

Termination date: 20211017